Inchoate CD8+ T cell responses in neonatal mice permit influenza-induced persistent pulmonary dysfunction

Journal of Immunology

Volumn 181, Issue 5, 2008, Pages 3486-3494

  You, Dahui ^a,b   Ripple, Michael ^b   Balakrishna, Shrilatha ^a   Troxclair, Dana ^a   Sandquist, Dane ^a   Ding, Liren ^a,c   Ahlert, Terry A ^a   Cormier, Stephania A ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOUISIANA STATE UNIVERSITY   (United States)

^c THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON;

ADAPTIVE IMMUNITY; ADOPTIVE TRANSFER; AIRWAY RESISTANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD8+ T LYMPHOCYTE; CHRONIC DISEASE; CONTROLLED STUDY; DISEASE SEVERITY; EMPHYSEMA; IMMUNE RESPONSE; IMMUNE SYSTEM; INFANCY; INFLUENZA; INFLUENZA VIRUS A; LUNG DISEASE; LUNG FUNCTION; LUNG INFECTION; LUNG LESION; LYMPHOCYTE SUBPOPULATION; MOUSE; NEWBORN; NEWBORN PERIOD; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; VACCINATION; AGE; ANIMAL; DISEASE MODEL; HUMAN; IMMUNOLOGY; LUNG EMPHYSEMA; MOUSE MUTANT; PATHOLOGY; RESPIRATORY TRACT ALLERGY; TRANSPLANTATION; TREATMENT OUTCOME; VIROLOGY;

ADOPTIVE TRANSFER; AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; CD8-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; HUMANS; INFLUENZA A VIRUS; INTERFERON TYPE II; LUNG DISEASES; MICE; MICE, KNOCKOUT; PNEUMONIA; PULMONARY EMPHYSEMA; RESPIRATORY HYPERSENSITIVITY; TREATMENT OUTCOME;

EID: 51549111662     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.181.5.3486     Document Type: Article

References (43)

1. Monto, A. S. 2000. Epidemiology and virology of influenza illness: based on a presentation by Arnold S. Monto, MD. Am. J. Manag. Care 6: S255-S264.
2. Upshur, R. E., R. Moineddin, E. J. Crighton, and M. Mamdani. 2006. Interactions of viral pathogens on hospital admissions for pneumonia, croup and chronic obstructive pulmonary diseases: results of a multivariate time-series analysis. Epidemiol. Infect. 134: 1174-1178.
3. Glezen, W. P. 1996. Emerging infections: pandemic influenza. Epidemiol. Rev. 18: 64-76.
4. Glezen, W. P., L. H. Taber, A. L. Frank, W. C. Gruber, and P. A. Piedra. 1997. Influenza virus infections in infants. Pediatr. Infect. Dis. J. 16: 1065-1068.
5. Collins, S. D., and J. Lehmann. 1951. Trends and epidemics of influenza and pneumonia: 1918-1951. Public Health Rep. 66: 1487-1516.
6. Chin, T. D., J. F. Foley, I. L. Doto, C. R. Gravelle, and J. Weston. 1960. Morbidity and mortality characteristics of Asian strain influenza. Public Health Rep. 75: 148-158.
7. Bhat, N., J. G. Wright, K. R. Broder, E. L. Murray, M. E. Greenberg, M. J. Glover, A. M. Likos, D. L. Posey, A. Klimov, S. E. Lindstrom, et al. 2005. Influenza-associated deaths among children in the United States, 2003-2004. N. Engl. J. Med. 353: 2559-2567. (Pubitemid 41785893)
8. Ajayi-Obe, E. K., P. G. Coen, R. Handa, K. Hawrami, C. Aitken, E. D. McIntosh, and R. Booy. 2007. Influenza A and respiratory syncytial virus hospital burden in young children in East London. Epidemiol. Infect. 136: 1046-1058.
9. Neuzil, K. M., Y. W. Zhu, M. R. Griffin, K. M. Edwards, J. M. Thompson, S. J. Tollefson, and P. F. Wright. 2002. Burden of interpandemic influenza in children younger than 5 years: a 25-year prospective study. J. Infect. Dis. 185: 147-152.
10. Laraya-Cuasay, L. R., A. DeForest, D. Huff, H. Lischner, and N. N. Huang. 1977. Chronic pulmonary complications of early influenza virus infection in children. Am. Rev. Respir. Dis. 116: 617-625.
11. Eichelberger, M. C. 2007. The cotton rat as a model to study influenza pathogenesis and immunity. Viral Immunol. 20: 243-249.
12. Bender, B. S., T. Croghan, L. Zhang, and P. A. Small, Jr. 1992. Transgenic mice lacking class I major histocompatibility complex-restricted T cells have delayed viral clearance and increased mortality after influenza virus challenge. J. Exp. Med. 175: 1143-1145.
13. Graham, M. B., and T. J. Braciale. 1997. Resistance to and recovery from lethal influenza virus infection in B lymphocyte-deficient mice. J. Exp. Med. 186: 2063-2068. (Pubitemid 28013692)
14. Epstein, S. L., C. Y. Lo, J. A. Misplon, and J. R. Bennink. 1998. Mechanism of protective immunity against influenza virus infection in mice without antibodies. J. Immunol. 160: 322-327. (Pubitemid 28116745)
15. Pullan, C. R., and E. N. Hey. 1982. Wheezing, asthma, and pulmonary dysfunction 10 years after infection with respiratory syncytial virus in infancy. Br. Med. J. 284: 1665-1669.
16. Sigurs, N., P. M. Gustafsson, R. Bjarnason, F. Lundberg, S. Schmidt, F. Sigurbergsson, and B. Kjellman. 2005. Severe respiratory syncytial virus bronchiolitis in infancy and asthma and allergy at age 13. Am. J. Respir. Crit. Care Med. 171: 137-141. (Pubitemid 40105412)
17. Sigurs, N., R. Bjarnason, F. Sigurbergsson, and B. Kjellman. 2000. Respiratory syncytial virus bronchiolitis in infancy is an important risk factor for asthma and allergy at age 7. Am. J. Respir. Crit. Care Med. 161: 1501-1507. (Pubitemid 30329018)
18. Culley, F. J., J. Pollott, and P. J. Openshaw. 2002. Age at first viral infection determines the pattern of T cell-mediated disease during reinfection in adulthood. J. Exp. Med. 196: 1381-1386.
19. Dakhama, A., J. W. Park, C. Taube, A. Joetham, A. Balhorn, N. Miyahara, K. Takeda, and E. W. Gelfand. 2005. The enhancement or prevention of airway hyperresponsiveness during reinfection with respiratory syncytial virus is critically dependent on the age at first infection and IL-13 production. J. Immunol. 175: 1876-1883. (Pubitemid 41023094)
20. You, D., D. Becnel, K. Wang, M. Ripple, M. Daly, and S. A. Cormier. 2006. Exposure of neonates to respiratory syncytial virus is critical in determining subsequent airway response in adults. Respir. Res. 7: 107. (Pubitemid 44355985)
21. Welliver, T. P., R. P. Garofalo, Y. Hosakote, K. H. Hintz, L. Avendano, K. Sanchez, L. Velozo, H. Jafri, S. Chavez-Bueno, P. L. Ogra, et al. 2007. Severe human lower respiratory tract illness caused by respiratory syncytial virus and influenza virus is characterized by the absence of pulmonary cytotoxic lymphocyte responses. J. Infect. Dis. 195: 1126-1136.
22. National Research Council. 1996. Guide for the Care and Use of Laboratory Animals. National Academic Press, Washington, DC.
23. Kärber, G. 1931. Beitrag zur kollektiven behandlung pharmakologischer reihenversuche. Arch. Exp. Path. Pharmak. 162: 480-483.
24. Spearman, C. 1908. The method of right and wrong cases (constant stimuli) without Gauss's formulae. Br. J. Psychol. 2: 227-242.
25. Thurlbeck, W. M. 1967. Measurement of pulmonary emphysema. Am. Rev. Respir. Dis. 95: 752-764.
26. Saetta, M., R. J. Shiner, G. E. Angus, W. D. Kim, N. S. Wang, M. King, H. Ghezzo, and M. G. Cosio. 1985. Destructive index: a measurement of lung parenchymal destruction in smokers. Am. Rev. Respir. Dis. 131: 764-769. (Pubitemid 15066865)
27. Ormerod, M. G. 2000. Preparing suspensions of single cells. In Flow Cytometry: A Practical Approach, 3rd Ed. M. G. Ormerod, ed. Oxford University Press, Oxford, pp. 35-46.
28. Wells, M. A., F. A. Ennis, and P. Albrecht. 1981. Recovery from a viral respiratory infection: II. Passive transfer of immune spleen cells to mice with influenza pneumonia. J. Immunol. 126: 1042-1046. (Pubitemid 11155752)
29. Billingham, R. E., L. Brent, and P. B. Medawar. 1953. Actively acquired tolerance of foreign cells. Nature 172: 603-606.
30. Bona, C. 2005. Neonatal Immunity. Humana Press, Totowa, NJ.
31. Adkins, B. 1999. T-cell function in newborn mice and humans. Immunol. Today 20: 330-335. (Pubitemid 29331539)
32. Granberg, C., T. Hirvonen, and P. Toivanen. 1979. Cell-mediated lympholysis by human maternal and neonatal lymphocytes: mother's reactivity against neonatal cells and vice versa. J. Immunol. 123: 2563-2567. (Pubitemid 10218050)
33. Yarchoan, R., and D. L. Nelson. 1983. A study of the functional capabilities of human neonatal lymphocytes for in vitro specific antibody production. J. Immunol. 131: 1222-1228.
34. Velilla, P. A., M. T. Rugeles, and C. A. Chougnet. 2006. Defective antigen-presenting cell function in human neonates. Clin. Immunol. 121: 251-259. (Pubitemid 44768008)
35. Bruder, D., A. Srikiatkhachorn, and R. I. Enelow. 2006. Cellular immunity and lung injury in respiratory virus infection. Viral Immunol. 19: 147-155. (Pubitemid 44050313)
36. + cytotoxic T cells to virus clearance or pathologic manifestations of influenza virus infection in a T cell receptor transgenic mouse model. J. Exp. Med. 188: 223-232.
37. Wiley, J. A., A. Cerwenka, J. R. Harkema, R. W. Dutton, and A. G. Harmsen. 2001. Production of interferon-γ by influenza hemagglutinin-specific CD8 effector T cells influences the development of pulmonary immunopathology. Am. J. Pathol. 158: 119-130.
38. Adkins, B., Y. Bu, E. Cepero, and R. Perez. 2000. Exclusive Th2 primary effector function in spleens but mixed Th1/Th2 function in lymph nodes of murine neonates. J. Immunol. 164: 2347-2353. (Pubitemid 30115461)
39. Adkins, B., K. Chun, K. Hamilton, and M. Nassiri. 1996. Naive murine neonatal T cells undergo apoptosis in response to primary stimulation. J. Immunol. 157: 1343-1349. (Pubitemid 126449070)
40. Adkins, B., A. Ghanei, and K. Hamilton. 1993. Developmental regulation of IL-4, IL-2, and IFN-γ production by murine peripheral T lymphocytes. J. Immunol. 151: 6617-6626. (Pubitemid 24001036)
41. Min, B., K. L. Legge, C. Pack, and H. Zaghouani. 1998. Neonatal exposure to a self-peptide-immunoglobulin chimera circumvents the use of adjuvant and confers resistance to autoimmune disease by a novel mechanism involving interleukin 4 lymph node deviation and interferon γ-mediated splenic anergy. J. Exp. Med. 188: 2007-2017. (Pubitemid 28562518)
42. Pack, C. D., A. E. Cestra, B. Min, K. L. Legge, L. Li, J. C. Caprio-Young, J. J. Bell, R. K. Gregg, and H. Zaghouani. 2001. Neonatal exposure to antigen primes the immune system to develop responses in various lymphoid organs and promotes bystander regulation of diverse T cell specificities. J. Immunol. 167: 4187-4195.
43. Didierlaurent, A., J. Goulding, S. Patel, R. Snelgrove, L. Low, M. Bebien, T. Lawrence, L. S. van Rijt, B. N. Lambrecht, J. C. Sirard, and T. Hussell. 2008. Sustained desensitization to bacterial Toll-like receptor ligands after resolution of respiratory influenza infection. J. Exp. Med. 205: 323-329. (Pubitemid 351281598)