Pathophysiology of pain in venous disease

Phlebolymphology

Volumn 15, Issue 3, 2008, Pages 107-114

  Danziger, Nicolas ^a  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

Chronic venous disease; Inflammation; Pain

Indexed keywords

CATECHOL METHYLTRANSFERASE;

ARTICLE; DISEASE COURSE; DISEASE SEVERITY; HUMAN; INDIVIDUALIZATION; INFLAMMATION; LEG CRAMP; LEG PAIN; LEG SWELLING; MICROANGIOPATHY; NEUROPHYSIOLOGY; NOCICEPTION; NOCICEPTIVE RECEPTOR; NONHUMAN; PAIN; PATHOPHYSIOLOGY; PRURITUS; QUALITY OF LIFE; SENSORY NEUROPATHY; SYMPTOMATOLOGY; UNPLEASANT SENSATION; VARICOSIS; VEIN DISEASE;

EID: 51549095357     PISSN: 12860107     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Bradbury A, Evans C, Allan P, Lee A, Ruckley CV, Fowkes FG. What are the symptoms of varicose veins? Edinburgh vein study cross sectional population survey. BMJ. 1999;318:353-356.
2. Allaert FA. Evolution des tableaux cliniques de l'insuffisance veineuse chronique en fonction de son ancienneté. Angéiologie. 2002;54:1.
3. Launois R, Reboul-Marty J, Henry B. Construction and validation of a quality of life questionnaire in chronic lower limb venous insufficiency (CIVIQ). Qual Life Res. 1996;5:539-554.
4. Andreozzi GM, Cordova RM, Scomparin A, Martini R, D'Eri A, Andreozzi F. Quality of life in chronic venous insufficiency. An Italian pilot study of the Triveneto Region. Int Angiol. 2005;24:272-277.
5. Arndt JO, Klement W. Pain evoked by polymodal stimulation of hand veins in humans. J Physiol. 1991;440:467.
6. Michiels C, Arnould T, Thibaut-Vercruyssen R, Bouaziz N, Janssens D, Remacle J. Perfused human saphenous veins for the study of the origin of varicose veins: role of the endothelium and of hypoxia. Int Angiol. 1997; 16:134-141.
7. Michiels C, Bouaziz N, Remacle J. Role of the endothelium and blood stasis in the development of varicose veins. Int Angiol. 2002;21:18-25.
8. Jacob MP, Cazaubon M, Scemama A, et al. Plasma matrix metalloproteinase-9 as a marker of blood stasis in varicose veins. Circulation. 2002;106:535-538.
9. Klement W, Arndt JO. Pain but no temperature sensations are evoked by thermal stimulation of cutaneous veins in man. Neurosci Lett. 1991;123:119-122.
10. Michaelis M, Goder R, Habler HJ, Janig W. Properties of afferent nerve fibres supplying the saphenous vein in the cat. J Physiol. 1994;474:233-243.
11. Klement W, Arndt JO. Adenosine does not evoke pain from venous and paravascular nociceptors in the human. Cardiovasc Res. 1992;26:186-189.
12. Eklof B, Rutherford RB, Bergan JJ, et al. American Venous Forum International Ad Hoc Committee for Revision of the CEAP Classification. Revision of the CEAP classification for chronic venous disorders: consensus statement. J Vasc Surg. 2004; 40:1248-1252.
13. Bradbury A, Evans CJ, Allan P, Lee AJ, Ruckley CV, Fowkes FG. The relationship between lower limb symptoms and superficial and deep venous reflux on duplex ultrasonography: The Edinburgh Vein Study. J Vasc Surg. 2000;32:921-931.
14. Duque MI, Yosipovitch G, Chan YH, Smith R, Levy P. Itch, pain, and burning sensation are common symptoms in mild to moderate chronic venous insufficiency with an impact on quality of life. J Am Acad Dermatol. 2005;53:504-508.
15. Howlader MH, Smith PD. Symptoms of chronic venous disease and association with systemic inflammatory markers. J Vasc Surg. 2003;38:950-954.
16. Widmer LK, Zemp E. Diagnosis and treatment of varicose veins. Deductions from on a Basel prospective epidemiological study. Helv Chir Acta. 1988;54:531-539.
17. Badier-Commandier C, Jacob MP, Michel JB. Le remodelage variqueux. Médecine Thérapeutique. 2000;6:718-723.
18. Arnould T, Janssens D, Michiels C, Remacle J. Effect of aescine on hypoxia-induced activation of human endothelial cells. Eur J Pharmacol. 1996;315:227-233.
19. Michiels C, Renard P, Bouaziz N, et al. Identification of the phospholipase A(2) isoforms that contribute to arachidonic acid release in hypoxic endothelial cells: limits of phospholipase A(2) inhibitors. Biochem Pharmacol. 2002;63:321-332.
20. Michiels C, Arnould T, Knott I, Dieu M, Remacle J. Stimulation of prostaglandin synthesis by human endothelial cells exposed to hypoxia. Am J Physiol. 1993;264:C866-C874.
21. Michiels C, Arnould T, Remacle J. Hypoxia-induced activation of endothelial cells as a possible cause of venous diseases: hypothesis. Angiology. 1993;44:639-646.
22. Bergan JJ, Schmid-Schonbein GW, Smith PD, Nicolaides AN, Boisseau MR, Eklof B. Chronic venous disease. N Engl J Med. 2006;355:488-498.
23. Smith PD. Update on chronic-venous-insufficiency-induced inflammatory processes. Angiology. 2001;52:S35-S42. Review.
24. Takase S, Schmid-Schonbein GW, Bergan JJ. Leukocyte activation in patients with venous insufficiency. J Vasc Surg. 1999;30:148-156.
25. Junger M, Steins A, Hahn M, Hafner HM. Microcirculatory dysfunction in chronic venous insufficiency (CVI). Microcirculation. 2000;7:S3-S12.
26. Saharay M, Shields DA, Porter JB, Scurr JH, Coleridge Smith PD. Leucocyte activity in the microcirculation of the leg in patients with chronic venous disease. J Vasc Surg. 1997;26:265-273.
27. Schmid-Schönbein GW. Inflammation and the pathophysiology of chronic venous insufficiency. Phlebolymphology. 2003;39:95-99.
28. Kindgen-Milles D, Klement W, Arndt JO. The nociceptive systems of skin, paravascular tissue and hand veins of humans and their sensitivity to bradykinin. Neurosci Lett. 1994;181:39-42.
29. Holthusen H, Arndt JO. Nitric oxide evokes pain at nociceptors of the paravascular tissue and veins in humans. J Physiol. 1995;487:253-258.
30. Holthusen H. Involvement of the NO/cyclic GMP pathway in bradykinin-evoked pain from veins in humans. Pain. 1997;69:87-92.
31. Kindgen-Milles DW. Effects of prostaglandin E2 on the intensity of bradykinin-evoked pain from skin and veins of humans. Eur J Pharmacol. 1995;294:491-496.
32. Howlader MH, Smith PD. Increased plasma total nitric oxide among patients with severe chronic venous disease. Int Angiol. 2002;21:180-186.
33. Saharay M, Shields DA, Porter JB, Scurr JH, Coleridge Smith PD. Leukocyte activity in the microcirculation of the leg in patients with chronic venous disease. J Vasc Surg. 1997;26:265-273.
34. Howlader MH, Smith PD. Correlation of severity of chronic venous disease with capillary morphology assessed by capillary microscopy. J Vasc Surg. 2006;43:563-569.
35. Virgini-Magalhaes CE, Porto CL, Fernandes FF, Dorigo DM, Bottino DA, Bouskela E. Use of microcirculatory parameters to evaluate chronic venous insufficiency. J Vasc Surg. 2006;43:1037-1044.
36. Resnick N, Yahav H, Khachigian LM, el al. Endothelial gene regulation by laminar shear stress. Adv Exp Med Biol. 1997;430:155-164.
37. Shyy JY, Li YS, Lin MC, et al. Multiple cis-elements mediate shear stress-induced gene expression. J Biomech. 1995;28:1451-1457.
38. Chen KD, Li YS, Kim M, et al. Mechanotransduction in response to shear stress. Roles of receptor tyrosine kinases, integrins, and Shc. J Biol Chem. 1999;274:18393-183400.
39. Reinhardt F, Wetzel T, Vetten S, et al. Peripheral neuropathy in chronic venous insufficiency. Muscle Nerve. 2000;23:883-887.
40. Shami SK, Shields DA, Farrah J, Scurr JH, Coleridge Smith PD. Peripheral nerve function in chronic venous insufficiency. Eur J Vasc Surg. 1993;7:195-200.
41. Padberg FT, Jr., Maniker AH, Carmel G, Pappas PJ, Silva MB, Jr., Hobson RW, 2nd. Sensory impairment: a feature of chronic venous insufficiency. J Vasc Surg. 1999;30:836-842.
42. Zubieta JK, Heitzeg MM, Smith YR, et al. COMT val 158met genotype affects muopioid neurotransmitter responses to a pain stressor. Science. 2003;299:1240-1243.