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Volumn 68, Issue 14, 2008, Pages 1963-1973

Use of somatostatin analogues in obesity

Author keywords

Lanreotide, therapeutic use; Obesity; Octreotide, therapeutic use; Somatostatins, therapeutic use

Indexed keywords

ANGIOPEPTIN; GHRELIN; INSULIN; LONG ACTING DRUG; OCTREOTIDE; SOMATOSTATIN DERIVATIVE; SOMATOSTATIN RECEPTOR 5;

EID: 51449123652     PISSN: 00126667     EISSN: 00126667     Source Type: Journal    
DOI: 10.2165/00003495-200868140-00003     Document Type: Review
Times cited : (28)

References (83)
  • 1
    • 0031959781 scopus 로고    scopus 로고
    • The obesity epidemic is a worldwide phenomenon
    • Apr;
    • Popkin BM, Doak CM. The obesity epidemic is a worldwide phenomenon. Nutr Rev 1998 Apr; 56 (4 Pt 1): 106-14
    • (1998) Nutr Rev , vol.56 , Issue.4 PART 1 , pp. 106-114
    • Popkin, B.M.1    Doak, C.M.2
  • 2
    • 13444306683 scopus 로고    scopus 로고
    • Prevalence and trends of obesity in children and adults of South Europe
    • Aug;
    • Tzotzas T, Krassas GE. Prevalence and trends of obesity in children and adults of South Europe. Pediatr Endocrinol Rev 2004 Aug; 1 Suppl. 3: 448-54
    • (2004) Pediatr Endocrinol Rev , vol.1 , Issue.SUPPL. 3 , pp. 448-454
    • Tzotzas, T.1    Krassas, G.E.2
  • 3
    • 51449083912 scopus 로고    scopus 로고
    • Management of obesity: Pharmacotherapy
    • Kopelman Caterson LD, Dietz WH, editors, Malden MA, Blackwell
    • Atkinson RL. Management of obesity: pharmacotherapy. In: Kopelman PG, Caterson LD, Dietz WH, editors. Clinical obesity in adults and children. Malden (MA): Blackwell, 2005: 380-93
    • (2005) Clinical obesity in adults and children , pp. 380-393
    • Atkinson, R.L.1
  • 4
    • 33746806798 scopus 로고    scopus 로고
    • Investigational therapies in the treatment of obesity
    • Aug;
    • Mancini MC, Halpern A. Investigational therapies in the treatment of obesity. Expert Opin Investig Drugs 2006 Aug; 15 (8): 897-915
    • (2006) Expert Opin Investig Drugs , vol.15 , Issue.8 , pp. 897-915
    • Mancini, M.C.1    Halpern, A.2
  • 5
    • 0015914428 scopus 로고
    • Hypothalamic polypeptide that inhibits the secretion of immunoreactive pituitary growth hormone
    • Jan;
    • Brazeau P, Vale W, Burgus R, et al. Hypothalamic polypeptide that inhibits the secretion of immunoreactive pituitary growth hormone. Science 1973 Jan; 179 (68): 77-9
    • (1973) Science , vol.179 , Issue.68 , pp. 77-79
    • Brazeau, P.1    Vale, W.2    Burgus, R.3
  • 6
    • 0030612281 scopus 로고    scopus 로고
    • Molecular pharmacology of somatostatin receptor subtypes
    • Jun;
    • Patel YC. Molecular pharmacology of somatostatin receptor subtypes. J Endocrinol Invest 1997 Jun; 20 (6): 348-67
    • (1997) J Endocrinol Invest , vol.20 , Issue.6 , pp. 348-367
    • Patel, Y.C.1
  • 7
    • 0034465470 scopus 로고    scopus 로고
    • Somatostatin inhibits insulin and glucagon secretion via two receptors subtypes: An in vitro study of pancreatic islets from somatostatin receptor 2 knockout mice
    • Jan;
    • Strowski MZ, Parmar RM, Blake AD, et al. Somatostatin inhibits insulin and glucagon secretion via two receptors subtypes: an in vitro study of pancreatic islets from somatostatin receptor 2 knockout mice. Endocrinology 2000 Jan; 141 (1): 111-7
    • (2000) Endocrinology , vol.141 , Issue.1 , pp. 111-117
    • Strowski, M.Z.1    Parmar, R.M.2    Blake, A.D.3
  • 8
    • 0029114410 scopus 로고
    • Molecular biology of somatostatin receptors
    • Aug;
    • Reisine T, Bell GI. Molecular biology of somatostatin receptors. Endocr Rev 1995 Aug; 16 (4): 427-42
    • (1995) Endocr Rev , vol.16 , Issue.4 , pp. 427-442
    • Reisine, T.1    Bell, G.I.2
  • 9
    • 0038440483 scopus 로고    scopus 로고
    • A novel somatostatin mimic with broad somatotropin release inhibitory factor receptor binding and superior therapeutic potential
    • Jun;
    • Lewis I, Bauer W, Albert R, et al. A novel somatostatin mimic with broad somatotropin release inhibitory factor receptor binding and superior therapeutic potential. J Med Chem 2003 Jun; 46 (12): 2334-44
    • (2003) J Med Chem , vol.46 , Issue.12 , pp. 2334-2344
    • Lewis, I.1    Bauer, W.2    Albert, R.3
  • 11
    • 51449122845 scopus 로고    scopus 로고
    • The efficacy of somatostatin analogues in the treatment of diabetic retinopathy and thyroid eye disease
    • Krassas GE, Tzotzas T, Papazisis K, et al. The efficacy of somatostatin analogues in the treatment of diabetic retinopathy and thyroid eye disease. Clin Ophthalmol 2007; 1 (3): 209-15
    • (2007) Clin Ophthalmol , vol.1 , Issue.3 , pp. 209-215
    • Krassas, G.E.1    Tzotzas, T.2    Papazisis, K.3
  • 13
    • 33748080457 scopus 로고    scopus 로고
    • The effects of insulin on the central nervous system: Focus on appetite regulation
    • Jul;
    • Pliquett RU, Führer D, Falk S, et al. The effects of insulin on the central nervous system: focus on appetite regulation. Horm Metab Res 2006 Jul; 38 (7): 442-6
    • (2006) Horm Metab Res , vol.38 , Issue.7 , pp. 442-446
    • Pliquett, R.U.1    Führer, D.2    Falk, S.3
  • 14
    • 0037288941 scopus 로고    scopus 로고
    • Insulin and leptin revisited: Adiposity signals with overlapping physiological and intracellular signaling capabilities
    • Jan;
    • Niswender KD, Schwartz MW. Insulin and leptin revisited: adiposity signals with overlapping physiological and intracellular signaling capabilities. Front Neuroendocrinol 2003 Jan; 24 (1): 1-10
    • (2003) Front Neuroendocrinol , vol.24 , Issue.1 , pp. 1-10
    • Niswender, K.D.1    Schwartz, M.W.2
  • 15
    • 0029401988 scopus 로고
    • Insulin normalization as an approach to the pharmacological treatment of obesity
    • Nov;
    • Campfield LA, Smith FJ, Mackie G, et al. Insulin normalization as an approach to the pharmacological treatment of obesity. Obes Res 1995 Nov; 3 Suppl. 4: S591-603
    • (1995) Obes Res , vol.3 , Issue.SUPPL. 4
    • Campfield, L.A.1    Smith, F.J.2    Mackie, G.3
  • 16
    • 12244309064 scopus 로고    scopus 로고
    • Somatostatin receptor subtype 5 regulates insulin secretion and glucose homeostasis
    • Jan;
    • Strowski MZ, Kohler M, Chen HY, et al. Somatostatin receptor subtype 5 regulates insulin secretion and glucose homeostasis. Mol Endocrinol 2003 Jan; 17 (1): 93-106
    • (2003) Mol Endocrinol , vol.17 , Issue.1 , pp. 93-106
    • Strowski, M.Z.1    Kohler, M.2    Chen, H.Y.3
  • 17
    • 2942560866 scopus 로고    scopus 로고
    • Inhibition of insulin secretion as a new drug target in the treatment of metabolic disorders
    • Jun;
    • Hansen JB, Arkhammar PO, Bodvarsdottir TB, et al. Inhibition of insulin secretion as a new drug target in the treatment of metabolic disorders. Curr Med Chem 2004 Jun; 11 (12): 1595-615
    • (2004) Curr Med Chem , vol.11 , Issue.12 , pp. 1595-1615
    • Hansen, J.B.1    Arkhammar, P.O.2    Bodvarsdottir, T.B.3
  • 18
    • 10744228321 scopus 로고    scopus 로고
    • Octreotide therapy of pediatric hypothalamic obesity: A double-blind, placebo-controlled trial
    • Jun;
    • Lustig RH, Hinds PS, Ringwald-Smith K, et al. Octreotide therapy of pediatric hypothalamic obesity: a double-blind, placebo-controlled trial. J Clin Endocrinol Metab 2003 Jun; 88 (6): 2586-92
    • (2003) J Clin Endocrinol Metab , vol.88 , Issue.6 , pp. 2586-2592
    • Lustig, R.H.1    Hinds, P.S.2    Ringwald-Smith, K.3
  • 19
    • 32544456616 scopus 로고    scopus 로고
    • A multicenter, randomized, double-blind, placebo-controlled, dose-finding trial of a long-acting formulation of octreotide in promoting weight loss in obese adults with insulin hypersecretion
    • Feb;
    • Lustig RH, Greenway F, Velasquez-Mieyer P, et al. A multicenter, randomized, double-blind, placebo-controlled, dose-finding trial of a long-acting formulation of octreotide in promoting weight loss in obese adults with insulin hypersecretion. Int J Obes (Lond) 2006 Feb; 30 (2): 331-41
    • (2006) Int J Obes (Lond) , vol.30 , Issue.2 , pp. 331-341
    • Lustig, R.H.1    Greenway, F.2    Velasquez-Mieyer, P.3
  • 20
    • 0036595257 scopus 로고    scopus 로고
    • Use of somatostatin receptor ligands in obesity and diabetic complications
    • Jun;
    • Boehm BO, Lustig RH. Use of somatostatin receptor ligands in obesity and diabetic complications. Best Pract Res Clin Gastroenterol 2002 Jun; 16 (3): 493-509
    • (2002) Best Pract Res Clin Gastroenterol , vol.16 , Issue.3 , pp. 493-509
    • Boehm, B.O.1    Lustig, R.H.2
  • 21
    • 33750041947 scopus 로고    scopus 로고
    • Molecular mechanisms of insulin resistance and associated diseases
    • Jan;
    • Mlinar B, Marc J, Janez A, et al. Molecular mechanisms of insulin resistance and associated diseases. Clin Chim Acta 2007 Jan; 375 (1-2): 20-35
    • (2007) Clin Chim Acta , vol.375 , Issue.1-2 , pp. 20-35
    • Mlinar, B.1    Marc, J.2    Janez, A.3
  • 22
    • 0021906772 scopus 로고
    • Production of insulin resistance by hyperinsulinaemia in man
    • Feb;
    • Rizza RA, Mandarino LJ, Genest J, et al. Production of insulin resistance by hyperinsulinaemia in man. Diabetologia 1985 Feb; 28 (2): 70-5
    • (1985) Diabetologia , vol.28 , Issue.2 , pp. 70-75
    • Rizza, R.A.1    Mandarino, L.J.2    Genest, J.3
  • 23
    • 0031005528 scopus 로고    scopus 로고
    • Acute postchallenge hyperinsulinemia predicts weight gain: A prospective study
    • Jun;
    • Sigal RJ, El-Hashimy M, Martin BC, et al. Acute postchallenge hyperinsulinemia predicts weight gain: a prospective study. Diabetes 1997 Jun; 46 (6): 1025-9
    • (1997) Diabetes , vol.46 , Issue.6 , pp. 1025-1029
    • Sigal, R.J.1    El-Hashimy, M.2    Martin, B.C.3
  • 24
    • 0028213750 scopus 로고
    • Early changes in postprandial insulin secretion, not in insulin sensitivity, characterize juvenile obesity
    • May;
    • Le Stunff C, Bougneres P. Early changes in postprandial insulin secretion, not in insulin sensitivity, characterize juvenile obesity. Diabetes 1994 May; 43 (5): 696-702
    • (1994) Diabetes , vol.43 , Issue.5 , pp. 696-702
    • Le Stunff, C.1    Bougneres, P.2
  • 25
    • 0021360635 scopus 로고
    • The antilipolytic action of insulin in obese subjects with resistance to its glucoregulatory action
    • Mar;
    • Howard BV, Klimes I, Vasquez B, et al. The antilipolytic action of insulin in obese subjects with resistance to its glucoregulatory action. J Clin Endocrinol Metab 1984 Mar; 58 (3): 544-8
    • (1984) J Clin Endocrinol Metab , vol.58 , Issue.3 , pp. 544-548
    • Howard, B.V.1    Klimes, I.2    Vasquez, B.3
  • 26
    • 0017681635 scopus 로고
    • Dose response to insulin in man: Differential effects on glucose and ketone body regulation
    • Jun;
    • Schade DS, Eaton RP. Dose response to insulin in man: differential effects on glucose and ketone body regulation. J Clin Endocrinol Metab 1977 Jun; 44 (6): 1038-53
    • (1977) J Clin Endocrinol Metab , vol.44 , Issue.6 , pp. 1038-1053
    • Schade, D.S.1    Eaton, R.P.2
  • 28
    • 15544362925 scopus 로고    scopus 로고
    • The gut and energy balance: Visceral allies in the obesity wars
    • Mar;
    • Badman MK, Flier JS. The gut and energy balance: visceral allies in the obesity wars. Science 2005 Mar; 307 (5717): 1909-14
    • (2005) Science , vol.307 , Issue.5717 , pp. 1909-1914
    • Badman, M.K.1    Flier, J.S.2
  • 29
    • 0036329037 scopus 로고    scopus 로고
    • Hypothalamic obesity in humans: What do we know and what can be done?
    • Feb;
    • Pinkney J, Wilding J, Williams G, et al. Hypothalamic obesity in humans: what do we know and what can be done? Obes Rev 2002 Feb; 3 (1): 27-34
    • (2002) Obes Rev , vol.3 , Issue.1 , pp. 27-34
    • Pinkney, J.1    Wilding, J.2    Williams, G.3
  • 30
    • 0018617346 scopus 로고
    • An autonomic hypothesis for hypothalamic obesity
    • Aug;
    • Inoue S, Bray GA. An autonomic hypothesis for hypothalamic obesity. Life Sci 1979 Aug; 25 (7): 561-6
    • (1979) Life Sci , vol.25 , Issue.7 , pp. 561-566
    • Inoue, S.1    Bray, G.A.2
  • 31
    • 0031623306 scopus 로고    scopus 로고
    • The MONA LISA hypothesis in the time of leptin
    • Bray GA, York DA. The MONA LISA hypothesis in the time of leptin. Recent Prog Horm Res 1998; 53: 95-117
    • (1998) Recent Prog Horm Res , vol.53 , pp. 95-117
    • Bray, G.A.1    York, D.A.2
  • 32
    • 0020332463 scopus 로고
    • The role of vagally-medicated hyperinsulinemia in hypothalamic obesity
    • King BM, Frohman LA. The role of vagally-medicated hyperinsulinemia in hypothalamic obesity. Neurosci Biobehav Rev 1982; 6 (2): 205-14
    • (1982) Neurosci Biobehav Rev , vol.6 , Issue.2 , pp. 205-214
    • King, B.M.1    Frohman, L.A.2
  • 33
    • 0035170022 scopus 로고    scopus 로고
    • Peptide-binding G protein-coupled receptors: New opportunities for drug design
    • Nov;
    • Gurrath M. Peptide-binding G protein-coupled receptors: new opportunities for drug design. Curr Med Chem 2001 Nov; 8 (13): 1605-48
    • (2001) Curr Med Chem , vol.8 , Issue.13 , pp. 1605-1648
    • Gurrath, M.1
  • 35
    • 0031984040 scopus 로고    scopus 로고
    • Dose-dependent effect of octreotide on insulin secretion after OGTT in obesity
    • Bertoli A, Magnaterra R, Borboni P, et al. Dose-dependent effect of octreotide on insulin secretion after OGTT in obesity. Horm Res 1998; 49 (1): 17-21
    • (1998) Horm Res , vol.49 , Issue.1 , pp. 17-21
    • Bertoli, A.1    Magnaterra, R.2    Borboni, P.3
  • 36
    • 0028625632 scopus 로고
    • Acute effects of octreotide, a long-acting somatostatin analogue, on the insulinemic and glycemic responses to a mixed meal in patients with essential obesity: A dose-response study
    • Giustina A, Bussi AR, Pizzocolo G, et al. Acute effects of octreotide, a long-acting somatostatin analogue, on the insulinemic and glycemic responses to a mixed meal in patients with essential obesity: a dose-response study. Diabetes Nutr Metab 1994; 7: 735-41
    • (1994) Diabetes Nutr Metab , vol.7 , pp. 735-741
    • Giustina, A.1    Bussi, A.R.2    Pizzocolo, G.3
  • 37
    • 0025783499 scopus 로고
    • Long-term treatment of 189 acromegalic patients with the somatostatin analog octreotide: Results of the International Multicenter Acromegaly Study Group
    • Aug;
    • Vance ML, Harris AG. Long-term treatment of 189 acromegalic patients with the somatostatin analog octreotide: results of the International Multicenter Acromegaly Study Group. Arch Intern Med 1991 Aug; 151 (8): 1573-8
    • (1991) Arch Intern Med , vol.151 , Issue.8 , pp. 1573-1578
    • Vance, M.L.1    Harris, A.G.2
  • 38
    • 0028285739 scopus 로고
    • Effect of octreotide on glucose tolerance in acromegaly
    • Jun;
    • Koop BL, Harris AG, Ezzat S. Effect of octreotide on glucose tolerance in acromegaly. Eur J Endocrinol 1994 Jun; 130 (6): 581-6
    • (1994) Eur J Endocrinol , vol.130 , Issue.6 , pp. 581-586
    • Koop, B.L.1    Harris, A.G.2    Ezzat, S.3
  • 39
    • 10744228519 scopus 로고    scopus 로고
    • Glucose homeostasis in acromegaly: Effects of long-acting somatostatin analogues treatment
    • Oct;
    • Baldelli R, Battista C, Leonetti F, et al. Glucose homeostasis in acromegaly: effects of long-acting somatostatin analogues treatment. Clin Endocrinol (Oxf) 2003 Oct; 59 (4): 492-9
    • (2003) Clin Endocrinol (Oxf) , vol.59 , Issue.4 , pp. 492-499
    • Baldelli, R.1    Battista, C.2    Leonetti, F.3
  • 40
    • 0030744939 scopus 로고    scopus 로고
    • Divergent effects of octreotide on glucose tolerance in patients with acromegaly
    • May;
    • Hizuka N. Divergent effects of octreotide on glucose tolerance in patients with acromegaly. Intern Med 1997 May; 36 (5): 319-20
    • (1997) Intern Med , vol.36 , Issue.5 , pp. 319-320
    • Hizuka, N.1
  • 41
    • 0023628230 scopus 로고
    • Clinical and pathophysiological aspects of somatostatin and the gastrointestinal tract
    • Lamers CB. Clinical and pathophysiological aspects of somatostatin and the gastrointestinal tract. Acta Endocrinol Suppl (Copenh) 1987; 286: 19-25
    • (1987) Acta Endocrinol Suppl (Copenh) , vol.286 , pp. 19-25
    • Lamers, C.B.1
  • 42
    • 0030911816 scopus 로고    scopus 로고
    • Octreotide long-acting release (LAR): A review of its pharmacological properties and therapeutic use in the management of acromegaly
    • Gillis JC, Noble S, Goa KL. Octreotide long-acting release (LAR): a review of its pharmacological properties and therapeutic use in the management of acromegaly. Drugs 1997; 53 (4): 681-99
    • (1997) Drugs , vol.53 , Issue.4 , pp. 681-699
    • Gillis, J.C.1    Noble, S.2    Goa, K.L.3
  • 43
    • 0038030760 scopus 로고    scopus 로고
    • Ghrelin secretion in humans is sexually dimorphic, suppressed by somatostatin, and not affected by the ambient growth hormone levels
    • May;
    • Barkan AL, Dimaraki EV, Jessup SK, et al. Ghrelin secretion in humans is sexually dimorphic, suppressed by somatostatin, and not affected by the ambient growth hormone levels. J Clin Endocrinol Metab 2003 May; 88 (5): 2180-4
    • (2003) J Clin Endocrinol Metab , vol.88 , Issue.5 , pp. 2180-2184
    • Barkan, A.L.1    Dimaraki, E.V.2    Jessup, S.K.3
  • 44
    • 0242361163 scopus 로고    scopus 로고
    • Effect of a somatostatin analogue on gastric motor and sensory functions in healthy humans
    • Nov;
    • Foxx-Orenstein A, Camilleri M, Stephens D, et al. Effect of a somatostatin analogue on gastric motor and sensory functions in healthy humans. Gut 2003 Nov; 52 (11): 1555-61
    • (2003) Gut , vol.52 , Issue.11 , pp. 1555-1561
    • Foxx-Orenstein, A.1    Camilleri, M.2    Stephens, D.3
  • 45
    • 33644664655 scopus 로고    scopus 로고
    • Effect of somatostatin analog on postprandial satiation in obesity
    • Sep;
    • Cremonini F, Camilleri M, Gonenne J, et al. Effect of somatostatin analog on postprandial satiation in obesity. Obes Res 2005 Sep; 13 (9): 1572-9
    • (2005) Obes Res , vol.13 , Issue.9 , pp. 1572-1579
    • Cremonini, F.1    Camilleri, M.2    Gonenne, J.3
  • 46
    • 0019555254 scopus 로고
    • Somatostatin decreases food intake of rats and baboons
    • Apr;
    • Lotter EC, Krinsky R, McKay JM, et al. Somatostatin decreases food intake of rats and baboons. J Comp Physiol Psychol 1981 Apr; 95 (2): 278-87
    • (1981) J Comp Physiol Psychol , vol.95 , Issue.2 , pp. 278-287
    • Lotter, E.C.1    Krinsky, R.2    McKay, J.M.3
  • 47
    • 0019956085 scopus 로고
    • Peripherally administered somatostatin reduces feeding by a vagal mediated mechanism
    • Jun;
    • Levine AS, Morley JE. Peripherally administered somatostatin reduces feeding by a vagal mediated mechanism. Pharmacol Biochem Behav 1982 Jun; 16 (6): 897-902
    • (1982) Pharmacol Biochem Behav , vol.16 , Issue.6 , pp. 897-902
    • Levine, A.S.1    Morley, J.E.2
  • 48
    • 0024241716 scopus 로고
    • Inhibition of growth hormone-stimulated lipolysis by somatostatin, insulin, and insulin-like growth factors (somatomedins) in vitro
    • Dec;
    • Campbell RM, Scanes CG. Inhibition of growth hormone-stimulated lipolysis by somatostatin, insulin, and insulin-like growth factors (somatomedins) in vitro. Proc Soc Exp Biol Med 1988 Dec; 189 (3): 362-6
    • (1988) Proc Soc Exp Biol Med , vol.189 , Issue.3 , pp. 362-366
    • Campbell, R.M.1    Scanes, C.G.2
  • 49
    • 0016836094 scopus 로고
    • Manifestations of hypothalamic obesity in man: A comprehensive investigation of eight patients and a review of the literature
    • Jul;
    • Bray GA, Gallagher TF. Manifestations of hypothalamic obesity in man: a comprehensive investigation of eight patients and a review of the literature. Medicine 1975 Jul; 54 (4): 301-30
    • (1975) Medicine , vol.54 , Issue.4 , pp. 301-330
    • Bray, G.A.1    Gallagher, T.F.2
  • 51
    • 0031707099 scopus 로고    scopus 로고
    • The descriptive epidemiology of craniopharyngioma
    • Oct;
    • Bunin GR, Surawicz TS, Witman PA, et al. The descriptive epidemiology of craniopharyngioma. J Neurosurg 1998 Oct; 89 (4): 547-51
    • (1998) J Neurosurg , vol.89 , Issue.4 , pp. 547-551
    • Bunin, G.R.1    Surawicz, T.S.2    Witman, P.A.3
  • 52
    • 3242673114 scopus 로고    scopus 로고
    • Longitudinal study on growth and body mass index before and after diagnosis of childhood craniopharyngioma
    • Jul;
    • Muller HL, Emser A, Faldum A, et al. Longitudinal study on growth and body mass index before and after diagnosis of childhood craniopharyngioma. J Clin Endocrinol Metab 2004 Jul; 89 (7): 3298-305
    • (2004) J Clin Endocrinol Metab , vol.89 , Issue.7 , pp. 3298-3305
    • Muller, H.L.1    Emser, A.2    Faldum, A.3
  • 53
    • 33644775540 scopus 로고    scopus 로고
    • Weight gain in craniopharyngioma: A model for hypothalamic obesity
    • Feb;
    • Ahmet A, Blaser S, Stephens D, et al. Weight gain in craniopharyngioma: a model for hypothalamic obesity. J Pediatr Endocrinol Metab 2006 Feb; 19 (2): 121-7
    • (2006) J Pediatr Endocrinol Metab , vol.19 , Issue.2 , pp. 121-127
    • Ahmet, A.1    Blaser, S.2    Stephens, D.3
  • 54
    • 33746144396 scopus 로고    scopus 로고
    • Genetics of human obesity
    • Aug;
    • Clement K. Genetics of human obesity. C R Biol 2006 Aug; 329 (8): 608-22
    • (2006) C R Biol , vol.329 , Issue.8 , pp. 608-622
    • Clement, K.1
  • 55
    • 33746288477 scopus 로고    scopus 로고
    • The hypothalamus, hormones, and hunger: Alterations in human obesity and illness
    • Goldstone AP. The hypothalamus, hormones, and hunger: alterations in human obesity and illness. Prog Brain Res 2006; 153: 57-73
    • (2006) Prog Brain Res , vol.153 , pp. 57-73
    • Goldstone, A.P.1
  • 56
    • 33646404622 scopus 로고    scopus 로고
    • Melanocortin 4 receptor mutations in a large cohort of severely obese adults: Prevalence, functional classification, genotype-phenotype relationship, and lack of association with binge eating
    • May;
    • Zhang S, Bertrais S, Hercberg S, et al. Melanocortin 4 receptor mutations in a large cohort of severely obese adults: prevalence, functional classification, genotype-phenotype relationship, and lack of association with binge eating. J Clin Endocrinol Metab 2006 May; 91 (5): 1811-8
    • (2006) J Clin Endocrinol Metab , vol.91 , Issue.5 , pp. 1811-1818
    • Zhang, S.1    Bertrais, S.2    Hercberg, S.3
  • 57
    • 33646240044 scopus 로고    scopus 로고
    • Obesity in childhood cancer survivors
    • Apr;
    • Lustig RH. Obesity in childhood cancer survivors. Pediatr Endocrinol Rev 2006 Apr; 3 Suppl. 2: 306-11
    • (2006) Pediatr Endocrinol Rev , vol.3 , Issue.SUPPL. 2 , pp. 306-311
    • Lustig, R.H.1
  • 59
    • 16344384203 scopus 로고    scopus 로고
    • Racial and etiopathologic dichotomies in insulin hypersecretion and resistance in obese children
    • Apr;
    • Preeyasombat C, Bacchetti P, Lazar AA, et al. Racial and etiopathologic dichotomies in insulin hypersecretion and resistance in obese children. J Pediatr 2005 Apr; 146 (4): 474-81
    • (2005) J Pediatr , vol.146 , Issue.4 , pp. 474-481
    • Preeyasombat, C.1    Bacchetti, P.2    Lazar, A.A.3
  • 60
    • 35948962283 scopus 로고    scopus 로고
    • Impact sibutramine therapy in children with hypothalamic obesity or obesity with aggravating syndromes
    • Nov;
    • Danielsson P, Janson A, Norgren S, et al. Impact sibutramine therapy in children with hypothalamic obesity or obesity with aggravating syndromes. J Clin Endocrinol Metab 2007 Nov; 92 (11): 4101-6
    • (2007) J Clin Endocrinol Metab , vol.92 , Issue.11 , pp. 4101-4106
    • Danielsson, P.1    Janson, A.2    Norgren, S.3
  • 61
    • 0037656509 scopus 로고    scopus 로고
    • Growth hormone treatment improves body composition in adults with Prader-Willi syndrome
    • May;
    • Hoybye C, Hilding A, Jacobsson H, et al. Growth hormone treatment improves body composition in adults with Prader-Willi syndrome. Clin Endocrinol (Oxf) 2003 May; 58 (5): 653-61
    • (2003) Clin Endocrinol (Oxf) , vol.58 , Issue.5 , pp. 653-661
    • Hoybye, C.1    Hilding, A.2    Jacobsson, H.3
  • 62
    • 8744262948 scopus 로고    scopus 로고
    • Changes in height, weight, and body mass index in children with craniopharyngioma after three years of growth hormone therapy: Analysis of KIGS (Pfizer International Growth Database)
    • Nov;
    • Geffner M, Lundberg M, Koltowska-Haggstrom M, et al. Changes in height, weight, and body mass index in children with craniopharyngioma after three years of growth hormone therapy: analysis of KIGS (Pfizer International Growth Database). J Clin Endocrinol Metab 2004 Nov; 89 (11): 5435-40
    • (2004) J Clin Endocrinol Metab , vol.89 , Issue.11 , pp. 5435-5440
    • Geffner, M.1    Lundberg, M.2    Koltowska-Haggstrom, M.3
  • 63
    • 0021101029 scopus 로고
    • Truncal vagotomy in hypothalamic obesity
    • Jun;
    • Smith DK, Sarfeh J, Howard L. Truncal vagotomy in hypothalamic obesity. Lancet 1983 Jun; I (8337): 1330-1
    • (1983) Lancet , vol.1 , Issue.8337 , pp. 1330-1331
    • Smith, D.K.1    Sarfeh, J.2    Howard, L.3
  • 64
    • 0027174697 scopus 로고
    • Operations that are questionable for control of obesity
    • May;
    • Fobi MA. Operations that are questionable for control of obesity. Obes Surg 1993 May; 3 (2): 197-200
    • (1993) Obes Surg , vol.3 , Issue.2 , pp. 197-200
    • Fobi, M.A.1
  • 65
    • 0033497369 scopus 로고    scopus 로고
    • Hypothalamic obesity caused by cranial insult in children: Altered glucose and insulin dynamics and reversal by a somatostatin agonist
    • Aug;
    • Lustig RH, Rose SR, Burghen GA, et al. Hypothalamic obesity caused by cranial insult in children: altered glucose and insulin dynamics and reversal by a somatostatin agonist. J Pediatr 1999 Aug; 135 (2 Pt 1): 162-8
    • (1999) J Pediatr , vol.135 , Issue.2 PART 1 , pp. 162-168
    • Lustig, R.H.1    Rose, S.R.2    Burghen, G.A.3
  • 66
    • 0032076307 scopus 로고    scopus 로고
    • Imprinting in Prader-Willi and Angelman syndromes
    • May;
    • Nicholls RD, Saitoh S, Horsthemke B. Imprinting in Prader-Willi and Angelman syndromes. Trends Genet 1998 May; 14 (5): 194-200
    • (1998) Trends Genet , vol.14 , Issue.5 , pp. 194-200
    • Nicholls, R.D.1    Saitoh, S.2    Horsthemke, B.3
  • 67
    • 0027237285 scopus 로고
    • Measurement of excessive appetite and metabolic changes in Prader-Willi syndrome
    • Sep;
    • Holland AJ, Treasure J, Coskeran P, et al. Measurement of excessive appetite and metabolic changes in Prader-Willi syndrome. Int J Obes Relat Metab Disord 1993 Sep; 17 (9): 527-32
    • (1993) Int J Obes Relat Metab Disord , vol.17 , Issue.9 , pp. 527-532
    • Holland, A.J.1    Treasure, J.2    Coskeran, P.3
  • 68
    • 0036061558 scopus 로고    scopus 로고
    • Elevated plasma ghrelin levels in Prader Willi syndrome
    • Jul;
    • Cummings DE, Clement K, Purnell JQ, et al. Elevated plasma ghrelin levels in Prader Willi syndrome. Nat Med 2002 Jul; 8 (7): 643-4
    • (2002) Nat Med , vol.8 , Issue.7 , pp. 643-644
    • Cummings, D.E.1    Clement, K.2    Purnell, J.Q.3
  • 69
    • 0036399151 scopus 로고    scopus 로고
    • Ghrelin immunoreactivity in human plasma is suppressed by somatostatin
    • Oct;
    • Norrelund H, Hansen TK, Orskov H, et al. Ghrelin immunoreactivity in human plasma is suppressed by somatostatin. Clin Endocrinol (Oxf) 2002 Oct; 57 (4): 539-46
    • (2002) Clin Endocrinol (Oxf) , vol.57 , Issue.4 , pp. 539-546
    • Norrelund, H.1    Hansen, T.K.2    Orskov, H.3
  • 70
    • 21344474829 scopus 로고    scopus 로고
    • Regulation of ghrelin secretion by somatostatin analogs in rats
    • Jun;
    • Silva AP, Bethmann K, Raulf F, et al. Regulation of ghrelin secretion by somatostatin analogs in rats. Eur J Endocrinol 2005 Jun; 152 (6): 887-94
    • (2005) Eur J Endocrinol , vol.152 , Issue.6 , pp. 887-894
    • Silva, A.P.1    Bethmann, K.2    Raulf, F.3
  • 71
    • 0042885664 scopus 로고    scopus 로고
    • Circulating ghrelin levels are suppressed by meals and octreotide therapy in children with Prader-Willi syndrome
    • Aug;
    • Haqq AM, Stadler DD, Rosenfeld RG, et al. Circulating ghrelin levels are suppressed by meals and octreotide therapy in children with Prader-Willi syndrome. J Clin Endocrinol Metab 2003 Aug; 88 (8): 3573-6
    • (2003) J Clin Endocrinol Metab , vol.88 , Issue.8 , pp. 3573-3576
    • Haqq, A.M.1    Stadler, D.D.2    Rosenfeld, R.G.3
  • 72
    • 4043096513 scopus 로고    scopus 로고
    • Somatostatin infusion lowers plasma ghrelin without reducing appetite in adults with Prader-Willi syndrome
    • Aug;
    • Tan TM, Vanderpump M, Khoo B, et al. Somatostatin infusion lowers plasma ghrelin without reducing appetite in adults with Prader-Willi syndrome. J Clin Endocr Metabol 2004 Aug; 89 (8): 4162-5
    • (2004) J Clin Endocr Metabol , vol.89 , Issue.8 , pp. 4162-4165
    • Tan, T.M.1    Vanderpump, M.2    Khoo, B.3
  • 73
    • 17944374136 scopus 로고    scopus 로고
    • Visceral adipose tissue and metabolic complications of obesity are reduced in Prader-Willi syndrome female adults: Evidence for novel influences on body fat distribution
    • Sep;
    • Goldstone AP, Thomas EL, Brynes AE, et al. Visceral adipose tissue and metabolic complications of obesity are reduced in Prader-Willi syndrome female adults: evidence for novel influences on body fat distribution. J Clin Endocrinol Metab 2001 Sep; 86 (9): 4330-8
    • (2001) J Clin Endocrinol Metab , vol.86 , Issue.9 , pp. 4330-4338
    • Goldstone, A.P.1    Thomas, E.L.2    Brynes, A.E.3
  • 74
    • 32544449194 scopus 로고    scopus 로고
    • Circulating adiponectin levels, body composition and obesity-related variables in Prader-Willi syndrome: Comparison with obese subjects
    • Feb;
    • Kennedy L, Bittel DC, Kibiryeva N, et al. Circulating adiponectin levels, body composition and obesity-related variables in Prader-Willi syndrome: comparison with obese subjects. Int J Obes Relat Metab Disord 2006 Feb; 30 (2): 382-7
    • (2006) Int J Obes Relat Metab Disord , vol.30 , Issue.2 , pp. 382-387
    • Kennedy, L.1    Bittel, D.C.2    Kibiryeva, N.3
  • 75
    • 18844416580 scopus 로고    scopus 로고
    • Fasting and postprandial hyperghrelinemia in Prader-Willi syndrome is partially explained by hypoinsulinemia, and is not due to peptide YY3-36 deficiency or seen in hypothalamic obesity due to craniopharyngioma
    • May;
    • Goldstone AP, Patterson M, Kalingag N, et al. Fasting and postprandial hyperghrelinemia in Prader-Willi syndrome is partially explained by hypoinsulinemia, and is not due to peptide YY3-36 deficiency or seen in hypothalamic obesity due to craniopharyngioma. J Clin Endocrinol Metab 2005 May; 90 (5): 2681-90
    • (2005) J Clin Endocrinol Metab , vol.90 , Issue.5 , pp. 2681-2690
    • Goldstone, A.P.1    Patterson, M.2    Kalingag, N.3
  • 76
    • 33846887849 scopus 로고    scopus 로고
    • Holsen LM, Zarcone JR, Brooks WM, et al. Neural mechanisms underlying hyperphagia in Prader-Willi syndrome. Obesity (Silver Spring) 2006 Jun; 14 (6): 1028-37
    • Holsen LM, Zarcone JR, Brooks WM, et al. Neural mechanisms underlying hyperphagia in Prader-Willi syndrome. Obesity (Silver Spring) 2006 Jun; 14 (6): 1028-37
  • 77
    • 32544442895 scopus 로고    scopus 로고
    • Neural representations of hunger and satiety in Prader-Willi syndrome
    • Feb;
    • Hinton EC, Holland AJ, Gellatly MS, et al. Neural representations of hunger and satiety in Prader-Willi syndrome. Int J Obes (Lond) 2006 Feb; 30 (2): 313-21
    • (2006) Int J Obes (Lond) , vol.30 , Issue.2 , pp. 313-321
    • Hinton, E.C.1    Holland, A.J.2    Gellatly, M.S.3
  • 78
    • 0013102988 scopus 로고    scopus 로고
    • Suppression of insulin secretion is associated with weight loss and altered macronutrient intake and preference in a subset of obese adults
    • Feb;
    • Velasquez-Mieyer PA, Cowan PA, Arheart KL, et al. Suppression of insulin secretion is associated with weight loss and altered macronutrient intake and preference in a subset of obese adults. Int J Obes Relat Metab Disord 2003 Feb; 27 (2): 219-26
    • (2003) Int J Obes Relat Metab Disord , vol.27 , Issue.2 , pp. 219-226
    • Velasquez-Mieyer, P.A.1    Cowan, P.A.2    Arheart, K.L.3
  • 79
    • 1242284364 scopus 로고    scopus 로고
    • Race affects insulin and GLP-1 secretion and response to a long-acting somatostatin analogue in obese adults
    • Feb;
    • Velasquez-Mieyer PA, Umpierrez GE, Lustig RH, et al. Race affects insulin and GLP-1 secretion and response to a long-acting somatostatin analogue in obese adults. Int J Obes Relat Metab Disord 2004 Feb; 28 (2): 330-3
    • (2004) Int J Obes Relat Metab Disord , vol.28 , Issue.2 , pp. 330-333
    • Velasquez-Mieyer, P.A.1    Umpierrez, G.E.2    Lustig, R.H.3
  • 80
    • 0026705115 scopus 로고
    • Effects of the somatostatin analogue, octreotide, in polycystic ovary syndrome
    • Sep;
    • Prelevic GM, Wurzburger MI, Balint-Peric L, et al. Effects of the somatostatin analogue, octreotide, in polycystic ovary syndrome. Metabolism 1992 Sep; 41 Suppl. 2: 76-9
    • (1992) Metabolism , vol.41 , Issue.SUPPL. 2 , pp. 76-79
    • Prelevic, G.M.1    Wurzburger, M.I.2    Balint-Peric, L.3
  • 81
    • 23044445736 scopus 로고    scopus 로고
    • Efficacy of octreotide-LAR in dieting women with abdominal obesity and polycystic ovary syndrome
    • Jul;
    • Gambineri A, Patton L, De Iasio R, et al. Efficacy of octreotide-LAR in dieting women with abdominal obesity and polycystic ovary syndrome. J Clin Endocrinol Metab 2005 Jul; 90 (7): 3854-62
    • (2005) J Clin Endocrinol Metab , vol.90 , Issue.7 , pp. 3854-3862
    • Gambineri, A.1    Patton, L.2    De Iasio, R.3
  • 82
    • 33745219707 scopus 로고    scopus 로고
    • Insulin-sensitizing agents in polycystic ovary syndrome
    • Jul;
    • Pasquali R, Gambineri A. Insulin-sensitizing agents in polycystic ovary syndrome. Eur J Endocrinol 2006 Jul; 86 Suppl. 1: S28-9
    • (2006) Eur J Endocrinol , vol.86 , Issue.SUPPL. 1
    • Pasquali, R.1    Gambineri, A.2
  • 83
    • 30744443527 scopus 로고    scopus 로고
    • Insulin dynamics predict body mass index and z-score response to insulin suppression or sensitization pharmacotherapy in obese children
    • Jan;
    • Lustig RH, Mietus-Snyder ML, Bacchetti P, et al. Insulin dynamics predict body mass index and z-score response to insulin suppression or sensitization pharmacotherapy in obese children. J Pediatr 2006 Jan; 148 (1): 23-9
    • (2006) J Pediatr , vol.148 , Issue.1 , pp. 23-29
    • Lustig, R.H.1    Mietus-Snyder, M.L.2    Bacchetti, P.3


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