메뉴 건너뛰기




Volumn 78, Issue 4 SUPPL., 2008, Pages

Male contraception: what is on the horizon?

Author keywords

Hormonal approach; Male contraception; Sperm specific nonhormonal targets; Spermatogenesis

Indexed keywords

11BETA METHYL 19 NORTESTOSTERONE; 2 ETHYL 2,3,4,4A,5,9B HEXAHYDRO 8 IODO 7 METHYL 5 [4 CARBOMETHOXYPHENYL] 1H INDENO[1,2 C]PYRIDINE; ACYLINE; ADJUDIN; ANDROGEN; CONTRACEPTIVE AGENT; DIMETHANDROLONE; DIMETHANDROLONE UNDECANOATE; FOLLITROPIN; GAMENDAZOLE; GESTAGEN; GONADORELIN ANTAGONIST; GONADOTROPIN; LONIDAMINE; LUTEINIZING HORMONE; METHYLTESTOSTERONE; PYRIDINE DERIVATIVE; RTI 4587073; SELECTIVE ANDROGEN RECEPTOR MODULATOR; TESTOSTERONE; TESTOSTERONE UNDECANOATE; TRESTOLONE; UNCLASSIFIED DRUG;

EID: 51449098819     PISSN: 00107824     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.contraception.2008.03.018     Document Type: Article
Times cited : (17)

References (35)
  • 2
    • 38149009594 scopus 로고    scopus 로고
    • Reducing unintended pregnancy in the United States
    • Trussell J., and Wynn L.L. Reducing unintended pregnancy in the United States. Contraception 77 (2008) 1-5
    • (2008) Contraception , vol.77 , pp. 1-5
    • Trussell, J.1    Wynn, L.L.2
  • 3
    • 14044262293 scopus 로고    scopus 로고
    • Attitudes toward male fertility control: results of a multinational survey on four continents
    • Heinemann K., Saad F., Wiesemes M., White S., and Heinemann L. Attitudes toward male fertility control: results of a multinational survey on four continents. Hum Reprod 20 (2005) 549-556
    • (2005) Hum Reprod , vol.20 , pp. 549-556
    • Heinemann, K.1    Saad, F.2    Wiesemes, M.3    White, S.4    Heinemann, L.5
  • 4
    • 1642364780 scopus 로고    scopus 로고
    • Nass S.J., and Strauss III J.F. (Eds), The National Academies Press, Washington, DC
    • In: Nass S.J., and Strauss III J.F. (Eds). New frontiers in contraceptive research: a blueprint for action (2004), The National Academies Press, Washington, DC
    • (2004) New frontiers in contraceptive research: a blueprint for action
  • 6
    • 33646178623 scopus 로고    scopus 로고
    • Hormonal approaches to male contraception: approaching reality
    • Wu F.C. Hormonal approaches to male contraception: approaching reality. Mol Cell Endocrinol 250 (2006) 2-7
    • (2006) Mol Cell Endocrinol , vol.250 , pp. 2-7
    • Wu, F.C.1
  • 8
    • 33745287880 scopus 로고    scopus 로고
    • Male hormonal contraception: concept proven, product in sight?
    • Matthiesson K.L., and McLachlan R.I. Male hormonal contraception: concept proven, product in sight?. Hum Reprod Update 12 (2006) 463-482
    • (2006) Hum Reprod Update , vol.12 , pp. 463-482
    • Matthiesson, K.L.1    McLachlan, R.I.2
  • 9
    • 7044246174 scopus 로고    scopus 로고
    • Intratesticular testosterone concentrations comparable with serum levels are not sufficient to maintain normal sperm production in men receiving a hormonal contraceptive regimen
    • Coviello A.D., Bremner W.J., Matsumoto A.M., et al. Intratesticular testosterone concentrations comparable with serum levels are not sufficient to maintain normal sperm production in men receiving a hormonal contraceptive regimen. J Androl 25 (2004) 931-938
    • (2004) J Androl , vol.25 , pp. 931-938
    • Coviello, A.D.1    Bremner, W.J.2    Matsumoto, A.M.3
  • 10
    • 10344247116 scopus 로고    scopus 로고
    • A single dose of the potent gonadotropin-releasing hormone antagonist acyline suppresses gonadotropins and testosterone for 2 weeks in healthy young men
    • Herbst K.L., Coviello A.D., Page S., Amory J.K., Anawalt B.D., and Bremner W.J. A single dose of the potent gonadotropin-releasing hormone antagonist acyline suppresses gonadotropins and testosterone for 2 weeks in healthy young men. J Clin Endocrinol Metab 89 (2004) 5959-5965
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 5959-5965
    • Herbst, K.L.1    Coviello, A.D.2    Page, S.3    Amory, J.K.4    Anawalt, B.D.5    Bremner, W.J.6
  • 11
    • 20244381101 scopus 로고    scopus 로고
    • Norethisterone enanthate plus testosterone undecanoate for male contraception: effects of various injection intervals on spermatogenesis, reproductive hormones, testis, and prostate
    • Meriggiola M.C., Costantino A., Saad F., et al. Norethisterone enanthate plus testosterone undecanoate for male contraception: effects of various injection intervals on spermatogenesis, reproductive hormones, testis, and prostate. J Clin Endocrinol Metab 90 (2005) 2005-2014
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 2005-2014
    • Meriggiola, M.C.1    Costantino, A.2    Saad, F.3
  • 12
    • 33847184616 scopus 로고    scopus 로고
    • Expanding the therapeutic use of androgens via selective androgen receptor modulators (SARMs)
    • Gao W., and Dalton J.T. Expanding the therapeutic use of androgens via selective androgen receptor modulators (SARMs). Drug Discov Today 12 (2007) 241-248
    • (2007) Drug Discov Today , vol.12 , pp. 241-248
    • Gao, W.1    Dalton, J.T.2
  • 13
    • 33646809681 scopus 로고    scopus 로고
    • Dimethandrolone undecanoate: a new potent orally active androgen with progestational activity
    • Attardi B.J., Hild S.A., and Reel J.R. Dimethandrolone undecanoate: a new potent orally active androgen with progestational activity. Endocrinology 147 (2006) 3016-3026
    • (2006) Endocrinology , vol.147 , pp. 3016-3026
    • Attardi, B.J.1    Hild, S.A.2    Reel, J.R.3
  • 14
    • 0038578277 scopus 로고    scopus 로고
    • Evidence for tissue selectivity of the synthetic androgen 7-alpha-methyl-19-nortestosterone in hypogonadal men
    • Anderson R.A., Wallace A.M., Sattar N., Kumar N., and Sundaram K. Evidence for tissue selectivity of the synthetic androgen 7-alpha-methyl-19-nortestosterone in hypogonadal men. J Clin Endocrinol Metab 88 (2003) 2784-2793
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2784-2793
    • Anderson, R.A.1    Wallace, A.M.2    Sattar, N.3    Kumar, N.4    Sundaram, K.5
  • 15
    • 4043164111 scopus 로고    scopus 로고
    • The A-type cyclins and the meiotic cell cycle in mammalian male germ cells
    • Wolgemuth D.J., Lele K.M., Jobanputra V., and Salazar G. The A-type cyclins and the meiotic cell cycle in mammalian male germ cells. Int J Androl 27 (2004) 192-199
    • (2004) Int J Androl , vol.27 , pp. 192-199
    • Wolgemuth, D.J.1    Lele, K.M.2    Jobanputra, V.3    Salazar, G.4
  • 16
    • 34547838930 scopus 로고    scopus 로고
    • Retinoid signaling during spermatogenesis as revealed by genetic and metabolic manipulations of retinoic acid receptor alpha
    • Wolgemuth D.J., and Chung S.S. Retinoid signaling during spermatogenesis as revealed by genetic and metabolic manipulations of retinoic acid receptor alpha. Soc Reprod Fertil Suppl 63 (2007) 11-23
    • (2007) Soc Reprod Fertil Suppl , vol.63 , pp. 11-23
    • Wolgemuth, D.J.1    Chung, S.S.2
  • 17
    • 33947415685 scopus 로고    scopus 로고
    • Development of l-CDB-4022 as a nonsteroidal male oral contraceptive: induction and recovery from severe oligospermia in the adult male cynomolgus monkey (Macaca fascicularis)
    • Hild S.A., Marshall G.R., Attardi B.J., et al. Development of l-CDB-4022 as a nonsteroidal male oral contraceptive: induction and recovery from severe oligospermia in the adult male cynomolgus monkey (Macaca fascicularis). Endocrinology 148 (2007) 1784-1796
    • (2007) Endocrinology , vol.148 , pp. 1784-1796
    • Hild, S.A.1    Marshall, G.R.2    Attardi, B.J.3
  • 18
    • 33750735046 scopus 로고    scopus 로고
    • A male contraceptive targeting germ cell adhesion
    • Mruk D.D., Wong C.H., Silvestrini B., and Cheng C.Y. A male contraceptive targeting germ cell adhesion. Nat Med 12 (2006) 1323-1328
    • (2006) Nat Med , vol.12 , pp. 1323-1328
    • Mruk, D.D.1    Wong, C.H.2    Silvestrini, B.3    Cheng, C.Y.4
  • 19
    • 44349123956 scopus 로고    scopus 로고
    • A novel potent indazole carboxylic acid derivative blocks spermatogenesis and is contraceptive in rats after a single oral dose
    • Tash J.S., Attardi B., Hild S.A., Chakrasali R., Jakkaraj S.R., and Georg G.I. A novel potent indazole carboxylic acid derivative blocks spermatogenesis and is contraceptive in rats after a single oral dose. Biol Reprod 78 (2008) 1127-1138
    • (2008) Biol Reprod , vol.78 , pp. 1127-1138
    • Tash, J.S.1    Attardi, B.2    Hild, S.A.3    Chakrasali, R.4    Jakkaraj, S.R.5    Georg, G.I.6
  • 20
    • 33846786558 scopus 로고    scopus 로고
    • Targeted and reversible disruption of the blood-testis barrier by an FSH mutant-occludin peptide conjugate
    • Wong C.H., Mruk D.D., Lee W.M., and Cheng C.Y. Targeted and reversible disruption of the blood-testis barrier by an FSH mutant-occludin peptide conjugate. FASEB J 21 (2007) 438-448
    • (2007) FASEB J , vol.21 , pp. 438-448
    • Wong, C.H.1    Mruk, D.D.2    Lee, W.M.3    Cheng, C.Y.4
  • 21
    • 33846613308 scopus 로고    scopus 로고
    • All four CatSper ion channel proteins are required for male fertility and sperm cell hyperactivated motility
    • Qi H., Moran M.M., and Navarro B. All four CatSper ion channel proteins are required for male fertility and sperm cell hyperactivated motility. Proc Natl Acad Sci U S A 104 (2007) 1219-1223
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 1219-1223
    • Qi, H.1    Moran, M.M.2    Navarro, B.3
  • 22
    • 34250624097 scopus 로고    scopus 로고
    • KSper, a pH-sensitive K+ current that controls sperm membrane potential
    • Navarro B., Kirichok Y., and Clapham D.E. KSper, a pH-sensitive K+ current that controls sperm membrane potential. Proc Natl Acad Sci U S A 104 (2007) 7688-7692
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 7688-7692
    • Navarro, B.1    Kirichok, Y.2    Clapham, D.E.3
  • 24
    • 31044449216 scopus 로고    scopus 로고
    • Postnatal expression of aquaporins in epithelial cells of the rat epididymis
    • Da Silva N., Silberstein C., Beaulieu V., et al. Postnatal expression of aquaporins in epithelial cells of the rat epididymis. Biol Reprod 74 (2006) 427-438
    • (2006) Biol Reprod , vol.74 , pp. 427-438
    • Da Silva, N.1    Silberstein, C.2    Beaulieu, V.3
  • 25
    • 33750382787 scopus 로고    scopus 로고
    • The Na,K-ATPase alpha4 isoform from humans has distinct enzymatic properties and is important for sperm motility
    • Sanchez G., Nguyen A.N., Timmerberg B., Tash J.S., and Blanco G. The Na,K-ATPase alpha4 isoform from humans has distinct enzymatic properties and is important for sperm motility. Mol Hum Reprod 12 (2006) 565-576
    • (2006) Mol Hum Reprod , vol.12 , pp. 565-576
    • Sanchez, G.1    Nguyen, A.N.2    Timmerberg, B.3    Tash, J.S.4    Blanco, G.5
  • 26
    • 33747587610 scopus 로고    scopus 로고
    • Na+/K+ATPase as a signaling molecule during bovine sperm capacitation
    • Thundathil J.C., Anzar M., and Buhr M.M. Na+/K+ATPase as a signaling molecule during bovine sperm capacitation. Biol Reprod 75 (2006) 308-317
    • (2006) Biol Reprod , vol.75 , pp. 308-317
    • Thundathil, J.C.1    Anzar, M.2    Buhr, M.M.3
  • 27
    • 33646191319 scopus 로고    scopus 로고
    • Odorant receptors and olfactory-like signaling mechanisms in mammalian sperm
    • Spehr M., Schwane K., Riffell J.A., Zimmer R.K., and Hatt H. Odorant receptors and olfactory-like signaling mechanisms in mammalian sperm. Mol Cell Endocrinol 250 (2006) 128-136
    • (2006) Mol Cell Endocrinol , vol.250 , pp. 128-136
    • Spehr, M.1    Schwane, K.2    Riffell, J.A.3    Zimmer, R.K.4    Hatt, H.5
  • 28
    • 33748662671 scopus 로고    scopus 로고
    • Proteins associated with soluble adenylyl cyclase in sea urchin sperm flagella
    • Nomura M., and Vacquier V.D. Proteins associated with soluble adenylyl cyclase in sea urchin sperm flagella. Cell Motil Cytoskeleton 63 (2006) 582-590
    • (2006) Cell Motil Cytoskeleton , vol.63 , pp. 582-590
    • Nomura, M.1    Vacquier, V.D.2
  • 29
    • 33646172012 scopus 로고    scopus 로고
    • Insights into sperm cell motility signaling through sNHE and the CatSpers
    • Quill T.A., Wang D., and Garbers D.L. Insights into sperm cell motility signaling through sNHE and the CatSpers. Mol Cell Endocrinol 250 (2006) 84-92
    • (2006) Mol Cell Endocrinol , vol.250 , pp. 84-92
    • Quill, T.A.1    Wang, D.2    Garbers, D.L.3
  • 30
    • 33749187944 scopus 로고    scopus 로고
    • A K+-selective cGMP-gated ion channel controls chemosensation of sperm
    • Strünker T., Weyand I., Bönigk W., et al. A K+-selective cGMP-gated ion channel controls chemosensation of sperm. Nat Cell Biol 8 (2006) 1149-1154
    • (2006) Nat Cell Biol , vol.8 , pp. 1149-1154
    • Strünker, T.1    Weyand, I.2    Bönigk, W.3
  • 31
  • 32
    • 38149095757 scopus 로고    scopus 로고
    • Sperm activation: role of reactive oxygen species and kinases
    • de Lamirande E., and O'Flaherty C. Sperm activation: role of reactive oxygen species and kinases. Biochim Biophys Acta 1784 (2008) 106-115
    • (2008) Biochim Biophys Acta , vol.1784 , pp. 106-115
    • de Lamirande, E.1    O'Flaherty, C.2
  • 33
    • 33746307519 scopus 로고    scopus 로고
    • Multiple glycolytic enzymes are tightly bound to the fibrous sheath of mouse spermatozoa
    • Krisfalusi M., Miki K., Magyar P.L., and O'Brien D.A. Multiple glycolytic enzymes are tightly bound to the fibrous sheath of mouse spermatozoa. Biol Reprod 75 (2006) 270-278
    • (2006) Biol Reprod , vol.75 , pp. 270-278
    • Krisfalusi, M.1    Miki, K.2    Magyar, P.L.3    O'Brien, D.A.4
  • 34
    • 9344243516 scopus 로고    scopus 로고
    • Glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme, is required for sperm motility and male fertility
    • Miki K., Qu W., Goulding E.H., et al. Glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme, is required for sperm motility and male fertility. Proc Natl Acad Sci USA 101 (2004) 16501-16506
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 16501-16506
    • Miki, K.1    Qu, W.2    Goulding, E.H.3
  • 35
    • 33751516087 scopus 로고    scopus 로고
    • Testosterone gel combined with depomedroxyprogesterone acetate is an effective male hormonal contraceptive regimen and is not enhanced by the addition of a GnRH antagonist
    • Page S.T., Amory J.K., Anawalt B.D., et al. Testosterone gel combined with depomedroxyprogesterone acetate is an effective male hormonal contraceptive regimen and is not enhanced by the addition of a GnRH antagonist. J Clin Endocrinol Metab 91 (2006) 4374-4380
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 4374-4380
    • Page, S.T.1    Amory, J.K.2    Anawalt, B.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.