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Volumn 147, Issue 6, 2008, Pages 990-995

Interactive effects of COMT Val108/158Met and MTHFR C677T on executive function in schizophrenia

Author keywords

COMT; Executive function; Methylation; MTHFR; Schizophrenia

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; ATYPICAL ANTIPSYCHOTIC AGENT; CATECHOL METHYLTRANSFERASE; DOPAMINE; METHIONINE; NEUROLEPTIC AGENT; VALINE;

EID: 51449089365     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.30684     Document Type: Article
Times cited : (53)

References (46)
  • 1
    • 2142814375 scopus 로고    scopus 로고
    • Methylomics in psychiatry: Modulation of gene-environment interactions may be through DNA methylation
    • Part B
    • Abdolmaleky HM, Smith CL, Faraone SV, Shafa R, Stone W, Glatt SJ, Tsuang MT. 2004. Methylomics in psychiatry: Modulation of gene-environment interactions may be through DNA methylation. Am J Med Genet Part B 127B(1):51-59.
    • (2004) Am J Med Genet , vol.127 B , Issue.1 , pp. 51-59
    • Abdolmaleky, H.M.1    Smith, C.L.2    Faraone, S.V.3    Shafa, R.4    Stone, W.5    Glatt, S.J.6    Tsuang, M.T.7
  • 3
    • 51449092305 scopus 로고    scopus 로고
    • Effects of the catechol-O-methyltransferase Val(158)Met polymorphism on executive function: A meta-analysis of the Wisconsin Card Sort Test in schizophrenia and healthy controls
    • Barnett JH, Jones PB, Robbins TW, Muller U. 2007. Effects of the catechol-O-methyltransferase Val(158)Met polymorphism on executive function: A meta-analysis of the Wisconsin Card Sort Test in schizophrenia and healthy controls. Biol Psychiatry 60(2):141-151.
    • (2007) Biol Psychiatry , vol.60 , Issue.2 , pp. 141-151
    • Barnett, J.H.1    Jones, P.B.2    Robbins, T.W.3    Muller, U.4
  • 7
    • 6344265879 scopus 로고    scopus 로고
    • Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): Effects on mRNA, protein, and enzyme activity in postmortem human brain
    • Chen J, Lipska BK, Halim N, Ma QD, Matsumoto M, Melhem S, Kolachana BS, Hyde TM, Herman MM, Apud J, et al. 2004. Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): Effects on mRNA, protein, and enzyme activity in postmortem human brain. Am J Hum Genet 75(5):807-821.
    • (2004) Am J Hum Genet , vol.75 , Issue.5 , pp. 807-821
    • Chen, J.1    Lipska, B.K.2    Halim, N.3    Ma, Q.D.4    Matsumoto, M.5    Melhem, S.6    Kolachana, B.S.7    Hyde, T.M.8    Herman, M.M.9    Apud, J.10
  • 9
    • 51449087270 scopus 로고    scopus 로고
    • Genetic Variation in Catechol-O-Methyltransferase: Effects on Working Memory in Schizophrenic Patients, Their Siblings, and Healthy Controls
    • in press
    • Diaz-Asper CM, Goldberg TE, Kolachana BS, Straub RE, Egan MF, Weinberger DR. 2007. Genetic Variation in Catechol-O-Methyltransferase: Effects on Working Memory in Schizophrenic Patients, Their Siblings, and Healthy Controls. Biol Psychiatry (in press).
    • (2007) Biol Psychiatry
    • Diaz-Asper, C.M.1    Goldberg, T.E.2    Kolachana, B.S.3    Straub, R.E.4    Egan, M.F.5    Weinberger, D.R.6
  • 11
    • 0018195837 scopus 로고
    • N5,10-methylenetetrahydrofolate reductase activity in autopsied brain parts of chronic schizophrenics and controls and in vitro tryptoline formation
    • Elliott GR, Sutherland K, Erdelyi E, Ciaranello RD, Barchas JD, Wyatt RJ. 1978. N5,10-methylenetetrahydrofolate reductase activity in autopsied brain parts of chronic schizophrenics and controls and in vitro tryptoline formation. Biol Psychiatry 13(6):695-708.
    • (1978) Biol Psychiatry , vol.13 , Issue.6 , pp. 695-708
    • Elliott, G.R.1    Sutherland, K.2    Erdelyi, E.3    Ciaranello, R.D.4    Barchas, J.D.5    Wyatt, R.J.6
  • 12
    • 12144252916 scopus 로고    scopus 로고
    • Catechol-O-methyltransferase gene Val/Met functional polymorphism and risk of schizophrenia: A large-scale association study plus meta-analysis
    • Fan JB, Zhang CS, Gu NF, Li XW, Sun WW, Wang HY, Feng GY, St Clair D, He L. 2005. Catechol-O-methyltransferase gene Val/Met functional polymorphism and risk of schizophrenia: A large-scale association study plus meta-analysis. Biol Psychiatry 57(2):139-144.
    • (2005) Biol Psychiatry , vol.57 , Issue.2 , pp. 139-144
    • Fan, J.B.1    Zhang, C.S.2    Gu, N.F.3    Li, X.W.4    Sun, W.W.5    Wang, H.Y.6    Feng, G.Y.7    St Clair, D.8    He, L.9
  • 13
    • 0016670730 scopus 로고
    • Folate-responsive homocystinuria and "schizophrenia". A defect in methylation due to deficient 5,10-methylenetetrahydrofolate reductase activity
    • Freeman JM, Finkelstein JD, Mudd SH. 1975. Folate-responsive homocystinuria and "schizophrenia". A defect in methylation due to deficient 5,10-methylenetetrahydrofolate reductase activity. N Engl J Med 292(10):491-496.
    • (1975) N Engl J Med , vol.292 , Issue.10 , pp. 491-496
    • Freeman, J.M.1    Finkelstein, J.D.2    Mudd, S.H.3
  • 16
    • 33845887461 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase (MTHFR) genetic polymorphisms and psychiatric disorders: A HuGE review
    • Gilbody S, Lewis S, Lightfoot T. 2007. Methylenetetrahydrofolate reductase (MTHFR) genetic polymorphisms and psychiatric disorders: A HuGE review. Am J Epidemiol 165(1):1-13.
    • (2007) Am J Epidemiol , vol.165 , Issue.1 , pp. 1-13
    • Gilbody, S.1    Lewis, S.2    Lightfoot, T.3
  • 17
    • 0028278952 scopus 로고
    • Relations between neuropsychological performance and brain morphological and physiological measures in monozygotic twins discordant for schizophrenia
    • Goldberg TE, Torrey EF, Berman KF, Weinberger DR. 1994. Relations between neuropsychological performance and brain morphological and physiological measures in monozygotic twins discordant for schizophrenia. Psychiatry Res 55(1):51-61.
    • (1994) Psychiatry Res , vol.55 , Issue.1 , pp. 51-61
    • Goldberg, T.E.1    Torrey, E.F.2    Berman, K.F.3    Weinberger, D.R.4
  • 18
    • 0030460739 scopus 로고    scopus 로고
    • Regional and cellular fractionation of working memory
    • Goldman-Rakic PS. 1996. Regional and cellular fractionation of working memory. Proc Natl Acad Sci USA 93(24):13473-13480.
    • (1996) Proc Natl Acad Sci USA , vol.93 , Issue.24 , pp. 13473-13480
    • Goldman-Rakic, P.S.1
  • 22
    • 15944428573 scopus 로고    scopus 로고
    • Ho BC, Wassink TH, O'Leary DS, Sheffield VC, Andreasen NC. 2005. Catechol-O-methyl transferase Val158Met gene polymorphism in schizophrenia: Working memory, frontal lobe MRI morphology and frontal cerebral blood flow. Mol Psychiatry 10229:287-298.
    • Ho BC, Wassink TH, O'Leary DS, Sheffield VC, Andreasen NC. 2005. Catechol-O-methyl transferase Val158Met gene polymorphism in schizophrenia: Working memory, frontal lobe MRI morphology and frontal cerebral blood flow. Mol Psychiatry 10229:287-298.
  • 23
    • 33846577275 scopus 로고    scopus 로고
    • Association of the methylenetetrahydrofolate reductase C677T polymorphism and fracture risk in Chinese postmenopausal women
    • Hong X, Hsu YH, Terwedow H, Tang G, Liu X, Jiang S, Xu X, Xu X. 2007. Association of the methylenetetrahydrofolate reductase C677T polymorphism and fracture risk in Chinese postmenopausal women. Bone 40(3):737-742.
    • (2007) Bone , vol.40 , Issue.3 , pp. 737-742
    • Hong, X.1    Hsu, Y.H.2    Terwedow, H.3    Tang, G.4    Liu, X.5    Jiang, S.6    Xu, X.7    Xu, X.8
  • 24
    • 0035983302 scopus 로고    scopus 로고
    • Catechol-O-methyltransferase Val-108/158-Met gene variants associated with performance on the Wisconsin Card Sorting Test
    • Joober R, Gauthier J, Lal S, Bloom D, Lalonde P, Rouleau G, Benkelfat C, Labelle A. 2002. Catechol-O-methyltransferase Val-108/158-Met gene variants associated with performance on the Wisconsin Card Sorting Test. Arch Gen Psychiatry 59(7):662-663.
    • (2002) Arch Gen Psychiatry , vol.59 , Issue.7 , pp. 662-663
    • Joober, R.1    Gauthier, J.2    Lal, S.3    Bloom, D.4    Lalonde, P.5    Rouleau, G.6    Benkelfat, C.7    Labelle, A.8
  • 25
    • 0023606101 scopus 로고
    • The positive and negative syndrome scale (PANSS) for schizophrenia
    • Kay SR, Fiszbein A, Opler LA. 1987. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull 13(2):261-276.
    • (1987) Schizophr Bull , vol.13 , Issue.2 , pp. 261-276
    • Kay, S.R.1    Fiszbein, A.2    Opler, L.A.3
  • 26
    • 78651003954 scopus 로고
    • Psychiatric observations on induced vitamin B complex deficiency in psychotic patients
    • Kreisler O, Liebert E, Horwitt MK. 1948. Psychiatric observations on induced vitamin B complex deficiency in psychotic patients. Am J Psychiatry 105:102-106.
    • (1948) Am J Psychiatry , vol.105 , pp. 102-106
    • Kreisler, O.1    Liebert, E.2    Horwitt, M.K.3
  • 28
    • 0032800665 scopus 로고    scopus 로고
    • Wisconsin Card Sorting Test performance following head injury: Dorsolateral fronto-striatal circuit activity predicts perseveration
    • Lombardi WJ, Andreason PJ, Sirocco KY, Rio DE, Gross RE, Umhau JC, Hommer DW. 1999. Wisconsin Card Sorting Test performance following head injury: Dorsolateral fronto-striatal circuit activity predicts perseveration. J Clin Exp Neuropsychol 21(1):2-16.
    • (1999) J Clin Exp Neuropsychol , vol.21 , Issue.1 , pp. 2-16
    • Lombardi, W.J.1    Andreason, P.J.2    Sirocco, K.Y.3    Rio, D.E.4    Gross, R.E.5    Umhau, J.C.6    Hommer, D.W.7
  • 29
    • 0015318864 scopus 로고
    • S-adenosylmethionine and catechol-O-methyl-transferase in schizophrenia
    • Matthysse S, Baldessarini RJ. 1972. S-adenosylmethionine and catechol-O-methyl-transferase in schizophrenia. Am J Psychiatry 128(10):1310-1312.
    • (1972) Am J Psychiatry , vol.128 , Issue.10 , pp. 1310-1312
    • Matthysse, S.1    Baldessarini, R.J.2
  • 30
    • 33745039815 scopus 로고    scopus 로고
    • Evidence for monozygotic twin (MZ) discordance in methylation level at two CpG sites in the promoter region of the catechol-O-methyltransferase (COMT) gene
    • Part B
    • Mill J, Dempster E, Caspi A, Williams B, Moffitt T, Craig I. 2006. Evidence for monozygotic twin (MZ) discordance in methylation level at two CpG sites in the promoter region of the catechol-O-methyltransferase (COMT) gene. Am J Med Genet Part B 141B(4):421-425.
    • (2006) Am J Med Genet , vol.141 B , Issue.4 , pp. 421-425
    • Mill, J.1    Dempster, E.2    Caspi, A.3    Williams, B.4    Moffitt, T.5    Craig, I.6
  • 31
    • 23744517092 scopus 로고    scopus 로고
    • Lack of association of the COMT (Val158/108 Met) gene and schizophrenia: A meta-analysis of case-control studies
    • Munafo MR, Bowes L, Clark TG, Flint J. 2005. Lack of association of the COMT (Val158/108 Met) gene and schizophrenia: A meta-analysis of case-control studies. Mol Psychiatry 10(8):765-770.
    • (2005) Mol Psychiatry , vol.10 , Issue.8 , pp. 765-770
    • Munafo, M.R.1    Bowes, L.2    Clark, T.G.3    Flint, J.4
  • 32
    • 33846363929 scopus 로고    scopus 로고
    • Evidence for statistical epistasis between catechol-O-methyltransferase (COMT) and polymorphisms in RGS4, G72 (DAOA), GRM3, and DISC1: Influence on risk of schizophrenia
    • Nicodemus KK, Kolachana BS, Vakkalanka R, Straub RE, Giegling I, Egan MF, Rujescu D, Weinberger DR. 2007. Evidence for statistical epistasis between catechol-O-methyltransferase (COMT) and polymorphisms in RGS4, G72 (DAOA), GRM3, and DISC1: Influence on risk of schizophrenia. Hum Genet 120(6): 889-906.
    • (2007) Hum Genet , vol.120 , Issue.6 , pp. 889-906
    • Nicodemus, K.K.1    Kolachana, B.S.2    Vakkalanka, R.3    Straub, R.E.4    Giegling, I.5    Egan, M.F.6    Rujescu, D.7    Weinberger, D.R.8
  • 35
    • 2942567866 scopus 로고    scopus 로고
    • New evidence of association between COMT gene and prefrontal neurocognitive function in healthy individuals from sibling pairs discordant for psychosis
    • Rosa A, Peralta V, Cuesta MJ, Zarzuela A, Serrano F, Martinez-Larrea A, Fananas L. 2004. New evidence of association between COMT gene and prefrontal neurocognitive function in healthy individuals from sibling pairs discordant for psychosis. Am J Psychiatry 161(6):1110-1112.
    • (2004) Am J Psychiatry , vol.161 , Issue.6 , pp. 1110-1112
    • Rosa, A.1    Peralta, V.2    Cuesta, M.J.3    Zarzuela, A.4    Serrano, F.5    Martinez-Larrea, A.6    Fananas, L.7
  • 37
    • 0038069365 scopus 로고    scopus 로고
    • Multiple promoters of catechol-O-methyltransferase gene are selectively inactivated by CpG hypermethylation in endometrial cancer
    • Sasaki M, Kaneuchi M, Sakuragi N, Dahiya R. 2003. Multiple promoters of catechol-O-methyltransferase gene are selectively inactivated by CpG hypermethylation in endometrial cancer. Cancer Res 63(12):3101-3106.
    • (2003) Cancer Res , vol.63 , Issue.12 , pp. 3101-3106
    • Sasaki, M.1    Kaneuchi, M.2    Sakuragi, N.3    Dahiya, R.4
  • 38
    • 0014723449 scopus 로고
    • A rating scale for extrapyramidal side effects
    • Simpson GM, Angus JW. 1970. A rating scale for extrapyramidal side effects. Acta Psychiatr Scand Suppl 212:11-19.
    • (1970) Acta Psychiatr Scand , Issue.SUPPL. 212 , pp. 11-19
    • Simpson, G.M.1    Angus, J.W.2
  • 39
    • 30344481921 scopus 로고    scopus 로고
    • Cognitive deficits in unaffected first-degree relatives of schizophrenia patients: A meta-analytic review of putative endophenotypes
    • Snitz BE, Macdonald AW III, Carter CS. 2006. Cognitive deficits in unaffected first-degree relatives of schizophrenia patients: A meta-analytic review of putative endophenotypes. Schizophr Bull 32(1):179-194.
    • (2006) Schizophr Bull , vol.32 , Issue.1 , pp. 179-194
    • Snitz, B.E.1    Macdonald III, A.W.2    Carter, C.S.3
  • 40
    • 0027447494 scopus 로고
    • Factors of the Wisconsin Card Sorting Test as measures of frontal-lobe function in schizophrenia and in chronic alcoholism
    • Sullivan EV, Mathalon DH, Zipursky RB, Kersteen-Tucker Z, Knight RT, Pfefferbaum A. 1993. Factors of the Wisconsin Card Sorting Test as measures of frontal-lobe function in schizophrenia and in chronic alcoholism. Psychiatry Res 46(2):175-199.
    • (1993) Psychiatry Res , vol.46 , Issue.2 , pp. 175-199
    • Sullivan, E.V.1    Mathalon, D.H.2    Zipursky, R.B.3    Kersteen-Tucker, Z.4    Knight, R.T.5    Pfefferbaum, A.6
  • 42
    • 30844447432 scopus 로고    scopus 로고
    • Memory tests in first-degree adult relatives of schizophrenic patients: A meta-analysis
    • Trandafir A, Meary A, Schurhoff F, Leboyer M, Szoke A. 2006. Memory tests in first-degree adult relatives of schizophrenic patients: A meta-analysis. Schizophr Res 81(2-3):217-226.
    • (2006) Schizophr Res , vol.81 , Issue.2-3 , pp. 217-226
    • Trandafir, A.1    Meary, A.2    Schurhoff, F.3    Leboyer, M.4    Szoke, A.5
  • 43
    • 33745703902 scopus 로고    scopus 로고
    • Catechol -O-methyltransferase, cognition, and psychosis: Val158Met and beyond
    • Tunbridge EM, Harrison PJ, Weinberger DR. 2006. Catechol -O-methyltransferase, cognition, and psychosis: Val158Met and beyond. Biol Psychiatry 60(2):141-151.
    • (2006) Biol Psychiatry , vol.60 , Issue.2 , pp. 141-151
    • Tunbridge, E.M.1    Harrison, P.J.2    Weinberger, D.R.3
  • 46
    • 33645873908 scopus 로고    scopus 로고
    • Under the curve: Critical issues for elucidating D1 receptor function in working memory
    • Williams GV, Castner SA. 2006. Under the curve: Critical issues for elucidating D1 receptor function in working memory. Neuroscience 139(1):263-276.
    • (2006) Neuroscience , vol.139 , Issue.1 , pp. 263-276
    • Williams, G.V.1    Castner, S.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.