A search within the IL-1 type I receptor reveals a peptide with hydropathic complementarity to the IL-1β trigger loop which binds to IL-1 and inhibits in vitro responses

Molecular Immunology

Volumn 36, Issue 17, 1999, Pages 1141-1148

  Heal, Jon R ^a   Bino, Silvia ^b   Ray, Keith P ^c   Christie, Gary ^c   Miller, Andrew D ^a   Raynes, John G ^b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b Molecular Immunology Unit   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Antisense peptide; Cytokine inhibitor; Hydrophobic complementarity; Interleukin 1

Indexed keywords

AMINO ACID; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1BETA;

AMINO ACID SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; IMMUNE RESPONSE; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; RECEPTOR BINDING; SEQUENCE HOMOLOGY;

ALKALINE PHOSPHATASE; AMINO ACID SEQUENCE; APOLIPOPROTEINS; BINDING SITES; BIOSENSING TECHNIQUES; CELL LINE; HUMANS; INTERLEUKIN-1; PEPTIDE FRAGMENTS; RECEPTORS, INTERLEUKIN-1; RECEPTORS, INTERLEUKIN-1 TYPE I; SERUM AMYLOID A PROTEIN;

EID: 0033376488     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-5890(99)00129-7     Document Type: Article

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