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Volumn 27, Issue 17, 2004, Pages 2743-2758

Determination of gefitinib in plasma by liquid chromatography with a C 12 column and electrospray tandem mass spectrometry detection

Author keywords

Electrospray tandem mass spectrometry; Gefitinib; Liquid chromatography; Plasma

Indexed keywords

ACETONITRILE; COLUMN CHROMATOGRAPHY; EXTRACTION; MASS SPECTROMETERS; MASS SPECTROMETRY; SEPARATION;

EID: 5144224887     PISSN: 10826076     EISSN: None     Source Type: Journal    
DOI: 10.1081/JLC-200029312     Document Type: Article
Times cited : (17)

References (18)
  • 1
    • 0034068319 scopus 로고    scopus 로고
    • Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor
    • Ciardiello, F.; Caputo, R.; Bianco, R.; Damiano, V.; Pomatico, G.; De Placido, S. Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor. Clin. Cancer Res. 2000, 6, 2053-2063.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 2053-2063
    • Ciardiello, F.1    Caputo, R.2    Bianco, R.3    Damiano, V.4    Pomatico, G.5    De Placido, S.6
  • 2
    • 0034489914 scopus 로고    scopus 로고
    • Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase
    • Sirotnak, F.M.; Zakowski, M.F.; Miller, V.A.; Scher, H.I.; Kris, M.G. Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase. Clin. Cancer Res. 2000, 6, 4885-4892.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 4885-4892
    • Sirotnak, F.M.1    Zakowski, M.F.2    Miller, V.A.3    Scher, H.I.4    Kris, M.G.5
  • 3
    • 0003200669 scopus 로고    scopus 로고
    • Evaluation of ZD1839 (Iressa) alone and in combination with irinotecan (CPT-11) against pediatric solid tumor xenografts
    • Houghton, P.J.; Cheshire, P.J.; Harwood, F.G. Evaluation of ZD1839 (Iressa) alone and in combination with irinotecan (CPT-11) against pediatric solid tumor xenografts. Proc 11th NCI-EORTC-AACR Symposium 6, 2000; 379.
    • (2000) Proc. 11th NCI-EORTC-AACR Symposium 6 , pp. 379
    • Houghton, P.J.1    Cheshire, P.J.2    Harwood, F.G.3
  • 4
    • 0036569870 scopus 로고    scopus 로고
    • ZD1839, a selective oral epidermal growth factor receptor-tyrosine kinase inhibitor, is well tolerated and active in patients with solid, malignant tumors: Results of a phase I trial
    • Ranson, M.; Hammond, L.A.; Ferry, D.; Kris, M.; Tullo, A.; Murray, P.I. ZD1839, a selective oral epidermal growth factor receptor-tyrosine kinase inhibitor, is well tolerated and active in patients with solid, malignant tumors: results of a phase I trial. J. Clin. Oncol. 2002, 20, 2240-2250.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 2240-2250
    • Ranson, M.1    Hammond, L.A.2    Ferry, D.3    Kris, M.4    Tullo, A.5    Murray, P.I.6
  • 5
    • 0035023187 scopus 로고    scopus 로고
    • Pharmacokinetics and tolerability of the orally active selective epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in healthy volunteers
    • Swaisland, H.; Laight, A.; Stafford, L.; Jones, H.; Morris, C.; Dane, A.; Yates, R. Pharmacokinetics and tolerability of the orally active selective epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in healthy volunteers. Clin. Pharmacokinet. 2001, 40, 297-306.
    • (2001) Clin. Pharmacokinet. , vol.40 , pp. 297-306
    • Swaisland, H.1    Laight, A.2    Stafford, L.3    Jones, H.4    Morris, C.5    Dane, A.6    Yates, R.7
  • 6
    • 0037106377 scopus 로고    scopus 로고
    • Selective oral epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 is generally well-tolerated and has activity in non-small-cell lung cancer and other solid tumors: Results of a phase I trial
    • Herbst, R.S.; Maddox, A.M.; Rothenberg, M.L.; Small, E.J.; Rubin, E.H.; Baselga, J. Selective oral epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 is generally well-tolerated and has activity in non-small-cell lung cancer and other solid tumors: results of a phase I trial. J. Clin. Oncol. 2002, 20, 3815-3825.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 3815-3825
    • Herbst, R.S.1    Maddox, A.M.2    Rothenberg, M.L.3    Small, E.J.4    Rubin, E.H.5    Baselga, J.6
  • 7
    • 0037142314 scopus 로고    scopus 로고
    • A sensitive assay for ZD1839 (Iressa) in human plasma by liquid-liquid extraction and high performance liquid chromatography with mass spectrometric detection: Validation and use in Phase I clinical trials
    • Jones, H.K.; Stafford, L.E.; Swaisland, H.C.; Payne, R. A sensitive assay for ZD1839 (Iressa) in human plasma by liquid-liquid extraction and high performance liquid chromatography with mass spectrometric detection: validation and use in Phase I clinical trials. J. Pharm. Biomed. Anal. 2002, 29, 221-228.
    • (2002) J. Pharm. Biomed. Anal. , vol.29 , pp. 221-228
    • Jones, H.K.1    Stafford, L.E.2    Swaisland, H.C.3    Payne, R.4
  • 8
    • 0033832634 scopus 로고    scopus 로고
    • Applications of hyphenated LC-MS techniques in pharmaceutical analysis
    • Ermer, J.; Vogel, M. Applications of hyphenated LC-MS techniques in pharmaceutical analysis. Biomed. Chromatogr. 2000, 14, 373-383.
    • (2000) Biomed. Chromatogr. , vol.14 , pp. 373-383
    • Ermer, J.1    Vogel, M.2
  • 9
    • 0033953172 scopus 로고    scopus 로고
    • Mass spectrometric study of randomly methylated beta-cyclodextrins using ionspray, atmospheric pressure chemical ionization and matrix-assisted laser desorption/ionization
    • Mercier, J.P.; Debrun, J.L.; Dreux, M.; Elfakir, C.; Hakim, B. Mass spectrometric study of randomly methylated beta-cyclodextrins using ionspray, atmospheric pressure chemical ionization and matrix-assisted laser desorption/ionization. Rapid Commun. Mass Spectrom. 2000, 14, 68-70.
    • (2000) Rapid Commun. Mass Spectrom. , vol.14 , pp. 68-70
    • Mercier, J.P.1    Debrun, J.L.2    Dreux, M.3    Elfakir, C.4    Hakim, B.5
  • 10
    • 0029014207 scopus 로고
    • Liquid-chromatography mass-spectrometry - General-principles and instrumentation
    • Niessen, W.M.A.; Tinke, A.P. Liquid-chromatography mass-spectrometry - general-principles and instrumentation. J. Chromatogr. A 1995, 703, 37-57.
    • (1995) J. Chromatogr. A , vol.703 , pp. 37-57
    • Niessen, W.M.A.1    Tinke, A.P.2
  • 11
    • 0034893475 scopus 로고    scopus 로고
    • Method for the quantitative analysis of cilostazol and its metabolites in human plasma using LC/MS/MS
    • Bramer, S.L.; Tata, P.N.; Vengurlekar, S.S.; Brisson, J.H. Method for the quantitative analysis of cilostazol and its metabolites in human plasma using LC/MS/MS. J. Pharm. Biomed. Anal. 2001, 26, 637-650.
    • (2001) J. Pharm. Biomed. Anal. , vol.26 , pp. 637-650
    • Bramer, S.L.1    Tata, P.N.2    Vengurlekar, S.S.3    Brisson, J.H.4
  • 12
    • 0032737143 scopus 로고    scopus 로고
    • Validation of a liquid chromatography ionspray mass spectrometry method for the analysis of flavanones, flavones and flavonols
    • Careri, M.; Elviri, L.; Mangia, A. Validation of a liquid chromatography ionspray mass spectrometry method for the analysis of flavanones, flavones and flavonols. Rapid Commun. Mass Spectrom. 1999, 13, 2399-2405.
    • (1999) Rapid Commun. Mass Spectrom. , vol.13 , pp. 2399-2405
    • Careri, M.1    Elviri, L.2    Mangia, A.3
  • 13
    • 0035340925 scopus 로고    scopus 로고
    • Electrospray and tandem mass spectrometry in biochemistry
    • Griffiths, W.J.; Jonsson, A.P.; Liu, S.; Rai, D.K.; Wang, Y. Electrospray and tandem mass spectrometry in biochemistry. Biochem. J. 2001, 355, 545-561.
    • (2001) Biochem. J. , vol.355 , pp. 545-561
    • Griffiths, W.J.1    Jonsson, A.P.2    Liu, S.3    Rai, D.K.4    Wang, Y.5
  • 14
    • 0030621966 scopus 로고    scopus 로고
    • Studying noncovalent protein complexes by electrospray ionization mass spectrometry
    • Loo, J.A. Studying noncovalent protein complexes by electrospray ionization mass spectrometry. Mass Spectrom. Rev. 1997, 16, 1-23.
    • (1997) Mass Spectrom. Rev. , vol.16 , pp. 1-23
    • Loo, J.A.1
  • 15
    • 0033834358 scopus 로고    scopus 로고
    • Quantitative determination of pravastatin and its biotransformation products in human serum by turbo ion spray LC/MS/MS
    • Mulvana, D.; Jemal, M.; Pulver, S.C. Quantitative determination of pravastatin and its biotransformation products in human serum by turbo ion spray LC/MS/MS. J. Pharm. Biomed. Anal. 2000, 23, 851-866.
    • (2000) J. Pharm. Biomed. Anal. , vol.23 , pp. 851-866
    • Mulvana, D.1    Jemal, M.2    Pulver, S.C.3
  • 16
    • 0034540560 scopus 로고    scopus 로고
    • Automated in-tube solid phase micro-extraction coupled with HPLC-ES-MS for the determination of catechins and caffeine in tea
    • Wu, J.; Xie, W.; Pawliszyn, J. Automated in-tube solid phase micro-extraction coupled with HPLC-ES-MS for the determination of catechins and caffeine in tea. Analyst 2000, 125, 2216-2222.
    • (2000) Analyst , vol.125 , pp. 2216-2222
    • Wu, J.1    Xie, W.2    Pawliszyn, J.3
  • 17
    • 0032875515 scopus 로고    scopus 로고
    • Determination of L-753,037 in human plasma by liquid chromatography/turbo ionspray tandem mass spectrometry
    • Zhao, J.J.; Xie, I.; Rogers, J.D. Determination of L-753,037 in human plasma by liquid chromatography/turbo ionspray tandem mass spectrometry. J. Mass Spectrom. 1999, 34, 1018-1027.
    • (1999) J. Mass Spectrom. , vol.34 , pp. 1018-1027
    • Zhao, J.J.1    Xie, I.2    Rogers, J.D.3
  • 18
    • 0032996183 scopus 로고    scopus 로고
    • Quantitation of the acid and lactone forms of atorvastatin and its biotransformation products in human serum by high-performance liquid chromatography with electrospray tandem mass spectrometry
    • Jemal, M.; Ouyang, Z.; Chen, B.C.; Teitz, D. Quantitation of the acid and lactone forms of atorvastatin and its biotransformation products in human serum by high-performance liquid chromatography with electrospray tandem mass spectrometry. Rapid Commun. Mass Spectrom. 1999, 13, 1003-1015.
    • (1999) Rapid Commun. Mass Spectrom. , vol.13 , pp. 1003-1015
    • Jemal, M.1    Ouyang, Z.2    Chen, B.C.3    Teitz, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.