Clinically important factors influencing the diagnostic measurement of pleural fluid pH and glucose

American Journal of Respiratory and Critical Care Medicine

Volumn 178, Issue 5, 2008, Pages 483-490

  Rahman, Najib M ^a   Mishra, Eleanor K ^b   Davies, Helen E ^a   Davies, Robert J O ^a   Lee, Y C Gary ^a,c,d  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b NORFOLK AND NORWICH UNIVERSITY HOSPITAL   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d CHURCHILL HOSPITAL   (United Kingdom)

Author keywords

Glucose; Measurement; Ph; Pleural fluid

Indexed keywords

GLUCOSE; HEPARIN; LIDOCAINE;

AGED; ARTICLE; ASPIRATION; BLOOD GAS ANALYSIS; CLINICAL PROTOCOL; CONFIDENCE INTERVAL; DIAGNOSTIC ACCURACY; DIAGNOSTIC APPROACH ROUTE; EXUDATIVE PLEURISY; FEMALE; GLUCOSE ASSAY; GLUCOSE BLOOD LEVEL; HUMAN; MAJOR CLINICAL STUDY; MALE; PH; PH MEASUREMENT; PLEURA EFFUSION; PLEURA FLUID PH; PRIORITY JOURNAL; ROOM TEMPERATURE;

AGED; AIR; ANESTHETICS, LOCAL; ANTICOAGULANTS; BLOOD GAS ANALYSIS; FEMALE; GLUCOSE; HEPARIN; HUMANS; HYDROGEN-ION CONCENTRATION; LIDOCAINE; MALE; PLEURAL EFFUSION; REPRODUCIBILITY OF RESULTS; SPECIMEN HANDLING; TIME FACTORS;

EID: 51349162263     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200801-062OC     Document Type: Article

References (26)

1. Light RW, Lee YC. Textbook of pleural diseases, 2nd ed. London: Arnold Press; 2008.
2. Light RW. Pleural diseases, 5th ed. Philadelphia: Lippincott, Williams & Wilkins; 2007.
3. Maskell NA, Butland RJ. BTS guidelines for the investigation of a unilateral pleural effusion in adults. Thorax 2003;58:ii8-ii17.
4. Heffner JE, Nietert PJ, Barbieri C. Pleural fluid pH as a predictor of survival for patients with malignant pleural effusions. Chest 2000;117:79-86.
5. Heffner JE, Heffner JN, Brown LK. Multilevel and continuous pleural fluid pH likelihood ratios for evaluating malignant pleural effusions. Chest 2003;123:1887-1894.
6. Rodriguez-Panadero F, Lopez MJ. Low glucose and pH levels in malignant pleural effusions: diagnostic significance and prognostic value in respect to pleurodesis. Am Rev Respir Dis 1989;139:663-667.
7. Sahn SA, Good JT Jr. Pleural fluid pH in malignant effusions: diagnostic, prognostic, and therapeutic implications. Ann Intern Med 1988;108:345-349.
8. Antony VB, Loddenkemper R, Astoul P, Boutin C, Goldstraw P, Hott J, Rodriguez PF, Sahn SA. Management of malignant pleural effusions. Am J Respir Crit Care Med 2000;162:1987-2001.
9. Antony VB, Loddenkemper R, Astoul P, Boutin C, Goldstraw P, Hott J, Rodriguez PF, Sahn SA. Management of malignant pleural effusions. Eur Respir J 2001;18:402-419.
10. Antunes G, Neville E, Duffy J, Ali N. BTS guidelines for the management of malignant pleural effusions. Thorax 2003;58:ii29-ii38.
11. Davies CW, Gleeson FV, Davies RJ. BTS guidelines for the management of pleural infection. Thorax 2003;58:ii18-ii28.
12. Heffner JE, Brown LK, Barbieri C, DeLeo JM. Pleural fluid chemical analysis in parapneumonic effusions: a meta-analysis. Am J Respir Crit Care Med 1995;151:1700-1708.
13. Light RW, MacGregor MI, Ball WC Jr, Luchsinger PC. Diagnostic significance of pleural fluid pH and PCO2. Chest 1973;64:591-596.
14. Light RW, Girard WM, Jenkinson SG, George RB. Parapneumonic effusions. Am J Med 1980;69:507-512.
15. Maskell NA, Batt S, Hedley EL, Davies CW, Gillespie SH, Davies RJ. The bacteriology of pleural infection by genetic and standard methods and its mortality significance. Am J Respir Crit Care Med 2006;174:817-823.
16. Maskell NA, Davies CW, Nunn AJ, Hedley EL, Gleeson FV, Miller R, Gabe R, Rees GL, Peto TE, Woodhead MA, et al. UK controlled trial of intrapleural streptokinase for pleural infection. N Engl J Med 2005;352:865-874.
17. Cheng DS, Rodriguez RM, Rogers J, Wagster M, Starnes DL, Light RW. Comparison of pleural fluid pH values obtained using blood gas machine, pH meter, and pH indicator strip. Chest 1998;114:1368-1372.
18. Sarodia BD, Goldstein LS, Laskowski DM, Mehta AC, Arroliga AC. Does pleural fluid pH change significantly at room temperature during the first hour following thoracentesis? Chest 2000;117:1043-1048.
19. Haro-Estarriol M, Baldo-Padro X, Lora-Diez M, Rubio-Garay M, Rubio-Goday M, Sebastian-Quetglas F. Changes in the acid-base equilibrium of pleural fluid during the first 2 hours after thoracentesis [in Spanish]. Arch Bronconeumol 2005;41:612-617.
20. Ross Hill A. Avoiding air in pleural fluid pH. Chest 1998;113:1729.
21. Potts DE, Taryle DA, Sahn SA. The glucose-pH relationship in parapneumonic effusions. Arch Intern Med 1978;138:1378-1380.
22. Tietz NW. Clinical guide to laboratory tests, 3rd ed. Philadelphia: W.B. Saunders; 1995. pp. 268-269.
23. Tietz NW. Textbook of clinical chemistry, 3rd ed. Philadelphia: W.B. Saunders; 1999. pp. 777-778.
24. Jimenez CD, Diaz G, Perez-Rodriguez E, Prieto E, Yusen RD. Modification of pleural fluid pH by local anesthesia. Chest 1999;116:399-402.
25. Goldstein LS, McCarthy K, Mehta AC, Arroliga AC. Is direct collection of pleural fluid into a heparinized syringe important for determination of pleural pH? A brief report. Chest 1997;112:707-708.
26. Maskell NA, Gleeson FV, Darby M, Davies RJ. Diagnostically significant variations in pleural fluid pH in loculated parapneumonic effusions. Chest 2004;126:2022-2024.