Synthesis of [14C] - and [13C6]-labeled tipranavir and its potential hydroxyl metabolite and the glucuronide conjugate

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 51, Issue 8, 2008, Pages 314-320

  Latli, Bachir ^a   Hrapchak, Matt ^a   Easter, John A ^b   Stolle, Wayne T ^c   Grozinger, Karl ^a   Krishnamurthy, Dhileepkumar ^a   Senanayake, Chris H ^a  

^a BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

^b BRISTOL MYERS SQUIBB   (United States)

^c PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Carbon13; Carbon14; HIV AIDS; Radiosynthesis; Tipranavir

Indexed keywords

BENZOIC ACID; BIOMOLECULES; DISEASES;

CARBON 14; CARBON-13; COMBINATION TREATMENTS; GLUCURONIDE CONJUGATES; HIV INFECTION; HIV/AIDS; PROTEASE INHIBITOR; RADIOSYNTHESIS; SPECIFIC ACTIVITY; TIPRANAVIR;

METABOLITES;

BENZOIC ACID; CARBON 13; CARBON 14; GLUCURONIDE; HYDROXYL GROUP; NEVIRAPINE; RITONAVIR; STABLE ISOTOPE; TIPRANAVIR; TIPRANAVIR C 13; TIPRANAVIR C 14; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; CONJUGATION; GLUCURONIDATION; ISOTOPE LABELING; METABOLITE; SYNTHESIS;

EID: 51349160619     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1528     Document Type: Article

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