메뉴 건너뛰기




Volumn 81, Issue 969, 2008, Pages 685-692

The role of clinical imaging in oncological drug development

Author keywords

[No Author keywords available]

Indexed keywords

3' DEOXY 3' FLUOROTHYMIDINE F 18; ANTINEOPLASTIC AGENT; AXITINIB; BEVACIZUMAB; BIOLOGICAL MARKER; CONTRAST MEDIUM; FLUORODEOXYGLUCOSE F 18; IMATINIB; TRACER; UNCLASSIFIED DRUG;

EID: 51349157100     PISSN: 00071285     EISSN: None     Source Type: Journal    
DOI: 10.1259/bjr/16768437     Document Type: Review
Times cited : (19)

References (68)
  • 1
    • 4344645978 scopus 로고    scopus 로고
    • Can the pharmaceutical industry reduce attrition rates?
    • Kola I, Landis J. Can the pharmaceutical industry reduce attrition rates? Nat Rev Drug Discov 2004;3:711-5.
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 711-715
    • Kola, I.1    Landis, J.2
  • 3
    • 0037313516 scopus 로고    scopus 로고
    • Molecular imaging in drug discovery and development
    • Rudin M, Weissleder R. Molecular imaging in drug discovery and development. Nat Rev Drug Discov 2003;2:123-31.
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 123-131
    • Rudin, M.1    Weissleder, R.2
  • 5
    • 21544448884 scopus 로고    scopus 로고
    • Improved early clinical development through human microdosing studies
    • Wilding IR, Bell JA. Improved early clinical development through human microdosing studies. Drug Discov Today 2005;10:890-4.
    • (2005) Drug Discov Today , vol.10 , pp. 890-894
    • Wilding, I.R.1    Bell, J.A.2
  • 7
    • 33645036518 scopus 로고    scopus 로고
    • Commentary: The phase 0 microdosing concept
    • Garner RC, Lappin G. Commentary: the phase 0 microdosing concept. Br J Clin Pharmacol 2006;61:367-70.
    • (2006) Br J Clin Pharmacol , vol.61 , pp. 367-370
    • Garner, R.C.1    Lappin, G.2
  • 8
    • 0141706482 scopus 로고    scopus 로고
    • Positron emission tomography microdosing: A new concept with application in tracer and early clinical drug development
    • Bergstrom M, Grahnen A, Langstrom B. Positron emission tomography microdosing: a new concept with application in tracer and early clinical drug development. Eur J Clin Pharmacol 2003;59:357-66.
    • (2003) Eur J Clin Pharmacol , vol.59 , pp. 357-366
    • Bergstrom, M.1    Grahnen, A.2    Langstrom, B.3
  • 9
    • 85047695615 scopus 로고    scopus 로고
    • Cancer Research UK procedures in manufacture and toxicology of radiotracers intended for pre-phase I positron emission tomography studies in cancer patients
    • Aboagye EO, Luthra SK, Brady F, Poole K, Anderson H, Jones T, et al. Cancer Research UK procedures in manufacture and toxicology of radiotracers intended for pre-phase I positron emission tomography studies in cancer patients. Br J Cancer 2002;86:1052-6.
    • (2002) Br J Cancer , vol.86 , pp. 1052-1056
    • Aboagye, E.O.1    Luthra, S.K.2    Brady, F.3    Poole, K.4    Anderson, H.5    Jones, T.6
  • 10
    • 4544230516 scopus 로고    scopus 로고
    • Radiolabeled compounds in the development of cytotoxic agents
    • Kairemo KJ, Tähtinen M. Radiolabeled compounds in the development of cytotoxic agents. Curr Pharm Des 2004;10:2923-34.
    • (2004) Curr Pharm Des , vol.10 , pp. 2923-2934
    • Kairemo, K.J.1    Tähtinen, M.2
  • 12
    • 7244243743 scopus 로고    scopus 로고
    • Trends in the risks and benefits to patients with cancer participating in phase 1 clinical trials
    • Roberts TG Jr, Goulart BH, Squitieri L, Stallings SC, Halpern EF, Chabner BA, et al. Trends in the risks and benefits to patients with cancer participating in phase 1 clinical trials. JAMA 2004;292:2130-40.
    • (2004) JAMA , vol.292 , pp. 2130-2140
    • Roberts Jr, T.G.1    Goulart, B.H.2    Squitieri, L.3    Stallings, S.C.4    Halpern, E.F.5    Chabner, B.A.6
  • 13
    • 24944515034 scopus 로고    scopus 로고
    • Dynamic contrast-enhanced magnetic resonance imaging as a pharmacodynamic measure of response after acute dosing of AG-013736, an oral angiogenesis inhibitor, in patients with advanced solid tumors: Results from a phase I study
    • Liu G, Rugo HS, Wilding G, McShane TM, Evelhoch JL, Ng C, et al. Dynamic contrast-enhanced magnetic resonance imaging as a pharmacodynamic measure of response after acute dosing of AG-013736, an oral angiogenesis inhibitor, in patients with advanced solid tumors: results from a phase I study. J Clin Oncol 2005;23:5464-73.
    • (2005) J Clin Oncol , vol.23 , pp. 5464-5473
    • Liu, G.1    Rugo, H.S.2    Wilding, G.3    McShane, T.M.4    Evelhoch, J.L.5    Ng, C.6
  • 14
    • 0347615101 scopus 로고    scopus 로고
    • Dynamic contrast-enhanced magnetic resonance imaging as a biomarker for the pharmacological response of PTK787/ZK 222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases, in patients with advanced colorectal cancer and liver metastases: Results from two phase I studies
    • Morgan B, Thomas AL, Drevs J, Hennig J, Buchert M, Jivan A, et al. Dynamic contrast-enhanced magnetic resonance imaging as a biomarker for the pharmacological response of PTK787/ZK 222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases, in patients with advanced colorectal cancer and liver metastases: results from two phase I studies. J Clin Oncol 2003;21:3955-64.
    • (2003) J Clin Oncol , vol.21 , pp. 3955-3964
    • Morgan, B.1    Thomas, A.L.2    Drevs, J.3    Hennig, J.4    Buchert, M.5    Jivan, A.6
  • 15
    • 0642307227 scopus 로고    scopus 로고
    • Phase I trial of the antivascular agent combretastatin A4 phosphate on a 5-day schedule to patients with cancer: Magnetic resonance imaging evidence for altered tumor blood flow
    • Stevenson JP, Rosen M, Sun W, Gallagher M, Haller DG, Vaughn D, et al. Phase I trial of the antivascular agent combretastatin A4 phosphate on a 5-day schedule to patients with cancer: magnetic resonance imaging evidence for altered tumor blood flow. J Clin Oncol 2003;21:4428-38.
    • (2003) J Clin Oncol , vol.21 , pp. 4428-4438
    • Stevenson, J.P.1    Rosen, M.2    Sun, W.3    Gallagher, M.4    Haller, D.G.5    Vaughn, D.6
  • 16
    • 20444473802 scopus 로고    scopus 로고
    • Phase I clinical and pharmacokinetic study of PTK/ZK, a multiple VEGF receptor inhibitor, in patients with liver metastases from solid tumours
    • Mross K, Drevs J, Muller M, Medinger M, Marme D, Hennig J, et al. Phase I clinical and pharmacokinetic study of PTK/ZK, a multiple VEGF receptor inhibitor, in patients with liver metastases from solid tumours. Eur J Cancer 2005;41:1291-9.
    • (2005) Eur J Cancer , vol.41 , pp. 1291-1299
    • Mross, K.1    Drevs, J.2    Muller, M.3    Medinger, M.4    Marme, D.5    Hennig, J.6
  • 17
    • 23044432756 scopus 로고    scopus 로고
    • Phase I study of the safety, tolerability, pharmacokinetics, and pharmacodynamics of PTK787/ZK 222584 administered twice daily in patients with advanced cancer
    • Thomas AL, Morgan B, Horsfield MA, Higginson A, Kay A, Lee L, et al. Phase I study of the safety, tolerability, pharmacokinetics, and pharmacodynamics of PTK787/ZK 222584 administered twice daily in patients with advanced cancer. J Clin Oncol 2005;23:4162-71.
    • (2005) J Clin Oncol , vol.23 , pp. 4162-4171
    • Thomas, A.L.1    Morgan, B.2    Horsfield, M.A.3    Higginson, A.4    Kay, A.5    Lee, L.6
  • 18
    • 13844319702 scopus 로고    scopus 로고
    • Molecular imaging of antiangiogenic agents
    • Rehman S, Jayson GC. Molecular imaging of antiangiogenic agents. Oncologist 2005;10:92-103.
    • (2005) Oncologist , vol.10 , pp. 92-103
    • Rehman, S.1    Jayson, G.C.2
  • 19
    • 33846553852 scopus 로고    scopus 로고
    • Applications of dynamic contrast-enhanced MRI in oncology drug development
    • Jackson A, Parker GJM, Buckley DL, editors, Berlin: Springer-Verlag
    • Jayson G, Waterton JC. Applications of dynamic contrast-enhanced MRI in oncology drug development. In: Jackson A, Parker GJM, Buckley DL, editors. Dynamic contrast-enhanced magnetic resonance imaging in oncology. Berlin: Springer-Verlag, 2005:281-97.
    • (2005) Dynamic contrast-enhanced magnetic resonance imaging in oncology , pp. 281-297
    • Jayson, G.1    Waterton, J.C.2
  • 20
    • 34250778970 scopus 로고    scopus 로고
    • Imaging tumor vascular heterogeneity and angiogenesis using dynamic contrast-enhanced magnetic resonance imaging
    • Jackson A, O'Connor JP, Parker GJ, Jayson GC. Imaging tumor vascular heterogeneity and angiogenesis using dynamic contrast-enhanced magnetic resonance imaging. Clin Cancer Res 2007;13:3449-59.
    • (2007) Clin Cancer Res , vol.13 , pp. 3449-3459
    • Jackson, A.1    O'Connor, J.P.2    Parker, G.J.3    Jayson, G.C.4
  • 21
    • 33846478656 scopus 로고    scopus 로고
    • DCE-MRI biomarkers in the clinical evaluation of antiangiogenic and vascular disrupting agents
    • O'Connor JP, Jackson A, Parker GJ, Jayson GC. DCE-MRI biomarkers in the clinical evaluation of antiangiogenic and vascular disrupting agents. Br J Cancer 2007;96:189-95.
    • (2007) Br J Cancer , vol.96 , pp. 189-195
    • O'Connor, J.P.1    Jackson, A.2    Parker, G.J.3    Jayson, G.C.4
  • 25
    • 20044396551 scopus 로고    scopus 로고
    • Blockade of platelet-derived growth factor receptor-beta by CDP860, a humanized, PEGylated di-Fab′, leads to fluid accumulation and is associated with increased tumor vascularized volume
    • Jayson GC, Parker GJM, Mullamitha S, Valle JW, Saunders M, Broughton L, et al. Blockade of platelet-derived growth factor receptor-beta by CDP860, a humanized, PEGylated di-Fab′, leads to fluid accumulation and is associated with increased tumor vascularized volume. J Clin Oncol 2005;23:973-81.
    • (2005) J Clin Oncol , vol.23 , pp. 973-981
    • Jayson, G.C.1    Parker, G.J.M.2    Mullamitha, S.3    Valle, J.W.4    Saunders, M.5    Broughton, L.6
  • 26
    • 33644863001 scopus 로고    scopus 로고
    • Antiangiogenic and antitumor effects of bevacizumab in patients with inflammatory and locally advanced breast cancer
    • Wedam SB, Low JA, Yang SX, Chow CK, Choyke P, Danforth D, et al. Antiangiogenic and antitumor effects of bevacizumab in patients with inflammatory and locally advanced breast cancer. J Clin Oncol 2006;24:769-77.
    • (2006) J Clin Oncol , vol.24 , pp. 769-777
    • Wedam, S.B.1    Low, J.A.2    Yang, S.X.3    Chow, C.K.4    Choyke, P.5    Danforth, D.6
  • 27
    • 20244376908 scopus 로고    scopus 로고
    • Progress and promise of FDG-PET imaging for cancer patient management and oncologic drug development
    • Kelloff GJ, Hoffman JM, Johnson B, Scher HI, Siegel BA, Cheng EY, et al. Progress and promise of FDG-PET imaging for cancer patient management and oncologic drug development. Clin Cancer Res 2005;11:2785-808.
    • (2005) Clin Cancer Res , vol.11 , pp. 2785-2808
    • Kelloff, G.J.1    Hoffman, J.M.2    Johnson, B.3    Scher, H.I.4    Siegel, B.A.5    Cheng, E.Y.6
  • 28
    • 0041984595 scopus 로고    scopus 로고
    • 18FDG-positron emission tomography for the early prediction of response in advanced soft tissue sarcoma treated with imatinib mesylate (Glivec)
    • Stroobants S, Goeminne J, Seegers M, Dimitrijevic S, Dupont P, Nuyts J, et al. 18FDG-positron emission tomography for the early prediction of response in advanced soft tissue sarcoma treated with imatinib mesylate (Glivec). Eur J Cancer 2003;39:2012-20.
    • (2003) Eur J Cancer , vol.39 , pp. 2012-2020
    • Stroobants, S.1    Goeminne, J.2    Seegers, M.3    Dimitrijevic, S.4    Dupont, P.5    Nuyts, J.6
  • 29
    • 0142212381 scopus 로고    scopus 로고
    • PET imaging with 18F-FLT and thymidine analogs: Promise and pitfalls
    • Shields AF. PET imaging with 18F-FLT and thymidine analogs: promise and pitfalls. J Nucl Med 2003;44:1432-4.
    • (2003) J Nucl Med , vol.44 , pp. 1432-1434
    • Shields, A.F.1
  • 30
    • 9944248171 scopus 로고    scopus 로고
    • Measuring tumor pharmacodynamic response using PET proliferation probes: The case for 2-[(11)C]-thymidine
    • Wells P, West C, Jones T, Harris A, Price P. Measuring tumor pharmacodynamic response using PET proliferation probes: the case for 2-[(11)C]-thymidine. Biochim Biophy Acta 2004;2:91-102.
    • (2004) Biochim Biophy Acta , vol.2 , pp. 91-102
    • Wells, P.1    West, C.2    Jones, T.3    Harris, A.4    Price, P.5
  • 31
    • 32944479631 scopus 로고    scopus 로고
    • Molecular imaging in the development of cancer therapeutics
    • Czernin J, Weber WA, Herschman HR. Molecular imaging in the development of cancer therapeutics. Annu Rev Med 2006;57:99-118.
    • (2006) Annu Rev Med , vol.57 , pp. 99-118
    • Czernin, J.1    Weber, W.A.2    Herschman, H.R.3
  • 33
    • 4444383332 scopus 로고    scopus 로고
    • Receptor imaging in oncology by means of nuclear medicine: Current status
    • Van Den Bossche B, Van de Wiele C. Receptor imaging in oncology by means of nuclear medicine: current status. J Clin Oncol 2004;22:3593-607.
    • (2004) J Clin Oncol , vol.22 , pp. 3593-3607
    • Van Den Bossche, B.1    Van de Wiele, C.2
  • 34
    • 33745564266 scopus 로고    scopus 로고
    • Chaperoning drug development with PET
    • Weber WA. Chaperoning drug development with PET. J Nucl Med 2006;47:735-7.
    • (2006) J Nucl Med , vol.47 , pp. 735-737
    • Weber, W.A.1
  • 35
    • 33745955010 scopus 로고    scopus 로고
    • Positron emission tomography as an imaging biomarker
    • Weber WA. Positron emission tomography as an imaging biomarker. J Clin Oncol 2006;24:3282-92.
    • (2006) J Clin Oncol , vol.24 , pp. 3282-3292
    • Weber, W.A.1
  • 38
    • 0037183247 scopus 로고    scopus 로고
    • Diffusion MRI for prediction of response of rectal cancer to chemoradiation
    • Dzik-Jurasz A, Domenig C, George M, Wolber J, Padhani A, Brown G, et al. Diffusion MRI for prediction of response of rectal cancer to chemoradiation. Lancet 2002;360:307-8.
    • (2002) Lancet , vol.360 , pp. 307-308
    • Dzik-Jurasz, A.1    Domenig, C.2    George, M.3    Wolber, J.4    Padhani, A.5    Brown, G.6
  • 39
    • 0035394313 scopus 로고    scopus 로고
    • Monitoring response to convection-enhanced taxol delivery in brain tumor patients using diffusion-weighted magnetic resonance imaging
    • Mardor Y, Roth Y, Lidar Z, Jonas T, Pfeffer R, Maier SE, et al. Monitoring response to convection-enhanced taxol delivery in brain tumor patients using diffusion-weighted magnetic resonance imaging. Cancer Res 2001;61:4971-3.
    • (2001) Cancer Res , vol.61 , pp. 4971-4973
    • Mardor, Y.1    Roth, Y.2    Lidar, Z.3    Jonas, T.4    Pfeffer, R.5    Maier, S.E.6
  • 40
    • 0034652156 scopus 로고    scopus 로고
    • Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy
    • Chinnaiyan AM, Prasad U, Shankar S, Hamstra DA, Shanaiah M, Chenevert TL, et al. Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy. Proc Natl Acad Sci USA 2000;97:1754-9.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 1754-1759
    • Chinnaiyan, A.M.1    Prasad, U.2    Shankar, S.3    Hamstra, D.A.4    Shanaiah, M.5    Chenevert, T.L.6
  • 41
    • 33846149645 scopus 로고    scopus 로고
    • AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients
    • Batchelor TT, Sorensen AG, di Tomaso E, Zhang WT, Duda DG, Cohen KS, et al. AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients. Cancer Cell 2007;11:83-95.
    • (2007) Cancer Cell , vol.11 , pp. 83-95
    • Batchelor, T.T.1    Sorensen, A.G.2    di Tomaso, E.3    Zhang, W.T.4    Duda, D.G.5    Cohen, K.S.6
  • 42
    • 0037986306 scopus 로고    scopus 로고
    • End points and United States Food and Drug Administration approval of oncology drugs
    • Johnson JR, Williams G, Pazdur R. End points and United States Food and Drug Administration approval of oncology drugs. J Clin Oncol 2003;21:1404-11.
    • (2003) J Clin Oncol , vol.21 , pp. 1404-1411
    • Johnson, J.R.1    Williams, G.2    Pazdur, R.3
  • 44
    • 0036177190 scopus 로고    scopus 로고
    • Hepatic haemodynamics: Interrelationships between contrast enhancement and perfusion on CT and Doppler perfusion indices
    • Fuentes MA, Keith CJ, Griffiths M, Durbridge G, Miles KA. Hepatic haemodynamics: interrelationships between contrast enhancement and perfusion on CT and Doppler perfusion indices. Br J Radiol 2002;75:17-23.
    • (2002) Br J Radiol , vol.75 , pp. 17-23
    • Fuentes, M.A.1    Keith, C.J.2    Griffiths, M.3    Durbridge, G.4    Miles, K.A.5
  • 45
    • 0034913780 scopus 로고    scopus 로고
    • Standardized perfusion value: Universal ct contrast enhancement scale that correlates with FDG PET in lung nodules
    • Miles KA, GriffithsMR, Fuentes MA. Standardized perfusion value: universal ct contrast enhancement scale that correlates with FDG PET in lung nodules. Radiology 2001;220:548-53.
    • (2001) Radiology , vol.220 , pp. 548-553
    • Miles, K.A.1    Griffiths, M.R.2    Fuentes, M.A.3
  • 46
    • 33750613637 scopus 로고    scopus 로고
    • Experimentally-derived functional form for a population-averaged high-temporal-resolution arterial input function for dynamic contrast-enhanced MRI
    • Parker GJ, Roberts C, Macdonald A, Buonaccorsi GA, Cheung S, Buckley DL, et al. Experimentally-derived functional form for a population-averaged high-temporal-resolution arterial input function for dynamic contrast-enhanced MRI. Magn Reson Med 2006;56:993-1000.
    • (2006) Magn Reson Med , vol.56 , pp. 993-1000
    • Parker, G.J.1    Roberts, C.2    Macdonald, A.3    Buonaccorsi, G.A.4    Cheung, S.5    Buckley, D.L.6
  • 47
    • 33645665698 scopus 로고    scopus 로고
    • Comparative study into the robustness of compartmental modeling and model-free analysis in DCE-MRI studies
    • Roberts C, Issa B, Stone A, Jackson A, Waterton JC, Parker GJ. Comparative study into the robustness of compartmental modeling and model-free analysis in DCE-MRI studies. J Magn Reson Imaging 2006;23:554-63.
    • (2006) J Magn Reson Imaging , vol.23 , pp. 554-563
    • Roberts, C.1    Issa, B.2    Stone, A.3    Jackson, A.4    Waterton, J.C.5    Parker, G.J.6
  • 48
    • 0033738008 scopus 로고    scopus 로고
    • Quantitative assessment of tumor metabolism using FDG-PET imaging
    • Weber WA, Schwaiger M, Avril N. Quantitative assessment of tumor metabolism using FDG-PET imaging. Nucl Med Biol 2000;27:683-7.
    • (2000) Nucl Med Biol , vol.27 , pp. 683-687
    • Weber, W.A.1    Schwaiger, M.2    Avril, N.3
  • 49
    • 0036193478 scopus 로고    scopus 로고
    • Breath-hold perfusion and permeability mapping of hepatic malignancies using magnetic resonance imaging and a first-pass leakage profile model
    • Jackson A, Haroon H, Zhu XP, Li KL, Thacker NA, Jayson G. Breath-hold perfusion and permeability mapping of hepatic malignancies using magnetic resonance imaging and a first-pass leakage profile model. NMR Biomed 2002;15:164-73.
    • (2002) NMR Biomed , vol.15 , pp. 164-173
    • Jackson, A.1    Haroon, H.2    Zhu, X.P.3    Li, K.L.4    Thacker, N.A.5    Jayson, G.6
  • 50
    • 0038368018 scopus 로고    scopus 로고
    • Reproducibility of quantitative dynamic contrast-enhanced MRI in newly presenting glioma
    • Jackson A, Jayson GC, Li KL, Zhu XP, Checkley DR, Tessier JJ, et al. Reproducibility of quantitative dynamic contrast-enhanced MRI in newly presenting glioma. Br J Radiol 2003;76:153-62.
    • (2003) Br J Radiol , vol.76 , pp. 153-162
    • Jackson, A.1    Jayson, G.C.2    Li, K.L.3    Zhu, X.P.4    Checkley, D.R.5    Tessier, J.J.6
  • 51
    • 2942623549 scopus 로고    scopus 로고
    • Angiographic power 3-dimensional quantitative analysis in gynecologic solid tumors: Feasibility and reproducibility
    • Testa AC, Mansueto D, Lorusso D, Fruscella E, Basso D, Scambia G, et al. Angiographic power 3-dimensional quantitative analysis in gynecologic solid tumors: feasibility and reproducibility. J Ultrasound Med 2004;23:821-8.
    • (2004) J Ultrasound Med , vol.23 , pp. 821-828
    • Testa, A.C.1    Mansueto, D.2    Lorusso, D.3    Fruscella, E.4    Basso, D.5    Scambia, G.6
  • 52
    • 31344445418 scopus 로고    scopus 로고
    • A unifying approach for surrogate marker validation based on Prentice's criteria
    • Alonso A, Molenberghs G, Geys H, Buyse M, Vangeneugden T. A unifying approach for surrogate marker validation based on Prentice's criteria. Stat Med 2006;25:205-21.
    • (2006) Stat Med , vol.25 , pp. 205-221
    • Alonso, A.1    Molenberghs, G.2    Geys, H.3    Buyse, M.4    Vangeneugden, T.5
  • 54
    • 0024520844 scopus 로고
    • Surrogate endpoints in clinical trials: Definition and operational criteria
    • Prentice R. Surrogate endpoints in clinical trials: definition and operational criteria. Stat Med 1989;8:431-40.
    • (1989) Stat Med , vol.8 , pp. 431-440
    • Prentice, R.1
  • 55
    • 31344434774 scopus 로고    scopus 로고
    • Statistical evaluation of biomarkers as surrogate endpoints: A literature review
    • Weir CJ, Walley RJ. Statistical evaluation of biomarkers as surrogate endpoints: a literature review. Stat Med 2006;25:183-203.
    • (2006) Stat Med , vol.25 , pp. 183-203
    • Weir, C.J.1    Walley, R.J.2
  • 56
    • 51349098660 scopus 로고    scopus 로고
    • FDA Critical Path Initiative, Available from:, Accessed 30 April 2008
    • FDA Critical Path Initiative. US Food and Drug Administration. Available from: http://www.fda.gov/oc/initiatives/criticalpath [Accessed 30 April 2008].
  • 57
    • 33845974419 scopus 로고    scopus 로고
    • Biomarkers and surrogate end points for fit-for-purpose development and regulatory evaluation of new drugs
    • Wagner JA, Williams SA, Webster CJ. Biomarkers and surrogate end points for fit-for-purpose development and regulatory evaluation of new drugs. Clin Pharmacol Ther 2007;81:104-7,
    • (2007) Clin Pharmacol Ther , vol.81 , pp. 104-107
    • Wagner, J.A.1    Williams, S.A.2    Webster, C.J.3
  • 58
    • 33750515034 scopus 로고    scopus 로고
    • A cost-effectiveness approach to the qualification and acceptance of biomarkers
    • Williams SA, Slavin DE, Wagner JA, Webster CJ. A cost-effectiveness approach to the qualification and acceptance of biomarkers. Nat Rev Drug Discov 2006;5:897-902.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 897-902
    • Williams, S.A.1    Slavin, D.E.2    Wagner, J.A.3    Webster, C.J.4
  • 60
    • 0038352143 scopus 로고    scopus 로고
    • Interobserver and intraobserver variability in measurement of non-small-cell carcinoma lung lesions: Implications for assessment of tumor response
    • Erasmus JJ, Gladish GW, Broemeling L, Sabloff BS, Truong MT, Herbst RS, et al. Interobserver and intraobserver variability in measurement of non-small-cell carcinoma lung lesions: implications for assessment of tumor response. J Clin Oncol 2003;21:2574-82.
    • (2003) J Clin Oncol , vol.21 , pp. 2574-2582
    • Erasmus, J.J.1    Gladish, G.W.2    Broemeling, L.3    Sabloff, B.S.4    Truong, M.T.5    Herbst, R.S.6
  • 61
    • 33847159680 scopus 로고    scopus 로고
    • Quantification of FDG PET studies using standardised uptake values in multi-centre trials: Effects of image reconstruction, resolution and ROI definition parameters
    • Westerterp M, Pruim J, Oyen W, Hoekstra O, Paans A, Visser E, et al. Quantification of FDG PET studies using standardised uptake values in multi-centre trials: effects of image reconstruction, resolution and ROI definition parameters. Eur J Nucl Med Mol Imaging 2007;34:392-404.
    • (2007) Eur J Nucl Med Mol Imaging , vol.34 , pp. 392-404
    • Westerterp, M.1    Pruim, J.2    Oyen, W.3    Hoekstra, O.4    Paans, A.5    Visser, E.6
  • 62
    • 8844249275 scopus 로고    scopus 로고
    • Assessment of antiangiogenic and antivascular therapeutics using MRI: Recommendations for appropriate methodology for clinical trials
    • Leach MO, Brindle KM, Evelhoch JL, Griffiths JR, Horsman MR, Jackson A, et al. Assessment of antiangiogenic and antivascular therapeutics using MRI: recommendations for appropriate methodology for clinical trials. Br J Radiol 2003;76:S87-91.
    • (2003) Br J Radiol , vol.76
    • Leach, M.O.1    Brindle, K.M.2    Evelhoch, J.L.3    Griffiths, J.R.4    Horsman, M.R.5    Jackson, A.6
  • 63
    • 23844456531 scopus 로고    scopus 로고
    • Expanding the use of magnetic resonance in the assessment of tumor response to therapy: Workshop report
    • Evelhoch J, Garwood M, Vigneron D, Knopp M, Sullivan D, Menkens A, et al. Expanding the use of magnetic resonance in the assessment of tumor response to therapy: workshop report. Cancer Res 2005;65:7041-4.
    • (2005) Cancer Res , vol.65 , pp. 7041-7044
    • Evelhoch, J.1    Garwood, M.2    Vigneron, D.3    Knopp, M.4    Sullivan, D.5    Menkens, A.6
  • 65
    • 0038016615 scopus 로고    scopus 로고
    • On the development of rational standards for nuclear response evaluation
    • Laking GR, Price PM. On the development of rational standards for nuclear response evaluation. Q J Nucl Med 2003;47:3-7.
    • (2003) Q J Nucl Med , vol.47 , pp. 3-7
    • Laking, G.R.1    Price, P.M.2
  • 66
    • 0032757213 scopus 로고    scopus 로고
    • Measurement of clinical and subclinical tumour response using [18F]-fluorodeoxyglucose and positron emission tomography: Review and 1999 EORTC recommendations
    • Young H, Baum R, Cremerius U, Herholz K, Hoekstra O, Lammertsma AA, et al. Measurement of clinical and subclinical tumour response using [18F]-fluorodeoxyglucose and positron emission tomography: review and 1999 EORTC recommendations. Eur J Cancer 1999;35:1773-82.
    • (1999) Eur J Cancer , vol.35 , pp. 1773-1782
    • Young, H.1    Baum, R.2    Cremerius, U.3    Herholz, K.4    Hoekstra, O.5    Lammertsma, A.A.6
  • 67
    • 33746036112 scopus 로고    scopus 로고
    • Consensus recommendations for the use of 18F-FDG PET as an indicator of therapeutic response in patients in National Cancer Institute trials
    • Shankar LK, Hoffman JM, Bacharach S, Graham MM, Karp J, Lammertsma AA, et al. Consensus recommendations for the use of 18F-FDG PET as an indicator of therapeutic response in patients in National Cancer Institute trials. J Nucl Med 2006;47:1059-66.
    • (2006) J Nucl Med , vol.47 , pp. 1059-1066
    • Shankar, L.K.1    Hoffman, J.M.2    Bacharach, S.3    Graham, M.M.4    Karp, J.5    Lammertsma, A.A.6
  • 68


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.