Breath-hold perfusion and permeability mapping of hepatic malignancies using magnetic resonance imaging and a first-pass leakage profile model

NMR in Biomedicine

Volumn 15, Issue 2, 2002, Pages 164-173

  Jackson, A ^a,c   Haroon, H ^a   Zhu, X P ^a   Li, K L ^a   Thacker, N A ^a   Jayson, G ^b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b CHRISTIE HOSPITAL   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Dynamic MRI; Endothelial permeability; Liver neoplasm; Perfusion; Pharmacokinetic model

Indexed keywords

BLOOD; IMAGE PROCESSING; MEDICAL APPLICATIONS; TISSUE;

NEOPLASMS;

BIOMEDICAL ENGINEERING;

GADODIAMIDE; NUCLEAR MAGNETIC RESONANCE IMAGING AGENT;

ADULT; AGED; ARTICLE; BLOOD VOLUME; BREATH HOLDING; CLINICAL ARTICLE; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DRUG CONCENTRATION; DRUG DISTRIBUTION; FEMALE; FIRST PASS EFFECT; HEPATIC ARTERY; HUMAN; INFORMATION PROCESSING; LIVER CANCER; LIVER CIRCULATION; LIVER PERFUSION; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PERMEABILITY; PORTAL VEIN BLOOD FLOW; PRIORITY JOURNAL; REPRODUCIBILITY; STATISTICS; VASCULAR ENDOTHELIUM;

ADENOCARCINOMA; ADULT; AGED; BLOOD VESSELS; COLORECTAL NEOPLASMS; CONTRAST MEDIA; FEMALE; GADOLINIUM DTPA; HEMANGIOMA, CAVERNOUS; HUMANS; INHALATION; LIVER NEOPLASMS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PERMEABILITY; REPRODUCIBILITY OF RESULTS;

EID: 0036193478     PISSN: 09523480     EISSN: None     Source Type: Journal    
DOI: 10.1002/nbm.729     Document Type: Article

References (33)

1. Introduction
2. Vascular endothelial growth factor: A key mediator of neoangiogenesis. A review
3. Assessing tumor angiogenesis using macromolecular MR imaging contrast media
4. Non-invasive vascular imaging: Assessing tumour vascularity
5. Echo-planar MR cerebral blood volume mapping of gliomas. Clinical utility
6. Tumor angiogenesis- A new therapeutic target in gliomas
7. Angiogenesis in the pathobiology and treatment of vascular and malignant diseases
8. Improved 3D quantitative mapping of blood volume and endothelial permeability in brain tumors
9. * contrast-enhanced dynamic MR
10. Modeling tracer kinetics in dynamic Gd-DTPA MR imaging
11. Pharmacokinetic parameters in CNS Gd-DTPA enhanced MR imaging
12. Quantitation of blood-brain carrier defect by magnetic resonance imaging and gadolinium-DTPA in patients with multiple sclerosis and brain tumors
13. MRI in focal liver disease: A comparison of small and ultra-small superparamagnetic iron oxide as hepatic contrast agents
14. Detection of hepaticmetastasis: Feromoxides-enhanced MR imaging versus unenhanced MRI imaging and CT during arterial portography
15. Assessment of hepatic perfusion in pigs by pharmacokinetic analysis of dynamic MR images
16. Multiphase hepatic CT with a multirow detector CT scanner
17. Improved quality of re-sliced MR images using re-normalized sinc interpolation
18. Measurement of the blood brain barrier permeability and leakage space using dynamic MR imaging: Fundamental concepts
19. Intraclass correlations: A two-facet case study and some comments on the concept of reliability
20. Measurement error and correlation coefficients
21. Estimating kinetic parameters from dynamic contrast-enhanced T(1)- weighted MRI of a diffusable tracer: Standardized quantities and symbols
22. Regional blood flow, capillary permeability, and compartmental volumes: Measurement with dynamic CT-initial experience
23. Uterine cervical carcinoma: Comparison of standard and pharmacokinetic analysis of time-intensity curve for assessment of tumor angiogenesis and patient survival
24. MR imaging of tumor microcirculation: Promise for the new millennium
25. Quantification of myocardial blood flow and extracellular volumes using a bolus injection of Gd-DTPA: Kinetic modeling in canine ischemic disease
26. Measurement of the extraction efficiency and distribution volume for Gd-DTPA in normal and diseased canine myocardium
27. Studies of Gd-DTPA relaxivity and proton exchange rates in tissue
28. Pitfalls in the measurement of tissue permeability over short time-scales using a low temporal resolution blood input function
29. The impact of the arterial input function (AIF) on quantitative evaluation of dynamic susceptibility contrast enhanced MR studies
30. Improving estimates of endothelial permeability surface area product using constrained fitting parameters for the estimation of the plasma tracer concentration function (PTCF)
31. 1 mapping by means of fast field echo technique
32. Maximum likelihood from incomplete data via the EM algorithm