-
1
-
-
33747375880
-
B-Raf is critical for MAPK activation during mitosis and is regulated in an M phase-dependent manner in Xenopus egg extracts
-
Borysov, S. I., Cheng, A. W., and Guadagno, T. M. (2006). B-Raf is critical for MAPK activation during mitosis and is regulated in an M phase-dependent manner in Xenopus egg extracts. J. Biol. Chem. 281, 22586-22596.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 22586-22596
-
-
Borysov, S.I.1
Cheng, A.W.2
Guadagno, T.M.3
-
2
-
-
0035163367
-
Cyclin B/cdc2 induces c-Mos stability by direct phosphorylation in Xenopus oocytes
-
Castro, A., Peter, M., Magnaghi-Jaulin, L., Vigneron, S., Galas, S., Lorca, T., and Labbe, J. C. (2001). Cyclin B/cdc2 induces c-Mos stability by direct phosphorylation in Xenopus oocytes. Mol. Biol. Cell 12, 2660-2671.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 2660-2671
-
-
Castro, A.1
Peter, M.2
Magnaghi-Jaulin, L.3
Vigneron, S.4
Galas, S.5
Lorca, T.6
Labbe, J.C.7
-
3
-
-
0027945787
-
Partial purification of a mitogen-activated protein kinase kinase activator from bovine brain. Identification as B-Raf or a B-Raf-associated activity
-
Catling, A. D., Reuter, C. W., Cox, M. E., Parsons, S. J., and Weber, M. J. (1994). Partial purification of a mitogen-activated protein kinase kinase activator from bovine brain. Identification as B-Raf or a B-Raf-associated activity. J. Biol. Chem. 269, 30014-30021.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 30014-30021
-
-
Catling, A.D.1
Reuter, C.W.2
Cox, M.E.3
Parsons, S.J.4
Weber, M.J.5
-
4
-
-
0037400510
-
Mechanisms of regulating the Raf kinase family
-
Chong, H., Vikis, H. G., and Guan, K. L. (2003). Mechanisms of regulating the Raf kinase family. Cell Signal 15, 463-469.
-
(2003)
Cell Signal
, vol.15
, pp. 463-469
-
-
Chong, H.1
Vikis, H.G.2
Guan, K.L.3
-
5
-
-
43749087380
-
B-Raf(V600E) signaling deregulates the mitotic spindle checkpoint through stabilizing Mps1 levels in melanoma cells
-
Cui, Y., and Guadagno, T. M. (2007). B-Raf(V600E) signaling deregulates the mitotic spindle checkpoint through stabilizing Mps1 levels in melanoma cells. Oncogene 27, 3122-3133.
-
(2007)
Oncogene
, vol.27
, pp. 3122-3133
-
-
Cui, Y.1
Guadagno, T.M.2
-
6
-
-
0028104204
-
The ins and outs of Raf kinases
-
Daum, G., Eisenmann-Tappe, I., Fries, H. W., Troppmair, J., and Rapp, U. R. (1994). The ins and outs of Raf kinases. Trends Biochem. Sci. 19, 474-480.
-
(1994)
Trends Biochem. Sci
, vol.19
, pp. 474-480
-
-
Daum, G.1
Eisenmann-Tappe, I.2
Fries, H.W.3
Troppmair, J.4
Rapp, U.R.5
-
7
-
-
0035076221
-
Thrombopoietin-mediated sustained activation of extracellular signal-regulated kinase in UT7-Mpl cells requires both Ras-Raf-1- and Rap1-B-Raf-dependent pathways
-
Garcia, J., de Gunzburg, J., Eychene, A., Gisselbrecht, S., and Porteu, F. (2001). Thrombopoietin-mediated sustained activation of extracellular signal-regulated kinase in UT7-Mpl cells requires both Ras-Raf-1- and Rap1-B-Raf-dependent pathways. Mol. Cell Biol. 21, 2659-2670.
-
(2001)
Mol. Cell Biol
, vol.21
, pp. 2659-2670
-
-
Garcia, J.1
de Gunzburg, J.2
Eychene, A.3
Gisselbrecht, S.4
Porteu, F.5
-
8
-
-
0032514880
-
Requirement for MAPK activation for normal mitotic progression in Xenopus egg extracts
-
Guadagno, T. M., and Ferrell, J. E., Jr. (1998). Requirement for MAPK activation for normal mitotic progression in Xenopus egg extracts. Science 282, 1312-1315.
-
(1998)
Science
, vol.282
, pp. 1312-1315
-
-
Guadagno, T.M.1
Ferrell Jr., J.E.2
-
9
-
-
0034282892
-
Negative regulation of the serine/threonine kinase B-Raf by Akt
-
Guan, K. L., Figueroa, C., Brtva, T. R., Zhu, T., Taylor, J., Barber, T. D., and Vojtek, A. B. (2000). Negative regulation of the serine/threonine kinase B-Raf by Akt. J. Biol. Chem. 275, 27354-27359.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 27354-27359
-
-
Guan, K.L.1
Figueroa, C.2
Brtva, T.R.3
Zhu, T.4
Taylor, J.5
Barber, T.D.6
Vojtek, A.B.7
-
10
-
-
0033604576
-
Isotype-specific functions of Raf kinases
-
Hagemann, C., and Rapp, U. R. (1999). Isotype-specific functions of Raf kinases. Exp. Cell Res. 253, 34-46.
-
(1999)
Exp. Cell Res
, vol.253
, pp. 34-46
-
-
Hagemann, C.1
Rapp, U.R.2
-
11
-
-
0037815498
-
A requirement for MAP kinase in the assembly and maintenance of the mitotic spindle
-
Horne, M. M., and Guadagno, T. M. (2003). A requirement for MAP kinase in the assembly and maintenance of the mitotic spindle. J. Cell Biol. 161, 1021-1028.
-
(2003)
J. Cell Biol
, vol.161
, pp. 1021-1028
-
-
Horne, M.M.1
Guadagno, T.M.2
-
12
-
-
17744378364
-
MEK kinase activity is not necessary for Raf-1 function
-
Huser, M., Luckett, J., Chiloeches, A., Mercer, K., Iwobi, M., Giblett, S., Sun, X. M., Brown, J., Marais, R., and Pritchard, C. (2001). MEK kinase activity is not necessary for Raf-1 function. EMBO J. 20, 1940-1951.
-
(2001)
EMBO J
, vol.20
, pp. 1940-1951
-
-
Huser, M.1
Luckett, J.2
Chiloeches, A.3
Mercer, K.4
Iwobi, M.5
Giblett, S.6
Sun, X.M.7
Brown, J.8
Marais, R.9
Pritchard, C.10
-
13
-
-
0037322744
-
Active cyclin B1-Cdk1 first appears on centrosomes in prophase
-
Jackman, M., Lindon, C., Nigg, E. A., and Pines, J. (2003). Active cyclin B1-Cdk1 first appears on centrosomes in prophase. Nat. Cell Biol. 5, 143-148.
-
(2003)
Nat. Cell Biol
, vol.5
, pp. 143-148
-
-
Jackman, M.1
Lindon, C.2
Nigg, E.A.3
Pines, J.4
-
14
-
-
0028031527
-
The mitogen-activated protein kinase cascade is activated by B-Raf in response to nerve growth factor through interaction with p21ras
-
Jaiswal, R. K., Moodie, S. A., Wolfman, A., and Landreth, G. E. (1994). The mitogen-activated protein kinase cascade is activated by B-Raf in response to nerve growth factor through interaction with p21ras. Mol. Cell. Biol. 14, 6944-6953.
-
(1994)
Mol. Cell. Biol
, vol.14
, pp. 6944-6953
-
-
Jaiswal, R.K.1
Moodie, S.A.2
Wolfman, A.3
Landreth, G.E.4
-
15
-
-
0034667593
-
Meaningful relationships: The regulation of the Ras/Raf/MEK/ERK pathway by protein interactions
-
Kolch, W. (2000). Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions. Biochem. J. 351(Pt 2), 289-305.
-
(2000)
Biochem. J
, vol.351
, Issue.PART 2
, pp. 289-305
-
-
Kolch, W.1
-
16
-
-
0343238874
-
Expression of the A-raf proto-oncogene in the normal adult and embryonic mouse
-
Luckett, J. C., Huser, M. B., Giagtzoglou, N., Brown, J. E., and Pritchard, C. A. (2000). Expression of the A-raf proto-oncogene in the normal adult and embryonic mouse. Cell Growth Differ. 11, 163-171.
-
(2000)
Cell Growth Differ
, vol.11
, pp. 163-171
-
-
Luckett, J.C.1
Huser, M.B.2
Giagtzoglou, N.3
Brown, J.E.4
Pritchard, C.A.5
-
17
-
-
0031041171
-
Differential regulation of Raf-1, A-Raf, and B-Raf by oncogenic ras and tyrosine kinases
-
Marais, R., Light, Y., Paterson, H. F., Mason, C. S., and Marshall, C. J. (1997). Differential regulation of Raf-1, A-Raf, and B-Raf by oncogenic ras and tyrosine kinases. J. Biol. Chem. 272, 4378-4383.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 4378-4383
-
-
Marais, R.1
Light, Y.2
Paterson, H.F.3
Mason, C.S.4
Marshall, C.J.5
-
18
-
-
0033561041
-
Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation
-
Mason, C. S., Springer, C. J., Cooper, R. G., Superti-Furga, G., Marshall, C. J., and Marais, R. (1999). Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation. EMBO J. 18, 2137-2148.
-
(1999)
EMBO J
, vol.18
, pp. 2137-2148
-
-
Mason, C.S.1
Springer, C.J.2
Cooper, R.G.3
Superti-Furga, G.4
Marshall, C.J.5
Marais, R.6
-
19
-
-
0038697566
-
Raf proteins and cancer: B-Raf is identified as a mutational target
-
Mercer, K. E., and Pritchard, C. A. (2003). Raf proteins and cancer: B-Raf is identified as a mutational target. Biochim. Biophys. Acta 1653, 25-40.
-
(2003)
Biochim. Biophys. Acta
, vol.1653
, pp. 25-40
-
-
Mercer, K.E.1
Pritchard, C.A.2
-
20
-
-
0028134981
-
A MAP kinase-dependent spindle assembly checkpoint in Xenopus egg extracts
-
Minshull, J., Sun, H., Tonks, N. K., and Murray, A. W. (1994). A MAP kinase-dependent spindle assembly checkpoint in Xenopus egg extracts. Cell 79, 475-486.
-
(1994)
Cell
, vol.79
, pp. 475-486
-
-
Minshull, J.1
Sun, H.2
Tonks, N.K.3
Murray, A.W.4
-
22
-
-
0026266161
-
Cell cycle extracts
-
Murray, A. W. (1991). Cell cycle extracts. Methods Cell Biol. 36, 581-605.
-
(1991)
Methods Cell Biol
, vol.36
, pp. 581-605
-
-
Murray, A.W.1
-
23
-
-
0026207389
-
The substrates of the cdc2 kinase
-
Nigg, E. A. (1991). The substrates of the cdc2 kinase. Semin. Cell Biol. 2, 261-270.
-
(1991)
Semin. Cell Biol
, vol.2
, pp. 261-270
-
-
Nigg, E.A.1
-
24
-
-
0030048696
-
Activation of brain B-Raf protein kinase by Rap1B small GTP-binding protein
-
Ohtsuka, T., Shimizu, K., Yamamori, B., Kuroda, S., and Takai, Y. (1996). Activation of brain B-Raf protein kinase by Rap1B small GTP-binding protein. J. Biol. Chem. 271, 1258-1261.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 1258-1261
-
-
Ohtsuka, T.1
Shimizu, K.2
Yamamori, B.3
Kuroda, S.4
Takai, Y.5
-
25
-
-
0032544525
-
Modulation of kinase activity and oncogenic properties by alternative splicing reveals a novel regulatory mechanism for B-Raf
-
Papin, C., Denouel-Galy, A., Laugier, D., Calothy, G., and Eychene, A. (1998). Modulation of kinase activity and oncogenic properties by alternative splicing reveals a novel regulatory mechanism for B-Raf. J. Biol. Chem. 273, 24939-24947.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 24939-24947
-
-
Papin, C.1
Denouel-Galy, A.2
Laugier, D.3
Calothy, G.4
Eychene, A.5
-
26
-
-
0030133927
-
Post-natal lethality and neurological and gastrointestinal defects in mice with targeted disruption of the A-Raf protein kinase gene
-
Pritchard, C. A., Bolin, L., Slattery, R., Murray, R., and McMahon, M. (1996). Post-natal lethality and neurological and gastrointestinal defects in mice with targeted disruption of the A-Raf protein kinase gene. Curr. Biol. 6, 614-617.
-
(1996)
Curr. Biol
, vol.6
, pp. 614-617
-
-
Pritchard, C.A.1
Bolin, L.2
Slattery, R.3
Murray, R.4
McMahon, M.5
-
27
-
-
0025572606
-
p34cdc2 kinase is localized to distinct domains within the mitotic apparatus
-
Rattner, J. B., Lew, J., and Wang, J. H. (1990). p34cdc2 kinase is localized to distinct domains within the mitotic apparatus. Cell Motil. Cytoskelet. 17, 227-235.
-
(1990)
Cell Motil. Cytoskelet
, vol.17
, pp. 227-235
-
-
Rattner, J.B.1
Lew, J.2
Wang, J.H.3
-
28
-
-
0028965111
-
Biochemical analysis of MEK activation in NIH3T3 fibroblasts. Identification of B-Raf and other activators
-
Reuter, C. W., Catling, A. D., Jelinek, T., and Weber, M. J. (1995). Biochemical analysis of MEK activation in NIH3T3 fibroblasts. Identification of B-Raf and other activators. J. Biol. Chem. 270, 7644-7655.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 7644-7655
-
-
Reuter, C.W.1
Catling, A.D.2
Jelinek, T.3
Weber, M.J.4
-
29
-
-
0024573538
-
The cdc2 kinase is a nuclear protein that is essential for mitosis in mammalian cells
-
Riabowol, K., Draetta, G., Brizuela, L., Vandre, D., and Beach, D. (1989). The cdc2 kinase is a nuclear protein that is essential for mitosis in mammalian cells. Cell 57, 393-401.
-
(1989)
Cell
, vol.57
, pp. 393-401
-
-
Riabowol, K.1
Draetta, G.2
Brizuela, L.3
Vandre, D.4
Beach, D.5
-
30
-
-
0033848878
-
Integrating the MAP kinase signal into the G1 phase cell cycle machinery
-
Roovers, K., and Assoian, R. K. (2000). Integrating the MAP kinase signal into the G1 phase cell cycle machinery. Bioessays 22, 818-826.
-
(2000)
Bioessays
, vol.22
, pp. 818-826
-
-
Roovers, K.1
Assoian, R.K.2
-
31
-
-
3042536038
-
Preclinical and clinical development of the cyclin-dependent kinase inhibitor flavopiridol
-
Shapiro, G. I. (2004). Preclinical and clinical development of the cyclin-dependent kinase inhibitor flavopiridol. Clin. Cancer Res. 10, 4270s-4275s.
-
(2004)
Clin. Cancer Res
, vol.10
-
-
Shapiro, G.I.1
-
32
-
-
0025266334
-
Expression of raf family proto-oncogenes in normal mouse tissues
-
Storm, S. M., Cleveland, J. L., and Rapp, U. R. (1990). Expression of raf family proto-oncogenes in normal mouse tissues. Oncogene 5, 345-351.
-
(1990)
Oncogene
, vol.5
, pp. 345-351
-
-
Storm, S.M.1
Cleveland, J.L.2
Rapp, U.R.3
-
33
-
-
0030898893
-
MAP kinase is required for the spindle assembly checkpoint but is dispensable for the normal M phase entry and exit in Xenopus egg cell cycle extracts
-
Takenaka, K., Gotoh, Y., and Nishida, E. (1997). MAP kinase is required for the spindle assembly checkpoint but is dispensable for the normal M phase entry and exit in Xenopus egg cell cycle extracts. J. Cell Biol. 136, 1091-1097.
-
(1997)
J. Cell Biol
, vol.136
, pp. 1091-1097
-
-
Takenaka, K.1
Gotoh, Y.2
Nishida, E.3
-
34
-
-
18144373477
-
B-Raf and Raf-1 are regulated by distinct autoregulatory mechanisms
-
Tran, N. H., Wu, X., and Frost, J. A. (2005). B-Raf and Raf-1 are regulated by distinct autoregulatory mechanisms. J. Biol. Chem. 280, 16244-16253.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 16244-16253
-
-
Tran, N.H.1
Wu, X.2
Frost, J.A.3
-
35
-
-
0030963439
-
cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway
-
Vossler, M. R., Yao, H., York, R. D., Pan, M. G., Rim, C. S., and Stork, P. J. (1997). cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway. Cell 89, 73-82.
-
(1997)
Cell
, vol.89
, pp. 73-82
-
-
Vossler, M.R.1
Yao, H.2
York, R.D.3
Pan, M.G.4
Rim, C.S.5
Stork, P.J.6
-
36
-
-
0037294545
-
Phosphorylation of the cyclin b1 cytoplasmic retention sequence by mitogen-activated protein kinase and Plx
-
Walsh, S., Margolis, S. S., and Kornbluth, S. (2003). Phosphorylation of the cyclin b1 cytoplasmic retention sequence by mitogen-activated protein kinase and Plx. Mol. Cancer Res. 1, 280-289.
-
(2003)
Mol. Cancer Res
, vol.1
, pp. 280-289
-
-
Walsh, S.1
Margolis, S.S.2
Kornbluth, S.3
-
37
-
-
0344647981
-
A role for mitogen-activated protein kinase in the spindle assembly checkpoint in XTC cells
-
Wang, X. M., Zhai, Y., and Ferrell, J. E., Jr. (1997). A role for mitogen-activated protein kinase in the spindle assembly checkpoint in XTC cells. J. Cell Biol. 137, 433-443.
-
(1997)
J. Cell Biol
, vol.137
, pp. 433-443
-
-
Wang, X.M.1
Zhai, Y.2
Ferrell Jr., J.E.3
-
38
-
-
0025913050
-
Independent inactivation of MPF and cytostatic factor (Mos) upon fertilization of Xenopus eggs
-
Watanabe, N., Hunt, T., Ikawa, Y., and Sagata, N. (1991). Independent inactivation of MPF and cytostatic factor (Mos) upon fertilization of Xenopus eggs. Nature 352, 247-248.
-
(1991)
Nature
, vol.352
, pp. 247-248
-
-
Watanabe, N.1
Hunt, T.2
Ikawa, Y.3
Sagata, N.4
-
39
-
-
0024326801
-
Specific proteolysis of the c-mos proto-oncogene product by calpain on fertilization of Xenopus eggs
-
Watanabe, N., Vande Woude, G. F., Ikawa, Y., and Sagata, N. (1989). Specific proteolysis of the c-mos proto-oncogene product by calpain on fertilization of Xenopus eggs. Nature 342, 505-511.
-
(1989)
Nature
, vol.342
, pp. 505-511
-
-
Watanabe, N.1
Vande Woude, G.F.2
Ikawa, Y.3
Sagata, N.4
-
40
-
-
8444238236
-
The RAF proteins take centre stage
-
Wellbrock, C., Karasarides, M., and Marais, R. (2004). The RAF proteins take centre stage. Nat. Rev. Mol. Cell Biol. 5, 875-885.
-
(2004)
Nat. Rev. Mol. Cell Biol
, vol.5
, pp. 875-885
-
-
Wellbrock, C.1
Karasarides, M.2
Marais, R.3
-
41
-
-
0033997943
-
Overlapping and specific functions of Braf and Craf-1 proto-oncogenes during mouse embryogenesis
-
Wojnowski, L., Stancato, L. F., Larner, A. C., Rapp, U. R., and Zimmer, A. (2000). Overlapping and specific functions of Braf and Craf-1 proto-oncogenes during mouse embryogenesis. Mech. Dev. 91, 97-104.
-
(2000)
Mech. Dev
, vol.91
, pp. 97-104
-
-
Wojnowski, L.1
Stancato, L.F.2
Larner, A.C.3
Rapp, U.R.4
Zimmer, A.5
-
42
-
-
0032143608
-
Craf-1 protein kinase is essential for mouse development
-
Wojnowski, L., Stancato, L. F., Zimmer, A. M., Hahn, H., Beck, T. W., Larner, A. C., Rapp, U. R., and Zimmer, A. (1998). Craf-1 protein kinase is essential for mouse development. Mech. Dev. 76, 141-149.
-
(1998)
Mech. Dev
, vol.76
, pp. 141-149
-
-
Wojnowski, L.1
Stancato, L.F.2
Zimmer, A.M.3
Hahn, H.4
Beck, T.W.5
Larner, A.C.6
Rapp, U.R.7
Zimmer, A.8
-
43
-
-
0030977312
-
Endothelial apoptosis in Braf-deficient mice
-
Wojnowski, L., Zimmer, A. M., Beck, T. W., Hahn, H., Bernal, R., Rapp, U. R., and Zimmer, A. (1997). Endothelial apoptosis in Braf-deficient mice. Nat. Genet. 16, 293-297.
-
(1997)
Nat. Genet
, vol.16
, pp. 293-297
-
-
Wojnowski, L.1
Zimmer, A.M.2
Beck, T.W.3
Hahn, H.4
Bernal, R.5
Rapp, U.R.6
Zimmer, A.7
-
44
-
-
4644345203
-
Mos mediates the mitotic activation of p42 MAPK in Xenopus egg extracts
-
Yue, J., and Ferrell, J. E., Jr. (2004). Mos mediates the mitotic activation of p42 MAPK in Xenopus egg extracts. Curr. Biol. 14, 1581-1586.
-
(2004)
Curr. Biol
, vol.14
, pp. 1581-1586
-
-
Yue, J.1
Ferrell Jr., J.E.2
-
45
-
-
33745806589
-
Mechanistic studies of the mitotic activation of mos
-
Yue, J., and Ferrell, J. E., Jr. (2006). Mechanistic studies of the mitotic activation of mos. Mol. Cell Biol. 26, 5300-5309.
-
(2006)
Mol. Cell Biol
, vol.26
, pp. 5300-5309
-
-
Yue, J.1
Ferrell Jr., J.E.2
-
46
-
-
0034675919
-
Activation of B-Raf kinase requires phosphorylation of the conserved residues Thr598 and Ser601
-
Zhang, B. H., and Guan, K. L. (2000). Activation of B-Raf kinase requires phosphorylation of the conserved residues Thr598 and Ser601. EMBO J. 19, 5429-5439.
-
(2000)
EMBO J
, vol.19
, pp. 5429-5439
-
-
Zhang, B.H.1
Guan, K.L.2
-
47
-
-
0035087327
-
Regulation of the Raf kinase by phosphorylation
-
Zhang, B. H., and Guan, K. L. (2001). Regulation of the Raf kinase by phosphorylation. Exp. Lung Res. 27, 269-295.
-
(2001)
Exp. Lung Res
, vol.27
, pp. 269-295
-
-
Zhang, B.H.1
Guan, K.L.2
-
48
-
-
33750611606
-
Mps1 phosphorylation by MAP kinase is required for kinetochore localization of spindle-checkpoint proteins
-
Zhao, Y., and Chen, R. H. (2006). Mps1 phosphorylation by MAP kinase is required for kinetochore localization of spindle-checkpoint proteins. Curr. Biol. 16, 1764-1769.
-
(2006)
Curr. Biol
, vol.16
, pp. 1764-1769
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-
Zhao, Y.1
Chen, R.H.2
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