Expression patterns of neurotrophins and neurotrophin receptors in articular chondrocytes and inflammatory infiltrates in knee joint arthritis

Cells Tissues Organs

Volumn 188, Issue 3, 2008, Pages 299-309

  Grimsholm, Ola ^a   Guo, Yongzhi ^a   Ny, Tor ^a   Forsgren, Sture ^a  

^a UMEÅ UNIVERSITY   (Sweden)

Author keywords

Arthritis; Articular chondrocytes; Nerve growth factor; Neurotrophins; p75; Rheumatoid arthritis

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; NERVE GROWTH FACTOR; NEUROTROPHIN; NEUROTROPHIN RECEPTOR; NEUROTROPHIN RECEPTOR P75; PROTEIN TYROSINE KINASE A;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; CARTILAGE CELL; CONTROLLED STUDY; DISEASE SEVERITY; IMMUNOREACTIVITY; INFLAMMATION; INFLAMMATORY INFILTRATE; KNEE ARTHRITIS; MALE; MOUSE; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR DOWN REGULATION; SYNOVIUM;

ANIMALS; ARTHRITIS, EXPERIMENTAL; CARTILAGE, ARTICULAR; CHONDROCYTES; IMMUNOHISTOCHEMISTRY; INFLAMMATION; KNEE JOINT; MALE; MICE; NERVE GROWTH FACTORS; RECEPTORS, NERVE GROWTH FACTOR;

MUS;

EID: 51349129595     PISSN: 14226405     EISSN: None     Source Type: Journal    
DOI: 10.1159/000121432     Document Type: Article

References (35)

1. Aloe, L., M.A. Tuveri, U. Carcassi, R. Levi-Montalcini (1992) Nerve growth factor in the synovial fluid of patients with chronic arthritis. Arthritis Rheum 35: 351-355.
2. Aloe, L., L. Probert, G. Kollias, L. Bracci-Laudiero, A. Micera, C. Mollinari, R. Levi-Montalcini (1993) Level of nerve growth factor and distribution of mast cells in the synovium of tumour necrosis factor transgenic arthritic mice. Int J Tissue React 15: 139-143.
3. Aloe, L., L. Probert, G. Kollias, A. Micera, P. Tirassa (1995) Effect of NGF antibodies on mast cell distribution, histamine and substance P levels in the knee joint of TNF-arthritic transgenic mice. Rheumatol Int 14: 249-252.
4. Aloe, L., L. Bracci-Laudiero, S. Bonini, L. Manni (1997) The expanding role of nerve growth factor: from neurotrophic activity to immunologic diseases. Allergy 52: 883-894.
5. Aloe, L. (2004) Nerve growth factor, human skin ulcers and vascularization. Our experience. Prog Brain Res 146: 515-522.
6. Asaumi, K., T. Nakanishi, H. Asahara, H. Inoue, M. Takigawa (2000) Expression of neurotrophins and their receptors (TRK) during fracture healing. Bone 26: 625-633.
7. Baier, A., I. Meineckel, S. Gay, T. Pap (2003) Apoptosis in rheumatoid arthritis. Curr Opin Rheumatol 15: 274-279.
8. Bracci-Laudiero, L., L. Aloe, P. Buanne, A. Finn, C. Stenfors, E. Vigneti, E. Theodorsson, T. Lundeberg (2002) NGF modulates CGRP synthesis in human B-lymphocytes: a possible anti-inflammatory action of NGF? J Neuroimmunol 123: 58-65.
9. Chao, M.V., B.L. Hempstead (1995) p75 and Trk: a two-receptor system. Trends Neurosci 18: 321-326.
10. Chapman, B.S., I.D. Kuntz (1995) Modeled structure of the 75-kDa neurotrophin receptor. Protein Sci 4: 1696-1707.
11. Funakoshi, H., J. Frisen, G. Barbany, T. Timmusk, O. Zachrisson, V.M. Verge, H. Persson (1993) Differential expression of mRNAs for neurotrophins and their receptors after axotomy of the sciatic nerve. J Cell Biol 123: 455-465.
12. Gigante, A., C. Bevilacqua, A. Pagnotta, S. Manzotti, A. Toesca, F. Greco (2003) Expression of NGF, TrkA and p75 in human cartilage. Eur J Histochem 47: 339-344.
13. Halliday, D.A., C. Zettler, R.A. Rush, R. Scicchitano, J.D. McNeil (1998) Elevated nerve growth factor levels in the synovial fluid of patients with inflammatory joint disease. Neurochem Res 23: 919-922.
14. Hansson, M., S. Forsgren (1995) Immunoreactive atrial and brain natriuretic peptides are co-localized in Purkinje fibres but not in the innervation of the bovine heart conduction system. Histochem J 27: 222-230.
15. Iannone, F., C. De Bari, F. Dell'Accio, M. Covelli, V. Patella, G. Lo Bianco, G. Lapadula (2002) Increased expression of nerve growth factor (NGF) and high affinity NGF receptor (p140 TrkA) in human osteoarthritic chondrocytes. Rheumatology (Oxford) 41: 1413-1418.
16. Johnson, D., A. Lanahan, C.R. Buck, A. Sehgal, C. Morgan, E. Mercer, M. Bothwell, M. Chao (1986) Expression and structure of the human NGF receptor. Cell 47: 545-554.
17. Lambiase, A., L. Bracci-Laudiero, S. Bonini, G. Starace, M.M. D'Elios, M. De Carli, L. Aloe (1997) Human CD4+ T cell clones produce and release nerve growth factor and express high-affinity nerve growth factor receptors. J Allergy Clin Immunol 100: 408-414.
18. Levi-Montalcini, R. (1987) The nerve growth factor 35 years later. Science 237: 1154-1162.
19. Li, J., Y. Guo, R. Holmdahl, T. Ny (2005) Contrasting roles of plasminogen deficiency in different rheumatoid arthritis models. Arthritis Rheum 52: 2541-2548.
20. Linnarsson, S., C.A. Willson, P. Ernfors (2000) Cell death in regenerating populations of neurons in BDNF mutant mice. Brain Res Mol Brain Res 75: 61-69.
21. Manni, L., L. Aloe (1998) Role of IL-1 beta and TNF-alpha in the regulation of NGF in experimentally induced arthritis in mice. Rheumatol Int 18: 97-102.
22. Manni, L., T. Lundeberg, S. Fiorito, S. Bonini, E. Vigneti, L. Aloe (2003) Nerve growth factor release by human synovial fibroblasts prior to and following exposure to tumor necrosis factor-alpha, interleukin-1 beta and cholecystokinin-8: the possible role of NGF in the inflammatory response. Clin Exp Rheumatol 21: 617-624.
23. Martin-Zanca, D., R. Oskam, G. Mitra, T. Copeland, M. Barbacid (1989) Molecular and biochemical characterization of the human trk proto-oncogene. Mol Cell Biol 9: 24-33.
24. Muangman, P., L.A. Muffley, J.P. Anthony, M.L. Spenny, R.A. Underwood, J.E. Olerud, N.S. Gibran (2004) Nerve growth factor accelerates wound healing in diabetic mice. Wound Repair Regen 12: 44-52.
25. Myers, L.K., E.F. Rosloniec, M.A. Cremer, A.H. Kang (1997) Collagen-induced arthritis, an animal model of autoimmunity. Life Sci 61: 1861-1878.
26. Nockher, W.A., H. Renz (2005) Neurotrophins in clinical diagnostics: pathophysiology and laboratory investigation. Clin Chim Acta 352: 49-74.
27. Noga, O., C. Englmann, G. Hanf, A. Grutzkau, S. Guhl, G. Kunkel (2002) Activation of the specific neurotrophin receptors TrkA, TrkB and TrkC influences the function of eosinophils. Clin Exp Allergy 32: 1348-1354.
28. Persson-Sjogren, S., D. Holmberg, S. Forsgren (2005) Remodeling of the innervation of pancreatic islets accompanies insulitis preceding onset of diabetes in the NOD mouse. J Neuroimmunol 158: 128-137.
29. Rannou, F., M. Francois, M.T. Corvol, F. Berenbaum (2006) Cartilage breakdown in rheumatoid arthritis. Joint Bone Spine 73: 29-36.
30. Rihl, M., E. Kruithof, C. Barthel, F. De Keyser, E.M. Veys, H. Zeidler, D.T. Yu, J.G. Kuipers, D. Baeten (2005) Involvement of neurotrophins and their receptors in spondyloarthritis synovitis: relation to inflammation and response to therapy. Ann Rheum Dis 64: 1542-1549.
31. Verge, V.M., P.M. Richardson, Z. Wiesenfeld-Hallin, T. Hokfelt (1995) Differential influence of nerve growth factor on neuropeptide expression in vivo: a novel role in peptide suppression in adult sensory neurons. J Neurosci 15: 2081-2096.
32. Weidler, C., C. Holzer, M. Harbuz, R. Hofbauer, P. Angele, J. Scholmerich, R.H. Straub (2005) Low density of sympathetic nerve fibres and increased density of brain derived neurotrophic factor positive cells in RA synovium. Ann Rheum Dis 64: 13-20.
33. Wu, Z., K. Nagata, T. Iijima (2000) Immunohistochemical study of NGF and its receptors in the synovial membrane of the ankle joint of adjuvant-induced arthritic rats. Histochem Cell Biol 114: 453-459.
34. Yamashiro, T., T. Fukunaga, K. Yamashita, N. Kobashi, T. Takano-Yamamoto (2001) Gene and protein expression of brain-derived neurotrophic factor and TrkB in bone and cartilage. Bone 28: 404-409.
35. Zhu, Z., H. Friess, X. Shi, L. Wang, F.F. di Mola, M. Wirtz, M. Hartel, M. Wagner, A. Zimmermann, M. Muller, M.W. Buchler (2003) Up-regulation of p75 neurotrophin receptor (p75NTR) is associated with apoptosis in chronic pancreatitis. Dig Dis Sci 48: 717-725.