NGF modulates CGRP synthesis in human B-lymphocytes: A possible anti-inflammatory action of NGF?

Journal of Neuroimmunology

Volumn 123, Issue 1-2, 2002, Pages 58-65

  Bracci Laudiero, Luisa ^a,b   Aloe, Luigi ^b   Buanne, Pasquale ^b   Finn, Anja ^a   Stenfors, Carina ^a   Vigneti, Eliana ^b   Theodorsson, Elvar ^c   Lundeberg, Thomas ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b CNR   (Italy)

^c LINKÖPING UNIVERSITY   (Sweden)

Author keywords

Neuroimmunology; Neurotrophins; Sensory neuropeptides

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR ANTIBODY;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; B LYMPHOCYTE; CELL ACTIVATION; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; NERVE CELL; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN SECRETION; REGULATORY MECHANISM; SENSORY NERVE CELL;

ANTI-INFLAMMATORY AGENTS; B-LYMPHOCYTES; CALCITONIN GENE-RELATED PEPTIDE; CELLS, CULTURED; HUMANS; NERVE GROWTH FACTOR; RNA, MESSENGER;

EID: 0036190573     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(01)00475-1     Document Type: Article

References (71)

1. Capsaicin effects on substance P and CGRP in rat adjuvant arthritis
2. Nerve growth factor in the synovial fluid of patients with chronic arthritis
3. The expanding role of nerve growth factor: From neurotrophic activity to immunologic diseases
4. Inhibition of the induction of delayed-type and contact hypersensitivity by calcitonin gene-related peptide
5. Specific induction of cAMP in Langherals cells by calcitonin gene-related peptide: Relevance to functional effects
6. Neuropeptide innervation of lymphoid organs
7. Bilateral changes of substance P neurokinin A, calcitonin gene related peptide and neuropeptide Y immunoreactivity in rat knee joint synovial fluid during acute monoarthritis
8. The nerve growth factor: Purification as a 30,000-molecular-weight protein
9. Multiple sclerosis patients express increased levels of β-nerve growth factor in cerebrospinal fluid
10. Increased levels of NGF in sera of systemic lupus erythematosus patients
11. Functional nerve growth factor receptors on human B-lymphocytes. Interaction with IL-2
12. Selective regulation of T-cell development and function by calcitonin gene-related peptide in thymus and spleen. An example of differential regional regulation of immunity by the neuroendocrine system
13. Effects of capsaicin in temporomandibular joint arthritis in rats
14. Calcitonin gene-related peptide decreases expression of HLA-DR and CD86 by human dendritic cells and dampens dendritic cell-driven T cell-proliferative responses via the type I calcitonin gene-related peptide receptor
15. Sensory denervation with capsaicin attenuates inflammation and nociception in arthritic rats
16. Human B-lymphocyte subpopulations: I. Differentiation of density-separated B-lymphocytes
17. Expression of nerve growth factor and nerve growth factor receptor tyrosine kinase Trk in activated CD4-positive T-cell clones
18. Primary sensory afferents in the thymus of the guinea pig demonstrated with anterogradely transported horseradish peroxidase conjugates
19. Splenic primary sensory afferents in the guinea pig demonstrated with anterogradely transported wheat-germ agglutinin conjugated to horseradish peroxidase
20. Noradrenergic and peptidergic innervation of secondary lymphoid organs: Role in experimental rheumatoid arthritis
21. Calcitonin-gene related peptide (CGRP) inhibits interleukin-7-induced pre-B-cell colony formation
22. Calcitonin gene-related peptide inhibits proliferation and antigen presentation by human peripheral blood mononuclear cells: Effects on B7, interleukin 10, and interleukin 12
23. Biological importance of the retrograde transport of nerve growth factor in sensory neurons
24. A quantitative bioassay for nerve growth factor (NGF) activity employing a clonal pheochromocytoma cell line
25. Regulation of Langherans cell function by nerves containing calcitonin gene-related peptide
26. Alternative RNA processing events in human calcitonin/calcitonin gene-related peptide gene expression
27. Differential effects of neuropeptides on cytokin production by mouse helper T cell subsets
28. Nerve growth factor specifically induces human IgG4 production
29. Human lymphocytes express SP and their receptors
30. Human CD4+ T-clones produce and release nerve growth factor and express TrkA
31. Concentration of substance P, neurokinin A, calcitonin gene-related peptide, neuropeptide Y and vasoactive intestinal polypeptide in synovial fluid from knee joints in patients suffering from rheumatoid arthritis
32. Expression of mRNA encoding neurotrophins and neurotrophin receptors in rat thymus, spleen tissue and immunocompetent cells
33. The nerve growth factor 35 years later
34. A role for nerve growth factor in nervous, endocrine and immune systems
35. Intraneuronal substance P contributes to the severity of experimental arthritis
36. Contribution of sensory afferents and sympathetic efferents to joint injury in experimental arthritis
37. Neuropeptides by direct interaction with T cells induce cytokine secretion and break the commitment to a distinct T helper phenotype
38. Nerve growth factor regulates expression of neuropeptide genes in adult sensory neurones
39. Characterization of functional calcitonin gene-related peptide receptors on rat lymphocytes
40. Modulation of B-lymphocyte differentiation by calcitonin gene-related peptide (CGRP): I. Characterization of high-affinity CGRP receptors on murine 70Z/3 cells
41. Modulation of B-lymphocyte differentiation by calcitonin gene-related peptide (CGRP): II. Inhibition of LPS-induced kappa light chain expression by CGRP
42. A role for CGRP in the regulation of early lymphocyte differentiation
43. Nerve growth factor signal transduction in human B-lymphocyte is mediated by gp140 trk
44. Nerve growth factor antibody exacerbates neuropathological signs of experimental allergic encephalomyelitis in adult Lewis rats
45. Characterization of a calcitonin gene related peptide (CGRP) receptor on mouse bone marrow cells
46. Binding sites of calcitonin gene-related peptide (CGRP): Abundant occurrence in visceral organs
47. Structure and expression of a gene encoding human calcitonin and calcitonin gene related peptide
48. Neurotrophins inhibit major histocompatibility class II inducibility of microglia: Involvement of the p75 neurotrophin receptor
49. Peptides encoded by the calcitonin gene inhibit macrophage function
50. Nerve growth factor induces growth and differentiation of human B-lymphocytes
51. The role of neuropeptides in inflammation
52. The localization of sensory nerve fibers and receptor binding sites for sensory neuropeptides in canine mesenteric lymph nodes
53. Potent anti-inflammatory action of calcitonin gene-related peptide
54. Action of sensory neurons in a experimental reat colitis model of injury and repair
55. Calcitonin gene-related peptide mediates the protective effect of sensory nerves in a model of colonic injury
56. Nerve growth factor production by lymphocytes
57. Neuropeptides: Mediators of inflammation and tissue repair?
58. A second human calcitonin/CGRP gene
59. Effect of calcitonin gene-related peptide and vasoactive intestinal peptide on murine CD4 and CD8 T cell proliferation
60. The influence of nerve growth factor on the in vitro proliferative response of rat spleen lymphocytes
61. Receptors for nerve growth factor on rat spleen mononuclear cells
62. Nerve growth factor is an autocrine survival factor for memory B-lymphocytes
63. Characterization of the calcitonin gene-related peptide receptor in mouse T lymphocytes
64. Inhibition of mitogen-stimulated T lymphocyte proliferation by calcitonin gene-related peptide
65. Differential influence of nerve growth factor on neuropeptide expression in vivo: A novel role in peptide suppression in adult sensory neurons
66. Macrophages express functional receptors for calcitonin-gene-related peptide
67. Human nerve growth factor protects common marmosets against autoimmune encephalomyelitis by switching the balance of T helper cell type 1 and 2 cytokines within the central nervous system
68. Calcitonin gene-releted peptide inhibits interleukin 2 production by murine T lymphocytes
69. Identification and characterization of immunoreactive calcitonin gene-related peptide from lymphocytes of the rat
70. Neurotrophins and the anti-inflammatory agents interleukin-4 (IL-4), IL-10, IL-11 and transforming growth factor-beta1 (TGF-beta1) down-regulate T cell costimulatory molecules B7 and CD40 on cultured rat microglia
71. Immunoreactive calcitonin gene-related peptide and substance P coexist in sensory neuron to the spinal cord and interact in spinal behavioural responses of the rat