Palifermin mediates immunoregulatory effects in addition to its cytoprotective effects in mice with acute graft-versus-host disease

Journal of Clinical Immunology

Volumn 28, Issue 5, 2008, Pages 600-615

  Ellison, Cynthia A ^a,b   Makar, Bryce M ^a   Wiseman, Jacqie M M ^a   Gheorghiu, Ionela ^a   Taniguchi, Masaru ^c   Gartner, John G ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

^b Manitoba Blood and Marrow Transplant Program   (Canada)

^c RIKEN Center for Integrative Medical Sciences   (Japan)

Author keywords

Cytokines; Graft versus host disease; Hematopoietic stem cell transplantation; Keratinocyte growth factor; Th1 Th2

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 13; INTERLEUKIN 15; INTERLEUKIN 4; MESSENGER RNA; PALIFERMIN; THYMIC STROMAL LYMPHOPOIETIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACUTE GRAFT VERSUS HOST DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; C57BL 6 MOUSE; CELL PROTECTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DBA 2 MOUSE; DONOR; DRUG EFFECT; FEMALE; GRAFT RECIPIENT; IMMUNOREGULATION; MORBIDITY; MOUSE; NATURAL KILLER T CELL; NONHUMAN; PRIORITY JOURNAL; SURVIVAL; TH2 CELL; THYMUS; WEIGHT REDUCTION;

ACUTE DISEASE; ANIMALS; CELL LINE, TRANSFORMED; CYTOKINES; EPITHELIAL CELLS; FIBROBLAST GROWTH FACTOR 7; GRAFT VS HOST DISEASE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; INJECTIONS, SUBCUTANEOUS; KILLER CELLS, NATURAL; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, KNOCKOUT; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 2; RECOMBINANT PROTEINS; TH1 CELLS; TH2 CELLS;

EID: 51349107721     PISSN: 02719142     EISSN: 15732592     Source Type: Journal    
DOI: 10.1007/s10875-008-9216-1     Document Type: Article

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