Keratinocyte growth factor administered before conditioning ameliorates graft-versus-host disease after allogeneic bone marrow transplantation in mice

Blood

Volumn 92, Issue 10, 1998, Pages 3960-3967

  Panoskaltsis Mortari, Angela ^a   Lacey, David L ^b   Vallera, Daniel A ^b   Blazar, Bruce R ^b  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHOSPHAMIDE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1; INTERLEUKIN 6; KERATINOCYTE GROWTH FACTOR;

ALLOGENIC BONE MARROW TRANSPLANTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; COHORT ANALYSIS; GRAFT VERSUS HOST REACTION; IRRADIATION; MORBIDITY; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIATION INJURY; STATISTICAL ANALYSIS; SURVIVAL RATE; TISSUE INJURY; TISSUE REPAIR; WOUND HEALING;

EID: 0032533233     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v92.10.3960.422k29_3960_3967     Document Type: Article

References (43)

1. Finch PW, Rubin SS, Miki T, Ron D, Aaronson SA: Human KGF is FGF-related with properties of a paracrine effector of epithelial growth. Science 245:752, 1989
2. Housley RM, Morris CF, Boyle W, Ring B, Blitz R, Tarpley JE, Aukerman SL, Devine PL, Whitehead RH, Pierce GF: Keratinocyte growth factor induces proliferation of hepatocytes and epithelial cells throughout the rat gastrointestinal tract. J Clin Invest 94:1767, 1994
3. Ulich TR, Yi ES, Longmuir K, Yin S, Blitz R, Morris CF, Housley RM, Pierce GF: Keratinocyte growth factor is a growth factor for type II pneumocytes in vivo, J Clin Invest 93:1298, 1994
4. Panos RJ, Rubin JS, Aaronson SA, Mason RJ: Keratinocyte growth factor and hepatocyte growth factor scatter factor are heparinbinding growth factors for alveolar type II cells in fibroblastconditioned medium. J Clin Invest 92:969, 1993
5. Yi ES, Williams ST, Lee H, Malicki DM, Chin EM, Yin S, Tarpley J, Ulich TR: Keratinocyte growth factor ameliorates radiation- and bleomycin-indueed lung injury and mortality. Am J Pathol 149:1963, 1996
6. Takeoka M, Ward WF, Pollack H, Kamp DW, Panos RJ: KGF facilitates repair of radiation-induced DNA damage in alveolar epitheliall cells, Am J Physiol 272 (Lung Cell Mol Physiol 16):L1174, 1997
7. Ulich TR, Whitcomb L, Tang W, O'Connor Tressel P, Tarpley J, Yi ES, Lacey D: Keratinocyte growth factor ameliorates cyclophosphamideinduced ulcerative hemorrhagic cystitis. Cancer Res 57:472, 1997
8. Farrell CL, Bready JV, Rex KL, Chen JN, DiPalma CR, Whitcomb KL, Yin S, Hill DC. Wiemann B, Starnes CO, Havill AM, Lu Z-N, Aukerman SL, Pierce GF, Thumason A, Potten CS, Ulich TR, Lacey DL: Keratinocyte growth factor protects mice from chemotherapy and radiation-induced gastrointestinal injury and mortality. Cancer Res 58:933, 1998
9. Khan WB, Shui C, Ning S, Knox SJ: Enhancement of murine intestinal stem cell survival after irradiation by keratinocyte growth factor. Radiat Res 148:248, 1997
10. Ning S, Shui C, Khan WB, Benson W, Lacey DL, Knox SJ: Effects of keratinocyte growth factor on the proliferation and radiation survival of human squamous cell carcinoma cell lines in vitro and in vivo. Int J Radiat Oncol Biol Phys 40:177, 1998
11. Rubin JS, Osada H, Finch PW, TaylorWG, Rudikoff S, Aaronson SA: Purification and characterization of a newly identified growth factor specific for epithelial cells. Proc Natl Acad Sci USA 86:802, 1989
12. Blazar BR, Taylor PA, Linsley PS, Vallera DA: In vivo blockade of CD28/CTLA4:B7/BB1 interaction with CTLA4-Ig reduces lethal m urine graft-vers us-host disease across the major histocompatibility complex (MHC) barrier in mice. Blood 83:3815, 1994
13. Blazar BR, Taylor PA, Snover DC, Bluestone JA, Vallera DA: Nonmitogenic anti-CD3F(ab')2 fragments inhibit lethal murine graft-versus-host disease induced across the major histocompatibility barrier. J Immunol 150:265, 1993
14. Rappaport H, Khalil A, Halle-Pannenko O, Pritchard L, Dantchev D, Mathe G: Histopathologic sequence of events in adult mice undergoing lethal graft-versus-host reaction developed across H-2 and/or non-H-2 histocompatibility barriers. Am J Pathol 96:121, 1979
15. Charley MR, Bangert JL, Hamilton BL, Gilliam JN, Sontheimer RD: Murine graft-versus-host skin disease: A chronologic and quantitative analysis of two histologic patterns. J Invest Dermatol 81:412, 1983
16. Yousem SA, Berry GJ, Brunt EM, Chamberlain D, Hruban RH, Sibley RK, Stewart S, Tazelaar HD: A working formulation for the standardization of nomenclature in the diagnosis of heart and lung rejection: lung rejection study group. J Heart Transplant 9:593, 1990
17. Bucy RP, Xu XY, Li J, Huang GQ: Cyclosporin A-induced autoimmune disease in mice. J Immunol 151:1039, 1993
18. Mowat A: Intestinal graft versus host disease, in Ferrara JLM, Deeg HJ, Burakoff SJ (eds): Graft-Versus-Host Disease. New York, NY, Marcel Dekker, 1997, p 337
19. Crawford JM: Graft-versus-host disease of the liver, in Ferrara JLM, Deeg HJ, Burakoff SJ (eds): Graft-Versus-Host Disease. New York, NY, Marcel Dekker, 1997, p 315
20. Mantel N: Evaluation of survival data and two new rank order statistics arising in its consideration. Cancer Chemother Rep 50:163, 1966
21. Soderling CCB, Song CW, Blazar BR, Vallera DA: A correlation between conditioning and engraftment in recipients of MHC-mismatched T cell-depleted murine bone marrow transplants. J Immunol 135:941, 1985
22. Panoskaltsis-Mortari A, Taylor PA, Yaeger TM, Wangensteen OD, Bitterman PB, Ingbar DH, Vallera DA, Blazar BR: The critical early proinflammatory events associated with idiopathic pneumonia syndrome in irradiated murine allogeneic recipients are due to donor T cell infusion and potentiated by cyclophosjphamide. J Clin Invest 100:1015, 1997
23. Pearson AE, Phelps TA: Radiation effects on mouse incisor teeth following whole-body doses of up to 16 Gray. Int J Radiat Biol 39:409, 1981
24. Down JD, Tarbell NJ, Warhol M, Mauch P: Dose-limiting complications from upper half body irradiation in C3H mice. Int J Rad Oncol Biol Phys 14:483, 1988
25. Danilenko DM, Ring BD, Yanagihara D, Benson W, Wiemann B, Starnes CO, Pierce GF: Keratinocyte growth factor is an important endogenous mediator of hair follicle growth, development and differentiation. Normalization of the nu/nu follicular differentiation defect and amelioration of the chemotherapy-induced alopecia. Am J Pathol 147:145, 1995
26. Zeeh JM, Procaccino F, Hoffmann P, Aukerman SL, McRoberts JA, Soltani S, Pierce GF, Lakshmanan J, Lacey D, Eysselein VE: Keratinocyte growth factor ameliorates mucosal injury in an experimental model of colitis in rats. Gastroenterology 110:1077, 1996
27. Blazar BR, Taylor PA, Panoskaltsis-Mortari A, Buhlman J, Xu J, Flavell RA, Korngold R, Noelle R, Vallera DA: Blockade of CD40 ligand:CD40 interaction impairs CD4+ T cell mediated alloreactivity by inhibiting mature donor T cell expansion and function after bone marrow transplantation. J Immunol 158:29, 1997
28. Blazar BR, Taylor PA, Boyer MB, Panoskaltsis-Mortari A, Gordon KB, Allison JP, Vallera DA: CD28/B7 interactions are required for sustaining the graft-versus-leukemia effect of delayed post-BMT splenocyte infusion in murine recipients of myeloid or lymphoid leukemia cells. J Immunol 159:3460, 1997
29. Blazar BR, Jenkins MK, Taylor PA, White J, Panoskaltsis-Mortari A, Korngold R, Vallera DA: Anti-CD3∈F(ab')2 fragments inhibit T cell expansion in vivo during graft-versus-host disease or the primary response to nominal antigen. J Immunol 159:5821, 1997
30. Li D-Q, Tseng SCG: Differential regulation of cytokine and receptor transcript expression in human corneal and limbal fibroblasts by epidermal growth factor, transforming growth factor-α. plateletderived growth factor B. and interleukin-1β. Invest Ophthalmol Vis Sci 37:2068, 1996
31. Boismenu R, Havran WL: Modulation of epithelial cell growth by intraepithelial γδ T cells. Science 266:1253, 1994
32. Rubin JS, Bottaro DP, Chedid M, Miki T, Ron D, Cheon HG, Taylor WG, Fortney E, Sakata H, Finch PW, LaRochelle WJ: Keratinocyte growth factor. Cell Biol Int 19:399, 1995
33. Mason IJ, Fuller-Pace F, Smith R, Dickson C: FGF-7 (keratinocyte growth factor) expression during mouse development suggests role in myogenesis, forebrain regionalisation and epithelial-mesenchymal interactions. Mech Dev 45:15, 1994
34. Finch PW, Cunha GR, Rubin JS, Wong J, Ron D: Pattern of keratinocyte growth factor and keratinoeyte growth factor receptor expression during mouse fetal development suggests a role in mediating morphogenetic mesenchymal-epithelial interactions. Dev Dynammics 203:223, 1995
35. Jaye M, Schlessinger J, Dionne CA: Fibroblast growth factor receptor tyrosine kinases: molecular analysis and signal transduction. Biochem Biophys Acta 1135:185, 1992
36. Shaoul E, Reich-Slotky R, Berman B, Ron D: Fibroblast growth factor receptors display both common and distinct signaling pathways. Oncogene 10:1553, 1995
37. Frank S, Muna B, Werner S: The human homologue of a bovine-non-selenium gkitathione peroxidase is a novel keratinocyte growth factor-regulated gene. Oncogene 14:915, 1997
38. Pierce GF, Yanagihara D, Klopchin K, Danilenko DM, Hsu E, Kenny WC, Morris CF: Stimulation of all epithelial elements during skin regeneration by keratinocyte growth factor. J Exp Med 179:831, 1994
39. Yi ES, Shabaik AS, Lacey DL, Bedoya AA, Yin S, Housley RM, Danilenko DM, Benson W, Cohen AM, Pierce GF, Thomason A, Ulich TR: Keratinocyte growth factor causes proliferation of urothelium in vivo. J Urol 154:1566, 1994
40. Yi ES, Yin S, Harclode D, Bedoya A, Bikhazi N, Housley RM, Aukerman SL, Morris CF, Pierce GF, Ulich TR: Keratinocyte growth factor induces pancreatic ductal epithelial proliferation. Am J Pathol 145:80, 1994
41. Ulich TR, Yi E, Cardiff R, Yin S, Bikhazi N, Biltz R, Morris F, Pierce G: Keratinocyte growth factor is a growth factor for mammary epithelium in vivo. Am J Pathol 144:862, 1994
42. Waters CM, Savla U, Panos RJ: KGF prevents hydrogen peroxide-induced increases in airway epithelial cell permeability. Am J Physiol 272 (Lung Cell Mol Physiol 16):L681, 1997
43. Drugan CS, Stone A, Game SM, Prime SS: The mitogenic effect of KGF and the expression of its cell surface receptor on cultured normal and malignant human oral keratinocytes and on contiguous fibroblasts. J Oral Pathol Med 26:327, 1997