The relationship between physicochemical characterization and the potential toxicity of fine particulates (PM2.5) in Shanghai atmosphere

Atmospheric Environment

Volumn 42, Issue 31, 2008, Pages 7205-7214

  Senlin, Lu ^a   Zhenkun, Yao ^a   Xiaohui, Chen ^a   Minghong, Wu ^a   Guoying, Sheng ^a   Jiamo, Fu ^a   Paul, Daly ^b  

^a SHANGHAI UNIVERSITY   (China)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Environmental scanning electron microscopy (ESEM); Inductively coupled plasma atomic mission spectrum (ICP AES); Plasmid DNA assay; Shanghai PM2.5; Toxicity

Indexed keywords

ENVIRONMENTAL SCANNING ELECTRON MICROSCOPY (ESEM); INDUCTIVELY COUPLED PLASMA ATOMIC MISSION SPECTRUM (ICP-AES); PLASMID DNA ASSAY; SHANGHAI PM2.5; TOXICITY;

PERMANENT MAGNETS;

ALUMINUM; ARSENIC; BARIUM; CADMIUM; CALCIUM; COAL; COPPER; IRON; LEAD; MAGNESIUM; MANGANESE; NICKEL; PLASMID DNA; POTASSIUM; SELENIUM; SODIUM; STRONTIUM; ZINC;

AERODYNAMICS; BIOASSAY; COAL; DNA; FLY ASH; HEAVY METAL; HUMAN ACTIVITY; INDUCTIVELY COUPLED PLASMA METHOD; MICROAGGREGATE; PARTICULATE MATTER; PHYSICOCHEMICAL PROPERTY; PLASMID; SCANNING ELECTRON MICROSCOPY; SEASONAL VARIATION; SOOT; SPRING (SEASON); SUBURBAN AREA; SYNERGISM; TOXICITY;

AIR POLLUTION; AIRBORNE PARTICLE; ARTICLE; ATOMIC EMISSION SPECTROMETRY; AUTUMN; CHINA; DNA DAMAGE; DNA DETERMINATION; ECOTOXICITY; ENRICHMENT FACTOR ANALYSIS; ENVIRONMENTAL SCANNING ELECTRON MICROSCOPY; FACTORIAL ANALYSIS; FLY ASH; NONHUMAN; PARTICLE SIZE; PARTICULATE MATTER; PHYSICAL CHEMISTRY; PILOT STUDY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SEASONAL VARIATION; SOOT; SPRING; STATISTICAL SIGNIFICANCE; SUMMER; URBAN AREA; WINTER;

ASIA; CHINA; EURASIA; FAR EAST; SHANGHAI;

EID: 51349101066     PISSN: 13522310     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atmosenv.2008.07.030     Document Type: Article

References (33)

1. Adamson I.Y.R., Prieditis H., Hedgecock C., and Vincent R. Zinc is the toxic factor in the lung response to an atmospheric particulate sample. Toxicology and Applied Pharmacology 166 (2000) 111-119
2. Chapman R.S., Watkinson W.P., Dreher K.L., and Costa D.L. Ambient particulate matter and respiratory and cardiovascular illness in adults: particle-borne transition metals and the heart-lung axis. Environmental Toxicology and Pharmacology 4 (1997) 331-338
3. Chang H., Yang S., and Dong J. Study on the element species of atmosphere aerosol. Environmental Chemistry 19 6 (2000) 485-499 (in Chinese)
4. Donaldson K., Beswick P.H., and Gilmour P.S. Free radical activity associated with the surface of particles: a unifying factor in determining biological activity?. Toxicology Letters (1996) 293-298
5. Donaldson K., Li X., and MacNee W. Ultrafine (nanometer) particle mediated lung injury. Journal of Aerosol Science 29 (1998) 553-560
6. 10). Free Radical Biological and Medicine 34 11 (2003) 1369-1382
7. 10: iron-mediated generation of hydroxyl radicals. Environmental Health Perspectives 105 (1997) 1285-1289
8. Derrick E. Smog Alarm (1999), Science Press, Beijing pp. 32-79 (in Chinese)
9. EPA. PM standards revision - 2006. Available from:.
10. Fu Q., Zhuang G., Wang J., Xu C., Huang K., Li J., Hou B., Lu T., and Streets D.G. Mechanism of formation of the heaviest pollution episode ever recorded in the Yangtze River Delta, China. Atmospheric Environment 42 (2008) 2023-2036
11. Greenwell L.L., Moreno T., Jones T.P., et al. Particle-induced oxidative damage is ameliorated by pulmonary antioxidants. Free Radical Biology & Medicine 32 (2002) 898-905
12. 10 particles: involvement of iron in generation of hydroxyl radical. Occupational and Environmental Medicine 53 (1996) 817-822
13. Katrinak K.A., Anderson J.R., and Buseck P.R. Individual particles types in the aerosol of Phoenix, Arizona. Environmental Science and Technology 29 (1995) 321-329
14. 10). Environmental Health Perspectives 105 S5 (1997) 1279-1283
15. 10. Journal of Environmental Sciences 18 1 (2006) 90-95
16. Lu S., Shao L., Jones T., Merolla L., and Richard R.J. Correlation between plasmid DNA damage induced by PM10 and trace metals in inhalable particulate matters in Beijing air. Science in China Series D: Earth Sciences 49 12 (2006) 1323-1331
17. 10. (in Chinese with English abstract). Acta Scientia Circumstanitae 25 7 (2005) 863-869
18. McNeilly J.D., Heal M., Beverland I., Howe A., Gibson M., Hibbs L., MacNee W., and Donaldson K. Soluble transition metals cause the pro-inflammatory effects of welding fumes in vitro. Toxicology and Applied Pharmacology 196 (2004) 95-107
19. Mill N.L., Tornqxist H., Gonzalez M.C., Vink E., Robinson S.D., Soderberg S., Boon N., Donaldson K., Sandstrom T., Blomberg A., and Newby D.E. Ischemic and thrombotic effect of dilute diesel-exhaust inhalation in men with coronary heart disease. The New England Journal of Medicine 357 11 (2007) 1075-1082
20. Moreno T., Merolla L., Gibbons W., Greenwell L., Jones T., and Richards R. Variations in the source, metal content and bioreactivity of technogenic aerosols: a case study from Port Talbot, Wales, UK. Science of the Total Environment 333 (2004) 59-73
21. Richards R.J., Atkins J., Marrs T.C., Brown R.F.R., and Masek L.C. The biochemical and pathological changes produced by the intratracheal instillation of certain components of zinc-hexachloroethane smoke. Toxicology 54 (1989) 79-88
22. Shi T., Schins R.P.F., Knaapen A.M., Kuhlbush T., Pitz M., Heinrich J., and Brom P.J.A. Hydroxy radical generation by electron paramagnetic resonance as a new method to monitor ambient particulate matter composition. Journal Environment and Monitoring 5 (2003) 550-556
23. Shi Z., Shao L., Jones T.P., Whittaker A., Senlin L., Berrube K., Taoe H., and Richards R. Characterization of airborne individual particles collected in an urban area, a satellite city and a clean air area in Beijing. Atmospheric Environment 37 (2003) 4097-4108
24. Shanghai Environmental Protection Bureau. 1994-2005 Shanghai Environmental Bulletin [R]. Available from: (2006).
25. Shao L., Shi Z., Jones T., Li J., Whittaker A., and BeruBe K. Bioreactivity of particulate matter in Beijing air: results from plasmid DNA assay. Science of the Total Environment 367 (2006) 261-272
26. 10 study in Beijing, China. Atmospheric Environment 41 (2007) 5316-5326
27. Tang X. Atmospheric Chemistry (1990), High Education Publisher, Beijing (in Chinese)
28. Utsunomiya S., Jensen K.A., Keeler G.J., and Ewing R.C. Direct identification of trace metals in fine and ultrafine particles in the Detroit urban atmosphere. Environmental Science and Technology 38 8 (2004) 2289-2297
29. Wätjen W., Haase H., Biagioli M., and Beyersmann D. Induction of apoptosis in mammalian cells by cadmium and zinc. Environmental Health Perspectives, Supplements 110 S5 (2002) 865-867
30. Wei F., and Chapman R.S. Study on Effect of Air Pollution on Respiratory Health Effect (2001), China Environmental Science Press, Beijing pp. 1-16 (in Chinese)
31. 2.5 and TSP aerosol in Shanghai. Atmospheric Environment 40 (2005) 2935-2952
32. 2.5 in Shanghai for a 1-year period. Atmospheric Environment 37 (2003) 499-510
33. Zhuang G., Guo J., Yuan H., and Zhang X. Coupling and feedback between iron and sulphur in air-sea exchange. Chinese Science Bulletin 48 4 (2003) 313-319 (in Chinese)