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Volumn 200, Issue 2, 2008, Pages 291-300

Mice overexpressing the 5-hydroxytryptamine transporter show no alterations in feeding behaviour and increased non-feeding responses to fenfluramine

Author keywords

5 HT; 5 HT transporter; Behavioural satiety sequence; Feeding; Fenfluramine; Transgenic mice

Indexed keywords

FENFLURAMINE; SEROTONIN RECEPTOR;

EID: 51249107534     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-008-1206-8     Document Type: Article
Times cited : (24)

References (44)
  • 2
    • 0031978809 scopus 로고    scopus 로고
    • Altered brain serotonin homeostasis and locomotor insensitivity to 3, 4-methylenedioxymethamphetamine ("Ecstasy") in serotonin transporter-deficient mice
    • D Bengel DL Murphy AM Andrews CH Wichems D Feltner A Heils R Mössner H Westphal KP Lesch 1998 Altered brain serotonin homeostasis and locomotor insensitivity to 3, 4-methylenedioxymethamphetamine ("Ecstasy") in serotonin transporter-deficient mice Mol Pharmacol 53 649 655
    • (1998) Mol Pharmacol , vol.53 , pp. 649-655
    • Bengel, D.1    Murphy, D.L.2    Andrews, A.M.3    Wichems, C.H.4    Feltner, D.5    Heils, A.6    Mössner, R.7    Westphal, H.8    Lesch, K.P.9
  • 3
    • 0028535338 scopus 로고
    • Molecular physiology of norepinephrine and serotonin transporters
    • R Blakely L De Felice H Hartzell 1994 Molecular physiology of norepinephrine and serotonin transporters J Exp Biol 196 263 281
    • (1994) J Exp Biol , vol.196 , pp. 263-281
    • Blakely, R.1    De Felice, L.2    Hartzell, H.3
  • 4
    • 0026604767 scopus 로고
    • Serotonin and the biology of feeding
    • JE Blundell 1992 Serotonin and the biology of feeding Am J Clin Nutr 55 155S 159S
    • (1992) Am J Clin Nutr , vol.55
    • Blundell, J.E.1
  • 5
    • 0022383490 scopus 로고
    • Behavioural structure and mechanisms of anorexia: Calibration of natural and abnormal inhibition of eating
    • JE Blundell PJ Rogers AJ Hill 1985 Behavioural structure and mechanisms of anorexia: calibration of natural and abnormal inhibition of eating Brain Res Bull 15 371 376
    • (1985) Brain Res Bull , vol.15 , pp. 371-376
    • Blundell, J.E.1    Rogers, P.J.2    Hill, A.J.3
  • 6
    • 33646853466 scopus 로고    scopus 로고
    • Reduced platelet [3H]paroxetine binding in anorexia nervosa: Relationship to eating symptoms and personality pathology
    • KR Bruce H Steiger NM Ng Ying Kin M Israel 2006 Reduced platelet [3H]paroxetine binding in anorexia nervosa: relationship to eating symptoms and personality pathology Psychiatry Res 142 225 232
    • (2006) Psychiatry Res , vol.142 , pp. 225-232
    • Bruce, K.R.1    Steiger, H.2    Ng Ying Kin, N.M.3    Israel, M.4
  • 8
    • 33646851374 scopus 로고    scopus 로고
    • Low density and high affinity of platelet [3H]paroxetine binding in women with bulimia nervosa
    • A Ekman C Sundblad-Elverfors M Landén T Eriksson E Eriksson 2006 Low density and high affinity of platelet [3H]paroxetine binding in women with bulimia nervosa Psychiatry Res 142 219 223
    • (2006) Psychiatry Res , vol.142 , pp. 219-223
    • Ekman, A.1    Sundblad-Elverfors, C.2    Landén, M.3    Eriksson, T.4    Eriksson, E.5
  • 9
    • 0024161982 scopus 로고
    • Mechanisms of effects of d-fenfluramine on brain serotonin metabolism in rats: Uptake inhibition versus release
    • RW Fuller HD Snoddy DW Robertson 1988 Mechanisms of effects of d-fenfluramine on brain serotonin metabolism in rats: uptake inhibition versus release Pharmacol Biochem Behav 30 715 721
    • (1988) Pharmacol Biochem Behav , vol.30 , pp. 715-721
    • Fuller, R.W.1    Snoddy, H.D.2    Robertson, D.W.3
  • 10
    • 0035138642 scopus 로고    scopus 로고
    • Association of a functional 5-HT transporter gene polymorphism with anorexia nervosa and food intake
    • F Fumeron D Betoulle R Aubert B Herbeth G Siest D Rigaud 2001 Association of a functional 5-HT transporter gene polymorphism with anorexia nervosa and food intake Mol Psychiatry 6 9 10
    • (2001) Mol Psychiatry , vol.6 , pp. 9-10
    • Fumeron, F.1    Betoulle, D.2    Aubert, R.3    Herbeth, B.4    Siest, G.5    Rigaud, D.6
  • 11
    • 0030218856 scopus 로고    scopus 로고
    • Metergoline antagonizes fluoxetine-induced suppression of food intake but not changes in the behavioural satiety sequence
    • JC Halford JE Blundell 1996 Metergoline antagonizes fluoxetine-induced suppression of food intake but not changes in the behavioural satiety sequence Pharmacol Biochem Behav 54 745 751
    • (1996) Pharmacol Biochem Behav , vol.54 , pp. 745-751
    • Halford, J.C.1    Blundell, J.E.2
  • 12
    • 33846246036 scopus 로고    scopus 로고
    • Serotonergic drugs: Effects on appetite expression and use for the treatment of obesity
    • JC Halford JA Harrold EJ Boyland CL Lawton JE Blundell 2007 Serotonergic drugs: effects on appetite expression and use for the treatment of obesity Drugs 67 27 55
    • (2007) Drugs , vol.67 , pp. 27-55
    • Halford, J.C.1    Harrold, J.A.2    Boyland, E.J.3    Lawton, C.L.4    Blundell, J.E.5
  • 15
    • 0036250544 scopus 로고    scopus 로고
    • Reduced aggression in mice lacking the serotonin transporter
    • A Holmes DL Murphy JN Crawley 2002 Reduced aggression in mice lacking the serotonin transporter Psychopharmacology 161 160 167
    • (2002) Psychopharmacology , vol.161 , pp. 160-167
    • Holmes, A.1    Murphy, D.L.2    Crawley, J.N.3
  • 16
    • 0038094446 scopus 로고    scopus 로고
    • Effects of systematic variation in presatiation and fasting on the behavioural satiety sequence in male rats
    • Y Ishii JE Blundell JC Halford RJ Rodgers 2003 Effects of systematic variation in presatiation and fasting on the behavioural satiety sequence in male rats Physiol Behav 79 227 238
    • (2003) Physiol Behav , vol.79 , pp. 227-238
    • Ishii, Y.1    Blundell, J.E.2    Halford, J.C.3    Rodgers, R.J.4
  • 19
    • 33847107065 scopus 로고    scopus 로고
    • The developing use of heterozygous mutant mouse models in brain monoamine transporter research
    • AV Kalueff RF Ren-Patterson DL Murphy 2007 The developing use of heterozygous mutant mouse models in brain monoamine transporter research Trends in Pharmacol Sci 28 122 127
    • (2007) Trends in Pharmacol Sci , vol.28 , pp. 122-127
    • Kalueff, A.V.1    Ren-Patterson, R.F.2    Murphy, D.L.3
  • 20
    • 0035312564 scopus 로고    scopus 로고
    • Double-blind placebo-controlled administration of fluoxetine in restricting- and restricting-purging-type anorexia nervosa
    • W Kaye T Nagata T Weltzin L Hsu M Sokol C McConaha K Plotnicov J Weise D Deep 2001 Double-blind placebo-controlled administration of fluoxetine in restricting- and restricting-purging-type anorexia nervosa Biol Psychiatry 49 644 652
    • (2001) Biol Psychiatry , vol.49 , pp. 644-652
    • Kaye, W.1    Nagata, T.2    Weltzin, T.3    Hsu, L.4    Sokol, M.5    McConaha, C.6    Plotnicov, K.7    Weise, J.8    Deep, D.9
  • 21
    • 18044364796 scopus 로고    scopus 로고
    • Neurobiology of anorexia nervosa: Clinical implications of alterations of the function of serotonin and other neuronal systems
    • WH Kaye GK Frank UF Bailer SE Henry 2005 Neurobiology of anorexia nervosa: clinical implications of alterations of the function of serotonin and other neuronal systems Int J Eat Disord 37 S15 S19
    • (2005) Int J Eat Disord , vol.37
    • Kaye, W.H.1    Frank, G.K.2    Bailer, U.F.3    Henry, S.E.4
  • 23
    • 0042343721 scopus 로고    scopus 로고
    • A human serotonin transporter mutation causes constitutive activation of transport activity
    • F Kilic DL Murphy G Rudnick 2003 A human serotonin transporter mutation causes constitutive activation of transport activity Mol Pharmacol 64 440 446
    • (2003) Mol Pharmacol , vol.64 , pp. 440-446
    • Kilic, F.1    Murphy, D.L.2    Rudnick, G.3
  • 24
    • 0029330841 scopus 로고
    • Serotoninergic manipulation, meal-induced satiety and eating pattern: Effect of fluoxetine in obese female subjects
    • CL Lawton JK Wales AJ Hill JE Blundell 1995 Serotoninergic manipulation, meal-induced satiety and eating pattern: effect of fluoxetine in obese female subjects Obes Res 3 345 356
    • (1995) Obes Res , vol.3 , pp. 345-356
    • Lawton, C.L.1    Wales, J.K.2    Hill, A.J.3    Blundell, J.E.4
  • 25
    • 8644255831 scopus 로고    scopus 로고
    • Reduced hypophagic effects of d-fenfluramine and the 5-HT2C receptor antagonist mCPP in 5-HT1B receptor knockout mice
    • MD Lee EM Somerville GA Kennett CT Dourish PG Clifton 2004 Reduced hypophagic effects of d-fenfluramine and the 5-HT2C receptor antagonist mCPP in 5-HT1B receptor knockout mice Psychopharmacology 176 39 49
    • (2004) Psychopharmacology , vol.176 , pp. 39-49
    • Lee, M.D.1    Somerville, E.M.2    Kennett, G.A.3    Dourish, C.T.4    Clifton, P.G.5
  • 29
    • 0025329192 scopus 로고
    • The effect of the 5-HT re-uptake inhibitor fluoxetine on food intake and body weight in healthy male subjects
    • J McGuirk T Silverstone 1990 The effect of the 5-HT re-uptake inhibitor fluoxetine on food intake and body weight in healthy male subjects Int J Obes 14 361 372
    • (1990) Int J Obes , vol.14 , pp. 361-372
    • McGuirk, J.1    Silverstone, T.2
  • 30
    • 0026555904 scopus 로고
    • Effects of the 5-HT uptake inhibitors, femoxetine and paroxetine, and a 5-HT1A/B agonist, eltoprazine, on the behavioural satiety sequence
    • J McGuirk R Muscat P Willner 1992 Effects of the 5-HT uptake inhibitors, femoxetine and paroxetine, and a 5-HT1A/B agonist, eltoprazine, on the behavioural satiety sequence Pharmacol Biochem Behav 41 801 805
    • (1992) Pharmacol Biochem Behav , vol.41 , pp. 801-805
    • McGuirk, J.1    Muscat, R.2    Willner, P.3
  • 32
    • 38649099407 scopus 로고    scopus 로고
    • Targeting the murine serotonin transporter: Insights into human neurobiology
    • DL Murphy K Lesch 2008 Targeting the murine serotonin transporter: insights into human neurobiology Nat Rev Neurosci 9 85 96
    • (2008) Nat Rev Neurosci , vol.9 , pp. 85-96
    • Murphy, D.L.1    Lesch, K.2
  • 35
    • 33749073279 scopus 로고    scopus 로고
    • Genetics of food intake and eating behavior phenotypes in humans
    • T Rankinen C Bouchard 2006 Genetics of food intake and eating behavior phenotypes in humans Annu Rev Nutr 26 413 434
    • (2006) Annu Rev Nutr , vol.26 , pp. 413-434
    • Rankinen, T.1    Bouchard, C.2
  • 38
    • 1642304002 scopus 로고    scopus 로고
    • Eating disorders and the serotonin connection: State, trait and developmental effects
    • H Steiger 2004 Eating disorders and the serotonin connection: state, trait and developmental effects J Psychiatry Neurosci 29 20 29
    • (2004) J Psychiatry Neurosci , vol.29 , pp. 20-29
    • Steiger, H.1
  • 41
    • 0029945345 scopus 로고    scopus 로고
    • Behavioural evidence that d-fenfluramine-induced anorexia in the rat is not mediated by the 5-HT1A receptor subtype
    • SP Vickers PG Clifton CT Dourish 1996 Behavioural evidence that d-fenfluramine-induced anorexia in the rat is not mediated by the 5-HT1A receptor subtype Psychopharmacology (Berl) 125 168 175
    • (1996) Psychopharmacology (Berl) , vol.125 , pp. 168-175
    • Vickers, S.P.1    Clifton, P.G.2    Dourish, C.T.3
  • 42
  • 44
    • 12344313055 scopus 로고    scopus 로고
    • Inhibition of the serotonin (5-hydroxytryptamine) tranporter reduces bone accrual during growth
    • SJ Warden AG Robling MS Sanders MM Bliziotes CH Turner 2005 Inhibition of the serotonin (5-hydroxytryptamine) tranporter reduces bone accrual during growth Endocrinology 146 685 693
    • (2005) Endocrinology , vol.146 , pp. 685-693
    • Warden, S.J.1    Robling, A.G.2    Sanders, M.S.3    Bliziotes, M.M.4    Turner, C.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.