Retrograde ejaculation occurs in the dog, but can be prevented by pre-treatment with phenylpropanolamine: A urodynamic study

Theriogenology

Volumn 70, Issue 7, 2008, Pages 1057-1064

  Beaufays, F ^a   Onclin, K ^b   Verstegen, J ^b  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

Dog; Dose titration study; Phenylpropanolamine; Retrograde ejaculation; Urodynamic

Indexed keywords

ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; PHENYLPROPANOLAMINE;

ANIMAL; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOG; DOSE RESPONSE; DRUG EFFECT; EJACULATION; MALE; PHYSIOLOGY; PROSTATE; SPERMATOZOON; URETHRA; URODYNAMICS;

ADRENERGIC ALPHA-AGONISTS; ANIMALS; CROSS-OVER STUDIES; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; EJACULATION; MALE; PHENYLPROPANOLAMINE; PROSTATE; SPERMATOZOA; URETHRA; URODYNAMICS;

ANIMALIA; CANIS FAMILIARIS;

EID: 51249103597     PISSN: 0093691X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.theriogenology.2008.06.026     Document Type: Article

References (54)

1. Collins J.P. Retrograde ejaculation. In: Bain J., Schill W.B., and Schwartzstein L. (Eds). Treatment of male infertility (1982), Springer Verlag, New York 179-189
2. Hershlag A., Schiff S.F., and DeCherney A.H. Retrograde ejaculation. Hum Reprod 6 (1991) 255-258
3. Yavetz H., Yogev L., Lessing J.B., Paz G., and Hommonnai Z.T. Retrograde ejaculation. Hum Reprod 9 (1994) 381-386
4. Dooley M.P., Pineda M.H., Hopper J.G., and Hsu W.H. Retrograde flow of spermatozoa into the urinary bladder of cats during electroejaculation, collection of semen with an artificial vagina, and mating. Am J Vet Res 52 (1991) 687-691
5. Axnér E., Ström B., Linde-Forsberg C., Gustavsson I., Lindbald K., and Wallgren M. Reproductive disorders in 10 domestic male cats. J Small Anim Pract 37 (1996) 394-401
6. Martin P.A., Pineda M.H., and Dooley M.P. Xylazine does not induce retrograde flow of spermatozoa into the urinary bladder of sexually rested boars. J Vet Med A Physiol Pathol Clin Med 50 (2003) 160-163
7. Brinsko S.P. Retrograde ejaculation in a stallion. J Am Vet Med Assoc 218 (2001) 551-553
8. Pineda M.H., and Dooley M.P. Effect of method of seminal collection on retrograde flow of spermatozoa into the urinary bladder of rams. Am J Vet Res 52 (1991) 307-313
9. Pineda M.H., Dooley M.P., Hembrough F.B., and Hsu W.H. Retrograde flow of spermatozoa into the urinary bladder of rams. Am J Vet Res 48 (1987) 562-568
10. Debruyne R. Retrograde ejaculation in bulls Vlaamse Diergeneeskunde. Tijdschrijft 56 (1987) 472-475
11. Dooley M.P., Pineda M.H., Naurer R.R., and Lunstra D.D. Evidence for retrograde flow of spermatozoa into the urinary bladder of bulls during electroejaculation. Theriogenology 26 (1986) 101-109
12. Schaffer N.E., Cranfield M., Fazleabas A.T., and Jeyendran R.S. Viable spermatozoa in the bladder after electroejaculation of lion-tailed macaques (Macaca silenus). J Reprod Fertil 86 (1989) 767-770
13. Schaffer N., Jeyendran R.S., and Beehler B. Improved sperm collection from the lowland gorilla: recovery of sperm from bladder and urethra following electroejaculation. Am J Primatol 24 (1991) 265-271
14. Dooley M.P., Pineda M.H., Hopper J.G., and Hsu W.H. Retrograde flow of spermatozoa into the urinary bladder of dogs during ejaculation or after sedation with xylazine. Am J Vet Res 51 (1990) 1574-1579
15. Kihara K., Sato K., Ando M., Sato T., and Oshima H. A mechanism of retrograde ejaculation after bilateral hypogastric nerve transactions in the dog. J Urol 148 (1992) 1307-1309
16. Post K., Barth A.D., Kiefer U.T., and Mapletoft R.J. Retrograde ejaculation in a Shetland sheepdoog. Can Vet J 33 (1992) 53-55
17. Root M.V., Johnston S.D., and Olson P.N. Concurrent retrograde ejaculation and hypothyroidism in a dog: case report. Theriogenology 41 (1994) 593-600
18. McMahon C., Abdo C., Incrocci M., et al. Disorders of orgasm and ejaculation in men. J Sex Med 1 (2004) 58-65
19. Davidson A.R. Reproductive physiology of the male in Cunningham. Textbook of veterinary physiology. 3rd ed. (2002), Saunders, Philadelphia p. 421-8, Chapter 29
20. Giulano F., and Clement P. Serotonine and premature ejaculation: from physiology to patient management. Eur Urol 50 (2006) 454-466
21. Lorenz M., and Kornegay J. Disorders of micturation. In: Lorenz M., and Kornegay J. (Eds). Handbook of veterinary neurology. 4th ed. (2004), Saunders, St Louis 75-90
22. Dewey C. Neurology and neuropharmacology of normal and abnormal urination. In: Deway C. (Ed). A practical guide to canine and feline neurology (2003), Oowa State Press ed., Ames 357-366
23. Barth V. Retrograde ejaculation as a cause of aspermia following retroperitoneal lymph node excision and the effective use of alpha-sympathomimetic drugs. Zum Urol Nephrol 83 (1990) 115-119
24. Swift S.E., and Ostegard D.R. Evaluation of current urodynamic testing methods in the diagnosis of genuine stress incontinence. Obstet Gynecol 86 (1995) 85-91
25. Hamaide A.J., Verstegen J., Snaps F.R., Onclin K., and Balligand M.H. Validation and comparison of the use of diuresis cystometry and retrograde filling cystometry at various infusion rates in female Beagle dogs. Am J Vet Res 64 (2003) 574-579
26. Kihara K., Sato K., Ando M., Sato T., and Oshima H. Lumbosacral sympathetic trunk as a compensatory pathway for seminal emission after bilateral hypogastric nerve transactions in the dog. J Urol 145 (1991) 640-643
27. Ye G., and Xiyu J. Action of autonomic drugs on the in vivo bladder base and proximal urethra in dogs. Chin Med J 110 (1997) 173-176
28. Gookin J.L., Stone E.A., and Sharp N.J. Urinary incontinence in dogs and cats Part I. Urethral pressure profilometry. Comp Cont Educ 18 (1996) 407-418
29. Augsburger H.R., Cruz-Orive L.M., and Arnold S. Morphology and stereology of female canine uretra correlated with urethral pressure profile. Acta Anat 148 (1993) 197-205
30. Andersson K.E. Pharmacology of lower urinary tract smooth muscles and penile erectile tissues. Pharmacol Rev 45 (1993) 253-308
31. Auguet M., Delaflotte S., and Chabrier P.E. Different alpha 1-adrenoreceptor subtypes mediate contraction in rabbit aorta and urethra. Eur J Pharmacol 287 (1995) 153-161
32. Modiri A.R., Frederickson M.G., Gillberg P.G., and Alberts P. Selectivity of oxymetazoline for urethral pressure vs blood pressure in the anaesthetized female rabbit. Scand J Nephrol 34 (2000) 151-156
33. Hashimoto S., Kigoshi S., and Muramatsu I. Neurogenic responses of urethra isolated from the dog. Eur J Pharmacol 213 (1992) 117-123
34. Mitchell C.A. Possible cardiovascular effect of phenylpropanolamine and belladonna alkaloids. Curr Ther Res Clin Exp 10 (1968) 47-53
35. Lasagna L. Phenylpropanolamine. A review (1988), John Wiley and Sons, New York p.1-440
36. Spence I., and Maddison J. The pharmacology of the autonomic nervous system. In: Maddison J., Page M., and Church D. (Eds). Small animal clinical pharmacology (2002), W.B. Saunders 53-68 Chapter 4
37. Tanagho E.A. Evolution of urodynamic studies. Urol Int 47 Suppl. 1 (1991) 5-8
38. Holt P.E., Gibbs C., and Wathes C.M. Simultaneous urethral pressure profilometry using a microtip transducer catheter in the bitch: effects of bitch position and transducer orientation. Neurourol Urodyn 9 (1990) 281-296
39. Holt P.E. Simultaneous urethral pressure profilometry in the bitch: methodology and reproducibility of the technique. Res Vet Sci 47 (1989) 110-116
40. Gillberg P.G., Fredrickson M.G., Ohman B.M., and Alberts P. The effect of phenylpropanolamine on the urethral pressure and heart rate is retained after repeated short-term administration in the unanaesthetized, conscious dog. Scand J Urol Nephrol 32 (1998) 171-176
41. Hensel P., Binder H., and Arnold S. Einfluss von Phenylpropanolamin und Ephedrin auf den urethralen Verschlussdruck und den arteriellen Blutdruck bei kastrierten Hundinnen. Kleintierpraxis 45 (2000) 617-628
42. CollsteL, and Lindskog M. Phenylpropanolamine in treatment of female stress urinary incontinence. Urology 30 (1987) 398-403
43. Richter K.P., and Ling G.V. Clinical response and urethral pressure profile changes after phenylpropanolamine in dogs with primary sphincter incompetence. J Am Vet Med Assoc 187 (1985) 605-611
44. Carofiglio F., Hamaide A., Farnir F., Balligand M., and Verstegen J.P. Evaluation of the urodynamic and hemodynamic effects of orally administered phenylpropanolamine and ephedrine in female dogs. Am J Vet Res 67 (2006) 723-730
45. Hamaide A.J., Verstegen J.P., Snaps F.R., Onclin K.J., and Balligand M.H. Influence of the estrous cycle on urodynamic and morphometric measurements of the lower portion of the urogenital tract in dogs. Am J Vet Res 66 (2005) 1075-1083
46. Linde-Forsberg C. Achieving canine pregnancy by using frozen or chilled extended semen. Vet Clin North Am Small Anim Pract 21 (1991) 467-485
47. Iguer-ouada M., and Verstegen J.P. Evaluation of the "Hamilton Thorn computer-based automated system" for dog semen analysis. Theriogenology 55 (2001) 733-749
48. Ochsenkühn R., Kamischke A., and Nieschlag E. Imipramine for successful treatment of retrograde ejaculation caused by retroperitoneal surgery. Int J Androl 22 (1999) 173-177
49. Silva P.D., Larson K.M.U., Van Every M.J., and Silva D.E. Successful treatment of retrograde ejaculation with sperm recovered from bladder washings. J Reprod Med 45 (2002) 957-960
50. Cleine J.H. Retrograde ejaculation: can sperm retrieval be simpler and noninvasive?. Fertil Steril 74 (2000) 416-417
51. Hotchkiss R.S., Pinto A.B., and Kleegman S. Artificial insemination with semen recovered from the bladder. Fertil Steril 6 (1955) 37-42
52. Stewart B.H., and Bergant J.A. Correction of retrograde ejaculation by sympathomimetic medication: preliminary report. Fertil Steril 25 (1974) 1073-1074
53. Brooks M.E., Berezin M., and Braf Z. Treatment of retrograde ejaculation with imipramine. Urology 15 (1980) 353-355
54. Thiagarajah S., Vaughan Jr. E.D., and Kitchin III J.D. Retrograde ejaculation: successful pregnancy following combined sympathomimetic medication and insemination. Fertil Steril 30 (1978) 96-97