Decreased ER-associated degradation of α-TCR induced by Grp78 depletion with the SubAB cytotoxin

International Journal of Biochemistry and Cell Biology

Volumn 40, Issue 12, 2008, Pages 2865-2879

  Lass, Agnieszka ^a   Kujawa, Marek ^b   McConnell, Elizabeth ^a   Paton, Adrienne W ^c   Paton, James C ^c   Wójcik, Cezary ^a  

^a Indiana University School of Medicine Evansville   (United States)

^b MEDICAL UNIVERSITY OF WARSAW   (Poland)

^c UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

Cytotoxin; endoplasmic reticulum (ER); ER associated degradation (ERAD); Subtilase; T cell receptor (TCR); Unfolded protein response (UPR)

Indexed keywords

AB5 SUBTILASE CYTOTOXIN; ACTIVATING TRANSCRIPTION FACTOR 3; ACTIVATING TRANSCRIPTION FACTOR 4; ACTIVATING TRANSCRIPTION FACTOR 6; ADENOSINE TRIPHOSPHATASE; CASPASE; CYTOTOXIN; FAT DROPLET; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; PROTEIN P97; STRESS ACTIVATED PROTEIN KINASE; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ELF 2 ALPHA; UNCLASSIFIED DRUG; VALOSIN CONTAINING PROTEIN; X BOX BINDING PROTEIN 1;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL STRESS; CELL STRUCTURE; CELL VACUOLE; CONTROLLED STUDY; CYTOPLASM; EMBRYO; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HELA CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; INCUBATION TIME; LIPID STORAGE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN SYNTHESIS; PROTEIN SYNTHESIS INHIBITION; RNA SPLICING; UPREGULATION;

ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; ENDOPLASMIC RETICULUM; ESCHERICHIA COLI PROTEINS; HEAT-SHOCK PROTEINS; HELA CELLS; HUMANS; MOLECULAR CHAPERONES; PROTEIN BIOSYNTHESIS; RECEPTORS, ANTIGEN, T-CELL; RNA INTERFERENCE; SUBTILISINS;

EID: 51249096553     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2008.06.003     Document Type: Article

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