Keratinocyte growth factor protects against Clara cell injury induced by naphthalene

European Respiratory Journal

Volumn 32, Issue 3, 2008, Pages 694-704

  Yildirim, A O ^a   Veith, M ^a   Rausch, T ^a   Muller B ^a   Kilb, P ^a   Van Winkle, L S ^b   Fehrenbach, H ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Airway epithelial injury; Cytochrome P450; Keratinocyte growth factor; Naphthalene; Secretoglobin

Indexed keywords

CLARA CELL PROTEIN; CYCLINE; CYTOCHROME P450 2A; CYTOCHROME P450 2F2; ETHIDIUM; MESSENGER RNA; NAPHTHALENE; PALIFERMIN; SODIUM; TOXIN; UNCLASSIFIED DRUG; CYP2F2 PROTEIN, MOUSE; CYTOCHROME P450; KERATINOCYTE GROWTH FACTOR; NAPHTHALENE DERIVATIVE; RECOMBINANT PROTEIN;

ACUTE DISEASE; AIRFLOW; AIRWAY OBSTRUCTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY PLETHYSMOGRAPHY; CELL COUNT; CELL DAMAGE; CELL DEATH; CELL LOSS; CELL MEMBRANE PERMEABILITY; CELL PROLIFERATION; CLARA CELL; CONTROLLED STUDY; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; LUNG FUNCTION; MALE; MICRODISSECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ACUTE LUNG INJURY; ANIMAL; BRONCHIOLE; CHEMICALLY INDUCED DISORDER; CYTOLOGY; DISEASE MODEL; DRUG EFFECT; EPITHELIUM CELL; METABOLISM;

ACUTE LUNG INJURY; ANIMALS; BRONCHIOLES; CYTOCHROME P-450 ENZYME SYSTEM; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; FIBROBLAST GROWTH FACTOR 7; MICE; NAPHTHALENES; PLETHYSMOGRAPHY, WHOLE BODY; RECOMBINANT PROTEINS;

EID: 51049113656     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00155107     Document Type: Article

References (50)

1. Puchelle E, Zahm JM, Tournier JM, Coraux C. Airway epithelial repair, regeneration, and remodeling after injury in chronic obstructive pulmonary disease. Proc Am Thorac Soc 2006; 3: 726-733.
2. Gauderman WJ, Avol E, Gilliland F, et al. The effect of air pollution on lung development from 10 to 18 years of age. N Engl J Med 2004; 351: 1057-1067.
3. Leikauf GD. Hazardous air pollutants and asthma. Environ Health Perspect 2002; 110: 505-526.
4. Plopper CG, Hyde DM. Epithelial cells of bronchioles. In: Parent RA., ed. Comparative Biology of the Normal Lung. Boca Raton, CRC Press, 1992; pp. 85-92.
5. Plopper CG, Van Winkle LS, Fanucchi MV, et al. Early events in naphthalene-induced acute Clara cell toxicity. II. Comparison of glutathione depletion and histopathology by airway location. Am J Respir Cell Mol Biol 2001; 24: 272-281.
6. Preuss R, Angerer J, Drexler H. Naphthalene - an environmental and occupational toxicant. Int Arch Occup Environ Health 2003; 76: 556-576.
7. Preuss R, Drexler H, Bottcher M, Wilhelm M, Bruning T, Angerer J. Current external and internal exposure to naphthalene of workers occupationally exposed to polycyclic aromatic hydrocarbons in different industries. Int Arch Occup Environ Health 2005; 78: 355-362.
8. Witschi H, Espiritu I, Maronpot RR, Pinkerton KE, Jones AD. The carcinogenic potential of the gas phase of environmental tobacco smoke. Carcinogenesis 1997; 18: 2035-2042.
9. Van Winkle LS, Buckpitt AR, Nishio SJ, Isaac JM, Plopper CG. Cellular response in naphthalene-induced Clara cell injury and bronchiolar epithelial repair in mice. Am J Physiol 1995; 269: 800-818.
10. Massaro GD, Singh G, Mason R, Plopper CG, Malkinson AM, Gail DB. Biology of the Clara cell. Am J Physiol 1994; 266: L101-L106.
11. Fanucchi MV, Murphy ME, Buckpitt AR, Philpot RM, Plopper CG. Pulmonary cytochrome P450 monooxygenase and Clara cell differentiation in mice. Am J Respir Cell Mol Biol 1997; 17: 302-314.
12. Shultz MA, Choudary PV, Buckpitt AR. Role of murine cytochrome P-450 2F2 in metabolic activation of naphthalene and metabolism of other xenobiotics. J Pharmacol Exp Ther 1999; 290: 281-288.
13. Plopper CG, Macklin J, Nishio SJ, Hyde DM, Buckpitt AR. Relationship of cytochrome P-450 activity to Clara cell cytotoxicity. III. Morphometric comparison of changes in the epithelial populations of terminal bronchioles and lobar bronchi in mice, hamsters, and rats after parenteral administration of naphthalene. Lab Invest 1992; 67: 553-565.
14. Ware LB, Matthay MA. Keratinocyte and hepatocyte growth factors in the lung: roles in lung development, inflammation, and repair. Am J Physiol Lung Cell Mol Physiol 2002; 282: 924-940.
15. Finch PW, Cunha GR, Rubin JS, Wong J, Ron D. Pattern of keratinocyte growth factor and keratinocyte growth factor receptor expression during mouse fetal development suggests a role in mediating morphogenetic mesenchymal-epithelial interactions. Dev Dyn 1995; 203: 223-240.
16. Boardman KC, Aryal AM, Miller WM, Waters CM. Actin re-distribution in response to hydrogen peroxide in airway epithelial cells. J Cell Physiol 2004; 199: 57-66.
17. Fehrenbach H, Fehrenbach A, Pan T, Kasper M, Mason RJ. Keratinocyte growth factor-induced proliferation of rat airway epithelium is restricted to Clara cells in vivo. Eur Respir J 2002; 20: 1185-1197.
18. Savla U, Waters CM. Barrier function of airway epithelium: effects of radiation and protection by keratinocyte growth factor. Radiat Res 1998; 150: 195-203.
19. Chapman KE, Waters CM, Miller WM. Continuous exposure of airway epithelial cells to hydrogen peroxide: protection by KGF. J Cell Physiol 2002; 192: 71-80.
20. Tillie-Leblond I, Gosset P, Le Berre R, et al. Keratinocyte growth factor improves alterations of lung permeability and bronchial epithelium in allergic rats. Eur Respir J 2007; 30: 31-39.
21. Waters CM, Savla U. Keratinocyte growth factor accelerates wound closure in airway epithelium during cyclic mechanical strain. J Cell Physiol 1999; 181: 424-432.
22. Gomperts BN, Belperio JA, Fishbein MC, Keane MP, Burdick MD, Strieter RM. Keratinocyte growth factor improves repair in the injured tracheal epithelium. Am J Respir Cell Mol Biol 2007; 37: 48-56.
23. Prince LS, Karp PH, Moninger TO, Welsh MJ. KGF alters gene expression in human airway epithelia: potential regulation of the inflammatory response. Physiol Genomics 2001; 6: 81-89.
24. Ding X, Kaminsky LS. Human extrahepatic cytochromes P450: function in xenobiotic metabolism and tissue-selective chemical toxicity in the respiratory and gastrointestinal tracts. Annu Rev Pharmacol Toxicol 2003; 43: 149-173.
25. Hsu E, Osslund T, Nybo R, et al. Enhanced stability of recombinant keratinocyte growth factor by mutagenesis. Protein Eng Des Sel 2006; 19: 147-153.
26. Van Winkle LS, Buckpitt AR, Plopper CG. Maintenance of differentiated murine Clara cells in microdissected airway cultures. Am J Respir Cell Mol Biol 1996; 14: 586-598.
27. Hoymann HG. Invasive and noninvasive lung function measurements in rodents. J Pharmacol Toxicol Methods 2007; 55: 16-26.
28. Ulrich K, Stern M, Goddard ME, et al. Keratinocyte growth factor therapy in murine oleic acid-induced acute lung injury. Am J Physiol Lung Cell Mol Physiol 2005; 288: L1179-L1192.
29. Van Winkle LS, Gunderson AD, Shimizu JA, Baker GL, Brown CD. Gender differences in naphthalene metabolism and naphthalene-induced acute lung injury. Am J Physiol Lung Cell Mol Physiol 2002; 282: L1122-L1134.
30. Hyde DM, Harkema JR, Tyler NK, Plopper CG. Design-based sampling and quantitation of the respiratory airways. Toxicol Pathol 2006; 34: 286-295.
31. Elizur A, Adair-Kirk TL, Kelley DG, Griffin GL, deMello DE, Senior RM. TNF-α from macrophages enhances LPS-induced Clara cell expression of keratinocyte-derived chemokine. Am J Respir Cell Mol Biol 2008; 38: 8-15.
32. 2-induced airway inflammation is associated with progressive airflow limitation and development of emphysemalike lesions in C57BL/6 mice. Exp Toxicol Pathol 2005; 56: 341-350.
33. Klug J, Beier HM, Bernard A, et al. Uteroglobin/Clara cell 10-kDa family of proteins: nomenclature committee report. Ann NY Acad Sci 2000; 923: 348-354.
34. Yano T, Mason RJ, Pan T, Deterding RR, Nielsen LD, Shannon JM. KGF regulates pulmonary epithelial proliferation and surfactant protein gene expression in adult rat lung. Am J Physiol Lung Cell Mol Physiol 2000; 279: L1146-L1158.
35. Plopper CG, Suverkropp C, Morin D, Nishio S, Buckpitt A. Relationship of cytochrome P-450 activity to Clara cell cytotoxicity. I. Histopathologic comparison of the respiratory tract of mice, rats and hamsters after parenteral administration of naphthalene. J Pharmacol Exp Ther 1992; 261: 353-363.
36. Van Winkle LS, Isaac JM, Plopper CG. Repair of naphthalene-injured microdissected airways in vitro. Am J Respir Cell Mol Biol 1996; 15: 1-8.
37. Stripp BR, Maxson K, Mera R, Singh G. Plasticity of airway cell proliferation and gene expression after acute naphthalene injury. Am J Physiol 1995; 269: L791-L799.
38. Reynolds SD, Giangreco A, Power JH, Stripp BR. Neuroepithelial bodies of pulmonary airways serve as a reservoir of progenitor cells capable of epithelial regeneration. Am J Pathol 2000; 156: 269-278.
39. Giangreco A, Reynolds SD, Stripp BR. Terminal bronchioles harbor a unique airway stem cell population that localizes to the bronchoalveolar duct junction. Am J Pathol 2002; 161: 173-182.
40. Park KS, Wells JM, Zorn AM, et al. Transdifferentiation of ciliated cells during repair of the respiratory epithelium. Am J Respir Cell Mol Biol 2006; 34: 151-157.
41. Lawson GW, Van Winkle LS, Toskala E, Senior RM, Parks WC, Plopper CG. Mouse strain modulates the role of the ciliated cell in acute tracheobronchial airway injurydistal airways. Am J Pathol 2002; 160: 315-327.
42. Rawlins EL, Ostrowski LE, Randell SH, Hogan BL. Lung development and repair: contribution of the ciliated lineage. Proc Natl Acad Sci USA 2007; 104: 410-417.
43. Postlethwait EM, Joad JP, Hyde DM, et al. Three-dimensional mapping of ozone-induced acute cytotoxicity in tracheobronchial airways of isolated perfused rat lung. Am J Respir Cell Mol Biol 2000; 22: 191-199.
44. Vijayaraghavan R, Schaper M, Thompson R, et al. Computer assisted recognition and quantitation of the effects of airborne chemicals acting at different areas of the respiratory tract in mice. Arch Toxicol 1994; 68: 490-499.
45. Glaab T, Hoymann HG, Hohlfeld JM, et al. Noninvasive measurement of midexpiratory flow indicates bronchoconstriction in allergic rats. J Appl Physiol 2002; 93: 1208-1214.
46. Glaab T, Ziegert M, Baelder R, et al. Invasive versus noninvasive measurement of allergic and cholinergic airway responsiveness in mice. Respir Res 2005; 6: 139.
47. Hohlfeld JM, Hoymann HG, Tschernig T, Fehrenbach A, Krug N, Fehrenbach H. Keratinocyte growth factor transiently alters pulmonary function in rats. J Appl Physiol 2004; 96: 704-710.
48. Atkinson JJ, Toennies HM, Holmbeck K, Senior RM. Membrane type 1 matrix metalloproteinase is necessary for distal airway epithelial repair and keratinocyte growth factor receptor expression after acute injury. Am J Physiol Lung Cell Mol Physiol 2007; 293: L600-L610.
49. Singh G, Katyal SL. Clara cells and Clara cell 10 kD protein (CC10). Am J Respir Cell Mol Biol 1997; 17: 141-143.
50. Reynolds SD, Hong KU, Giangreco A, et al. Conditional Clara cell ablation reveals a self-renewing progenitor function of pulmonary neuroendocrine cells. Am J Physiol Lung Cell Mol Physiol 2000; 278: 1256-1263.