-
1
-
-
0032787927
-
The connective tissue growth factor/cysteine rich/ nephroblastoma overexpressed (CCN) family
-
Brigstock DR: The connective tissue growth factor/cysteine rich/ nephroblastoma overexpressed (CCN) family. Endocr Rev 20: 189-206, 1999.
-
(1999)
Endocr Rev
, vol.20
, pp. 189-206
-
-
Brigstock, D.R.1
-
2
-
-
0034455322
-
CCN proteins are distinct from and should not be considered members of the insulin-like growth factor-binding protein superfamily
-
Grotendorst GR, Lau LF and Perbal B: CCN proteins are distinct from and should not be considered members of the insulin-like growth factor-binding protein superfamily. Endocrinology 141: 2254-2256, 2000.
-
(2000)
Endocrinology
, vol.141
, pp. 2254-2256
-
-
Grotendorst, G.R.1
Lau, L.F.2
Perbal, B.3
-
3
-
-
0032568608
-
CYR61, a product of a growth factor-inducible immediate early gene, promotes angiogenesis and tumor growth
-
Babic AM, Kireeva ML, Kolesnikova TV and Lau LF: CYR61, a product of a growth factor-inducible immediate early gene, promotes angiogenesis and tumor growth. Proc Natl Acad Sci USA 95: 6355-6360, 1998.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6355-6360
-
-
Babic, A.M.1
Kireeva, M.L.2
Kolesnikova, T.V.3
Lau, L.F.4
-
4
-
-
0029965446
-
Cyr61, a product of a growth factor-inducible immediate-early gene, promotes cell proliferation, migration and adhesion
-
Kireeva ML, Mo FE, Yang GP and Lau LF: Cyr61, a product of a growth factor-inducible immediate-early gene, promotes cell proliferation, migration and adhesion. Mol Cell Biol 16: 1326-1334, 1996.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 1326-1334
-
-
Kireeva, M.L.1
Mo, F.E.2
Yang, G.P.3
Lau, L.F.4
-
5
-
-
59649097998
-
The role of CCN1 in tumorigenesis and cancer progression
-
Perbal B ed, Imperial College Press
-
O'Kelly J and Koeffler HP: The role of CCN1 in tumorigenesis and cancer progression. In: CCN proteins. Perbal B (ed). Imperial College Press, 2005.
-
(2005)
CCN proteins
-
-
O'Kelly, J.1
Koeffler, H.P.2
-
6
-
-
0035957912
-
Breast cancer: Cyr61 is overexpressed, estrogen inducible and associated with more advanced disease
-
Xie D, Miller CW, O'Kelly J, et al: Breast cancer: Cyr61 is overexpressed, estrogen inducible and associated with more advanced disease. J Biol Chem 276: 14187-14194, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 14187-14194
-
-
Xie, D.1
Miller, C.W.2
O'Kelly, J.3
-
7
-
-
0035861726
-
Cyr61, a member of CCN family, is a tumor suppressor in non-small cell lung cancer
-
Tong X, Xie D, O'Kelly J, Miller CW, Muller-Tidow C and Koeffler HP: Cyr61, a member of CCN family, is a tumor suppressor in non-small cell lung cancer. J Biol Chem 276: 47709-47714, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 47709-47714
-
-
Tong, X.1
Xie, D.2
O'Kelly, J.3
Miller, C.W.4
Muller-Tidow, C.5
Koeffler, H.P.6
-
8
-
-
0347915577
-
CCN proteins: Multifunctional signalling regulators
-
Perbal B: CCN proteins: multifunctional signalling regulators. Lancet 363: 62-64, 2004.
-
(2004)
Lancet
, vol.363
, pp. 62-64
-
-
Perbal, B.1
-
9
-
-
27544463752
-
Proteolysis of CCN1 by plasmin: Functional implications
-
Pendurthi UR, Tran TT, Post M and Rao LV: Proteolysis of CCN1 by plasmin: functional implications. Cancer Res 65: 9705-9711, 2005.
-
(2005)
Cancer Res
, vol.65
, pp. 9705-9711
-
-
Pendurthi, U.R.1
Tran, T.T.2
Post, M.3
Rao, L.V.4
-
10
-
-
0027219381
-
The modular architecture of a new family of growth regulators related to connective tissue growth factor
-
Bork P: The modular architecture of a new family of growth regulators related to connective tissue growth factor. FEBS Lett 327: 125-130, 1993.
-
(1993)
FEBS Lett
, vol.327
, pp. 125-130
-
-
Bork, P.1
-
11
-
-
6344220061
-
Identification of a novel integrin alphavbeta3 binding site in CCN1 (CYR61) critical for pro-angiogenic activities in vascular endothelial cells
-
Chen N, Leu SJ, Todorovic V, Lam SC and Lau LF: Identification of a novel integrin alphavbeta3 binding site in CCN1 (CYR61) critical for pro-angiogenic activities in vascular endothelial cells. J Biol Chem 279: 44166-44176, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 44166-44176
-
-
Chen, N.1
Leu, S.J.2
Todorovic, V.3
Lam, S.C.4
Lau, L.F.5
-
12
-
-
6344260672
-
Targeted mutagenesis of the angiogenic protein CCN1 (CYR61). Selective inactivation of integrin alpha6beta1-heparan sulfate proteoglycan coreceptor-mediated cellular functions
-
Leu SJ, Chen N, Chen CC, et al: Targeted mutagenesis of the angiogenic protein CCN1 (CYR61). Selective inactivation of integrin alpha6beta1-heparan sulfate proteoglycan coreceptor-mediated cellular functions. J Biol Chem 279: 44177-44187, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 44177-44187
-
-
Leu, S.J.1
Chen, N.2
Chen, C.C.3
-
13
-
-
0037493314
-
Identification of a novel integrin αMβ2 Binding Site in CCN1(CYR61), a matr-cellular protein expressed in healing wounds and atherosclerotic lesions
-
Schober JM, Lau LF, Ugarova TP and Lam SC: Identification of a novel integrin αMβ2 Binding Site in CCN1(CYR61), a matr-cellular protein expressed in healing wounds and atherosclerotic lesions. J Biol Chem 278: 25808-25815, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 25808-25815
-
-
Schober, J.M.1
Lau, L.F.2
Ugarova, T.P.3
Lam, S.C.4
-
14
-
-
0034637596
-
Adhesion of human skin fibroblasts to Cyr61 is mediated through integrin α6β1 and cell surface heparan sulfate proteoglycans
-
Chen N, Chen CC and Lau LF: Adhesion of human skin fibroblasts to Cyr61 is mediated through integrin α6β1 and cell surface heparan sulfate proteoglycans. J Biol Chem 275: 24953-24961, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 24953-24961
-
-
Chen, N.1
Chen, C.C.2
Lau, L.F.3
-
15
-
-
4344560651
-
Integrins in mammary gland development and differentiation of mammary epithelium
-
Taddei I, Faraldo MM, Teuliere J, Deugnier MA, Thiery JP and Glukhova MA: Integrins in mammary gland development and differentiation of mammary epithelium. J Mammary Gland Biol Neoplasia 8: 383-394, 2003.
-
(2003)
J Mammary Gland Biol Neoplasia
, vol.8
, pp. 383-394
-
-
Taddei, I.1
Faraldo, M.M.2
Teuliere, J.3
Deugnier, M.A.4
Thiery, J.P.5
Glukhova, M.A.6
-
17
-
-
0035969233
-
Integrin-linked linase and its interactors: A new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexes
-
Wu C and Dedhar S: Integrin-linked linase and its interactors: a new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexes. J Cell Biol 155: 505-510, 2001.
-
(2001)
J Cell Biol
, vol.155
, pp. 505-510
-
-
Wu, C.1
Dedhar, S.2
-
18
-
-
19844379736
-
AlphaVbeta3 integrin regulates heregulin (HRG)-induced cell proliferation and survival in breast cancer
-
Vellon L, Menendez JA and Lupu R: AlphaVbeta3 integrin regulates heregulin (HRG)-induced cell proliferation and survival in breast cancer. Oncogene 24: 3759-3773, 2005.
-
(2005)
Oncogene
, vol.24
, pp. 3759-3773
-
-
Vellon, L.1
Menendez, J.A.2
Lupu, R.3
-
19
-
-
13444291204
-
A novel CYR61-triggered 'CYR61-alphavbeta3 integrin loop' regulates breast cancer cell survival and chemosensitivity through activation of ERK1/ ERK2 MAPK signaling pathway
-
Menendez JA, Vellon L, Mehmi I, Teng PK, Griggs DW and Lupu R: A novel CYR61-triggered 'CYR61-alphavbeta3 integrin loop' regulates breast cancer cell survival and chemosensitivity through activation of ERK1/ ERK2 MAPK signaling pathway. Oncogene 24: 761-779, 2005.
-
(2005)
Oncogene
, vol.24
, pp. 761-779
-
-
Menendez, J.A.1
Vellon, L.2
Mehmi, I.3
Teng, P.K.4
Griggs, D.W.5
Lupu, R.6
-
20
-
-
0034667466
-
Expression and function of CYR61, an angiogenic factor, in breast cancer cell lines and tumor biopsies
-
Tsai MS, Hornby AE, Lakins J and Lupu R: Expression and function of CYR61, an angiogenic factor, in breast cancer cell lines and tumor biopsies. Cancer Res 60: 5603-5607, 2000.
-
(2000)
Cancer Res
, vol.60
, pp. 5603-5607
-
-
Tsai, M.S.1
Hornby, A.E.2
Lakins, J.3
Lupu, R.4
-
21
-
-
0035020071
-
Cyr61, a member of the CCN family, is required for MCF-7 cell proliferation: Regulation by 17beta-estradiol and overexpression in human breast cancer
-
Sampath D, Winneker RC and Zhang Z: Cyr61, a member of the CCN family, is required for MCF-7 cell proliferation: regulation by 17beta-estradiol and overexpression in human breast cancer. Endocrinology 142: 2540-2548, 2001.
-
(2001)
Endocrinology
, vol.142
, pp. 2540-2548
-
-
Sampath, D.1
Winneker, R.C.2
Zhang, Z.3
-
22
-
-
0035893738
-
Elevated levels of connective tissue growth factor, WISP-1 and CYR61 in primary breast cancers associated with more advanced features
-
Xie D, Nakachi K, Wang H, Elashoff R and Koeffler HP: Elevated levels of connective tissue growth factor, WISP-1 and CYR61 in primary breast cancers associated with more advanced features. Cancer Res 61: 8917-8923, 2001.
-
(2001)
Cancer Res
, vol.61
, pp. 8917-8923
-
-
Xie, D.1
Nakachi, K.2
Wang, H.3
Elashoff, R.4
Koeffler, H.P.5
-
23
-
-
0037153439
-
Cyr61 promotes breast tumorigenesis and cancer progression
-
Tsai MS, Bogart DF, Castaneda JM, Li P and Lupu R: Cyr61 promotes breast tumorigenesis and cancer progression. Oncogene 21: 8178-8185, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 8178-8185
-
-
Tsai, M.S.1
Bogart, D.F.2
Castaneda, J.M.3
Li, P.4
Lupu, R.5
-
24
-
-
0035030707
-
Aberrant expression of Cyr61, a member of the CCN (CTGF/Cyr61/Cef10/NOVH) family, and dysregulation by 17 beta-estradiol and basic fibroblast growth factor in human uterine leiomyomas
-
Sampath D, Zhu Y, Winneker RC and Zhang Z: Aberrant expression of Cyr61, a member of the CCN (CTGF/Cyr61/Cef10/NOVH) family, and dysregulation by 17 beta-estradiol and basic fibroblast growth factor in human uterine leiomyomas. J Clin Endocrinol Metab 86: 1707-1715, 2001.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 1707-1715
-
-
Sampath, D.1
Zhu, Y.2
Winneker, R.C.3
Zhang, Z.4
-
25
-
-
11244333091
-
Differential expression of the CCN family members Cyr61, CTGF and Nov in human breast cancer
-
Jiang WG, Watkins G, Fodstad O, Douglas-Jones A, Mokbel K and Mansel RE: Differential expression of the CCN family members Cyr61, CTGF and Nov in human breast cancer. Endocr Relat Cancer 11: 781-791, 2004.
-
(2004)
Endocr Relat Cancer
, vol.11
, pp. 781-791
-
-
Jiang, W.G.1
Watkins, G.2
Fodstad, O.3
Douglas-Jones, A.4
Mokbel, K.5
Mansel, R.E.6
-
26
-
-
18144380288
-
Individual domains of connective tissue growth factor regulate fibroblast proliferation and myofibroblast differentiation
-
Grotendorst GR and Duncan MR: Individual domains of connective tissue growth factor regulate fibroblast proliferation and myofibroblast differentiation. FASEB J 19: 729-738, 2005.
-
(2005)
FASEB J
, vol.19
, pp. 729-738
-
-
Grotendorst, G.R.1
Duncan, M.R.2
-
27
-
-
33748077425
-
Nuclear addressing provides a clue for the transforming activity of amino-truncated CCN3 proteins
-
Planque N, Long Li C, Saule S, Bleau AM and Perbal B: Nuclear addressing provides a clue for the transforming activity of amino-truncated CCN3 proteins. J Cell Biochem 99: 105-116, 2006.
-
(2006)
J Cell Biochem
, vol.99
, pp. 105-116
-
-
Planque, N.1
Long Li, C.2
Saule, S.3
Bleau, A.M.4
Perbal, B.5
-
28
-
-
0033541389
-
The CCN family of angiogenic regulators: The integrin connection
-
Lau LF and Lam SC-T: The CCN family of angiogenic regulators: The integrin connection. Exp Cell Res 248: 44-57, 1999.
-
(1999)
Exp Cell Res
, vol.248
, pp. 44-57
-
-
Lau, L.F.1
Lam, S.C.-T.2
-
29
-
-
0035999132
-
The dominance of the micro-environment in breast and ovarian cancer
-
Roskelley CD and Bissell MJ: The dominance of the micro-environment in breast and ovarian cancer. Semin Cancer Biol 12: 97-110, 2002.
-
(2002)
Semin Cancer Biol
, vol.12
, pp. 97-110
-
-
Roskelley, C.D.1
Bissell, M.J.2
-
30
-
-
33751252276
-
Cancer metastasis: Building a framework
-
Gupta GP and Massague J: Cancer metastasis: building a framework. Cell 127: 679-695, 2006.
-
(2006)
Cell
, vol.127
, pp. 679-695
-
-
Gupta, G.P.1
Massague, J.2
-
31
-
-
0035861590
-
The angiogenic factor Cyr61 activates a genetic program for wound healing in human skin fibroblasts
-
Chen CC, Mo FE and Lau LF: The angiogenic factor Cyr61 activates a genetic program for wound healing in human skin fibroblasts. J Biol Chem 276: 47329-47337, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 47329-47337
-
-
Chen, C.C.1
Mo, F.E.2
Lau, L.F.3
-
32
-
-
0033588380
-
Activation-dependent adhesion of human platelets to Cyr61 and Fisp12/ mouse connective tissue growth factor is mediated through integrin alpha(IIb)beta(3)
-
Jedsadayanmata A, Chen CC, Kireeva ML, Lau LF and Lam SC: Activation-dependent adhesion of human platelets to Cyr61 and Fisp12/ mouse connective tissue growth factor is mediated through integrin alpha(IIb)beta(3). J Biol Chem 274: 24321-24327, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 24321-24327
-
-
Jedsadayanmata, A.1
Chen, C.C.2
Kireeva, M.L.3
Lau, L.F.4
Lam, S.C.5
-
33
-
-
0035877765
-
CYR61 stimulates human skin fibroblast migration through Integrin alpha v beta 5 and enhances mitogenesis through integrin alpha v beta 3, independent of its carboxyl-terminal domain
-
Grzeszkiewicz TM, Kirschling DJ, Chen N and Lau LF: CYR61 stimulates human skin fibroblast migration through Integrin alpha v beta 5 and enhances mitogenesis through integrin alpha v beta 3, independent of its carboxyl-terminal domain. J Biol Chem 276: 21943-21950, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 21943-21950
-
-
Grzeszkiewicz, T.M.1
Kirschling, D.J.2
Chen, N.3
Lau, L.F.4
-
34
-
-
0029937529
-
Integrin alpha V beta 3 expression by bone-residing breast cancer metastases
-
Liapis H, Flath A and Kitazawa S: Integrin alpha V beta 3 expression by bone-residing breast cancer metastases. Diagn Mol Pathol 5: 127-135, 1996.
-
(1996)
Diagn Mol Pathol
, vol.5
, pp. 127-135
-
-
Liapis, H.1
Flath, A.2
Kitazawa, S.3
-
35
-
-
0036676419
-
Integrin alpha(v) beta3 expression confers on tumor cells a greater propensity to metastasize to. bone
-
Pecheur I, Peyruchaud O, Serre CM, et al: Integrin alpha(v) beta3 expression confers on tumor cells a greater propensity to metastasize to. bone. FASEB J 16: 1266-1238, 2002.
-
(2002)
FASEB J
, vol.16
, pp. 1266-1238
-
-
Pecheur, I.1
Peyruchaud, O.2
Serre, C.M.3
-
36
-
-
0035950544
-
-
White DE, Cardiff RD, Dedhar S and Muller WJ: Mammary epithelial-specific expression of the integrin-linked kinase (ILK) results in the induction of mammary gland hyperplasias and tumors in transgenic mice. Oncogene 20: 7064-7072, 2001.
-
White DE, Cardiff RD, Dedhar S and Muller WJ: Mammary epithelial-specific expression of the integrin-linked kinase (ILK) results in the induction of mammary gland hyperplasias and tumors in transgenic mice. Oncogene 20: 7064-7072, 2001.
-
-
-
-
37
-
-
0242580792
-
Mechanisms of hypoxic gene regulation of angiogenesis factor Cyr61 in melanoma cells
-
Kunz M, Moeller S, Koczan D, et al: Mechanisms of hypoxic gene regulation of angiogenesis factor Cyr61 in melanoma cells. J Biol Chem 278: 45651-45660, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 45651-45660
-
-
Kunz, M.1
Moeller, S.2
Koczan, D.3
-
38
-
-
33845794955
-
The human Cyr61 gene is a transcriptional target of transforming growth factor beta in cancer cells
-
Bartholin L, Wessner LL, Chirgwin JM and Guise TA: The human Cyr61 gene is a transcriptional target of transforming growth factor beta in cancer cells. Cancer Lett 246: 230-236, 2007.
-
(2007)
Cancer Lett
, vol.246
, pp. 230-236
-
-
Bartholin, L.1
Wessner, L.L.2
Chirgwin, J.M.3
Guise, T.A.4
-
39
-
-
0030754093
-
Purification and characterization of novel heparin-binding growth factors in uterine secretory fluids. Identification as heparin-regulated Mr 10,000 forms of connective tissue growth factor
-
Brigstock DR, Steffen CL, Kim GY, Vegunta RK, Diehl JR and Harding PA: Purification and characterization of novel heparin-binding growth factors in uterine secretory fluids. Identification as heparin-regulated Mr 10,000 forms of connective tissue growth factor. J Biol Chem 272: 20275-20282, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 20275-20282
-
-
Brigstock, D.R.1
Steffen, C.L.2
Kim, G.Y.3
Vegunta, R.K.4
Diehl, J.R.5
Harding, P.A.6
-
40
-
-
11144229668
-
Cyr61 suppresses growth of human endometrial cancer cells
-
Chien W, Kumagai T, Miller CW, et al: Cyr61 suppresses growth of human endometrial cancer cells. J Biol Chem 279: 53087-53096, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 53087-53096
-
-
Chien, W.1
Kumagai, T.2
Miller, C.W.3
|