Liver Transplantation in Pigs: NO, Oxygen Free Radicals, Pulmonary Hemodynamics

Journal of Surgical Research

Volumn 149, Issue 2, 2008, Pages 231-235

  Kostopanagiotou, Georgia ^a   Tierris, John ^a   Arkadopoulos, Nikolaos ^a   Theodoraki, Kassiani ^a   Deliconstantinos, George ^a   Matsota, Paraskevi ^a   Smyrniotis, Vasilios ^a   Pandazi, Ageliki ^a  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

liver transplantation; nitric oxide; orthotopic; oxygen free radicals; pulmonary hemodynamics; pulmonary hypertension

Indexed keywords

ANTIOXIDANT; NITRIC OXIDE; OXYGEN RADICAL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMOLUMINESCENCE; CORRELATION ANALYSIS; HEART INDEX; HEART OUTPUT; LAPAROTOMY; LIVER TRANSPLANTATION; LUNG ARTERY PRESSURE; LUNG HEMODYNAMICS; LUNG VASCULAR RESISTANCE; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY OCCLUSION PRESSURE; PULMONARY HYPERTENSION; REPERFUSION; SPECTROSCOPY; SWINE; SYSTEMIC VASCULAR RESISTANCE;

ANIMALS; HEMODYNAMICS; LIVER TRANSPLANTATION; NITRIC OXIDE; PULMONARY CIRCULATION; REACTIVE OXYGEN SPECIES; SWINE;

EID: 51049108178     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2007.10.017     Document Type: Article

References (24)

1. Reich D., Wood R., Emre S., et al. Association of intraoperative hypotension and pulmonary hypertension with adverse outcomes after orthotopic liver transplantation. J Cardiothorac Vasc Anesth 17 (2003) 699
2. Duran F., Piqueras B., Romero M., et al. Pulmonary complications following orthotopic liver transplant. Transplant Int 11 (1998) S255
3. Black S., and Fineman J. Oxidative and nitrosative stress in pediatric pulmonary hypertension: Roles of endothelin-1 and nitric oxide. Vascul Pharmacol 45 (2006) 308
4. Fresquet F., Pourageaud F., Leblais V., et al. Role of reactive oxygen species and gp91phox in endothelial dysfunction of pulmonary arteries induced by chronic hypoxia. Br J Pharmacol 148 (2006) 714
5. Hampl V., and Herget J. Role of nitric oxide in the pathogenesis of chronic pulmonary hypertension. Physiol Rev 80 (2000) 1337
6. Machado R., Londhe Nerkar M., Dweik R., et al. Nitric oxide and pulmonary arterial pressures in pulmonary hypertension. Free Radic Biol Med 37 (2004) 1010
7. Varadarajan R., Golden-Mason L., Young L., et al. Nitric oxide in early ischemia reperfusion injury during human orthotopic liver transplantation. Transplantation 78 (2004) 250
8. Findlay J., Harrison B., Plevak D., and Krowka M. Inhaled nitric oxide reduces pulmonary artery pressures in portopulmonary hypertension. Liver Transpl Surg 5 (1999) 381
9. Molmenti P., Ramsay M., Ramsay K., et al. Epoprostenol and nitric oxide therapy for severe pulmonary hypertension in liver transplantation. Transplant Proc 33 (2001) 1332
10. Girardis M., Pasqualotto A., Colo F., et al. Severe hypoxemia and pulmonary hypertension during orthotopic liver transplantation: A successful use of inhaled nitric oxide. Intensive Care Med 25 (1999) 638
11. Gong J.P., Tu B., Wang W., et al. Protective effect of nitric oxide induced by ischemic preconditioning on reperfusion injury of rat liver graft. World J Gastroenterol 10 (2004) 73
12. Lichtman S.N., and Lemasters J.J. Role of cytokines and cytokine producing cells in reperfusion injury to the liver. Semin Liver Dis 19 (1999) 171
13. Palmes D., Minin E., Budny T., et al. The endothelin/nitric oxide balance determines small-for-size liver injury after reduced size rat liver transplantation. Virchows Arch 447 (2005) 731
14. Battista S., Mengozzi G., Bar F., et al. Nitric oxide level profile in human liver transplantation. Dig Dis Sci 47 (2002) 528
15. Kiechle F.L., and Malinski T. Nitric oxide. Biochemistry, pathophysiology, and detection. Am J Clin Pathol 100 (1993) 567
16. Deliconstantinos G., Villiotou V., and Stavrides J.C. Alterations of nitric oxide synthase and xanthine oxidase activities of human keratinocytes by ultraviolet B radiation. Potential role for peroxynitrite in skin inflammation. Biochem Pharmacol 51 (1996) 1727
17. Veloso C.A., Boin I.F.C., Dragosavac D., et al. Retrospective analysis of patients who developed pulmonary hypertension during the early postoperative period after liver transplantation. Transplant Proc 36 (2004) 938
18. Stenqvist O., Olausson M., and Karlsen K.L. Luxury lung perfusion in end-stage liver disease during liver transplantation. Acta Anaesthesiol Scand 43 (1999) 447
19. Acosta F., Sansano T., and Palenciano C.G. Portopulmonary hypertension and liver transplantation: Hemodynamic consequences at reperfusion. Transplant Proc 37 (2005) 3865
20. Huk I., Nanobashvili J., Neumayer C., et al. L-arginine treatment alters the kinetics of nitric oxide and superoxide release and reduces ischemia/reperfusion injury in skeletal muscle. Circulation 96 (1997) 667
21. Grobe A.C., Wells S.M., Benavidez E., et al. Increased oxidative stress in lambs with increased pulmonary blood flow and pulmonary hypertension: Role of NADPH oxidase and endothelial NO synthase. Am J Physiol Lung Cell Mol Physiol 290 (2006) 1069
22. Franco-Gou R., Rosello-Catafau J., and Peralta C. Protection against lung damage in reduced-size liver transplantation. Crit Care Med 34 (2006) 1506
23. Castro M., Krowka M.J., Schroeder D.R., et al. Frequency and clinical implications of increased pulmonary artery pressures in liver transplant patients. Mayo Clin Proc 71 (1996) 543
24. Kuo P.C., Plotkin J.S., Gaine S., et al. Portopulmonary hyper-tension and the liver transplant candidate. Transplantation 67 (1999) 1087