Risk factors and molecular analysis of panton-valentine leukocidin-positive methicillin-resistant staphylococcus aureus colonization in healthy children

Pediatric Infectious Disease Journal

Volumn 27, Issue 8, 2008, Pages 713-718

  Lo, Wen Tsung ^a   Lin, Wei Jen ^a   Tseng, Min Hua ^a   Wang, Sheng Ru ^a   Chu, Mong Ling ^a   Wang, Chih Chien ^a  

^a TRI SERVICE GENERAL HOSPITAL   (Taiwan)

Author keywords

Methicillin resistant Staphylococcus aureus; Nasal colonization; Panton Valentine leukocidin; Staphylococcal cassette chromosome mec; Taiwan

Indexed keywords

PANTON VALENTINE LEUKOCIDIN; BACTERIAL DNA; BACTERIAL TOXIN; EXOTOXIN; LEUKOCIDIN; PANTON-VALENTINE LEUKOCIDIN;

ANTIBIOTIC SENSITIVITY; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL STRAIN; CASE CONTROL STUDY; CHILD; FEMALE; GENE CASSETTE; HUMAN; INFANT; KINDERGARTEN; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NORMAL HUMAN; NOSE SMEAR; PRIORITY JOURNAL; RISK FACTOR; TAIWAN; CLASSIFICATION; DRUG EFFECT; GENETICS; HETEROZYGOTE; ISOLATION AND PURIFICATION; MICROBIOLOGY; NOSE CAVITY; PENICILLIN RESISTANCE; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PREVALENCE; PULSED FIELD GEL ELECTROPHORESIS; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION;

BACTERIAL TOXINS; CARRIER STATE; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; DNA, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; EXOTOXINS; FEMALE; HUMANS; INFANT; LEUKOCIDINS; MALE; METHICILLIN RESISTANCE; NASAL CAVITY; POLYMERASE CHAIN REACTION; PREVALENCE; RISK FACTORS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; TAIWAN;

EID: 51049086618     PISSN: 08913668     EISSN: 15320987     Source Type: Journal    
DOI: 10.1097/INF.0b013e31816f63b5     Document Type: Article

References (41)

1. Lowy FD. Staphylococcus aureus infections. N Engl J Med. 1998;339: 520-532.
2. Herold BC, Immergluck LC, Maranan MC, et al. Community-acquired methicillin-resistant Staphylococcus aureus in children with no identified predisposing risk. JAMA. 1998;279:593-598.
3. Adem PV, Montgomery CP, Husain AN, et al. Staphylococcus aureus sepsis and the Waterhouse-Friderichsen syndrome in children. N Engl J Med. 2005;353:1245-1251.
4. Mongkolrattanothai K, Boyle S, Kahana MD, Daum RS. Severe Staph- ylococcus aureus infections caused by clonally related community-acquired methicillin-susceptible and methicillin-resistant isolates. Clin Infect Dis. 2003;37:1050-1058.
5. Miller LG, Perdreau-Remington F, Rieg G, et al. Necrotizing fasciitis caused by community-associated methicillin-resistant Staphylococcus aureus in Los Angeles. N Engl J Med. 2005;352:1445-1453.
6. Centers for Disease Control and Prevention. Four pediatric deaths from community-acquired methicillin-resistant Staphylococcus aureus: Minnesota and North Dakota, 1997-1999. JAMA. 1999;282:1123-1125.
7. Ma XX, Ito T, Tiensasitorn C, et al. Novel type of staphylococcal cassette chromosome mec identified in community-acquired methicillin-resistant Staphylococcus aureus strains. Antimicrob Agents Chemother. 2002;46:1147-1152.
8. Daum RS, Ito T, Hiramatsu K, et al. A novel methicillin-resistant cassette in community-acquired methicillin-resistant Staphylococcus au-reus isolates of diverse genetic backgrounds. J Infect Dis. 2002;186: 1344-1347.
9. Ito T, Ma XX, Takeuchi F, Okuma K, Yuzama H, Hiramatsu K. Novel type V staphylococcal cassette chromosome mec driven by a novel cassette chromosome recombinase, ccrC.. Antimicrob Agents Chemother. 2004;48:2637-2651.
10. Boyle-Vavra S, Ereshefsky B, Wang CC, Daum RS. Successful multiresistant community-associated methicillin-resistant Staphylococcus aureus lineage from Taipei, Taiwan, that carries either the novel staph-ylococcal chromosome cassette mec (SCCmec) type VT or SCCmec type IV. J Clin Microbiol. 2005;43:4719-4730.
11. Boyle-Vavra S, Daum RS. Community-acquired methicillin-resistant Staphylococcus aureus: the role of Panton-Valentine leukocidin. Lab Invest. 2007;87:3-9.
12. Lina G, Piémont Y, Godail-Gamot F, et al. Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia. Clin Infect Dis. 1999;29:1128-1132.
13. Gillet Y, Issartel B, Vanhems P, et al. Association between Staphylo-coccus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent pa-tients. Lancet. 2002;359:753-759.
14. Labandeira-Rey M, Couzon F, Boisset S, et al. Staphylococcus aureus Panton-Valentine leukocidin causes necrotizing pneumonia. Science. 2007;315:1130-1133.
15. Voyich JM, Otto M, Mathema B, et al. Is Panton-Valentine leukocidin the major virulence determinant in community-acquired methicillin-resistant Staphylococcus aureus disease? J Infect Dis. 2006;194:1761-1770.
16. Vandenesch F, Naimi T, Enright MC, et al. Community-acquired me-thicillin-resistant Staphylococcus aureus carrying Panton-Valentine leukocidin genes: worldwide emergence. Emerg Infect Dis. 2003;9:978-984.
17. Tristan A, Bes M, Meugnier H, et al. Global distribution of Panton-Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus, 2006. Emerg Infect Dis. 2007;13:594-600.
18. Okuma K, Iwakawa K, Turnidge JD, et al. Dissemination of new methicillin-resistant Staphylococcus aureus clones in the community.J Clin Microbiol. 2002;40:4289-4294.
19. Saiman L, O'Keefe M, Graham PL III, et al. Hospital transmission of community-acquired methicillin-resistant Staphylococcus aureus among postpartum women. Clin Infect Dis. 2003;37:1313-1319.
20. Chalumeau M, Bidet P, Lina G, et al. Transmission of Panton-Valentine leukocidin-producing Staphylococcus aureus to a physician during re-suscitation of a child. Clin Infect Dis. 2005;41:e29-e30.
21. Ellis MW, Hospenthal DR, Dooley DP, Gray PJ, Murray CK. Natural history of community-acquired methicillin-resistant Staphylococcus au-reus colonization and infection in soldiers. Clin Infect Dis. 2004;39:971-979.
22. Lo WT, Lin WJ, Tseng MH, Wang SR, Chu ML, Wang CC. Community-acquired methicillin-resistant Staphylococcus aureus in children, Taiwan. Emerg Infect Dis. 2006;12:1267-1270.
23. Nakamura MM, Rohling KL, Shashaty M, Lu H, Tang YW, Edwards KM. Prevalence of methicillin-resistant Staphylococcus aureus nasal carriage in the community pediatric population. Pediatr Infect Dis J. 2002;21:917-922.
24. Creech II CB, Kernodle DS, Alsentzer A, Wilson C, Edwards KM. Increasing rate of nasal carriage of methicillin-resistant Staphylococcus aureus in healthy children. Pediatr Infect Dis J. 2005;24:617-621.
25. National Committee for Clinical Laboratory Standards. Methods for disk diffusion: approved standard M2-A8: performance standards for antimi-crobial disk susceptibility tests. Wayne, PA: The Committee; 2003.
26. National Committee for Clinical Laboratory Standards. Performance standards for antimicrobial susceptibility testing: 14th informational supplement. NCCLS document M100-S14. Wayne, PA: The Committee; 2004.
27. Shortridge VD, Flamm RK, Ramer N, Beyer J, Tanaka SK. Novel mechanism of macrolide resistance in Streptococcus pneumoniae. Diagn Microbiol Infect Dis. 1996;26:73-78.
28. Almer LS, Shortridge VD, Nilius AM, et al. Antimicrobial susceptibility and molecular characterization of community-acquired methicillin-resistant Staphylococcus aureus. Diagn Microbiol Infect Dis. 2002;43:225-232.
29. Jarraud S, Cozon G, Vandenesch F, Bes M, Etienne J, Lina G. Involvement of enterotoxins G and I in staphylococcal toxic shock syndrome and staphylococcal scarlet fever. J Clin Microbiol. 1999;37:2446-2449.
30. Oliveira DC, de Lencastre H. Multiplex PCR strategy for rapid identification of structural types and variants of the mec element in methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother.2002;46:2155-2161.
31. McDougal LK, Steward CD, Killgore GE, Chaitram JM, McAllister SK, Tenover FC. Pulsed-field gel electrophoresis typing of oxacillin-resistant Staphylococcus aureus isolates from the United States: establishing a national database. J Clin Microbiol. 2003;41:5113-5120.
32. Tenover FC, Arbeit RD, Goering RV, et al. Interpreting chromosomal DNA restriction patterns produced by pulse-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol. 1995;33:2233-2239.
33. Wu KC, Chiu HH, Wang JH, et al. Characteristics of community-acquired methicillin-resistant Staphylococcus aureus in infants and children without known risk factors. J Microbiol Immunol Infect. 2002;35:53-56.
34. Wang CC, Lo WT, Chu ML, Siu LK. Epidemiological typing of community-acquired methicillin-resistant Staphylococcus aureus isolates from children in Taiwan. Clin Infect Dis. 2004;39:481-487.
35. Chen CJ, Huang YC, Chiu CH, Su LH, Lin TY. Clinical features and genotyping analysis of community-acquired methicillin-resistant Staph-ylococcus aureus infections in Taiwanese children. Pediatr Infect Dis J. 2005;24:40-45.
36. Hisata K, Kuwahara-Arai K, Yamanoto M, et al. Dissemination of methicillin-resistant staphylococci among healthy Japanese children. J Clin Microbiol. 2005;43:3364-3372.
37. Hussain FM, Boyle-Vavra S, Bethel CD, Daum RS. Current trends in community-acquired methicillin-resistant Staphylococcus aureus at a tertiary care pediatric facility. Pediatr Infect Dis J. 2000;19:1163-1166.
38. Fergie JE, Purcell K. Community-acquired methicillin-resistant Staphy- lococcus aureus infections in South Texas children. Pediatr Infect Dis J. 2001;20:860-863.
39. Liu YC, Huang WK, Huang TS, Kunin CM. Extent of antibiotic use in Taiwan shown by antimicrobial activity in urine. Lancet. 1999;354:1360.
40. Hsueh PR, Liu CY, Luh KT. Current status of antimicrobial resistance in Taiwan. Emerg Infect Dis. 2002;8:132-137.
41. Chang SC, Shiu MN, Chen TJ. Antibiotic usage in primary care units inTaiwan after the institution of national health insurance. Diagn Microbiol Infect Dis. 2001;40:137-143.