Agonistic at 1 receptor autoantibody increases in serum of patients with refractory hypertension and improves Ca2+ mobilization in cultured rat vascular smooth muscle cells

Cellular and Molecular Immunology

Volumn 5, Issue 3, 2008, Pages 209-217

  Zhu, Feng ^a   Sun, Yanxiang ^a   Liao, Yuhua ^a   Wei, Yumiao ^a   Chen, Ming ^a   Wang, Min ^a   Zhou, Zihua ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

angiotensin II receptor type 1; antibody; Autoimmunity; hypertension

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR ANTAGONIST; AUTOANTIBODY; CALCIUM; LOSARTAN;

ANIMAL; ARTICLE; BLOOD; CELL CULTURE; CELL PROLIFERATION; CYTOLOGY; DOSE RESPONSE; DRUG POTENTIATION; FEMALE; HUMAN; HYPERTENSION; IMMUNOLOGY; MALE; METABOLISM; MIDDLE AGED; RAT; SPRAGUE DAWLEY RAT; VASCULAR SMOOTH MUSCLE;

ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; AUTOANTIBODIES; CALCIUM; CELL PROLIFERATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; FEMALE; HUMANS; HYPERTENSION; LOSARTAN; MALE; MIDDLE AGED; MUSCLE, SMOOTH, VASCULAR; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ANGIOTENSIN, TYPE 1;

EID: 51049084909     PISSN: 16727681     EISSN: None     Source Type: Journal    
DOI: 10.1038/cmi.2008.26     Document Type: Article

References (34)

1. Liu LS, Gong LS. Prevention and treatment of high blood pressure in China part I. Chin J Hyper. 2000;12:94-101.
2. Alper AB J, Calhoun DA. Contemporary management of refractory hypertension. Curr Hypertensn Rep. 1999;1:402-407.
3. Isaksson H, Ostergren J. Prognosis in therapy-resistant hypertension. J Int Med. 1994;236:643-649.
4. Goodfriend TL, Calhoun DA. Resistant hypertension, obesity, sleep apnea, and aldosterone: theory and therapy. Hypertension. 2004;43:518-524. (Pubitemid 38282420)
5. The Seventh Report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure. JAMA. 2003;289:2560-2572.
6. 1 receptor. J Clin Invest. 1999;103:945-952. (Pubitemid 29169601)
7. 1) in patients with hypertension. J Hypertens. 2000;18:945-953. (Pubitemid 30459497)
8. 1-receptor and α1-adrenergic receptor in patients with hypertension. Hypertens Res. 2002;25:641-646.
9. Zhou ZH, Liao YH, Wang M, et al. Role of autoantibodies against angiotensin II type 1 receptor in hypertensive patients with cerebral sroke. Chin J Clin Rehabil. 2004;8:6944-6949.
10. 1 receptor agonistic antibodies from preeclamptic patients cause vascular cells to express tissue factor. Circulation. 2000;101:2382-2387. (Pubitemid 30329128)
11. 1 Receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidase. Circulation. 2003;107:1632-1639. (Pubitemid 36401560)
12. 2+ mobilization through angiotensin receptor activation. Circulation. 2004;110:1612-1619. (Pubitemid 39297984)
13. Horowitz A, Menice CB, R Laporte, KG Morgan. Mechanisms of smooth muscle contraction. Physiol Rev. 1996;76:967-1003. (Pubitemid 26346813)
14. Schwartz, SM, Ross R. Cellular proliferation in atherosclerosis and hypertension. Prog Cardiovasc Dis. 1984;26:355-372. (Pubitemid 14170168)
15. Berk BC, Vekshtein V, Gordon HM, Tsuda T. Angiotensin II-stimulated protein synthesis in cultured vascular smooth muscle cells. Hypertension. 1989;13:305-314. (Pubitemid 19099600)
16. Mauzy CA, Hwang O, Egloff M, Wu LH, Chung FZ. Cloning, expression, and characterization of a gene encoding the human angiotensin II type 1A receptor. Biochem Biophys Res Commun. 1992;186:277-284.
17. Furuta H, Guo DF, Inagami T. Molecular cloning and sequencing of the gene encoding human angiotensin II type 1 receptor. Biochem Biophys Res Commun. 1992;183:8-13.
18. Gopalakrishnan V, Xu Y, Sulakhe P V, et al. Vasopressin (V1) receptor characteristics in rat aortic smooth muscle cells. Am J Physiol. 1991;261: H1927-H1936.
19. Minta A, Kao J P, Tsien RY. Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores. J Biol Chem. 1989;264:8171-8178. (Pubitemid 19137304)
20. Cobbold PH, Rink TJ. Fluorescence and bioluminescence measurement of cytoplasmic free calcium. Biochem J. 1987;248:313-328. (Pubitemid 18001883)
21. Berk BC, Corson MA. Angiotensin II signal transduction in vascular smooth muscle: role of tyrosine kinases. Circ Res. 1997;80:607-616. (Pubitemid 27181343)
22. Touyz RM, Schiffrin EL. Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells. Pharmacol Rev. 2000;52:639-672.
23. Muller DN, Dechend R, Mervaala EMA, et al. NF-κB inhibition ameliorates angiotensin II-induced inflammatory damage in rats. Hypertension. 2000;35:193-201. (Pubitemid 30054172)
24. Kranzhöfer R, Schmidt J, Pfeiffer CAH, Hagl S, Libby P, Kübler W. Angiotensin induces inflammatory activation of human vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 1999;19:1623-1629. (Pubitemid 29323820)
25. 1 receptor autoantibodies and monocyte stimulation in hypertensive patients. Am J Hypertens. 2003;16:827-833. (Pubitemid 37204679)
26. 1-receptor peptide. Heart Vessels. 2005;20:153-158. (Pubitemid 41031013)
27. Cuspidi C, Macca G, Sampieri L, et al. High prevalence of cardiac and extracardiac target organ damage in refractory hypertension. J Hypertens. 2001;19:2063-2070. (Pubitemid 33035812)
28. Ram CV. Management of refractory hypertension. Am T Ther. 2003;10:122-126.
29. 1 receptors. Zhongguo Ye Jin Gong Ye Yi Xue Zha Zhi. 2001;18:65-69.
30. Homuth V, Stabroth C, Wallukat G, et al. Agonistic antibodies against the α1-receptor in patients with refractory hypertension and their removal by immune adsorption. Hypertonie. 2003.
31. Masuda MO, Levin M, De Oliveira SF, et al. Functionally active cardiac antibodies in chronic Chagas' disease are specifically blocked by Trypanosoma cruzi antigens. FASEB J. 1998;12:1551-1558. (Pubitemid 28506724)
32. Schwimmbeck PL, Dyrberg T, Drachman DB, Oldstone MB. Molecular mimicry and myasthenia gravis. An autoantigenic site of the acetylcholine receptor α-subunit that has biologic activity and reacts immunochemically with herpes simplex virus. J Clin Invest. 1989;84:1174-1180. (Pubitemid 19247588)
33. Dragun D, Muller DN, Brasen JH, et al. Angiotensin II Type 1-receptor activating antibodies in renal-allograft rejection. N Engl J Med. 2005;352:558-569. (Pubitemid 40204669)
34. Rioux JD, Abbas AK. Paths to understanding the genetic basis of autoimmune disease. Nature. 2005;435:584-589. (Pubitemid 40825497)