Arterial structural changes in rats immunized by AT1-receptor peptide

Heart and Vessels

Volumn 20, Issue 4, 2005, Pages 153-158

  Wang, Bin ^a   Liao, Yu Hua ^a   Zhou, Zihua ^a   Li, Liudong ^a   Wei, Fen ^a   Wang, Ming ^a   Wei, Yumiao ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Antibody; Arterial structure; AT1 receptor; Proliferation; Smooth muscle cell

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; BROXURIDINE; LOSARTAN; MESSENGER RNA; PROTEIN ANTIBODY; PROTEIN C FOS; PROTEIN C JUN; SYNTHETIC PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY AFFINITY; ANTIBODY DETECTION; AORTA; ARTICLE; BLOOD PRESSURE MONITORING; CELL CULTURE; CELL CYCLE; CELL PROLIFERATION; CHROMATOGRAPHY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART RATE; HYPERTENSION; IMMUNIZATION; MALE; MESENTERIC ARTERY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; RAT STRAIN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; STUDENT T TEST; UPREGULATION; VASCULAR RESISTANCE; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

ANIMALS; ANTIBODY FORMATION; BLOOD PRESSURE; BROMODEOXYURIDINE; CELL CYCLE; CELL DIVISION; CELLS, CULTURED; HEART RATE; IMMUNIZATION; MALE; MESENTERIC ARTERIES; MUSCLE, SMOOTH, VASCULAR; PROTO-ONCOGENE PROTEINS C-FOS; PROTO-ONCOGENE PROTEINS C-JUN; RATS; RATS, WISTAR; RECEPTOR, ANGIOTENSIN, TYPE 1;

EID: 22744448332     PISSN: 09108327     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00380-005-0825-9     Document Type: Article

References (11)

1. ML Fu H Herlitz G Wallukat E Hilme T Hedner J Hoebeke A Hjalmarson 1996 Non-desensitized positive chronotropic effect of anti-angiotension II receptor autoantibodies in a patient with malignant hypertension (abstract Circulation 94 4046a
2. G Wallukat V Homuth T Fischer C Lindschau B Horstkamp A Jüpner E Baur E Nissen K Vetter D Neichel JW Dudenhausen H Haller FC Luft 1999 Patients with preeclampsia develop agonistic antibodies against the angiotension AT1 receptor J Clin Invest 103 945-952
3. 1-receptor and alpha1-adrenergic receptor in patients with hypertension Hypertens Res 25 641-646
4. Fu ML, Leung PS, Wallukat G, Bergstrom G, Fu H, Schulze W, Herlitz H (1999) Agonist-like activity of antibodies to angiotensin II receptor subtype 1 (AT1) from rats immunized with AT1 receptor peptide. Blood Press 8:317-324
5. ML Fu H Herlitz W Schulze G Wallukat P Micke P Eftekhari KG Sjogren A Hjalmarson W Muller-Esterl J Hoebeke 2000 Autoantibodies against the angiotensin receptor (AT1) in patients with hypertension J Hypertens 18 945-953
6. JM Zhi LY Zhao XY Jiao RR Zhao 2002 Changes in autoantibodies against cardiovascular AT1-receptor during development of renovascular hypertension in rats Sheng Li Xue Bao 54 317-320
7. YS Luo YH Liao M Wang YM Wei JH Dong JP Wang YP Lu 2001 Expermental study of At1-receptor peptide induced myocardial immune damage in rats J Tongji Med Univ 21 202-204
8. J Li B Zhang Z Huang S Wang C Tang J Du 2004 Taurine prevents beta-glycerophosphate-induced muscle cells Heart Vessels 19 125-131
9. M Rhian L Schiffrin Touyz and Ernesto 2000 Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells Hypertension 52 639-672
10. H Gavras HR Brunner 2001 Role of angiotensin and its inhibition in hypertension, ischemia heart disease and heart failure Hypertension 37 342
11. B Folkow 1995 The structural factor in hypertension, with special emphasis in the altered geometric design of the systemic. In: JH Laragh BM Brenner (eds) Hypertension: Physiology, diagnosis, and management Raven Press New York 31