Investigations on the effects of NMR experimental conditions in human urine and serum metabolic profiles

2nd International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2008

Volumn , Issue , 2008, Pages 2236-2239

  Cao, Hongting ^a   Dong, Jiyang ^a   Cai, Congbo ^a   Chen, Zhong ^a  

^a XIAMEN UNIVERSITY   (China)

Author keywords

^{1< sup>H NMR spectra; Metabonomics; Saturation power; Temperature}

Indexed keywords

BIOCOMMUNICATIONS; BIOINFORMATICS; BIOMEDICAL ENGINEERING; INFORMATION SCIENCE; ISOMERS; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RESONANCE;

¹H NMR SPECTRA; EXPERIMENTAL CONDITIONS; METABONOMICS; SATURATION POWER; TEMPERATURE;

BODY FLUIDS;

EID: 50949131431     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/ICBBE.2008.890     Document Type: Conference Paper

References (9)

1. J. K. Nicholson, J. C. Lindon, and E. Holmes, "'Metabonomics: understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data", Xenobiotica, Taylor & Francis Ltd, London, 1999, pp. 1181-1189.
2. Orla Teahan, Simon Gamble,Elaine Holmes,Jonathan Waxman,J. K. Nicholson, Charlotte Bevan, and Hector C. Keun, "Impact of Analytical Bias in Metabonomic Studies of Human Blood Serum and Plasma", Analytical Chemistry,American Chemical Society,Washington, DC, 2006, pp.4307-4318
3. Michael Lauridsen,Steen H. Hansen,Jerzy W. Jaroszewski, and Claus Cornett, "Human Urine as Test Material in 1H NMR-Based Metabonomics: Recommendations for Sample Preparation and Storage". Analytical Chemistry, American Chemical Society, Washington, DC, 2007, pp. 1181-1186
4. H.C. Keun, T.M. Ebbels, H. Antti, M.E. Bollard, O. Beckonert,G. Schlotterbeck, H. Senn, U. Niederhauser, E. Holmes, J.C. Lindon,J.K. Nicholson, "Analytical reproducibility in 1H NMR-based metabonomic urinalysis", Chemical Research in Toxicology, American Chemical Society, Washington, DC, 2002 , pp.1380 1386.
5. Bao D. Nguyen, Xi Meng, Kevin J. Donovan, A.J. Shaka, "SOGGY: Solvent-optimized double gradient spectroscopy forwater suppression. A comparison with some existing techniques", Journal of Magnetic Resonance , Elsevier B.V. , Amsterdam, 2007 pp.263 274
6. Jeremy K. Nicholson and Peta J. D. Foxall, "750 MHz 1H and 1H-13C NMR Spectroscopy of Human Blood Plasma.", Analytical Chemistry, American Chemical Society, Washington,DC, 1996, pp. 793-811
7. P.J.D. Foxall, J.A. Parkinson, I.H. Sadler, J.C. Lindon, J.K.Nicholson, "Analysis of biological-fluids using 600MHz proton NMR-spectroscopy- application of homonuclear 2-dimensional Jresolved spectroscopy to urine and blood plasma sterling for spectral simplification and assignment", Journal of Pharmaceutical and Biomedical Analysis, Elsevier B.V. , Amsterdam,1993, pp.21 31.
8. Nelly Araní bar , Karl-Heinz Ott, Vikram Roongta, Luciano Mueller, "Metabolomic analysis using optimized NMR and statistical methods.", Analytical biochemistry , Elsevier B.V. , Amsterdam, 2006, pp.62 70
9. Maili Liu, Xi-an Mao, Chaohui Ye, He Huang, J. K. Nicholson, John C. Lindon, "Improved WATERGATE Pulse Sequences for Solvent Suppression in NMR Spectroscopy. Journal of Magnetic Resonance", Elsevier B.V. , Amsterdam, 1998, pp.125-129.