Role of lipid rafts in agrin-elicited acetylcholine receptor clustering

Chemico-Biological Interactions

Volumn 175, Issue 1-3, 2008, Pages 64-67

  Pato, C ^a   Stetzkowski Marden, F ^a   Gaus, K ^b   Recouvreur, M ^a   Cartaud, A ^a   Cartaud, J ^a  

^a INSTITUT JACQUES MONOD   (France)

^b MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

Author keywords

Lipid rafts; Neuromuscular junction; Nicotinic acetylcholine receptor

Indexed keywords

ACTIN; ACTIN RELATED PROTEIN 2; ACTIN RELATED PROTEIN 3; AGRIN; BUFFER; CALCIUM ION; CHOLESTEROL; CHOLINERGIC RECEPTOR; DETERGENT; GANGLIOSIDE GM1; MAGNESIUM ION; MUSCLE SPECIFIC KINASE; NEURAL WISKOTT ALDRICH SYNDROME PROTEIN; PHOSPHOTRANSFERASE; RAPSYN; SPHINGOLIPID; SYNTROPHIN; TRITON X 100; UNCLASSIFIED DRUG;

ACTIN POLYMERIZATION; ALKALINITY; ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONFOCAL MICROSCOPY; CYTOSKELETON; DETERGENT RESISTANT MEMBRANE; ENZYME ACTIVATION; EXTRACTION; IMAGING SYSTEM; LIPID RAFT; MYOTUBE; NEUROMUSCULAR SYNAPSE; NONHUMAN; RAT; TWO PHOTON LAURDAN CONFOCAL IMAGING;

ACTINS; AGRIN; ANIMALS; LIPID METABOLISM; MICE; RECEPTORS, CHOLINERGIC;

EID: 50949129177     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2008.03.020     Document Type: Article

References (15)

1. Stetzkowski-Marden F., Gaus K., Recouvreur M., Cartaud A., and Cartaud J. Agrin elicits membrane condensation at sites of acetylcholine receptor clusters in C2C12 myotubes. J. Lipid Res. 47 (2006) 2121-2133
2. Gaus K., Zech T., and Harder T. Visualizing membrane macrodomains by Laurdan 2-photon microscopy. Mol. Membr. Biol. 23 (2006) 41-48
3. Gaus K., Rodriguez M., Ruberu K.R., Gelissen I., Sloane T.M., Kritharides L., and Jessup W. Domain specific lipid distribution in macrophage plasma membrane. J. Lipid Res. 46 (2005) 1526-1538
4. Song K.S., Li S., Okamoto T., Quilliam L.A., Sargiacomo M., and Lisanti M.P. Co-purification and direct interaction of Ras with caveolin, an integral membrane protein of caveolae microdomains. Detergent-free purification of caveolae microdomains. J. Biol. Chem. 271 (1996) 9690-9697
5. Pike L.J., and Miller J.M. Cholesterol depletion delocalizes phosphatidylinositol bisphosphate and inhibits hormone-stimulated phosphatidylinositol turnover. J. Biol. Chem. 273 (1998) 22298-22304
6. Marchand S., Devillers-Thiéry A., Pons S., Changeux J.P., and Cartaud J. Rapsyn escorts the nicotinic acetylcholine receptor along the exocytic pathway via association with lipid rafts. J. Neurosci. 20 (2002) 8891-8901
7. Campagna J.A., and Fallon J. Lipid rafts are involved in C95 (4,8) agrin fragment-induced acetylcholine receptor clustering. Neuroscience 138 (2006) 123-132
8. Zhu D., Xiong W.C., and Mei L. Lipid rafts serve as a signaling platform for nicotinic acetylcholine receptor clustering. J. Neurosci. 26 (2006) 4841-4851
9. Willmann R., Pun S., Stallmach L., Sadasivam G., Santos A.F., Caroni P., and Fuhrer C. Cholesterol and lipid microdomains stabilize the postsynapse at the neuromuscular junction. EMBO J. 25 (2006) 4050-4056
10. Cemerski S., and Shaw A. Immune synapse in T-cell activation. Curr. Opin. Immunol. 18 (2006) 298-304
11. Dai Z., Luo X., Xie H., and Peng H.B. The actin-driven movement and formation of acetylcholine receptor clusters. J. Cell Biol. 150 (2000) 1321-1334
12. Weston C., Yee B., Hod E., and Prives J. Agrin-induced acetylcholine receptor clustering is mediated by small guanosine triphosphatases Rac and Cdc42. J. Cell Biol. 150 (2000) 205-212
13. Luo Z.G., Wang Q., Zhou J.Z., Wang J., Luo Z., Liu M., He X., Wynshaw-Boris A., Xiong W.C., Lu B., and Mei L. Regulation of AChR clustering by dishevelled interacting with MuSK and PAK1. Neuron 35 (2002) 489-505
14. Weston C., Gordon C., Teressa G., Hod E., Ren X.D., and Prives J. Cooperative regulation by Rac and Rho of agrin-induced acetylcholine receptor clustering in muscle cells. J. Biol. Chem. 278 (2003) 6450-6455
15. Rozelle A.L., Machesky L.M., Yamamoto M., Driessens M.H.E., Insall R.H., Roth M.G., Luby-Phelps K., Marriott G., Hall A., and Yin H.L. Phosphatidylinositol 4,5-bisphosphate induces actin-based movement of raft-enriched vesicles through WASP-Arp2/3. Curr. Biol. 10 (2000) 311-320