Emergence and acquisition of fluoroquinolone-resistant gram-negative bacilli in the intestinal tracts of mice treated with fluoroquinolone antimicrobial agents

Antimicrobial Agents and Chemotherapy

Volumn 52, Issue 9, 2008, Pages 3457-3460

  Pultz, Michael J ^a   Nerandzic, Michelle M ^a   Stiefel, Usha ^a   Donskey, Curtis J ^a  

^a LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; CLINDAMYCIN; GATIFLOXACIN; LEVOFLOXACIN; MOXIFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL STRAIN; CONTROLLED STUDY; ENTEROBACTER INFECTION; KLEBSIELLA PNEUMONIAE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTI-BACTERIAL AGENTS; CLINDAMYCIN; DRUG RESISTANCE, BACTERIAL; FLUOROQUINOLONES; GRAM-NEGATIVE BACTERIA; INTESTINES; KLEBSIELLA PNEUMONIAE; MICE; MICROBIAL SENSITIVITY TESTS;

EID: 50949090943     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.00117-08     Document Type: Article

References (22)

1. Reference deleted.
2. Asensio, A., A. Oliver, P. Gonzalez-Diego, et al. 2000. Outbreak of a multiresistant Klebsiella pneumoniae strain in an intensive care unit: antibiotic use as a risk factor for colonization and infection. Clin. Infect. Dis. 30:55-60.
3. Cohen, A. E., E. Lautenbach, K. H. Morales, and D. R. Linkin. 2006. Fluoroquinolone-resistant Escherichia coli in the long-term care setting. Am. J. Med. 119:958-963.
4. Reference deleted.
5. Donskey, C. J. 2004. The role of the intestinal tract as a reservoir and source for transmission of nosocomial pathogens. Clin. Infect. Dis. 39:219-226.
6. Donskey, C. J. 2006. Antibiotic regimens and intestinal colonization with antibiotic-resistant gram-negative bacilli. Clin. Infect. Dis. 43:S62-S69.
7. Dunbar, L. M., R. G. Wunderink, M. P. Habib, et al. 2003. High-dose, short-course levofloxacin for community-acquired pneumonia: a new treatment paradigm. Clin. Infect. Dis. 37:752-760.
8. Edlund, C., and C. E. Nord. 1999. Effect of quinolones on intestinal ecology. Drugs 58(Suppl. 2):65-70.
9. Edlund, C., G. Beyer, M. Hiemer-Bau, S. Ziege, H. Lode, and C. E. Nord. 2000. Comparative effects of moxifloxacin and clarithromycin on the normal intestinal microflora. Scand. J. Infect. Dis. 32:81-85.
10. Freireich, E., E. Gehan, D. Rall, L. Schmidt, and H. Skipper. 1966. Quantitative comparison of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey and man. Cancer Chemother. Rep. 50:219-244.
11. Harbarth, S., A. D. Harris, Y. Carmeli, and M. H. Samore. 2001. Parallel analysis of individual and aggregated data on antibiotic exposure and resistance in gram-negative bacilli. Clin. Infect. Dis. 33:1462-1468.
12. Horcajada, J. P., J. Villa, A. Moreno-Martinez, J. Ruiz, J. A. Martinez, M. Sanchez, E. Soriano, and J. Mensa. 2002. Molecular epidemiology and evolution of resistance to quinolones in Escherichia coli after prolonged administration of ciprofloxacin in patients with prostatitis. J. Antimicrob. Chemother. 49:55-59.
13. Hoyen, C. K., N. J. Pultz, D. L. Paterson, D. C. Aron, and C. J. Donskey. 2003. Effect of parenteral antibiotic administration on establishment of intestinal colonization in mice by Klebsiella pneumoniae strains producing extended-spectrum β-lactamases. Antimicrob. Agents Chemother. 47:3610-3612.
14. Johnson, J. R., M. A. Kuskowski, M. Menard, A. Gajewski, and M. Xercavins. 2006. Similarity between human and chicken Escherichia coli isolates in relation to ciprofloxacin resistance status. J. Infect. Dis. 194:71-78.
15. Joris, J. J., P. M. Van de Leur, E. J. Vollaard, A. J. H. M. Janssen, and A. S. M. Dofferhoff. 1997. Influence of low dose ciprofloxacin on microbial colonization of the digestive tract in healthy volunteers during normal and during impaired colonization resistance. Scand. J. Infect. Dis. 29:297-300.
16. Maslow, J. N., B. Lee, and E. Lautenbach. 2005. Fluoroquinolone-resistant Escherichia coli carriage in long-term care facility. Emerg. Infect. Dis. 11:889-894.
17. Neuhauser, M. M., R. A. Weinstein, R. Rydman, L. H. Danziger, G. Karam, and J. P. Quinn. 2003. Antibiotic resistance among gram-negative bacilli in US intensive care units: implications for fluoroquinolone use. JAMA 289:885-888.
18. Paterson, D. L., L. Mulazimoglu, J. M. Casellas, et al. 2000. Epidemiology of ciprofloxacin resistance and its relationship to extended-spectrum β-lactamase production in Klebsiella pneumoniae isolates causing bacteremia. Clin. Infect. Dis. 30:473-478.
19. Poole, M., J. Anon, M. Paglia, J. Xiang, M. Khashab, and J. Khan. 2006. A trial of high-dose, short-course levofloxacin for the treatment of acute bacterial sinusitis. Otolaryngol. Head Neck Surg. 134:10-17.
20. Richard, P., M. H. Delangle, F. Raffi, E. Espaze, and H. Richet. 2001. Impact of fluoroquinolone administration on the emergence of fluoroquinolone-resistant gram-negative bacilli from gastrointestinal flora. Clin. Infect. Dis. 32:162-166.
21. Sullivan, A., C. Edlund, and C. E. Nord. 2001. Effect of antimicrobial agents on the ecological balance of human microbiota. Lancet Infect. Dis. 1:101-114.
22. Wiener, J., J. P. Quinn, P. A. Bradford, et al. 1999. Multiple antibiotic-resistant Klebsiella and Escherichia coli in nursing homes. JAMA 281:517-523.