Effect of Parenteral Antibiotic Administration on Establishment of Intestinal Colonization in Mice by Klebsiella pneumoniae Strains Producing Extended-Spectrum β-Lactamases

Antimicrobial Agents and Chemotherapy

Volumn 47, Issue 11, 2003, Pages 3610-3612

  Hoyen, Claudia K ^a   Pultz, Nicole J ^b   Paterson, David L ^c   Aron, David C ^b   Donskey, Curtis J ^b  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

^c UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; AZTREONAM; BETA LACTAMASE; CEFEPIME; CEFTAZIDIME; CEFTRIAXONE; CLINDAMYCIN; LEVOFLOXACIN; PIPERACILLIN PLUS TAZOBACTAM;

ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GROWTH; BACTERIAL STRAIN; INOCULATION; INTESTINE; KLEBSIELLA PNEUMONIAE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTI-BACTERIAL AGENTS; BETA-LACTAMASES; COLONY COUNT, MICROBIAL; DRUG RESISTANCE, BACTERIAL; FEMALE; INJECTIONS, SUBCUTANEOUS; INTESTINES; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MICE;

EID: 0242322584     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.47.11.3610-3612.2003     Document Type: Article

References (14)

1. Bodey, G. P., V. Fainstein, I. Garcia, B. Rosenbaum, and Y. Wong. 1983. Effect of broad-spectrum cephalosporins on the microbial flora of recipients. J. Infect. Dis. 148:892-897.
2. Donskey, C. J., T. K. Chowdhry, M. T. Hecker, C. K. Hoyen, J. A. Hanrahan, A. M. Hujer, R. A. Hutton-Thomas, C. C. Whalen, R. A. Bonomo, and L. B. Rice. 2000. Effect of antibiotic therapy on the density of vancomycin-resistant enterococci in the stool of colonized patients. N. Engl. J. Med. 343:1925-1932.
3. Donskey, C. J., J. A. Hanrahan, R. A. Hutton, and L. B. Rice. 1999. Effect of parenteral antibiotic administration on persistence of vancomycin-resistant Enterococcus faecium in the mouse gastrointestinal tract. J. Infect. Dis. 180:384-390.
4. Donskey, C. J., J. A. Hanrahan, R. A. Hutton, and L. B. Rice. 2000. Effect of parenteral antibiotic administration on the establishment of colonization with vancomycin-resistant Enterococcus faecium in the mouse gastrointestinal tract. J. Infect. Dis. 181:1830-1833.
5. Edlund, C., and C. E. Nord. 1999. Effect of quinolones on intestinal ecology. Drugs 58(Suppl. 2):65-70.
6. Freireich, E., E. Gehan, D. Rail, L. Schmidt, and H. Skipper. 1966. Quantitative comparison of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey and man. Cancer Chemother. Reports 50:219-244.
7. Lautenbach, E., J. B. Patel, W. B. Bilker, P. H. Edelstein, and N. O. Fishman. 2001. Extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae: risk factors for infection and impact of resistance on outcomes. Clin. Infect. Dis. 32:1162-1171.
8. Louie, T. J. 1985. Preservation of colonization resistance parameters during empiric therapy with aztreonam in the febrile neutropenic patient. Rev. Infect. Dis. 7(Suppl. 4):S747-S761.
9. Paterson, D. L., and V. L. Yu. 1999. Editorial response: extended-spectrum β-lactamases: a call for improved detection and control. Clin. Infect. Dis. 29:1419-1422.
10. Rahal, J. J., C. Urban, D. Horn, K. Freeman, S. Segal-Maurer, J. Maurer, N. Mariano, S. Marks, J. M. Burns, D. Dominick, and M. Lim. 1998. Class restriction of cephalosporin use to control total cephalosporin resistance in nosocomial Klebsiella. JAMA 280:1233-1237.
11. Rice, L. B., E. C. Eckstein, J. DeVente, and D. M. Shlaes. 1996. Ceftazidime-resistant Klebsiella pneumoniae isolates recovered at the Cleveland Department of Veterans Affairs Medical Center. Clin. Infect. Dis. 23:118-124.
12. van Ogtrop, M. L., H. F. L. Guiot, H. Mattie, and R. van Furth. 1991. Modulation of the intestinal flora of mice by parenteral treatment with broad-spectrum cephalosporins. Antimicrob. Agents Chemother. 35:976-982.
13. Vollaard, E. J., and H. A. L. Clasener. 1994. Colonization resistance. Antimicrob. Agents Chemother. 38:409-414.
14. Wiener, J., J. P. Quinn, P. A. Bradford, R. V. Goering, C. Nathan, K. Bush, and R. A. Weinstein. 1999. Multiple antibiotic-resistant Klebsiella and Escherichia coli in nursing homes. JAMA 281:517-523.