Influence of low dose ciprofloxacin on microbial colonization of the digestive tract in healthy volunteers during normal and during impaired colonization resistance

Scandinavian Journal of Infectious Diseases

Volumn 29, Issue 3, 1997, Pages 297-300

  Van De Leur, Joris J J P M ^a,b   Vollaard, Ernst J ^a   Janssen, Anton J H M ^a   Dofferhoff, Anthonius S M ^a  

^a CANISIUS WILHELMINA HOSPITAL   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; CLINDAMYCIN; QUINOLONE;

ADULT; ANTIBACTERIAL ACTIVITY; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; GASTROINTESTINAL INFECTION; GRAM NEGATIVE BACTERIUM; HUMAN; HUMAN EXPERIMENT; INFECTION RESISTANCE; MALE; NORMAL HUMAN; ORAL DRUG ADMINISTRATION;

EID: 0030871871     PISSN: 00365548     EISSN: None     Source Type: Journal    
DOI: 10.3109/00365549709019046     Document Type: Article

References (14)

1. Clasener HAL, Vollaard EJ Saene HKF. Long-term prophylaxis of infection by selective decontamination in leukopenia and in mechanical ventilation. Rev Infect Dis 9: 295-328, 1987.
2. Donelly JP. Selective decontamination of the digestive tract and its role in antimicrobial prophylaxis (review). J Antimicrob Chemother 31: 813-829, 1993.
3. Vollaard EJ, Clasener HAL. Colonization Resistence. Minireview. Antimicrob Agents Chemother 38: 409-414, 1994.
4. Vollaard EJ, Clasener HAL, Janssen AJHM, Wynne HJA. Influence of amoxicillin on microbial colonization resistance in healthy volunteers. A methodological study. J Antimicrob Chemother 25: 861-867, 1990.
5. Vollaard EJ, Clasener HAL, Janssen AJHM, Wynne HJA. Influence of cefotaxime on microbial colonization resistance in healthy volunteers. J Antimicrob Chemother 26: 117-123, 1990.
6. Vollaard EJ, Clasener HAL, Janssen AJHM. The contribution of cschirichia coli to microbial colonization resistance. J Antimicrob Chemother 26: 411-418, 1990.
7. Vollaard EJ, Clasener HAL, Janssen AJHM. Influence of pefloxacin on microbial colonization resistance in healthy volunteers. Eur J Clin Microbiol Infect Dis 11: 257-260, 1992.
8. Vollaard EJ, Clasener HAL, Janssen AJHM. Influence of cephadrinre on microbial colonization resistance in healthy volunteers. Microb Ecol Health Dis 5: 147-153, 1992.
9. Vollaard EJ, Clasener HAL, Janssen AJHM. Co-trimoxazole impairs colonization resistance in healthy volunteers. J Antimicrob Chemother 30: 685-691, 1992.
10. Campoli-Richards DM, Monk JP, Price A, Benfield P, Todd PA, Ward A. Ciprofloxacin. A review of its antibacterial activity, pharmacokinetic property and therapeutic use. Drugs 35: 373-447, 1988.
11. Edmund C, Nord CE. A review on the impact of 4-quinolones on the normal oropharyngeal and intestinal human microflora. Infection 16: 12/8-16/12, 1988.
12. Leur JJJPM van de, Volaard EJ, Janssen AJHM, Dofferhoff ASM. Faecal concentration of pefloxacin during infection prophlaxis in neutropenic patients. Antimicrob Agents and Chemotherapy 39: 1182-1184, 1995.
13. Leur JJJPM van de, Thunnissen PLM, Clasener HAL, Muller NF, Dofferhoff ASM. Influence of imipenem/cilastine, cefotaxime and cotrimoxazole on microbial colonization of the digestive tract. Scand J Infect Dis 25: 473-479, 1993.
14. Heimdahl A, Nord CE. Effect of phenoxymethylpenicillin and clindamycin on the oral, throat and faecal microflora of man. Scand J Infect Dis 11: 233-242, 1979.