SKDM human leukocyte antigen (HLA) tool: A comprehensive HLA and disease associations analysis software

Human Immunology

Volumn 69, Issue 8, 2008, Pages 522-525

  Kanterakis, Stathis ^a   Magira, Eleni ^a   Rosenman, Kenneth D ^b   Rossman, Milton ^c   Talsania, Keyur ^a   Monos, Dimitri S ^a  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Disease association; HLA; Immunogenetics; MHC; SKDM

Indexed keywords

AMINO ACID; EPITOPE; HLA A ANTIGEN; HLA ANTIGEN; HLA B ANTIGEN; HLA DPB1 ANTIGEN; HLA DQA1 ANTIGEN; HLA DQB1 ANTIGEN; HLA DR ANTIGEN;

ALLELE; AMINO ACID SEQUENCE; ARTICLE; CASE CONTROL STUDY; DATA ANALYSIS SOFTWARE; DISEASE ASSOCIATION; GENE INTERACTION; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; IMMUNOLOGICAL PROCEDURES; PRIORITY JOURNAL; ZYGOSITY;

ALLELES; GENETIC PREDISPOSITION TO DISEASE; HLA ANTIGENS; HUMANS; SOFTWARE;

EID: 50949089017     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2008.05.011     Document Type: Article

References (15)

1. Morel P.A., Dorman J.S., Todd J.A., McDevitt H.O., and Trucco M. Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: a family study. Proc Natl Acad Sci USA 85 (1988) 8111-8115
2. Todd J.A., Bell J.I., and McDevitt H.O. HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus. Nature 329 (1987) 599-604
3. Zerva L., Cizman B., Mehra N.K., Alahari S.K., Murali R., Zmijewski C.M., et al. Arginine at positions 13 or 70-71 in pocket 4 of HLA-DRB1 alleles is associated with susceptibility to tuberculoid leprosy. J Exp Med 183 (1996) 829-836
4. McVean G.A., Myers S.R., Hunt S., Deloukas P., Bentley D.R., and Donnelly P. The fine-scale structure of recombination rate variation in the human genome. Science 304 (2004) 581-584
5. Miretti M.M., Walsh E.C., Ke X., Delgado M., Griffiths M., Hunt S., et al. A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms. Am J Hum Genet 76 (2005) 634-646
6. Brown J.H., Jardetzky T.S., Gorga J.C., Stern L.J., Urban R.G., Strominger J.L., et al. Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature 364 (1993) 33-39
7. Stern L.J., Brown J.H., Jardetzky T.S., Gorga J.C., Urban R.G., Strominger J.L., et al. Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide. Nature 368 (1994) 215-221
8. Svejgaard A., and Ryder L.P. HLA and disease associations: detecting the strongest association. Tissue Antigens 43 (1994) 18-27
9. Nejentsev S., Howson J.M., Walker N.M., Szeszko J., Field S.F., Stevens H.E., et al. Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A. Nature 450 (2007) 887-892
10. Lancaster A., Nelson M.P., Meyer D., Thomson G., and Single R.M. PyPop: a software framework for population genomics: analyzing large-scale multi-locus genotype data. Pac Symp Biocomput 8 (2003) 514-525
11. Lancaster A.K., Single R.M., Solberg O.D., Nelson M.P., and Thomson G. PyPop update-a software pipeline for large-scale multilocus population genomics. Tissue Antigens 69 Suppl 1 (2007) 192-197
12. Haldane J.B. The estimation and significance of the logarithm of a ratio of frequencies. Ann Hum Genet 20 (1956) 309-311
13. Woolf B. On estimating the relation between blood group and disease. Ann Hum Genet 19 (1955) 251-253
14. Monos D.S., Pappas J., Magira E.E., Gaughan J., Sakkas L., Aplenc R., et al. Identification of HLA-DQα and -DRβ residues associated with susceptibility and protection to epithelial ovarian cancer. Hum Immunol 66 (2005) 554-562
15. Magira E.E., Papaioakim M., Nachamkin I., Griffin J.W., McKhann G.M., Monos D.S., et al. Differential distribution of HLA-DQβ/DRβ epitopes in the two forms of Guillain-Barré syndrome, acute motor axonal neuropathy and acute inflammatory demyelinating polyneuropathy (AIDP): identification of DQβ epitopes associated with susceptibility to and protection from AIDP. J Immunol 170 (2003) 3074-3080