Altered expression of sodium transporters and water channels in the submandibular gland of rats treated with nitric oxide synthesis inhibitors

Electrolyte and Blood Pressure

Volumn 6, Issue 1, 2008, Pages 9-14

  Seo, Il Young ^a   Kim, Miwon ^a   Lee, JongUn ^b   Ryu, Sun Youl ^a  

^a Chonnam National University   (South Korea)

^b Chonnam National University Medical School   (South Korea)

Author keywords

Aquaporins; Nitric oxide; Sodium transporters; Submandibular gland

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); AQUAPORIN; AQUAPORIN 1; AQUAPORIN 5; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PROTEIN SUBUNIT; SODIUM POTASSIUM CHLORIDE COTRANSPORTER; SODIUM PROTON EXCHANGE PROTEIN 1; TAP WATER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; REGULATORY MECHANISM; SALIVATION; SODIUM TRANSPORT; SPRAGUE DAWLEY RAT; SUBMANDIBULAR GLAND; WESTERN BLOTTING;

EID: 50849119415     PISSN: 17385997     EISSN: None     Source Type: Journal    
DOI: 10.5049/EBP.2008.6.1.9     Document Type: Article

References (22)

1. Robertson MA, Woodside M, Foskett JK, Orlowski J, Grinstein S: Muscarinic agonists induce phosphorylation-independent activation of the NHE-1 isoform of the Na+/H+ antiporter in salivary acinar cells. J Biol Chem 272:287-294, 1997
2. Peagler FD, Redman RS: Enzyme histochemical localization of Na(+),K(+)-ATPase and NADH-DE in the developing rat parotid gland. Anat Rec 256:72-77, 1999
3. Robertson MA, Foskett JK: Na+ transport pathways in secretory acinar cells: membrane cross talk mediated by [Cl-]i. Am J Physiol 267:046-156, 1994
4. Pirani D, Evans LA, Cook DI, Young JA: Intracellular pH in the rat mandibular salivary gland: the role of Na-H and Cl-HCO3 antiports in secretion. Pflugers Arch 408:178-184, 1987
5. Case RM, Hunter M, Novak I, Young JA: The anionic basis of fluid secretion by the rabbit mandibular salivary gland. J Physiol 349:619-630, 1984
6. Young JA, Cook DI, Evans LA, Pirani D: Effects of ion transport inhibition on rat mandibular gland secretion. J Dent Res 66:531-536, 1987
7. Awayda MS, Tousson A, Benos DJ: Regulation of a cloned epithelial Na+ channel by its beta- and gamma-subunits. Am J Physiol 273:C1889-1899, 1997
8. McNicholas CM, Canessa CM: Diversity of channels generated by different combinations of epithelial sodium channel subunits. J Gen Physiol 109:681-692, 1997
9. Nielsen S, King LS, Christensen BM, Agre P: Aquaporins in complex tissues. II. Subcellular distribution in respiratory and glandular tissues of rat. Am J Physiol 273:C1549-1561, 1997
10. Koyama Y, Yamamoto T, Tani T, Nihei Y, Kondo D, Funaki H, et al.: Expression and localization of aquaporins in rat gastrointestinal tract. Am J Physiol 276:C621-627, 1999
11. Delporte C, Steinfeld S: Distribution and roles of aquaporins in salivary glands. Biochim Biophys Acta 1758: 1061-1070, 2006
12. Tobin G, Edwards AV, Bloom SR, Ekstrom J: Nitric oxide in the control of submandibular gland function in the anaesthetized ferret. Exp Physiol 82:825-836, 1997
13. Lomniczi A, Suburo AM, Elverdin JC, Mastronardi CA, Diaz S, Rettori V, et al.: Rofe of nitric oxide in salivary secretion. Neuroimmunomodulation 5:226-233, 1998
14. Looms DK, Dissing S, Tritsaris K, Pedersen AM, Nauntofte B: Adrenoceptor-activated nitric oxide synthesis in salivary acinar cells. Adv Dent Res 14:62-68, 2000
15. Takai N, Uchihashi K, Higuchi K, Yoshida Y, Yamaguchi M: Localization of neuronal-constitutive nitric oxide synthase and secretory regulation by nitric oxide in the rat submandibular and sublingual glands. Arch Oral Biol 44: 745-750, 1999
16. Toba H, Nakagawa Y, Miki S, Shimizu T, Yoshimura A, Inoue R, et al.: Calcium channel blockades exhibit antiinflammatory and antioxidative effects by augmentation of endothelial nitric oxide synthase and the inhibition of angiotensin converting enzyme in the N(G)-nitro-Larginine methyl ester-induced hypertensive rat aorta: vasoprotective effects beyond the blood pressure-lowering effects of amlodipine and manidipine. Hypertens Res 28:689-700, 2005
17. De Gennaro Colonna V, Rigamonti A, Fioretti S, Bonomo S, Manfredi B, Ferrario P, et al.: Angiotensin-converting enzyme inhibition and angiotensin AT1-receptor antagonism equally improve endothelial vasodilator function in L-NAME-induced hypertensive rats. Eur J Pharmacol 516: 253-259, 2005
18. Ma T, Song Y, Gillespie A, Carlson EJ, Epstein CJ, Verkman AS: Defective secretion of saliva in transgenic mice lacking aquaporin-5 water channels. J Biol Chem 274: 20071-20074, 1999
19. Steinfeld S, Cogan E, King LS, Agre P, Kiss R, Delporte C: Abnormal distribution of aquaporin-5 water channel protein in salivary glands from Sjogren's syndrome patients. Lab Invest 81:143-148, 2001
20. King LS, Nielsen S, Agre P: Aquaporins in complex tissues. I. Developmental patterns in respiratory and glandular tissues of rat. Am J Physiol 273:C1541-1548, 1997
21. Akamatsu T, Parvin MN, Murdiastuti K, Kosugi-Tanaka C, Yao C, Miki O, et al.: Expression and localization of aquaporins, members of the water channel family, during development of the rat submandibular gland. Pflugers Arch 446:641-651, 2003
22. Verkman AS, Yang B, Song Y, Manley GT, Ma T: Role of water channels in fluid transport studied by phenotype analysis of aquaporin knockout mice. Exp Physiol 85 Spec No:S233-241, 2000