Functional organ preservation with definitive chemoradiotherapy for T4 laryngeal squamous cell carcinoma

Annals of Oncology

Volumn 19, Issue 9, 2008, Pages 1650-1654

  Knab, B R ^a   Salama, J K ^a   Solanki, A ^b   Stenson, K M ^a   Cohen, E E ^a   Witt, M E ^a   Haraf, D J ^a   Vokes, E E ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

Chemoradiotherapy; Head and neck cancer; Induction chemotherapy; Larynx therapy; Organ preservation; T4 laryngeal cancer

Indexed keywords

CARBOPLATIN; FLUOROURACIL; HYDROXYUREA; PACLITAXEL;

ADULT; ARTICLE; CANCER ADJUVANT THERAPY; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER SURGERY; CANCER SURVIVAL; CLINICAL ARTICLE; COMPLETE VOICE LOSS; CONTINUOUS INFUSION; CONTROLLED STUDY; DERMATITIS; DISEASE FREE SURVIVAL; FEMALE; FUNCTIONAL ASSESSMENT; HOARSENESS; HUMAN; LARYNGECTOMY; LARYNX CARCINOMA; MALE; MUCOSA INFLAMMATION; MULTIPLE CYCLE TREATMENT; NEUTROPENIA; ORGAN PRESERVATION; OVERALL SURVIVAL; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SPEECH DISORDER; SPEECH RATE; SQUAMOUS CELL CARCINOMA; TREATMENT DURATION; TREATMENT RESPONSE; TUMOR VOLUME;

EID: 50849115449     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdn173     Document Type: Article

References (22)

1. Jemal A, Tiwari RC, Murray T et al. Cancer statistics, 2004. CA Cancer J Clin 2004; 54: 8-29.
2. Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer. The Department of Veterans Affairs. Laryngeal Cancer Study Group. N Engl J Med 1991; 324: 1685-1690.
3. Forastiere AA, Goepfert H, Maor M et al. Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer. N Engl J Med 2003; 349: 2091-2098.
4. Pfister DG, Laurie SA, Weinstein GS et al. American Society of Clinical Oncology clinical practice guideline for the use of larynx-preservation strategies in the treatment of laryngeal cancer. J Clin Oncol 2006; 24: 3693-3704.
5. Hinerman RW, Mendenhall WM, Amdur RJ et al. Carcinoma of the supraglottic larynx: Treatment results with radiotherapy alone or with planned neck dissection. Head Neck 2002; 24: 456-467.
6. Kies MS, Haraf DJ, Rosen F et al. Concomitant infusional paclitaxel and fluorouracil, oral hydroxyurea, and hyperfractionated radiation for locally advanced squamous head and neck cancer. J Clin Oncol 2001; 19: 1961-1969.
7. Rosen FR, Haraf DJ, Kies MS et al. Multicenter randomized phase II study of paclitaxel (1-hour infusion), fluorouracil, hydroxyurea, and concomitant twice daily radiation with or without erythropoietin for advanced head and neck cancer. Clin Cancer Res 2003; 9: 1689-1697.
8. Vokes EE, Stenson KM, Kistner E et al. Sequential evaluation of reduced radiotherapy doses in a phase II trial of induction chemotherapy (IndCT) followed by concomitant chemoradiotherapy (CTX) for advanced head and neck cancer (HNC). J Clin Oncol 2006; 24:287s 5528.
9. Adelstein DJ, Lavertu P, Saxton JP et al. Mature results of a phase III randomized trial comparing concurrent chemoradiotherapy with radiation therapy alone in patients with stage III and IV squamous cell carcinoma of the head and neck. Cancer 2000; 88: 876-883.
10. Adelstein DJ, Li Y, Adams GL et al. Art intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer. J Clin Oncol 2003; 21: 92-98.
11. Al-Sarraf M, LeBlanc M, Giri PG et al. Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer: Phase III randomized intergroup study 0099. J Clin Oncol 1998; 16: 1310-1317.
12. Bernier J, Domenge C, Ozsahin M et al. Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer. N Engl J Med 2004; 350: 1945-1952.
13. Brizel DM, Albers ME, Fisher SR et al. Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer. N Engl J Med 1998; 338: 1798-1804.
14. Calais G, Alfonsi M, Bardet E et al. Stage III and IV cancers of the oropharynx: Results of a randomized study of Gortec comparing radiotherapy alone with concomitant chemotherapy. Bull Cancer 2000; 87: 48-53.
15. Cooper JS, Pajak TF, Forastiere AA et al. Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck. N Engl J Med 2004; 350: 1937-1944.
16. Forastiere M, Weber RS, Pajak T et al. Long-term results of Intergroup RTOG 91-11: A phase III trial to preserve the larynx-induction cisplatin/ 5-FU and radiation therapy versus concurrent cisplatin and radiation therapy versus radiation therapy. J Clin Oncol 2006; 24: 248s (Abstr 5517).
17. Mendenhall WM. T3-4 squamous cell carcinoma of the larynx treated with radiation therapy alone. Semin Radiat Oncol 1998; 8: 262-269.
18. Brockstein B. Organ preservation for advanced head and neck cancer concomitant chemoradiation. Cancer Treat Res 2003; 114: 235-248.
19. Brockstein B, Haraf DJ, Rademaker AW et al. Patterns of failure, prognostic factors and survival in locoregionally advanced head and neck cancer treated with concomitant chemoradiotherapy: A 9-year, 337-patient, multi-institutional experience. Ann Oncol 2004; 15: 1179-1186.
20. Haraf D, Rosen F, Stenson K et al. Induction chemotherapy followed by concomitant TFHX chemoradiotherapy with reduced dose radiation in advanced head and neck cancer. Clin Cancer Res 2003; 9: 5936-5943.
21. Eisbruch A, Thornton AF, Urba S et al. Chemotherapy followed by accelerated fractionated radiation for larynx preservation in patients with advanced laryngeal cancer. J Clin Oncol 1996; 14: 2322-2330.
22. Urba S, Wolf G, Eisbruch A et al. Single-cycle induction chemotherapy selects patients with advanced laryngeal cancer for combined chemoradiation: A new treatment paradigm. J Clin Oncol 2006; 24: 593-598.