Multiplex MassTag-PCR for respiratory pathogens in pediatric nasopharyngeal washes negative by conventional diagnostic testing shows a high prevalence of viruses belonging to a newly recognized rhinovirus clade

Journal of Clinical Virology

Volumn 43, Issue 2, 2008, Pages 219-222

  Dominguez, Samuel R ^a   Briese, Thomas ^b   Palacios, Gustavo ^b   Hui, Jeffrey ^b   Villari, Joseph ^b   Kapoor, Vishal ^b   Tokarz, Rafal ^b   Glodé, Mary P ^a   Anderson, Marsha S ^a   Robinson, Christine C ^c   Holmes, Kathryn V ^a   Lipkin, W Ian ^b  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b Columbia University ^*  (United States)

^c CHILDREN S HOSPITAL COLORADO   (United States)

Author keywords

Acute respiratory illness; HRV C; MassTag PCR; Pediatrics; Rhinovirus

Indexed keywords

ANTIBIOTIC AGENT; SALBUTAMOL; STEROID;

ADENOVIRUS; ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; COMORBIDITY; CONTROLLED STUDY; ENTEROVIRUS; FEMALE; HUMAN; HUMAN METAPNEUMOVIRUS; HUMAN RHINOVIRUS; IMMUNOFLUORESCENCE; INFANT; INFLUENZA VIRUS A; INFLUENZA VIRUS B; MALE; NUCLEOTIDE SEQUENCE; PARAINFLUENZA VIRUS 1; PARAINFLUENZA VIRUS 2; PARAINFLUENZA VIRUS 3; PATHOGENESIS; PICORNAVIRUS; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PREVALENCE; PRIORITY JOURNAL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RESPIRATORY TRACT INFECTION; TREATMENT OUTCOME; VIRUS DETECTION; VIRUS INFECTION;

ACUTE DISEASE; CHILD, PRESCHOOL; ENTEROVIRUS; ENTEROVIRUS INFECTIONS; FEMALE; HUMANS; INFANT; MALE; NASOPHARYNX; PICORNAVIRIDAE INFECTIONS; POLYMERASE CHAIN REACTION; PREVALENCE; RESPIRATORY TRACT INFECTIONS; RHINOVIRUS; VIRUS DISEASES;

EID: 50849086724     PISSN: 13866532     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcv.2008.06.007     Document Type: Article

References (24)

1. WHO, 2003. The World Health Report 2003: shaping the future. World Health Organization.
2. Klig J.E., and Shah N.B. Office pediatrics: current issues in lower respiratory infections in children. Curr Opin Pediatr 17 (2005) 111-118
3. Klig J.E. Current challenges in lower respiratory infections in children. Curr Opin Pediatr 16 (2004) 107-112
4. Fendrick A.M., Monto A.S., Nightengale B., and Sarnes M. The economic burden of non-influenza-related viral respiratory tract infection in the United States. Arch Intern Med 163 (2003) 487-494
5. Griffin M.R., Walker F.J., Iwane M.K., Weinberg G.A., Staat M.A., and Erdman D.D. Epidemiology of respiratory infections in young children: insights from the new vaccine surveillance network. Pediatr Infect Dis J 23 (2004) S188-S192
6. Briese T., Palacios G., Kokoris M., Jabado O., Liu Z., Renwick N., et al. Diagnostic system for rapid and sensitive differential detection of pathogens. Emerg Infect Dis 11 (2005) 310-313
7. Lamson D., Renwick N., Kapoor V., Liu Z., Palacios G., Ju J., et al. MassTag polymerase-chain-reaction detection of respiratory pathogens, including a new rhinovirus genotype, that caused influenza-like illness in New York State during 2004-2005. J Infect Dis 194 (2006) 1398-1402
8. Palacios G., Briese T., Kapoor V., Jabado O., Liu Z., Venter M., et al. MassTag polymerase chain reaction for differential diagnosis of viral hemorrhagic fever. Emerg Infect Dis 12 (2006) 692-695
9. Dominguez S.R., Anderson M.S., Glode M.P., Robinson C.C., and Holmes K.V. Blinded case-control study of the relationship between human coronavirus NL63 and Kawasaki syndrome. J Infect Dis 194 (2006) 1697-1701
10. Lu X., Chittaganpitch M., Olsen S.J., Mackay I.M., Sloots T.P., Fry A.M., et al. Real-time PCR assays for detection of bocavirus in human specimens. J Clin Microbiol 44 (2006) 3231-3235
11. Coiras M.T., Aguilar J.C., Garcia M.L., Casas I., and Perez-Brena P. Simultaneous detection of fourteen respiratory viruses in clinical specimens by two multiplex reverse transcription nested-PCR assays. J Med Virol 72 (2004) 484-495
12. McErlean P., Shackelton L.A., Lambert S.B., Nissen M.D., Sloots T.P., and Mackay I.M. Characterisation of a newly identified human rhinovirus, HRV-QPM, discovered in infants with bronchiolitis. J Clin Virol 39 (2007) 67-75
13. Lau S.K., Yip C.C., Tsoi H.W., Lee R.A., So L.Y., Lau Y.L., et al. Clinical features and complete genome characterization of a distinct human rhinovirus (HRV) genetic cluster, probably representing a previously undetected HRV species, HRV-C, associated with acute respiratory illness in children. J Clin Microbiol 45 (2007) 3655-3664
14. Renwick N., Schweiger B., Kapoor V., Liu Z., Villari J., Bullmann R., et al. A recently identified rhinovirus genotype is associated with severe respiratory-tract infection in children in Germany. J Infect Dis 196 (2007) 1754-1760
15. Kistler A., Avila P.C., Rouskin S., Wang D., Ward T., Yagi S., et al. Pan-viral screening of respiratory tract infections in adults with and without asthma reveals unexpected human coronavirus and human rhinovirus diversity. J Infect Dis 196 (2007) 817-825
16. Arruda E., Pitkaranta A., Witek Jr. T.J., Doyle C.A., and Hayden F.G. Frequency and natural history of rhinovirus infections in adults during autumn. J. Clin. Microbiol. 35 (1997) 2864-2868
17. Makela M.J., Puhakka T., Ruuskanen O., Leinonen M., Saikku P., Kimpimaki M., et al. Viruses and bacteria in the etiology of the common cold. J Clin Microbiol 36 (1998) 539-542
18. Rakes G.P., Arruda E., Ingram J.M., Hoover G.E., Zambrano J.C., Hayden F.G., et al. Rhinovirus and respiratory syncytial virus in wheezing children requiring emergency care. IgE and eosinophil analyses. Am J Respir Crit Care Med 159 (1999) 785-790
19. El-Sahly H.M., Atmar R.L., Glezen W.P., and Greenberg S.B. Spectrum of clinical illness in hospitalized patients with "common cold" virus infections. Clin Infect Dis 31 (2000) 96-100
20. Miller E.K., Lu X., Erdman D.D., Poehling K.A., Zhu Y., Griffin M.R., et al. Rhinovirus-associated hospitalizations in young children. J Infect Dis 195 (2007) 773-781
21. Manoha C., Espinosa S., Aho S.L., Huet F., and Pothier P. Epidemiological and clinical features of hMPV, RSV and RVs infections in young children. J Clin Virol 38 (2007) 221-226
22. Juven T., Mertsola J., Waris M., Leinonen M., Meurman O., Roivainen M., et al. Etiology of community-acquired pneumonia in 254 hospitalized children. Pediatr Infect Dis J 19 (2000) 293-298
23. Michelow I.C., Olsen K., Lozano J., Rollins N.K., Duffy L.B., Ziegler T., et al. Epidemiology and clinical characteristics of community-acquired pneumonia in hospitalized children. Pediatrics 113 (2004) 701-707
24. Kusel M.M., de Klerk N.H., Holt P.G., Kebadze T., Johnston S.L., and Sly P.D. Role of respiratory viruses in acute upper and lower respiratory tract illness in the first year of life: a birth cohort study. Pediatr Infect Dis J 25 (2006) 680-686