Quantitative multi-agent models for simulating protein release from PLGA bioerodible nano- and microspheres

Journal of Pharmaceutical and Biomedical Analysis

Volumn 48, Issue 2, 2008, Pages 361-368

  Barat, Ana ^a   Crane, Martin ^a   Ruskin, Heather J ^a  

^a School of Computing   (Ireland)

Author keywords

Cellular Automata; Dissolution; Drug delivery; Microspheres; Modelling; Monte Carlo; Multi agents; Nanospheres; PLGA; Simulation

Indexed keywords

MICROSPHERE; NANOSPHERE; POLYGLACTIN;

ARTICLE; DISSOLUTION; DRUG DELIVERY SYSTEM; ENCAPSULATION; MACROMOLECULE; MODEL; MONTE CARLO METHOD; POROSITY; PRIORITY JOURNAL; PROTEIN SECRETION; QUANTITATIVE ANALYSIS; SIMULATION;

LACTIC ACID; MICROSPHERES; MODELS, THEORETICAL; NANOPARTICLES; POLYGLYCOLIC ACID; POROSITY; PROTEINS; SOLUBILITY;

EID: 50649118323     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2008.02.031     Document Type: Article

References (24)

1. Ungaro F., Biondi M., Indolfi L., Rosa G.D., Rotonda M.I.L., Quaglia F., and Netti P.V. Biomaterials (2004)
2. Merkle H., Gander B., Meinel L., and Walter E. Business Briefing Pharmatech. (2002) 1-6
3. D. Charlton, M. Peterson, K. Spiller, A. Lowman, P. Torzilli, S.A. Maher, Private Communication, 2006
4. Göpferich A. Am. Inst. Chem. Eng. (AIChE) J. 41 10 (1995) 2292-2299
5. Feng S., and Chien S. Chem. Eng. Sci. 58 (2003) 4087-4114
6. ul-Ain Q., Sharma S., and Khuller G.K. Antimicrob. Agents Chemother. 47 9 (2003) 3005-3007
7. Illum L., Church A., Butterworth M., Arien A., Whetstone J., and Davis S. Pharm. Res. 18 5 (2001) 640-645
8. Kilic A.C., Capan Y., Vural I., Gursoy R.N., Dalkara T., Cuine A., and Hincal A.A. J. Microencapsulation 22 6 (2005) 633-641
9. Sandor M., Enscore D., Weston P., and Mathiowitz E. J. Controlled Release 76 (2001) 297-311
10. Lam X., Duenas E., Daugherty A., Levin N., and Cleland J. J. Controlled Release 67 (2000) 281-292
11. Siepmann J., and Göpferich A. Adv. Drug Deliv. Rev. 48 (2001) 229-247
12. Siepmann J., Faisant N., and Benoit J.-P. Pharm. Res. 19 12 (2002) 1885-1893
13. Batycky R.P., Hanes J., Langer R., and Edwards D.A. J. Pharm. Sci. 12 (1997) 1464-1477
14. Zhang M., Yang Z., Chow L.-L., and Wang C.-H. J. Pharm. Sci. 92 10 (2003) 2040-2056
15. Göpferich A. Biomaterials 17 (1996) 103-114
16. Göpferich A. Biomaterials 18 (1997) 397-403
17. Göpferich A. J. Controlled Release 44 (1997) 271-281
18. Zygourakis K., and Markenscoff P.A. Biomaterials 17 (1996) 125-135
19. Zhao A., and Rodgers V. J. Controlled Release 113 12 (2006) 15-22
20. Kisler J.M., Stevens G.W., and O'Connor A. J. Mater. Phys. Mech. 4 (2001) 89-93
21. Kosmidis K., Rinaki E., Argyrakis P., and Macheras P. Int. J. Pharm. 254 2 (2003) 183-188
22. Nicholson C., and Sychova E. Trends Neurosci. 21 5 (1998) 207-215
23. A. Barat, H.J. Ruskin, M. Crane, Theory Biosci. (special issue), in press.
24. Goodhill J. Eur. J. Neurosci. 9 (1997) 1414-1421