Host responses in the bursa of Fabricius of chickens infected with virulent Marek's disease virus

Virology

Volumn 379, Issue 2, 2008, Pages 256-265

  Abdul Careem, M F ^a   Hunter, B D ^a   Lee, L F ^b   Fairbrother, J H ^c   Haghighi, H R ^a   Read, L ^a   Parvizi, P ^a   Heidari, M ^b   Sharif, S ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b U S DEPARTMENT OF AGRICULTURE   (United States)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Bursa of Fabricius; Cytokine; Macrophages; Marek's disease virus; Real time PCR; T cells

Indexed keywords

ALPHA INTERFERON; GAMMA INTERFERON; GLYCOPROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 8; PHOSPHOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIRD DISEASE; BURSA FABRICII; CELL INFILTRATION; CONTROLLED STUDY; GENE CONTROL; GENE EXPRESSION; GENOME; MACROPHAGE; MARDIVIRUS; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; VIRUS GENE;

ANIMALS; ANIMALS, NEWBORN; ANTIGENS, VIRAL; BASE SEQUENCE; BURSA OF FABRICIUS; CHICKENS; CYTOKINES; DNA PRIMERS; GENE EXPRESSION; HOST-PATHOGEN INTERACTIONS; MACROPHAGES; MARDIVIRUS; MAREK DISEASE; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHOPROTEINS; RNA, MESSENGER; T-LYMPHOCYTE SUBSETS; VIRULENCE; VIRUS REPLICATION;

GALLID HERPESVIRUS 2; GALLUS GALLUS;

EID: 50649107251     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2008.06.027     Document Type: Article

References (71)

1. Abdul-Careem M.F., Hunter B.D., Nagy E., Read L.R., Sanei B., Spencer J.L., and Sharif S. Development of a real-time PCR assay using SYBR green chemistry for monitoring Marek's disease virus genome load in feather tips. J. Virol. Methods 133 (2006) 34-40
2. Abdul-Careem M.F., Hunter B.D., Parvizi P., Haghighi H.R., Thanthrige-Don N., and Sharif S. Cytokine gene expression patterns associated with immunization against Marek's disease in chickens. Vaccine 25 (2007) 424-432
3. Abdul-Careem M.F., Hunter B.D., Sarson A.J., Mayameei A., Zhou H., and Sharif S. Marek's disease virus-induced transient paralysis is associated with cytokine gene expression in the nervous system. Viral Immunol. 19 (2006) 167-176
4. Abdul-Careem M.F., Hunter B.D., Sarson A.J., Parvizi P., Haghighi H.R., Read L., Heidari M., and Sharif S. Host responses are induced in feathers of chickens infected with Marek's disease virus. Virology 370 (2008) 323-332
5. Babcock G.J., Decker L.L., Freeman R.B., and Thorley-Lawson D.A. Epstein-barr virus-infected resting memory B cells, not proliferating lymphoblasts, accumulate in the peripheral blood of immunosuppressed patients. J Exp Med. 190 (1999) 567-576
6. Baigent S.J., Ross L.J., and Davison T.F. Differential susceptibility to Marek's disease is associated with differences in number, but not phenotype or location, of pp38+ lymphocytes. J. Gen. Virol. 79 (1998) 2795-2802
7. Barrow A.D., Burgess S.C., Baigent S.J., Howes K., and Nair V.K. Infection of macrophages by a lymphotropic herpesvirus: a new tropism for Marek's disease virus. J. Gen. Virol. 84 (2003) 2635-2645
8. Beasley J.N., Patterson L.T., and McWade D.H. Transmission of Marek's disease by poultry house dust and chicken dander. Am. J. Vet. Res. 31 (1970) 339-344
9. Brisbin J.T., Zhou H., Gong J., Sabour P., Akbari M.R., Haghighi H.R., Yu H., Clarke A., Sarson A.J., and Sharif S. Gene expression profiling of chicken lymphoid cells after treatment with Lactobacillus acidophilus cellular components. Dev. Comp. Immunol. 32 (2007) 563-574
10. Burgess S.C., Basaran B.H., and Davison T.F. Resistance to Marek's disease herpesvirus-induced lymphoma is multiphasic and dependent on host genotype. Vet. Pathol. 38 (2001) 129-142
11. Burgess S.C., and Davison T.F. Identification of the neoplastically transformed cells in Marek's disease herpesvirus-induced lymphomas: recognition by the monoclonal antibody AV37. J. Virol. 76 (2002) 7276-7292
12. Buscaglia C., Calnek B.W., and Schat K.A. Effect of immunocompetence on the establishment and maintenance of latency with Marek's disease herpesvirus. J.Gen.Virol. 69 (1988) 1067-1077
13. Calnek B.W. Pathogenesis of Marek's disease virus infection. Curr. Top. Microbiol. Immunol. 255 (2001) 25-55
14. Calnek B.W., Adldinger H.K., and Kahn D.E. Feather follicle epithelium: a source of enveloped and infectious cell-free herpesvirus from Marek's disease. Avian Dis. 14 (1970) 219-233
15. Calnek B.W., Harris R.W., Buscaglia C., Schat K.A., and Lucio B. Relationship between the immunosuppressive potential and the pathotype of Marek's disease virus isolates. Avian Dis. 42 (1998) 124-132
16. Calnek B.W., Schat K.A., Ross L.J., Shek W.R., and Chen C.L. Further characterization of Marek's disease virus-infected lymphocytes. I. in vivo infection. Int. J. Cancer 33 (1984) 389-398
17. Cooper M.D., Raymond D.A., Peterson R.D., South M.A., and Good R.A. The functions of the thymus system and the bursa system in the chicken. J. Exp. Med. 123 (1966) 75-102
18. Cortes A., Fonfria J., Vicente A., Varas A., Moreno J., and Zapata A.G. T-dependent areas in the chicken bursa of Fabricius: an immunohistological study. Anat.Rec. 242 (1995) 91-95
19. Cui X., Lee L.F., Reed W.M., Kung H.J., and Reddy S.M. Marek's disease virus-encoded vIL-8 gene is involved in early cytolytic infection but dispensable for establishment of latency. J. Virol. 78 (2004) 4753-4760
20. Davison, A.J., Eberle, R., Hayward, G.S., McGeoch, D.J., Minson, A.C., Pellett, P.E., Roizman,B., Studdert, M.J., Thiry, E., 2002. Virus taxonomy, http://www.ncbi.nlm.nih.gov/ICTVdb/Ictv/rf_herpe.htm.
21. Djeraba A., Bernardet N., Dambrine G., and Quere P. Nitric oxide inhibits Marek's disease virus replication but is not the single decisive factor in interferon-gamma-mediated viral inhibition. Virology 277 (2000) 58-65
22. Ekino S., Suginohara K., Urano T., Fujii H., Matsuno K., and Kotani M. The bursa of Fabricius: a trapping site for environmental antigens. Immunology 55 (1985) 405-410
23. Eldaghayes I., Rothwell L., Williams A., Withers D., Balu S., Davison F., and Kaiser P. Infectious bursal disease virus: strains that differ in virulence differentially modulate the innate immune response to infection in the chicken bursa. Viral Immunol. 19 (2006) 83-91
24. Frucht D.M., Fukao T., Bogdan C., Schindler H., O'Shea J.J., and Koyasu S. IFN-gamma production by antigen-presenting cells: mechanisms emerge. Trends Immunol. 22 (2001) 556-560
25. Garcia-Camacho L., Schat K.A., Brooks Jr. R., and Bounous D.I. Early cell-mediated immune responses to Marek's disease virus in two chicken lines with defined major histocompatibility complex antigens. Vet. Immunol. Immunopathol. 95 (2003) 145-153
26. Gimeno I.M., Witter R.L., Hunt H.D., Lee L.F., Reddy S.M., and Neumann U. Marek's disease virus infection in the brain: virus replication, cellular infiltration, and major histocompatibility complex antigen expression. Vet. Pathol. 38 (2001) 491-503
27. Gimeno I.M., Witter R.L., Hunt H.D., Reddy S.M., Lee L.F., and Silva R.F. The pp38 gene of Marek's disease virus (MDV) is necessary for cytolytic infection of B cells and maintenance of the transformed state but not for cytolytic infection of the feather follicle epithelium and horizontal spread of MDV. J. Virol. 79 (2005) 4545-4549
28. Göbel T.W., Schneider K., Schaerer B., Meiri I., Puehler F., Weigend S., Staeheli P., and Kaspers B. IL-18 stimulates the proliferation and IFN-gamma release of CD4+ T cells in the chicken: conservation of a Th1-like system in a nonmammalian species. J. Immunol 171 (2003) 1809-1815
29. Guidotti L.G., and Chisari F.V. Noncytolytic control of viral infections by the innate and adaptive immune response. Annu. Rev. Immunol. 19 (2001) 65-91
30. Heidari M., Huebner M., Kireev D., and Silva R.F. Transcriptional profiling of Marek's disease virus genes during cytolytic and latent infection. Virus Genes 36 (2008) 383-392
31. Hunt H.D., Lupiani B., Miller M.M., Gimeno I., Lee L.F., and Parcells M.S. Marek's disease virus down-regulates surface expression of MHC (B complex) class I (BF) glycoproteins during active but not latent infection of chicken cells. Virology 282 (2001) 198-205
32. Islam A.F., Wong C.W., Walkden-Brown S.W., Colditz I.G., Arzey K.E., and Groves P.J. Immunosuppressive effects of Marek's disease virus (MDV) and herpesvirus of turkeys (HVT) in broiler chickens and the protective effect of HVT vaccination against MDV challenge. Avian Pathol. 31 (2002) 449-461
33. Jarosinski K.W., Njaa B.L., O'connell P.H., and Schat K.A. Pro-Inflammatory responses in chicken spleen and brain tissues after infection with very virulent plus Marek's disease virus. Viral Immunol. 18 (2005) 148-161
34. Kaiser P., Underwood G., and Davison F. Differential cytokine responses following Marek's disease virus infection of chickens differing in resistance to Marek's disease. J. Virol. 77 (2003) 762-768
35. Khatri M., Palmquist J.M., Cha R.M., and Sharma J.M. Infection and activation of bursal macrophages by virulent infectious bursal disease virus. Virus Res. 113 (2005) 44-50
36. Kim I.J., Gagic M., and Sharma J.M. Recovery of antibody-producing ability and lymphocyte repopulation of bursal follicles in chickens exposed to infectious bursal disease virus. Avian Dis. 43 (1999) 401-413
37. Kim I.J., You S.K., Kim H., Yeh H.Y., and Sharma J.M. Characteristics of bursal T lymphocytes induced by infectious bursal disease virus. J.Virol. 74 (2000) 8884-8892
38. Kodama H., Mikami T., Inoue M., and Izawa H. Inhibitory effects of macrophages against Marek's disease virus plaque formation in chicken kidney cell cultures. J. Natl. Cancer Inst. 63 (1979) 1267-1271
39. Kung H.J., Xia L., Brunovskis P., Li D., Liu J.L., and Lee L.F. Current topics in microbiology and immunology. In: Hirai K. (Ed). Meq: An MDV-specific bZIP transactivator with transforming properties (2001), Springer Verlag, Berlin 245-260
40. Lee L.F. Macrophage restriction of Marek's disease virus replication and lymphoma cell proliferation. J.Immunol. 123 (1979) 1088-1091
41. Levy A.M., Burgess S.C., Davidson I., Underwood G., Leitner G., and Heller E.D. Interferon-containing supernatants increase Marek's disease herpesvirus genomes and gene transcription levels, but not virion replication in vitro. Viral Immunol. 16 (2003) 501-509
42. Levy A.M., Heller E.D., Leitner G., and Davidson I. Effect of native chicken interferon on MDV replication. Acta Virol. 43 (1999) 121-127
43. Liu J.L., Lin S.F., Xia L., Brunovskis P., Li D., Davidson I., Lee L.F., and Kung H.J. MEQ and V-IL8: cellular genes in disguise?. Acta Virol. 43 (1999) 94-101
44. Malnati M.S., Marti M., LaVaute T., Jaraquemada D., Biddison W., DeMars R., and Long E.O. Processing pathways for presentation of cytosolic antigen to MHC class II-restricted T cells. Nature 357 (1992) 702-704
45. Morimura T., Cho K.-., Kudo Y., Hiramoto Y., Ohashi K., Hattori M., Sugimoto C., and Onuma M. Anti-viral and anti-tumor effects induced by an attenuated Marek's disease virus in CD4- or CD8-deficient chickens. Arch. Virol. 144 (1999) 1809-1818
46. Mossman K.L., and Ashkar A.A. Herpesviruses and the innate immune response. Viral Immunol. 18 (2005) 267-281
47. Ngai P., McCormick S., Small C., Zhang X., Zganiacz A., Aoki N., and Xing Z. Gamma interferon responses of CD4 and CD8 T-cell subsets are quantitatively different and independent of each other during pulmonary mycobacterium bovis BCG infection. Infect. Immun. 75 (2007) 2244-2252
48. Niikura M., Kim T., Hunt H.D., Burnside J., Morgan R.W., Dodgson J.B., and Cheng H.H. Marek's disease virus up-regulates major histocompatibility complex class II cell surface expression in infected cells. Virology 359 (2007) 212-219
49. Olah I., and Glick B. Follicle-associated epithelium and medullary epithelial tissue of the bursa of Fabricius are two different compartments. Anat. Rec. 233 (1992) 577-587
50. Palmquist J.M., Khatri M., Cha R.M., Goddeeris B.M., Walcheck B., and Sharma J.M. In vivo activation of chicken macrophages by infectious bursal disease virus. Viral Immunol. 19 (2006) 305-315
51. Parcells M.S., Lin S.F., Dienglewicz R.L., Majerciak V., Robinson D.R., Chen H.C., Wu Z., Dubyak G.R., Brunovskis P., Hunt H.D., Lee L.F., and Kung H.J. Marek's disease virus (MDV) encodes an interleukin-8 homolog (vIL-8): characterization of the vIL-8 protein and a vIL-8 deletion mutant MDV. J. Virol. 75 (2001) 5159-5173
52. Payne L.N. Pathological responses to infection. In: Davison F., and Nair V. (Eds). Marek's disease, an evolving problem (2004), Elsevier Academic Press, Great Britain 78-97
53. Powell P.C., Hartley K.J., Mustill B.M., and Rennie M. Studies on the role of macrophages in Marek's disease of the chicken. J. Reticuloendothel. Soc. 34 (1983) 289-297
54. Quere P., Rivas C., Ester K., Novak R., and Ragland W.L. Abundance of IFN-alpha and IFN-gamma mRNA in blood of resistant and susceptible chickens infected with Marek's disease virus (MDV) or vaccinated with turkey herpesvirus; and MDV inhibition of subsequent induction of IFN gene transcription. Arch. Virol. 150 (2005) 507-519
55. Qureshi M.A., Heggen C.L., and Hussain I. Avian macrophage: effector functions in health and disease. Dev. Comp. Immunol. 24 (2000) 103-119
56. Rautenschlein S., von Samson-Himmelstjerna G., and Haase C. A comparison of immune responses to infection with virulent infectious bursal disease virus (IBDV) between specific-pathogen-free chickens infected at 12 and 28 days of age. Vet. Immunol. Immunopathol. 115 (2007) 251-260
57. Rautenschlein S., Yeh H.Y., Njenga M.K., and Sharma J.M. Role of intrabursal T cells in infectious bursal disease virus (IBDV) infection: T cells promote viral clearance but delay follicular recovery. Arch. Virol. 147 (2002) 285-304
58. Rautenschlein S., Yeh H.Y., and Sharma J.M. The role of T cells in protection by an inactivated infectious bursal disease virus vaccine. Vet. Immunol. Immunopathol. 89 (2002) 159-167
59. Rautenschlein S., Yeh H.Y., and Sharma J.M. Comparative immunopathogenesis of mild, intermediate, and virulent strains of classic infectious bursal disease virus. Avian Dis. 47 (2003) 66-78
60. Reddy S.M., Lupiani B., Gimeno I.M., Silva R.F., Lee L.F., and Witter R.L. Rescue of a pathogenic Marek's disease virus with overlapping cosmid DNAs: use of a pp38 mutant to validate the technology for the study of gene function. Proc. Natl.Acad. Sci. U.S.A. 99 (2002) 7054-7059
61. Ross N., O'Sullivan G., Rothwell C., Smith G., Burgess S.C., Rennie M., Lee L.F., and Davison T.F. Marek's disease virus EcoRI-Q gene (meq) and a small RNA antisense to ICP4 are abundantly expressed in CD4+ cells and cells carrying a novel lymphoid marker, AV37, in Marek's disease lymphomas. J. Gen. Virol. 78 (1997) 2191-2198
62. Sarson A.J., Abdul-Careem M.F., Zhou H., and Sharif S. Transcriptional analysis of host responses to Marek's disease viral infection. Viral Immunol. 19 (2006) 747-758
63. Schat K.A., Calnek B.W., and Fabricant J. Influence of the bursa of Fabricius on the pathogenesis of Marek's disease. Infect. Immun. 31 (1981) 199-207
64. Schat K.A., Calnek B.W., and Fabricant J. Characterization of two highly oncogenic strains of Marek's disease virus. Avian Pathol. 11 (1982) 593-605
65. Schat K.A., and Xing Z. Specific and nonspecific immune responses to Marek's disease virus. Dev. Comp. Immunol. 24 (2000) 201-221
66. Shek W.R., Calnek B.W., Schat K.A., and Chen C.H. Characterization of Marek's disease virus-infected lymphocytes: discrimination between cytolytically and latently infected cells. J. Natl. Cancer Inst. 70 (1983) 485-491
67. Tanimura N., and Sharma J.M. Appearance of T cells in the bursa of Fabricius and cecal tonsils during the acute phase of infectious bursal disease virus infection in chickens. Avian Dis. 41 (1997) 638-645
68. Volpini L.M., Calnek B.W., Sneath B., Sekellick M.J., and Marcus P.I. Interferon modulation of Marek's disease virus genome expression in chicken cell lines. Avian Dis. 40 (1996) 78-87
69. Withers D.R., Young J.R., and Davison T.F. Infectious bursal disease virus-induced immunosuppression in the chick is associated with the presence of undifferentiated follicles in the recovering bursa. Viral Immunol. 18 (2005) 127-137
70. Xing Z., and Schat K.A. Expression of cytokine genes in Marek's disease virus-infected chickens and chicken embryo fibroblast cultures. Immunology 100 (2000) 70-76
71. Xing Z., and Schat K.A. Inhibitory effects of nitric oxide and gamma interferon on in vitro and in vivo replication of Marek's disease virus. J. Virol. 74 (2000) 3605-3612