-
1
-
-
53849090444
-
-
Ed, C.-H. Wong, Wiley-VCH, Weinheim, chap. 26.3;
-
a) Carbohydrate Based Drug Discovery, (Ed.: C.-H. Wong), Wiley-VCH, Weinheim, 2003, chap. 26.3;
-
(2003)
Carbohydrate Based Drug Discovery
-
-
-
3
-
-
53849112090
-
-
Ed, C.-H. Wong, Wiley-VCH, Weinheim, chap. 24;
-
c) Carbohydrate Based Drug Discovery, (Ed.: C.-H. Wong), Wiley-VCH, Weinheim, 2003, chap. 24;
-
(2003)
Carbohydrate Based Drug Discovery
-
-
-
6
-
-
0036802905
-
-
f) A. Vasella, G. J. Davies, M. Böhm, Curr. Opin. Chem. Biol. 2002, 6, 619;
-
(2002)
Curr. Opin. Chem. Biol
, vol.6
, pp. 619
-
-
Vasella, A.1
Davies, G.J.2
Böhm, M.3
-
9
-
-
1542763243
-
-
h) G. C. Look, C. H. Fotsh, C.-H. Wong, Acc. Chem. Res. 1993, 26, 182;
-
(1993)
Acc. Chem. Res
, vol.26
, pp. 182
-
-
Look, G.C.1
Fotsh, C.H.2
Wong, C.-H.3
-
11
-
-
0028338631
-
-
and references cited therein; For selected references, see: a
-
For selected references, see: a) E. W. Baxter, A. B. Reitz, J. Org. Chem. 1994, 59, 3175, and references cited therein;
-
(1994)
J. Org. Chem
, vol.59
, pp. 3175
-
-
Baxter, E.W.1
Reitz, A.B.2
-
12
-
-
0029887516
-
-
and references cited therein
-
b) A. I. Meyers, C. J. Andres, J. E. Resek, M. A. McLaughlin, C. C. Woodall, P. H. Lee, J. Org. Chem. 1996, 61, 2586, and references cited therein.
-
(1996)
J. Org. Chem
, vol.61
, pp. 2586
-
-
Meyers, A.I.1
Andres, C.J.2
Resek, J.E.3
McLaughlin, M.A.4
Woodall, C.C.5
Lee, P.H.6
-
13
-
-
0031907833
-
-
For selected references, see: a
-
For selected references, see: a) A. I. Meyers, D. A. Price, Chirality, 1998, 10, 88;
-
(1998)
Chirality
, vol.10
, pp. 88
-
-
Meyers, A.I.1
Price, D.A.2
-
14
-
-
0030858177
-
-
b) M. P. Sibi, J. Lu, J. Edwards, J. Org. Chem. 1997, 62, 5864;
-
(1997)
J. Org. Chem
, vol.62
, pp. 5864
-
-
Sibi, M.P.1
Lu, J.2
Edwards, J.3
-
15
-
-
0000539131
-
-
c) K. C. Nicolaou, P. S. Baran, Y.-L. Zhong, J. A. Vega, Angew. Chem. 2000, 112, 2625;
-
(2000)
Angew. Chem
, vol.112
, pp. 2625
-
-
Nicolaou, K.C.1
Baran, P.S.2
Zhong, Y.-L.3
Vega, J.A.4
-
18
-
-
0035807581
-
-
e) D. A. Evans, E. Hu, J. S. Tedrow, Org. Lett. 2001, 3, 3133;
-
(2001)
Org. Lett
, vol.3
, pp. 3133
-
-
Evans, D.A.1
Hu, E.2
Tedrow, J.S.3
-
19
-
-
0037123433
-
-
f) H. Lu, Z. Su, L. Song, P. S. Mariano, J. Org. Chem. 2002, 67, 3525.
-
(2002)
J. Org. Chem
, vol.67
, pp. 3525
-
-
Lu, H.1
Su, Z.2
Song, L.3
Mariano, P.S.4
-
20
-
-
17444375359
-
-
a) J. T. Suri, D. B. Ramachary, C. F. Barbas III, Org. Lett. 2005, 7, 1383;
-
(2005)
Org. Lett
, vol.7
, pp. 1383
-
-
Suri, J.T.1
Ramachary, D.B.2
Barbas III, C.F.3
-
21
-
-
33646508100
-
-
b) J. T. Suri, S. Mitsumori, K. Albertshofer, F. Tanaka, C. F. Barbas III, J. Org. Chem. 2006, 71, 3822;
-
(2006)
J. Org. Chem
, vol.71
, pp. 3822
-
-
Suri, J.T.1
Mitsumori, S.2
Albertshofer, K.3
Tanaka, F.4
Barbas III, C.F.5
-
22
-
-
37549007698
-
-
c) S. S. V. Ramasastry, K. Albertshofer, N. Utsumi, F. Tanaka, C. F. Barbas III, Angew. Chem. 2007, 119, 5668;
-
(2007)
Angew. Chem
, vol.119
, pp. 5668
-
-
Ramasastry, S.S.V.1
Albertshofer, K.2
Utsumi, N.3
Tanaka, F.4
Barbas III, C.F.5
-
24
-
-
34548192245
-
-
d) N. Utsumi, M. Imai, F. Tanaka, S. S. V. Ramasastry, C. F. Barbas III, Org. Lett. 2007, 9, 3445;
-
(2007)
Org. Lett
, vol.9
, pp. 3445
-
-
Utsumi, N.1
Imai, M.2
Tanaka, F.3
Ramasastry, S.S.V.4
Barbas III, C.F.5
-
27
-
-
27944439809
-
-
f) D. Enders, C. Grondal, M. Vrettou, G. Raabe, Angew. Chem. 2005, 117, 4147;
-
(2005)
Angew. Chem
, vol.117
, pp. 4147
-
-
Enders, D.1
Grondal, C.2
Vrettou, M.3
Raabe, G.4
-
38
-
-
27944439809
-
-
a) D. Enders, C. Grondal, M. Vrettou, G. Raabe, Angew. Chem. 2005, 117, 4147;
-
(2005)
Angew. Chem
, vol.117
, pp. 4147
-
-
Enders, D.1
Grondal, C.2
Vrettou, M.3
Raabe, G.4
-
40
-
-
33751325872
-
-
b) D. Enders, C. Grondal, M. Vrettou, Synthesis 2006, 21, 3597.
-
(2006)
Synthesis
, vol.21
, pp. 3597
-
-
Enders, D.1
Grondal, C.2
Vrettou, M.3
-
41
-
-
33846198424
-
-
a) S. S. V. Ramasastry, H. Zhang, F. Tanaka, C. F. Barbas III, J. Am. Chem. Soc. 2007, 129, 288;
-
(2007)
J. Am. Chem. Soc
, vol.129
, pp. 288
-
-
Ramasastry, S.S.V.1
Zhang, H.2
Tanaka, F.3
Barbas III, C.F.4
-
42
-
-
37649024285
-
-
[4c,d,7a] Córdova et al. published related results; P. Dziedzic, I. Ibrahem, A. H. Córdova, Tetrahedron Lett. 2008, 49, 803.
-
[4c,d,7a] Córdova et al. published related results; P. Dziedzic, I. Ibrahem, A. H. Córdova, Tetrahedron Lett. 2008, 49, 803.
-
-
-
-
43
-
-
31944446866
-
-
a) S. Mitsumori, H. Zhang, P. H.-Y. Cheong, K. N. Houk, F. Tanaka, C. F. Barbas III, J. Am. Chem. Soc. 2006, 128, 1040;
-
(2006)
J. Am. Chem. Soc
, vol.128
, pp. 1040
-
-
Mitsumori, S.1
Zhang, H.2
Cheong, P.H.-Y.3
Houk, K.N.4
Tanaka, F.5
Barbas III, C.F.6
-
44
-
-
33746606463
-
-
b) H. Zhang, M. Mifsud, F. Tanaka, C. F. Barbas III, J. Am. Chem. Soc. 2006, 128, 9630;
-
(2006)
J. Am. Chem. Soc
, vol.128
, pp. 9630
-
-
Zhang, H.1
Mifsud, M.2
Tanaka, F.3
Barbas III, C.F.4
-
45
-
-
38349089956
-
-
c) H. Zhang, S. Mitsumori, N. Utsumi, M, Imai, N. Garcia-Delgado, M. Mifsud, K. Albertshofer, P. H.-Y. Cheong, K. N. Houk, F. Tanaka, C. F. Barbas III J. Am. Chem. Soc. 2008, 130, 875.
-
(2008)
J. Am. Chem. Soc
, vol.130
, pp. 875
-
-
Zhang, H.1
Mitsumori, S.2
Utsumi, N.3
Imai, M.4
Garcia-Delgado, N.5
Mifsud, M.6
Albertshofer, K.7
Cheong, P.H.-Y.8
Houk, K.N.9
Tanaka, F.10
Barbas III, C.F.11
-
46
-
-
28444445588
-
-
For other anti-Mannich reactions based on enamine catalysis, see: d T. Kano, Y. Yamaguchi, O. Tokuda, K. Maruoka, J. Am. Chem. Soc. 2005, 127, 16408;
-
For other anti-Mannich reactions based on enamine catalysis, see: d) T. Kano, Y. Yamaguchi, O. Tokuda, K. Maruoka, J. Am. Chem. Soc. 2005, 127, 16408;
-
-
-
-
47
-
-
29844457732
-
-
e) J. Franzen, M. Marigo, D. Fielenbach, T. C. Wabnitz, A. Kjaersgaard, K. A. Jorgensen, J. Am. Chem. Soc. 2005, 127, 18296;
-
(2005)
J. Am. Chem. Soc
, vol.127
, pp. 18296
-
-
Franzen, J.1
Marigo, M.2
Fielenbach, D.3
Wabnitz, T.C.4
Kjaersgaard, A.5
Jorgensen, K.A.6
-
48
-
-
33947545143
-
-
f) L. Cheng, X. Wu, Y. Lu, Org. Biomol. Chem. 2007, 5, 1018.
-
(2007)
Org. Biomol. Chem
, vol.5
, pp. 1018
-
-
Cheng, L.1
Wu, X.2
Lu, Y.3
-
49
-
-
53849115904
-
H-tetrazole were the best choices considering the reaction rate, yield, and selectivity (data not shown)
-
Solvent and additive screening at room temperature showed that NMP and 5-methyl-1, as an acid co-catalyst
-
Solvent and additive screening at room temperature showed that NMP and 5-methyl-1H-tetrazole were the best choices considering the reaction rate, yield, and selectivity (data not shown). 5-Methyl-1H-tetrazole acts as an acid co-catalyst.
-
5-Methyl-1H-tetrazole acts
-
-
-
50
-
-
53849117281
-
-
[5]
-
[5]
-
-
-
-
51
-
-
0344391932
-
-
and references cited therein
-
A. Tarrade, D. Dauban, R. H. Dodd, J. Org. Chem. 2003, 68, 9521, and references cited therein.
-
(2003)
J. Org. Chem
, vol.68
, pp. 9521
-
-
Tarrade, A.1
Dauban, D.2
Dodd, R.H.3
-
52
-
-
53849087657
-
-
[8e]
-
[8e]
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-
-
-
53
-
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53849148045
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Poor enantioselectivity was observed in the β-proline catalyzed Mannich reaction with Bn-protected DHA and ethyl glyoxylate imine; dr 1.4:1 (anti:syn) and 45% ee anti, see ref.[8c
-
[8c]
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