Msh2 promoter region hypermethylation as a marker of aging-related deterioration in old retired female breeder mice

Biogerontology

Volumn 9, Issue 5, 2008, Pages 325-334

  Conde Pérezprina, Juan C ^a   Luna López, Armando ^a   López Diazguerrero, Norma E ^a   Damián Matsumura, Pablo ^a   Zentella, Alejandro ^b   Königsberg, Mina ^a  

^a DEPARTAMENTO DE QUÍMICA   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Aging; Breeding; Epigenetics; Methylation; MSH2; Silencing

Indexed keywords

BISULFITE; MESSENGER RNA; PROTEIN MSH2;

AGING; ANIMAL EXPERIMENT; ARTICLE; BREEDING; CONTROLLED STUDY; DNA HYPERMETHYLATION; DNA METHYLATION; DNA MODIFICATION; EPIGENETICS; FEMALE; GENE SILENCING; GENETIC ASSOCIATION; GENETIC MARKER; MOUSE; NONHUMAN; NULLIPARA; PRIORITY JOURNAL; PROMOTER REGION; RESTRICTION MAPPING;

AGING; ANIMALS; BREEDING; DNA DAMAGE; DNA METHYLATION; DNA REPAIR; EPIGENESIS, GENETIC; FEMALE; GENETIC MARKERS; MICE; MUTS HOMOLOG 2 PROTEIN; PROMOTER REGIONS (GENETICS); REPRODUCTION;

EID: 50649102558     PISSN: 13895729     EISSN: 15736768     Source Type: Journal    
DOI: 10.1007/s10522-008-9144-8     Document Type: Article

References (57)

1. Ahuja N, Issa JP (2000) Aging, methylation and cancer. Histol Histopathol 15:835-842
2. Akintola AD, Crislip ZL, Catania JM, Zimmer WE, Burgahrdt RC, Parrish AR (2007) Promoter methylation is associated with the age-dependent loss of N-cadherin in the rat kidney. Am J Physiol Renal Physiol (in press)
3. Altamirano A (1994) Manual de manejo de animales de laboratorio. Facultad de Estudios Superiores Veterinaria. Zaragoza UNAM, México
4. Bennett-Baker PE, Wilkowski J, Burke DT (2003) Age-associated activation of epigenetically repressed genes in the mouse. Genetics 165:2055-2062
5. Bernstein EE, Meissner A, Lander ES (2007) The mammalian epigenome. Cell 128:669-681
6. Bjornsson HT, Fallin MD, Feinberg AP (2004) An integrated epigenetic and genetic approach to common human disease. Trends Genet 20:350-358
7. Bohr VA (2002) Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells. Free Radic Biol Med 32:804-812
8. Campbell MR, Wang Y, Andrew SE, Liu Y (2006) MSH2 deficiency leads to chromosomal abnormalities, centrosome amplification, and telomere capping defect. Oncogene 25:2531-2536
9. Candore G, Balistreri CR, Listi F, Grimaldi MP, Vasto S, Colonna-Romano G, Franceschi C, Lio D, Caselli G, Caruso C (2006) Immunogenetics, gender, and longevity. Ann NY Acad Sci 1089:516-537
10. Chan PA, Duraisamy S, Miller PJ, Newell JA, McBride C, Bond JP, Raeveera T, Ollila S, Nyström M, Grimm AJ, Christodoulou J, Oetting WS, Greenbelatt MS (2007) Interpreting missense variants: Comparing computational methods in human disease genes CDKN2A, MLH1, MSH2, MECP2, and tyrosinase (TYR). Hum Mutat 28:683-693
11. Chomczynski P (1993) A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples. Biotechniques 15:532-537
12. Degtyareva NP, Greenwell P, Hofmann RE, Hengartner MO, Zhang L, Culotti JG, Petes TD (2002) Caenorhabditis elegans DNA mismatch repair gene msh-2 is required for microsatellite stability and maintenance of genome integrity. Proc Natl Acad Sci USA 99:2158-2163
13. Estes S, Phillips PC, Denver DR, Thomas WK, Lynch M (2004) Mutation accumulation in populations of varying size: The distribution of mutational effects for fitness correlates in Caenorhabditis elegans. Genetics 166:1269-1279
14. Feinberg AP, Oshimura M, Barrett JC (2002) Epigenetic mechanisms in human disease. Cancer Res 62:6784-6787
15. Finch CE, Pike MC, Witten M (1990) Slow mortality rate accelerations during aging in some animals approximate that of humans. Science 249:902-905
16. Fraga MF, Agrelo R, Esteller M (2007) Cross-talk between aging and cancer: The epigenetic language. Ann NY Acad Sci 1100:60-74
17. Garcia-Manero G, Daniel J, Smith TL, Kornblau SM, Lee MS, Kantarjian HM, Issa JP (2002) DNA methylation of multiple promoter-associated CpG islands in adult acute lymphocytic leukemia. Clin Can Res 8:2217-2224
18. Goldberg M, Rummelt C, Laerm A, Helmbold P, Holbach LM, Ballhausen WG (2006) Epigenetic silencing contributes to frequent loss of the fragile histidine triad tumour suppressor in basal cell carcinomas. Br J Dermatol 155:1154-1158
19. Grunau C, Sanchez C, Ehrlich M, Van der Bruggen P, Hindermann W, Rodriguez C, Krieger S, Dubeau L, Fiala E, De Sario A (2005) Frequent DNA hypomethylation of human juxtacentromeric BAGE loci in cancer. Genes Chrom Cancer 43:11-24
20. Harfe BD, Jinks-Robertson S (2000) Sequence composition and context effects on the generation and repair of frameshift intermediates in mononucleotide runs in Saccharomyces cerevisiae. Genetics 156:571-578
21. Hasty P, Vijg J (2002) Aging. Genomic priorities in aging. Science 296:1250-1251
22. Hughes S, Jones LJ (2007) The use of whole genome amplified DNA as a control for methylation specific PCR, pyrosequencing, bisulfite sequencing and methylation-sensitive restriction enzyme PCR. BMC Mol Biol 8(1):91
23. Imam SZ, Karahalil B, Hogue BA, Souza-Pinto NC, Bohr VA (2006) Mitochondrial and nuclear DNA-repair capacity of various brain regions in mouse is altered in an age-dependent manner. Neurobiol Aging 27:1129-1136
24. Issa JP (2002) Epigenetic variation and human disease. J Nutr 132:2388S-2392S
25. Issa JP (2003) Age-related epigenetic changes and the immune system. Clin Immunol 109:103-108
26. Issa JP (2007) DNA Methylation in cancer protocols. Bisulfite-PCR for Restriction Analysis and/or Sequencing. http://www.mdanderson.org/ departments/methylation/display. Cited 11 Dic 2007. The University of Texas MD Anderson Cancer Center.
27. Jiricny J (2006) The multifaceted mismatch-repair system. Nature Rev 7:335-346
28. Jun S, Kim TG, Ban C (2006) DNA mismatch repair system classical and fresh roles. FEBS J 273:1609-1619
29. Kim JY, Siegmund KD, Tavaté S, Shibata D (2005) Age-related human small intestine methylation: Evidence for stem cell niches. BMC Med 3:10
30. Königsberg M, López-Diazguerrero NE, Rivera-Martinez LP, González-Puertos VY, González-Vieira R, Gutiérrez-Ruiz MC, Zentella A (2007) The physiological deterioration associated to breeding in female mice: A model for the study of senescence and aging. Comp Biochem Physiol A 146:695-701
31. López-Araiza H, Ventura JL, López-Diazguerrero NE, González-Marquez H, Gutiérrez-Ruíz MC, Zentella DA, Königsberg FM (2006) Organ- and Tissue-specific Alterations in the Anti-apoptotic Protein Bcl-2 in CD1 Female Mice of Different Ages. Biogerontology 7:63-67
32. López-Diazguerrero NE, Luna-López A, Gutiérrez-Ruiz MC, Zentella A, Konigsberg M (2005) Susceptibility of DNA to oxidative stressors in young and aging mice. Life Sci 77:2840-2854
33. Madia F, Gattazzo C, Fabrizio P, Longo VD (2007) A simple model system for age-dependent DNA damage and cancer. Mech Ageing Dev 128:45-49
34. Matos HR, Capelozzi VL, Gomes OF, Di Mascio P, Medeiros MH (2001) Lycopene inhibits DNA damage and liver necrosis in rats treated with ferric nitiolacetate. Arch Biochem Biophys 396:171-177
35. Matsuo K, Silke J, Gramatikoff K, Schaffner W (1994) The CpG-specific methylase SssI has topoisomerase activity in the presence of Mg2+. Nucleic Acids Res 22:5354-5359
36. Neri S, Pawelec G, Facchini A, Mariani E (2007) Microsatellite instability and compromised mismatch repair gene expression during in vitro passaging of monoclonal human T lymphocytes. Rejuvenation Res 10:145-156
37. Ottaviano Y, Issa JP, Parl FF, Smith HS, Baylin SB, Davidson NE (1994) Methylation of the estrogen receptor gene CpG island marks loss of estrogen receptor expression in human breast cancer cells. Cancer Res 54:2552-2555
38. Park Y, Gerson SL (2005) DNA repair defects in stem cell function and aging. Ann Rev Med 56:495-508
39. Phelan JP, Rose MR (2005) Why dietary restriction substantially increases longevity in animal models but won't in humans. Age Res Rev 4:339-350
40. Ravindran CR, Ticku MK (2005) Methylation of NMDA receptor NR2B gene as a function of age in the mouse brain. Neurosci Lett 380:223-228
41. Richardson B (2003) Impact of aging on DNA methylation. Age Res Rev 2:245-261
42. Rossi DJ, Bryder D, Seita J, Nussenzweig A, Hoeijmarkers J, Wisseman IL (2007) Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature 447:725-729
43. Russel ES (1964) Lifespan and aging patterns. In: Green EL (ed) Biology of the Laboratory Mouse. Dover Publications. Inc., New York, pp 685-692
44. Schmitt E, Paquet C, Beauchemin M, Bertrand R (2007) DNA-damage response network at the crossroads of cell-cycle checkpoints, cellular senescence and apoptosis. J Zhejiang Univ Sci B 8:377-397
45. Siegmund KD, Connor CM, Campan M, Long TI, Weisenberg DJ, Biiniskiewicz D, Jeanish R, Laird PW, Akbarian S (2007) DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons. PLoS ONE 2(9):e895
46. So K, Tamura G, Honda T, Homma N, Waki T, Togawa N, Nishizuka S, Motoyama T (2006) Multiple tumor suppressor genes are increasingly methylated with age in non-neoplastic gastric epithelia. Cancer Sci 97:1155-1158
47. Takahashi Y, Moriwaki S, Sugiyama Y, Endo Y, Yamazaki K, Mori T, Takigawa M, Inoue S (2005) Decreased gene expression responsible for post-ultraviolet DNA repair synthesis in aging: A possible mechanism of age-related reduction in DNA repair capacity. J Inv Dermatol 124:435-442
48. Tuirán R, Partida V, Mojarro O, Zúñiga E (2002) Tendencias y perspectivas de la fecundidad. La Situación Demográfica de México. Consejo Nacional de Población (CONAPO). México City, pp 29-48
49. Villarreal-Molina MT, Aguilar-Salinas CA, Rodriguez-Cruz M, Riano D, Villalobos-Comparan M, Coral-Vazquez R, Menjivar M, Yescas-Gomez P, Konigsoerg-Fainstein M, Romero-Hidalgo S, Tusie-Luna MT, Canizales-Quinteros S (2007) The ATP-binding cassette transporter A1 R230C variant affects HDL cholesterol levels and BMI in the Mexican population. Diabetes 56:1881-1887
50. Wang L, Hirayasu K, Ishisawa M, Kobayash Y (1994) Purification of genomic DNA from human whole blood by isopropanol-fractionation with concentrated Nal and SDS. Nucl Acids Res 22:1774-1775
51. Xiong Z, Laird PW (1997) COBRA: A sensitive and quantitative DNA methylation assay. Nucleic Acids Res 25:2532-2534
52. Xu XL, Yu J, Zhang HY, Sun MH, Gu J, Du X, Shi DR, Wang P, Yang ZH, Zhu JD (2004) Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis. World J Gastroenterol 10:3441-3454
53. Yang AS, Estécio MRH, Doshi K, Kondo Y, Tajara EH, Issa JP (2004) A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements. Nucl Acids Res 32:1-6
54. Yuasa Y (2002) DNA methylation in cancer and ageing. Mech Ageing Dev 123:1649-1654
55. Zeng X, Kinsella TJ (2007) A novel role for DNA mismatch repair and the autophagic processing of chemotherapy drugs in human tumor cells. Autophagy 3:368-370
56. Zúñiga E, Durán D, Logia S (2002) La salud reproductiva en las entidades federativas: Una mirada a través de los índices de rezago. La Situación Demográfica de México. Consejo Nacional de Población (CONAPO). Mexico City, pp 49-66.
57. Zurcher C, Van Zwieten MJ, Solleveld HA, Hollander CF (1982) The mouse in biomedical research. In: Foster HL, Small JD, Fox JG (eds) Experimental biology and oncology, Inc. New York, Academic Press, pp 325-345