Low-level laser therapy in the prevention and treatment of chemotherapy-induced oral mucositis in young patients

Photomedicine and Laser Surgery

Volumn 26, Issue 4, 2008, Pages 393-400

  Abramoff, Meire Maman Fracher ^d   Lopes, Nilza Nelly Fontana ^a   Lopes, Luciana Almeida ^b   Dib, Luciano Lauria ^c   Guilherme, Arnaldo ^a   Caran, Eliana Monteiro ^a   Barreto, Adriana Delboni ^d   Lee, Maria Lucia Martinho ^a   Petrilli, Antônio Sérgio ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b Research and Education Center for Photo Therapy in Health Sciences (NUPEN)   (Brazil)

^c PAULISTA UNIVERSITY   (Brazil)

^d Federal University of São Paulo ^*  (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

MUCOSITIS; ORAL MUCOSITIS;

BIOTECHNOLOGY; CHEMOTHERAPY; ELECTRIC INSTRUMENT TRANSFORMERS; IRRADIATION; LASER TISSUE INTERACTION; LASERS;

PATIENT TREATMENT;

ASPARAGINASE; CISPLATIN; CYCLOPHOSPHAMIDE; CYTARABINE; DAUNORUBICIN; DEXAMETHASONE; DOXORUBICIN; ETOPOSIDE; IFOSFAMIDE; MERCAPTOPURINE; MESNA; METHOTREXATE; TIOGUANINE; VINCRISTINE;

ANALGESIA; ANTIBODY BLOOD LEVEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CANCER CHEMOTHERAPY; CLINICAL ARTICLE; CLINICAL EFFECTIVENESS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; DRUG MEGADOSE; FEMALE; GRANULOCYTE; GRANULOCYTOPENIA; HUMAN; LOW LEVEL LASER THERAPY; LYMPHATIC LEUKEMIA; MALE; MULTIPLE CYCLE TREATMENT; ORAL MUCOSAL DISEASE; ORAL MUCOSITIS; OSTEOSARCOMA; RANDOMIZED CONTROLLED TRIAL; STATISTICAL SIGNIFICANCE; VISUAL ANALOG SCALE;

ADOLESCENT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHILD; FEASIBILITY STUDIES; FEMALE; GRANULOCYTES; HUMANS; LASER THERAPY, LOW-LEVEL; LEUKOCYTE COUNT; MALE; MOUTH MUCOSA; PILOT PROJECTS; PROSPECTIVE STUDIES; STOMATITIS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 50649101908     PISSN: 15495418     EISSN: None     Source Type: Journal    
DOI: 10.1089/pho.2007.2144     Document Type: Article

References (61)

1. Sonis, S.T., Oster, G., Fuchs, H., et al. (2001). Oral mucositis and the clinical and economic outcomes of hematopoietic stem cell transplantation. J. Clin. Oncol. 19, 2201-2205.
2. Bellm, L.A., Epstein, J.B., Rose-Ped, A., et al. (2000). Patients reports of complications of bone marrow transplantation. Support Care Cancer. 8, 33-39.
3. Cheng, K.K.-F. (2007). Oral mucositis, dysfunction, and distress in patients undergoing cancer therapy. J Clin. Nursing. OnlineEarly Articles. Available at: http://www.blackwellsynergy.com/doi/abs/10.1111/j.1365-2702.2006. 01618.x
4. National Cancer Institute. (2004). Oral complication of chemotherapy and head/neck radiation PDQ, pp. 1-49. Available at: http://www.cancer.gov/ cancertopics/pdq/supportivecare/oralcomplications/HealthProfessional
5. Sonis, S.T., Sonis, A.L., and Lieberman, A. (1978). Oral complications in patients receiving treatment for malignancy other than head and neck. J. Am. Dent. Assoc. 97, 468-472.
6. Lockhart, P.B., and Sonis, S.T. (1979). Relationship of oral complications to peripheral blood leukocyte and platelet counts in patients receiving cancer chemotherapy. Oral Surg. Oral Med. Oral Pathol. 48, 21-28.
7. Sonis, S.T. (2004). The pathobiology of mucositis. Nat. Rev. Cancer. 4, 277-284.
8. Sonis, S.T. (2002). The biologic role of nuclear factor-κB in disease and its potential involvement in mucosal injury associated with antineoplastic therapy. Crit. Rev. Oral Biol. Med. 13, 300-309.
9. Sonis, S.T., Peterson, R.L., Edwards, L.J., et al. (2000). Defining mechanisms of action of interleukin-11 on the progression of radiation induced oral mucositis in hamsters. Oral Oncol. 36, 373-381.
10. Paris, F., Fuks, Z., Kang, A., et al. (2001). Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice. Science. 293, 293-297.
11. McCarty, G.M., Awde, J.D., Ghandi, H., et al. (1998). Risk factors associated with mucositis in cancer patients receiving 5- fluorouracil. Oral Oncol. 34, 484-490.
12. Spielberger, R., Stiff, P., Bensinger, W., et al. (2004). Palifermin for oral mucositis after intensive therapy for hematologic cancers. N. Engl. J. Med. 351, 2590-2598.
13. Karu, T., Ryabykh, T.P., Fedoseyeva, G.E., et al. (1989). Helium-neon laser-induced respiratory burst of phagocyte cells. Lasers Surg. Med. 9, 585-588.
14. Karu, T. (1999). Primary and secondary mechanisms of action of visible to near-IR radiation on cells. J. Photochem. Photobiol. B. Biol. 49, 1-17.
15. Mester, E., Ludany, M., Sellyei, M., et al. (1968). The stimulating effect of low power laser ray on biological systems. Laser Rev. 1, 3.
16. Mester, A.F., and Snow, J.B. (1990). Photochemical effects of low-intensity laser irradiation on wound healing and on the maturation and regeneration of olfactory neuroepithelial explants. J. Clinical Laser Med. Surg. 8, 31-33.
17. Miró, L., Coupe, M., Charras, C., et al. (1984). Estudio capiloroscópico de la acción de un láser de AsGa sobre la microcirculación. Inv. Clin. Laser 1, 9-14.
18. Gal, D., Chokshi, S.K., Mosseri, M., et al. (1992). Percutaneous delivery of low laser energy reverses histamine-induced spasm in atherosclerotic Yucatan micro-suine. Circulation. 85, 756-768.
19. Maegawa, Y., Itoh, T., Hosokawa, T. et al. (2000). Effects of near-infrared low-level laser irradiation on microcirculation. Lasers Surg. Med. 27, 427-437.
20. Ihsan, M.F.R. (2005). Low-level laser therapy accelerates collateral circulation and enhances microcirculation. Photomed. Laser Surg. 23, 289-294.
21. Lievens, P. (1988). Effects of laser treatment on the lymphatic system and wound healing. LASER. J. Eur. Med. Laser Ass. 1, 12.
22. Lievens, P.C. (1991). The effect of IR laser irradiation on the vasomotricity of the lymphatic system. Laser Med. Sci. 6, 189-191.
23. Almeida Lopes, L., and Lopes, A. (2006). Técnica da Drenagem Linfática Ativada por Laserterapia, in: Atualização Clínica em Odontologia. L.L. Dib, and M.S. Saddy, (eds.). São Paulo: Editora Artes Médicas v.1, pp. 327-340.
24. Colls, J. (1986). La terapia laser, hoy. Barcelona: Centro Documentación Laser, pp. 39-70.
25. Ataka, I., Kazuhiro, K., Kenji, Y., et al. (1989). Studies of Nd:YAG low power laser irradiation on stellate ganglion, in: Lasers in Dentistry. H. Yamamoto, K. Atsumi, and H. Kusakari, (eds.). Amsterdam: Elsevier, pp. 271-276.
26. Honmura, A., Ishii, A., Yanase, M., et al. (1993). Analgesic effect of Ga-Al-As diode laser irradiation on hyperalgesia in carrageenan-induced inflammation. Lasers Surg. Med. 13, 463-469.
27. Laakso, E., and Cabot, P.J. (2005). Nociceptive scores and endorphin-containing cells reduced by low-level laser therapy (LLLT) in inflamed paws of Wistar rat. Photomed. Laser Surg. 23, 32-35.
28. Ferreira, D.M., Zângaro, R.A., Balbin Villaverde, A., et al. (2005). Analgesic effect of He-Ne (632.8 nm) low-level laser therapy on acute inflammatory pain. Photomed. Laser Surg. 23, 177-181.
29. Bjordal, M.J., Johnson, M.I., Iversen, V., et al. (2006). Low-level laser therapy in acute pain: A systematic review of possible mechanisms of action and clinical effects in randomized placebo-controlled trials. Photomed Laser Surg. 24, 158-168.
30. Enwemeka, C.S. (1988). Laser biostimulation of healing wounds: specific effects and mechanism on action. J. Orthop. Sports Phys. Ther. 9, 333-338.
31. Steinlechner, C.W.B., and Dyson, M. (1993). The effects of low level laser therapy on the proliferation of keratinocytes. Laser Ther. 5, 65-73.
32. Mognato, M., Squizzato, F., Facchin, F., et al. (2004). Cell growth modulation of human cells irradiated in vitro with low-level laser therapy. Photomed Laser Surg. 22, 523-526.
33. Enwemeka, C.S. (1992). Ultrastructural morphometry of membrane-bound intracytoplasmatic collagen fibrils in tendon fibroblasts exposed to He-Ne laser beam. Tissue Cell. 24, 511-523.
34. Lubart, R., Friedmann, H., Sinykov, M., et al. (1995). Biostimulation of photosensitized fibroblasts by low incident levels of visible light energy. Laser Ther. 7, 101-106.
35. Almeida-Lopes, L., Rigau, J., Jaeger, M.M.M., et al. (1998). Acción del láser a baja densidad de potencia en la proliferación in vitro de fibroblastos de procedencia humana. Bol. SELMQ Dic. 14, 14-18.
36. Almeida-Lopes, L., Rigau, J., Zângaro, R.A., Guidugli-Neto, J., and Marques Jaeger, M.M. (2001). Comparison of the low level laser therapy effects on cultured human gingival fibroblasts proliferation using different irradiance and same fluence. Lasers Surg. Med. 29, 179-184.
37. Almeida-Lopes, L. (2003). Análise in vitro da Proliferação Celular de Fibroblastos de Gengiva Humana Tratados com Laser de Baixa Intensidade Utilizando Diferentes Parâmetros de Irradiação [Ph.D. thesis for degree in materials engineering, in Portuguese]. Interunidades IFSC/IQSC/EESC, São Paulo University, São Carlos, Brazil.
38. Hawkins, D., and Abrahamse, H. (2006). Effect of multiple exposures of low-level laser therapy on the cellular responses of wounded human skin fibroblasts. Photomed Laser Surg. 24, 705-714.
39. Enwemeka, C.S., Rodriguez, O., Gall, N.G., et al. (1990). Morphometrics of collagen fibril populations in He-Ne laser photostimulated tendons. J. Clin. Laser Med. Surg. 8, 151-156.
40. Skinner, S.M., Gage, J.P., Wilce, P.A., et al. (1996). A preliminary study of the effects of laser irradiation on collagen metabolism in cell culture. Aust. Dent. J. 41, 188-192.
41. Reddy, G.K., Stehno-Bittel, L., and Enwemeka, C.S. (2001). Laser photostimulation accelerates wound healing in diabetic rats. Wound Repair Regen. 9, 248-255.
42. Pereira, A.N., Eduardo, C.P., Matson, E., et al. (2002). Effect of low-power laser irradiation on cell growth and procollagen synthesis of cultured fibroblasts. Lasers Surg. Med. 31, 263-267.
43. Ciais, G., Namer, M., Schneider, M., et al. (1992). La laserthérapie dans la prévention et le traitement des mucites liées á la chimiothérapie anticancéreuse. Bull. Cancer 79, 183-191.
44. Barasch, A., Peterson, D.E., Tanzer, J.M., et al. (1995). Helium-neon laser effects on conditioning-induced oral mucositis in bone marrow transplantation patients. Cancer. 76, 2550-2556.
45. Cowen, D., Tardieu, C., Schubert, M., et al. (1997). Low energy helium-neon laser in the prevention of oral mucositis in patients undergoing bone marrow transplant: results of a double blind randomized trial. Int. J. Radiat. Oncol. Biol. Phys. 38, 697-793.
46. Bensadoun, R.J., Franquim, J.C., Ciais, G., et al. (1999). Low-energy He/Ne laser in the prevention of radiation-induced mucositis. A multicenter phase III randomized study in patients with head and neck cancer. Support Care Cancer. 7, 244-252.
47. Migliorati, C., Massumoto, C., de Paula Eduardo, F., et al. (2001). Low-energy laser therapy in oral mucositis. J. Oral Laser Applications 1, 97-101.
48. Wong, S.F., and Wilder-Smith, P. (2002). Pilot study of laser effects on oral mucositis in patients receiving chemotherapy. Cancer J. 8, 247-254.
49. Sandoval, R.L., Koga, D.H., Buloto, L.S., et al. (2003). Management of chemo and radiotherapy induced oral mucositis with low-energy laser: initial results of A.C. Camargo Hospital. J. Appl. Oral Sci. 11, 337-341.
50. Genot, M.T., and Klastersky, J. (2005). Low-level laser for prevention and therapy of oral mucositis induced by chemotherapy or radiotherapy. Curr. Opin. Oncol. 17, 236-240.
51. Nes, A.G., and Posso, M.B.S. (2005). Patients with moderate chemotherapy-induced mucositis: pain therapy using low intensity lasers. Int. Nurs. Rev. 52, 68-72.
52. Antunes, H.S., de Azevedo, A.M., da Silva Bouzas, L.F., et al. (2007). Low-power laser in the prevention of induced oral mucositis in bone marrow transplantation patients: a randomized trial. Blood. 109, 2250-2255.
53. Jaguar, G.C., Prado, J.D., Nishimoto, I.N., et al. (2007). Low-energy laser therapy for prevention of oral mucositis in hematopoietic stem cell transplantation. Oral Dis. (OnlineEarly Articles). Available at: http://www.blackwell-synergy.com/doi/abs/10.1111/j.1601-0825.2006.01330.x
54. Schubert, M.M., Eduardo, F.P., Guthrie, K.A., et al. (2007). A phase III randomized double-blind placebo-controlled clinical trial to determine the efficacy of low level laser therapy for the prevention of oral mucositis in patients undergoing hematopoietic cell transplantation. Support. Care Cancer (Online First). Available in: http://www.springerlink.com/content/ 910406505t28l259/
55. Rubenstein, E.B., Peterson, D.E., Schubert, M., et al. (2004). Clinical practice guidelines for the prevention and treatment of cancer therapy-induced oral and gastrointestinal mucositis. Cancer. 100, 2026-2046.
56. Keefe, D.M., Schubert, M.M., Elting, L.S., et al. (2007). Updated clinical practice guidelines for the prevention and treatment of mucositis. Wiley InterScience. Available at: http://www.capitalhospice.org/institute/ education/journalclub/documents/OralMucositis1.pdf
57. Cancer Therapy Evaluation Program. (1998). Common Toxicity Criteria Version 2.0. DCTD, NCI, NIH, DHHS. Available at: http://ctep.cancer.gov/forms/ CTCv20_4-30-992.pdf.
58. McGrath, P.J., Beyer, J., Cleeland, C., et al. (1990). Report of the subcommittee on assessment and methodologic issues in the management of pain in childhood cancer. Pediatrics. 86, 814-817.
59. Whelan, H.T., Connelly, J.F., Hodgson, B.D., et al. (2002). NASA light-emitting diodes for the prevention of oral mucositis in pediatric bone marrow transplant patients. J Clin. Laser Med. Surg. 20, 319-324.
60. Corti, L., Chiarion-Sileni, V., and Aversa, S. (2006). Treatment of chemotherapy-induced oral mucositis with light-emitting diode. Photomed. Laser Surg. 24, 207-213.
61. Karu, T.J., Tiphlova, O.A., Letokhov, V.S., et al. (1983). Stimulation of E. coli growth by laser and incoherent red light. Nuov. Cim. D2, 1138-1144.