Low-energy He/Ne laser in the prevention of radiation-induced mucositis: A multicenter phase III randomized study in patients with head and neck cancer

Supportive Care in Cancer

Volumn 7, Issue 4, 1999, Pages 244-252

  Bensadoun, R J ^a   Franquin, J C ^b   Ciais, G ^a   Darcourt, V ^a   Schubert, M M ^c   Viot, M ^a   Dejou, J ^b   Tardieu, C ^b   Benezery, K ^a   Nguyen, T D ^d   Laudoyer, Y ^a   Dassonville, O ^a   Poissonnet, G ^a   Vallicioni, J ^a   Thyss, A ^a   Hamdi, M ^e   Chauvel, P ^a   Demard, F ^a  

^a CENTRE ANTOINE LACASSAGNE   (France)

^b AIX MARSEILLE UNIVERSITY   (France)

^c UNIVERSITY OF WASHINGTON   (United States)

^d INSTITUT JEAN GODINOT   (France)

^e Fradama SA   (Switzerland)

Author keywords

Head and neck cancer; Low energy laser; Mucositis; Radiotherapy

Indexed keywords

ADULT; AGED; ARTICLE; CANCER RADIOTHERAPY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HEAD AND NECK CARCINOMA; HELIUM NEON LASER; HUMAN; MALE; MUCOSA INFLAMMATION; MULTICENTER STUDY; PHASE 3 CLINICAL TRIAL; PHOTOTHERAPY; PRIORITY JOURNAL; RADIATION INJURY; RANDOMIZED CONTROLLED TRIAL; STOMATITIS;

ADULT; AGED; ANALYSIS OF VARIANCE; CHI-SQUARE DISTRIBUTION; DOUBLE-BLIND METHOD; FEMALE; FOLLOW-UP STUDIES; HEAD AND NECK NEOPLASMS; HUMANS; LASERS; MALE; MIDDLE AGED; MOUTH MUCOSA; PAIN; PAIN MEASUREMENT; RADIATION DOSAGE; RADIATION INJURIES; SEVERITY OF ILLNESS INDEX; STOMATITIS; TREATMENT OUTCOME;

EID: 0032968733     PISSN: 09414355     EISSN: None     Source Type: Journal    
DOI: 10.1007/s005200050256     Document Type: Article

References (52)

1. Abou-Hashieh I, Tardieu C, Franquin JC (1997) Helium-neon laser irradiation is not a stressful treatment: a study on heat-shock protein level. Lasers Surg Med 20:451-460
2. Amdur RJ, Parsons JT, Mendenhall WM, Million RR, Cassisi NJ (1989) Split-course versus continuous-course irradiation in the postoperative setting for squamous cell carcinoma of the head and neck. Int J Radiat Oncol Biol Phys 17:279-285
3. Barasch A, Peterson D, Tanzer JM, D'Ambrosio JA, Nuki K, Schubert M, Franquin JC, Clive J, Tutschka P (1995) Helium-neon laser effects on conditioning-induced oral mucositis in bone marrow transplantation patients. Cancer 76:2550-2556
4. Bensadoun RJ, Etienne MC, Dassonville O, Chauvel P, Pivot X, Marcy PY, Prevost B, Coche-Dequeant B, Bourdin S, Vallicioni J, Poissonnet G, Courdi A, Teissier E, Lagrange L, Thyss A, Santini J, Demard F, Schneider M, Milano G (1998) Concomitant B.I.D. radiotherapy and chemotherapy with Cisplatin and 5-Fluorouracil in unresectable squamous-cell carcinoma of the pharynx: clinical and pharmacological data of a French multicenter phase II study. Int J Radiat Oncol Biol Phys 42:237-245
5. Borowski B, Benhamou E, Pico JL, Laplanche A, Margainaud JP, Hayat M (1994) Prevention of oral mucositis in patients treated with high dose chemotherapy and bone marrow transplantation: a randomised controlled trial comparing two protocols of dental care. Eur J Cancer [B] 30:93-97
6. Braverman B, McCarthy RJ, Ivankovich AD, Forde DE, Overfield Bapna MS (1989) Effect of helium-neon and infrared laser irradiation on wound healing in rabbits. Laser Surg Med 9:50-58
7. Carl W (1995) Oral complications of local and systemic cancer treatment. Curr Opin Oncol 7:320-324
8. Cartee L, Petros WP, Rosner GL, Gilbert C, Moore S, Affronti ML, Hoke SA, Hussein AM, Ross M, Rubin P, Vredenburgh JJ, Peters WP (1995) Evaluation of GM-CSF mouthwash for prevention of chemotherapy-induced mucositis : a randomized, double-blind, dose ranging study. Cytokine 7:471-477
9. Chambers MS, Toth BB, Martin JW, Fleming TJ, Lemon JC (1995) Oral and dental management of the cancer patient: prevention and treatment of complications. Support Care Cancer 3:168-175
10. Ciais G, Namer M, Schneider M, Demard F, Pourreau-Schneider N, Martin PM, Soudry M, Franquin JC, Zattara H (1992) La laserthérapie dans la prévention et le traitement des mucites liées à la chimiothérapie anticancéreuse. Bull Cancer 79:183-191
11. Conley B, Jacobs M, Suntharalingan M, Zacharski D, Ord R, Gray W, Aisner J (1997) The role of paclitaxel/carboplatin and concurrent radiotherapy in unresectable head and neck cancer: recent findings. Semin Radiat Oncol [Suppl 1]:39-41
12. Cowen D, Tardieu C, Schubert M, Peterson D, Resbeut M, Faucher C, Franquin JC (1997) Low energy helium-neon laser in the prevention of oral mucositis in patients undergoing bone marrow transplant: results of a double blind randomized trial. Int J Radiat Oncol Biol Phys 38:697-703
13. De la Torre A, Regueiro CA, Valcarcel FJ (1997) Granulocyte-macrophage colony-stimulating factor mouthwashes improve radiation mucositis in AIDS patients. Radiother Oncol 43:229-230
14. Dodd MJ, Larson PJ, Dibble SL, Mjaskowski C, Greenspan D, MacPhail L, Hauck WW, Paul SM, Ignoffo R, Shiba G (1996) Randomized clinical trial of chlorhexidine versus placebo for prevention of oral mucositis in patients receiving chemotherapy. Oncol Nurs Forum 23:921-927
15. Dreizen S (1990) Description and incidence of oral complications. Natl Cancer Inst Monogr 9:11-15
16. Duncan W, MacDougall H, Kerr GR, Downing D (1966) Adverse effect of treatment gaps in the outcome of radiotherapy for laryngeal cancer. Radiother Oncol 41:203-207
17. Gabrilove JL, Jakubowski A, Scher H, Sternberg C, Wong C, Crous J, Yagoda A, Fain K, Moore MAS, Clarkson B, Oettgen H, Alton K, Welte K, Souza L (1988) Effect of granulocyte colony-stimulating factor on neutropenia and associated morbidity due to chemotherapy for transitional-cell carcinoma of the urothelium. N Engl J Med 318:1414-1422
18. Geara F, Peters L, Ang K, Garden AS, Tucker SL, Levy LB, Brown BW (1996) Comparison between normal tissue reactions and local tumor control in head and neck cancer patients treated by definitive radiotherapy. Int J Radiat Oncol Biol Phys 35:455-462
19. Girdler NM, McGurk M, Aqual S, Prince M (1995) The effect of epidermal growth factor mouthwash on cytotoxi c-induced oral ulceration. Am J Clin Oncol 18:401-406
20. Gordon B, Spadinger A, Hodges E, Ruby E, Stanley R, Coccia P (1994) Effect of granulocyte-macrophage colony-stimulating factor on oral mucositis after hematopoietic stem-cell transplantation. J Clin Oncol 12:1917-1922
21. Hansen O, Overgaard J, Hansen HS, Overgaard M, Hoyer M, Jorgensen KE, Bastholt L, Berthelsen A (1997) Importance of overall treatment time for the outcome of radiotherapy of advanced head and neck carcinoma: dependency of tumor differentiation. Radiother Oncol 43:47-51
22. Horiot JC, Lefur R, N'Guyen T, Chenal C, Schraub S, Alfonsi S, Gardani G, Van den Bogaert S, Danczak S, Bolla M, Van Glabbeke M, de Pauw M (1992) Hyperfractionation versus conventional fractionation in oropharingeal carcicoma : Final analysis of a randomized trial of the EORTC cooperative group of radiotherapy. Radiother Oncol 25:231-241
23. Kaanders JH, Ang KK (1994) Early reactions and dose-limiting factor in radiotherapy. Semin Radiat Oncol 4:55-67
24. Kannan V, Bapsy PP, Anantha N, Doval DC, Vaithianathan H, Banumathy G, Reddy KB, Kuwaraswamy SV, Shenoy AM (1997) Efficacy and safety of granulocyte macrophage-colony stimulating factor (GM-CSF) on the frequency and severity of radiation mucositis in patients with head and neck carcinoma. Int J Radiat Oncol Biol Phys 37:1005-1010
25. Kubasova T, Horvath M, Kocsis K, Fenyo M (1995) Effect of visible light on some cellular and immune parameters. Immunol Cell Biol 73:239-244
26. Labar B, Mrsic M, Pavletic Z, Bogdanic V, Nemet D, Aurer I, Radman I, Sertic D, Kalenic S, Presecki V (1993) Prostaglandin E2 for prophylaxis of oral mucositis following BMT. Bone Marrow Transplant 11:379-382
27. Lieschke GJ, Ramenghi U, O'Connor MP, Sheridan W, Szer J, Morstyn G (1992) Studies of oral neutrophil levels in patients receiving G-CSF after autologous marrow transplantation. Br J Haematol 82:589-595
28. Meredith R, Salter M, Kim R, Spencer S, Weppelmann B, Rodu B, Smith J, Lee J (1997) Sucralfate for radiation mucositis : results of a double-blind randomized trial. Int J Radiat Oncol Biol Phys 13:275-279
29. Mose S, Adamietz IA, Saran F, Thilmann C, Heyd R, Knecht R, Böttcher HD (1997) Can prophylactic application of immunoglobulin decrease radiotherapy-induced oral mucositis. Am J Clin Oncol 20:407-411
30. Nishimura Y, Nagata Y, Okajima K, Mitsumori M, Hiraoka M, Masunaga S, Ono K, Shoji K, Kojima H (1996) Radiation therapy for T1,2 glottic carcinoma: impact of overall treatment time on local control. Radiother Oncol 40:225-232
31. Noble P, Shields E, Blecher P, Bentley K (1992) Locomotory characteristics of fibroblasts within a three-dimensional collagen matrice modulation by a He-Ne soft-laser. Laser Surg Med 12:669-674
32. Parsons JT (1994) The effect of radiation on normal tissues of head and neck. In: Million RR, Cassini NJ (eds) Management of head and neck cancer. A multidisciplinary approach, 2nd edn. Lippincott, Philadelphia, pp 245-247
33. Pourreau-Schneider N, Ahmed A, Soudry M, Jacquemier J, Kopp F, Franquin JC, Martin PM (1990) Helium-neon laser treatment transforms fibroblasts into myofibroblasts. Am J Pathol 137:171-178
34. Pourreau-Schneider N, Soudry M, Franquin J, Zattara H, Martin P, Ciais G, Namer M, Schneider M, Chauvel P, Demard F (1992) Soft-laser therapy for iatrogenic mucositis in cancer patients receiving high-dose fluorouracil: a preliminary report. J Natl Cancer Inst 84:358-359
35. Raber-Durlacher JE, Abraham L, Van Leevwen EF, Lustig KH, Van Winkelhof AJ (1989) The prevention of oral complications in bone marrow transplantations by means of oral hygiene and dental intervention. Neth J Med 34:98-108
36. Rovirosa A, Ferre J, Biete A (1998) Granulocyte macrophage-colony-stimulating factor mouthwashes heal oral ulcers during head and neck radiotherapy. Int J Radiat Oncol Biol Phys 41:747-754
37. Schubert MM (1993) Measurement of oral tissue damage and mucositis pain. In: Chapman CR, Foley KH (eds) Current and emerging issues in cancer pain: research and practice, chap 15. Raven Press, New York, pp 247-265
38. Schubert MM, Franquin JC, Niccoli-Filho F, Marcial F, Lloid M, Kelly J (1994) Effects of low-energy laser on oral mucositis : a phase I/Il pilot study. Cancer Researcher Weekly 7:14
39. Sheridan WP, Wolf M, Lusk J, Layton JE, Souza L, Morstyn G, Dodds A, Maher D, Green MD, Fox RM (1989) Granulocyte colony-stimulating factor and neutrophil recovery after high-dose chemotherapy and autologous bone marrow transplantation. Lancet II:891-895
40. Sixou JL, Medeiros-Batista O, Bonnaure-Mallet M (1996) Modifications of the microflora of the oral cavity arising during immunosuppresive chemotherapy. Eur J Cancer [B] 32 [Suppl] 306-310
41. Smichmidt-Ullrich RK, Johnson C, Wazer DE, Masko G, Chasin WD, Karmody CS (1991) Accelerated superfractionated irradiation for advanced carcinoma of head and neck Concomitant boost technique. Int J Radiat Oncol Biol Phys 21:563-568
42. Sonis ST (1998) Mucositis as a biological process: a new hypothesis for the development of chemotherapy-induced stomatotoxicity. Oral Oncol 34:39-43
43. Sonis ST, Van Vugt AG, BRien JPO, Muska AD, Bruskin AM, Rose A, Haley JD (1997) Transforming growth factor-B3 mediated modulation of cell cycling and attenuation of 5-fluorouracil induced oral mucositis. Oral Oncol 33:47-54
44. Soudry M, Franquin JC, Pourreau-Schneider N, Martin PM (1988) Action d'un laser helium-neon sur la croissance cellulaire : etude in vitro sur fibroblastes gingivaux humains. J Biol Buccale 16:129-135
45. Spijkervet FK, Van Saene HK, Vermey A, Mehta DM (1989) Scoring irradiation mucositis in head and neck cancer patients. J Oral Pathol 18:167-171
46. Symonds RP, McIlroy P, Khorrami J, Paul J, Pyper E, Alcock SR, McCallum I, Speekenbrink AB, McMurray A, Lindemann ETM (1996) The reduction of radiation mucositis by selective decontamination antibiotic pastilles: a placebo-controlled double-blind trial. Br J Cancer 74:312-317
47. Tardieu C, Cowen D, Thirion X, Franquin J.C Quantitative scale of oral mucositis associated with autologous bone marrow transplantation. (1996) Eur J Cancer [B] 32:381-387
48. Thyss A, Milano G, Renee N, Vallicioni J, Schneider M, Demard F (1986) Clinical pharmacokinetic study of 5-FU in continuous 5-day infusions for head and neck cancer. Cancer Chemother Pharmacol 16:64-66
49. Toljanic JA, Siddiqui AA, Patterson GL, Irwin ME (1996) An evaluation of a dentifrice containing salivary peroxidase elements for the control of gingival disease in patients with irradiated head and neck cancer. J Prosthet Dent 76:292-296
50. Tominaga R (1990) Effects of He-Ne laser irradiation on fibroblasts derived from scar tissue of rat palatal mucosa. J Stomatol Soc 57:580-594
51. Van den Bogaert WV, Van der Leest AV, Rijnders A, Delaere P, Thames H, Van der Shveren E (1995) Does tumor control decrease by prolonging overall treatment time or interrupting treatment in laryngeal carcinoma? Radiother Oncol 16:177-182
52. Verdi CJ, Garewal HS, Koenig ML, Vaughn B, Burkhead T (1995) A double blind, randomized, placebo-controlled, crossover trial of pentoxifylline for the prevention of chemotherapy-induced oral mucositis. Oral Surg Oral Med Oral Pathol 80:36-42