-
1
-
-
2942722533
-
A registry-based, case-control investigation of Parkinson's disease with and without cognitive impairment
-
Papapetropoulos S, Ellul J, Polychronopoulos P, Chroni E. A registry-based, case-control investigation of Parkinson's disease with and without cognitive impairment. Eur J Neurol 11:347-351, 2004.
-
(2004)
Eur J Neurol
, vol.11
, pp. 347-351
-
-
Papapetropoulos, S.1
Ellul, J.2
Polychronopoulos, P.3
Chroni, E.4
-
2
-
-
34447633928
-
Evolution of cognitive dysfunction in an incident Parkinson's disease cohort
-
Williams-Gray CH, Foltynie T, Brayne CE, Robbins TW, Barker RA. Evolution of cognitive dysfunction in an incident Parkinson's disease cohort. Brain 130:1787-1798, 2007.
-
(2007)
Brain
, vol.130
, pp. 1787-1798
-
-
Williams-Gray, C.H.1
Foltynie, T.2
Brayne, C.E.3
Robbins, T.W.4
Barker, R.A.5
-
3
-
-
3843080805
-
Mortality in Parkinson's disease and its association with dementia and depression
-
Hughes TA, Ross HF, Mindham RHS, Spokes EGS. Mortality in Parkinson's disease and its association with dementia and depression. Acta Neurol Scand 110:118-123, 2004.
-
(2004)
Acta Neurol Scand
, vol.110
, pp. 118-123
-
-
Hughes, T.A.1
Ross, H.F.2
Mindham, R.H.S.3
Spokes, E.G.S.4
-
4
-
-
0034037276
-
Cognitive impairment and the brain dopaminergic system in Parkinson disease: [18F]fluorodopa positron emission tomographic study
-
Rinne JO, Portin R, Ruottinen H, Nurmi E, Bergman J, Haaparanta M, Solin O. Cognitive impairment and the brain dopaminergic system in Parkinson disease: [18F]fluorodopa positron emission tomographic study. Arch Neurol 57:470-475, 2000.
-
(2000)
Arch Neurol
, vol.57
, pp. 470-475
-
-
Rinne, J.O.1
Portin, R.2
Ruottinen, H.3
Nurmi, E.4
Bergman, J.5
Haaparanta, M.6
Solin, O.7
-
5
-
-
13544255426
-
Cholinergic systems in progressive supranuclear palsy
-
Warren NM, Piggott MA, Perry EK, Burn DJ. Cholinergic systems in progressive supranuclear palsy. Brain 128:239-249, 2005.
-
(2005)
Brain
, vol.128
, pp. 239-249
-
-
Warren, N.M.1
Piggott, M.A.2
Perry, E.K.3
Burn, D.J.4
-
6
-
-
33847714701
-
A magnetic resonance imaging study of patients with Parkinson's disease with mild cognitive impairment and dementia using voxel-based morphometry
-
Beyer MK, Janvin CC, Larsen JP, Aarsland D. A magnetic resonance imaging study of patients with Parkinson's disease with mild cognitive impairment and dementia using voxel-based morphometry. J Neurol Neurosurg Psychiatry 78:254-259, 2007.
-
(2007)
J Neurol Neurosurg Psychiatry
, vol.78
, pp. 254-259
-
-
Beyer, M.K.1
Janvin, C.C.2
Larsen, J.P.3
Aarsland, D.4
-
7
-
-
22144498494
-
Relationship between Parkinson disease with dementia and dementia with Lewy bodies
-
Guo L, Itaya M, Takanashi M, Mizuno Y, Mori H. Relationship between Parkinson disease with dementia and dementia with Lewy bodies. Parkinsonism Relat Disord 11:305-309, 2005.
-
(2005)
Parkinsonism Relat Disord
, vol.11
, pp. 305-309
-
-
Guo, L.1
Itaya, M.2
Takanashi, M.3
Mizuno, Y.4
Mori, H.5
-
8
-
-
33846997878
-
Presynaptic alpha-synuclein aggregates, not Lewy bodies, cause neurodegeneration in dementia with Lewy bodies
-
Kramer ML, Schulz-Schaeffer WJ. Presynaptic alpha-synuclein aggregates, not Lewy bodies, cause neurodegeneration in dementia with Lewy bodies. J Neurosci 27:1405-1410, 2007.
-
(2007)
J Neurosci
, vol.27
, pp. 1405-1410
-
-
Kramer, M.L.1
Schulz-Schaeffer, W.J.2
-
9
-
-
0141638380
-
3,4- Dihydroxyphenylacetaldehyde is the toxic dopamine metabolite in vivo: Implications for Parkinson's disease pathogenesis
-
Burke WJ, Li SW, Williams EA, Nonneman R, Zahm DS. 3,4- Dihydroxyphenylacetaldehyde is the toxic dopamine metabolite in vivo: implications for Parkinson's disease pathogenesis. Brain Res 989:205-213, 2003.
-
(2003)
Brain Res
, vol.989
, pp. 205-213
-
-
Burke, W.J.1
Li, S.W.2
Williams, E.A.3
Nonneman, R.4
Zahm, D.S.5
-
10
-
-
34548172773
-
Different species of alpha-synuclein oligomers induce calcium influx and seeding
-
Danzer KM, Haasen D, Karow AR, Moussaud S, Habeck M, Giese A, Kretzschmar H, Hengerer B, and Kostka M. Different species of alpha-synuclein oligomers induce calcium influx and seeding. J Neurosci 27:9220-9232, 2007.
-
(2007)
J Neurosci
, vol.27
, pp. 9220-9232
-
-
Danzer, K.M.1
Haasen, D.2
Karow, A.R.3
Moussaud, S.4
Habeck, M.5
Giese, A.6
Kretzschmar, H.7
Hengerer, B.8
Kostka, M.9
-
11
-
-
4644277646
-
Hippocampal and prefrontal atrophy in patients with early non-demented Parkinson's disease is related to cognitive impairment
-
Bruck A, Kurki T, Kaasinen V, Vahlberg T, Rinne JO. Hippocampal and prefrontal atrophy in patients with early non-demented Parkinson's disease is related to cognitive impairment. J Neurol, Neurosurg Psychiatry 75:1467-1469, 2004.
-
(2004)
J Neurol, Neurosurg Psychiatry
, vol.75
, pp. 1467-1469
-
-
Bruck, A.1
Kurki, T.2
Kaasinen, V.3
Vahlberg, T.4
Rinne, J.O.5
-
12
-
-
34249826098
-
Action and object naming in Parkinson's disease without dementia
-
Cotelli M, Borroni B, Manenti R, Zanetti M, Arevalo A, Cappa SF, Padovani A. Action and object naming in Parkinson's disease without dementia. Eur J Neurol 14:632-637, 2007.
-
(2007)
Eur J Neurol
, vol.14
, pp. 632-637
-
-
Cotelli, M.1
Borroni, B.2
Manenti, R.3
Zanetti, M.4
Arevalo, A.5
Cappa, S.F.6
Padovani, A.7
-
13
-
-
32544457835
-
The dopaminergic midbrain participates in human episodic memory formation: Evidence from genetic imaging
-
Schott BH, Seidenbecher CI, Fenker DB, Lauer CJ, Bunzeck N, Bernstein HG, Tischmeyer W, Gundelfinger ED, Heinze HJ, Duzel E. The dopaminergic midbrain participates in human episodic memory formation: evidence from genetic imaging. J Neurosci 26:1407-1417, 2006.
-
(2006)
J Neurosci
, vol.26
, pp. 1407-1417
-
-
Schott, B.H.1
Seidenbecher, C.I.2
Fenker, D.B.3
Lauer, C.J.4
Bunzeck, N.5
Bernstein, H.G.6
Tischmeyer, W.7
Gundelfinger, E.D.8
Heinze, H.J.9
Duzel, E.10
-
14
-
-
34247387212
-
Tolcapone improves cognition and cortical information processing in normal human subjects
-
Apud JA, Mattay V, Chen J, Kolachana BS, Callicott JH, Rasetti R, Alce G, Iudicello JE, Akbar N, Egan MF, Goldberg TE, Weinberger DR. Tolcapone improves cognition and cortical information processing in normal human subjects. Neuropsychopharmacology 32:1011-1020, 2007.
-
(2007)
Neuropsychopharmacology
, vol.32
, pp. 1011-1020
-
-
Apud, J.A.1
Mattay, V.2
Chen, J.3
Kolachana, B.S.4
Callicott, J.H.5
Rasetti, R.6
Alce, G.7
Iudicello, J.E.8
Akbar, N.9
Egan, M.F.10
Goldberg, T.E.11
Weinberger, D.R.12
-
15
-
-
10044283107
-
Rivastigmine for dementia associated with Parkinson's disease
-
Emre M, Aarsland D, Albanese A, Byrne EJ, Deuschl G, De Deyn PP, Durif F, Kulisevsky J, van Laar T, Lees A, Poewe W, Robillard A, Rosa MM, Wolters E, Quarg P, Tekin S, Lane R. Rivastigmine for dementia associated with Parkinson's disease. N Engl J Med 351:2509-2518, 2004.
-
(2004)
N Engl J Med
, vol.351
, pp. 2509-2518
-
-
Emre, M.1
Aarsland, D.2
Albanese, A.3
Byrne, E.J.4
Deuschl, G.5
De Deyn, P.P.6
Durif, F.7
Kulisevsky, J.8
van Laar, T.9
Lees, A.10
Poewe, W.11
Robillard, A.12
Rosa, M.M.13
Wolters, E.14
Quarg, P.15
Tekin, S.16
Lane, R.17
-
16
-
-
0842325101
-
Randomized placebo-controlled trial of donepezil in cognitive impairment in Parkinson's disease
-
Leroi I, Brandt J, Reich SG, Lyketsos CG, Grill S, Thompson R, Marsh L. Randomized placebo-controlled trial of donepezil in cognitive impairment in Parkinson's disease. Int J Geriatr Psychiatry 19:1-8, 2004.
-
(2004)
Int J Geriatr Psychiatry
, vol.19
, pp. 1-8
-
-
Leroi, I.1
Brandt, J.2
Reich, S.G.3
Lyketsos, C.G.4
Grill, S.5
Thompson, R.6
Marsh, L.7
-
17
-
-
0348109448
-
Pharmacologic treatment expectations in the management of dementia with Lewy bodies
-
Kaufer DI. Pharmacologic treatment expectations in the management of dementia with Lewy bodies. Dement Geriatr Cogn Disord 17(Suppl 1): 32-39, 2004.
-
(2004)
Dement Geriatr Cogn Disord
, vol.17
, Issue.SUPPL. 1
, pp. 32-39
-
-
Kaufer, D.I.1
-
18
-
-
33646716916
-
Donepezil effects on cerebral blood flow in older adults with mild cognitive deficits
-
Chen X, Magnotta VA, Duff K, Boles Ponto LL, Schultz SK. Donepezil effects on cerebral blood flow in older adults with mild cognitive deficits. J Neuropsychiatry Clin Neurosci 18:178-185, 2006.
-
(2006)
J Neuropsychiatry Clin Neurosci
, vol.18
, pp. 178-185
-
-
Chen, X.1
Magnotta, V.A.2
Duff, K.3
Boles Ponto, L.L.4
Schultz, S.K.5
-
19
-
-
3242762403
-
Pharmacological aspects of (-)-deprenyl
-
Magyar K, Palfi M, Tabi T, Kalasz H, Szende B, Szoko E. Pharmacological aspects of (-)-deprenyl. Curr Med Chem 11:2017-2031, 2004.
-
(2004)
Curr Med Chem
, vol.11
, pp. 2017-2031
-
-
Magyar, K.1
Palfi, M.2
Tabi, T.3
Kalasz, H.4
Szende, B.5
Szoko, E.6
-
20
-
-
0027496801
-
Selegiline can mediate neuronal rescue rather than neuronal protection
-
Tatton WG. Selegiline can mediate neuronal rescue rather than neuronal protection. Mov Disord 8:S20-S30, 1993.
-
(1993)
Mov Disord
, vol.8
-
-
Tatton, W.G.1
-
21
-
-
32844455973
-
Chronic exposure of rats to cognition enhancing drugs produces a neuroplastic response identical to that obtained by complex environment rearing
-
Murphy KJ, Foley AG, O'Connell AW, Regan CM. Chronic exposure of rats to cognition enhancing drugs produces a neuroplastic response identical to that obtained by complex environment rearing. Neuro-psychopharmacology 31:90-100, 2006.
-
(2006)
Neuro-psychopharmacology
, vol.31
, pp. 90-100
-
-
Murphy, K.J.1
Foley, A.G.2
O'Connell, A.W.3
Regan, C.M.4
-
22
-
-
34748825072
-
-
Schifitto G, Zhang J, Evans SR, Sacktor N, Simpson D, Millar LL, Hung VL, Miller EN, Smith E, Ellis RJ, Valcour V, Singer E, Marra CM, Kolson D, Weihe J, Remmel R, Katzenstein D, Clifford DB; ACTG A5090 Team. A multicenter trial of selegiline transdermal system for HIV-associated cognitive impairment. Neurology 69:1314-1321, 2007.
-
Schifitto G, Zhang J, Evans SR, Sacktor N, Simpson D, Millar LL, Hung VL, Miller EN, Smith E, Ellis RJ, Valcour V, Singer E, Marra CM, Kolson D, Weihe J, Remmel R, Katzenstein D, Clifford DB; ACTG A5090 Team. A multicenter trial of selegiline transdermal system for HIV-associated cognitive impairment. Neurology 69:1314-1321, 2007.
-
-
-
-
23
-
-
0037012478
-
Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa on Parkinson disease progression
-
Parkinson Study Group
-
Parkinson Study Group. Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa on Parkinson disease progression. JAMA 287:1653-1661, 2002.
-
(2002)
JAMA
, vol.287
, pp. 1653-1661
-
-
-
24
-
-
28744439018
-
Dopamine D3 receptor-preferring agonists induce neurotrophic effects on mesencephalic dopamine neurons
-
Du F, Li R, Huang Y, Li X, Le W. Dopamine D3 receptor-preferring agonists induce neurotrophic effects on mesencephalic dopamine neurons. Eur J Neurosci 22:2422-2430, 2005.
-
(2005)
Eur J Neurosci
, vol.22
, pp. 2422-2430
-
-
Du, F.1
Li, R.2
Huang, Y.3
Li, X.4
Le, W.5
-
25
-
-
0034856154
-
Randomized study of the dopamine receptor agonist piribedil in the treatment of mild cognitive impairment
-
Nagaraja D, Jayashree S. Randomized study of the dopamine receptor agonist piribedil in the treatment of mild cognitive impairment. Am J Psychiatry 158:1517-1519, 2001.
-
(2001)
Am J Psychiatry
, vol.158
, pp. 1517-1519
-
-
Nagaraja, D.1
Jayashree, S.2
-
26
-
-
33751181268
-
The dopamine agonist piribedil with L-DOPA improves attentional dysfunction: Relevance for Parkinson's disease
-
Turle-Lorenzo N, Maurin B, Puma C, Chezaubernard C, Morain P, Baunez C, Nieoullon A, Amalric M. The dopamine agonist piribedil with L-DOPA improves attentional dysfunction: relevance for Parkinson's disease. J Pharmacol Exp Ther 319:914-923, 2006.
-
(2006)
J Pharmacol Exp Ther
, vol.319
, pp. 914-923
-
-
Turle-Lorenzo, N.1
Maurin, B.2
Puma, C.3
Chezaubernard, C.4
Morain, P.5
Baunez, C.6
Nieoullon, A.7
Amalric, M.8
-
27
-
-
0037382089
-
Piribedil enhances frontocortical and hippocampal release of acetylcholine in freely moving rats by blockade of alpha 2A-adrenoceptors: A dialysis comparison to talipexole and quinelorane in the absence of acetylcholinesterase inhibitors
-
Gobert A, Di Cara B, Cistarelli L, Millan MJ. Piribedil enhances frontocortical and hippocampal release of acetylcholine in freely moving rats by blockade of alpha 2A-adrenoceptors: a dialysis comparison to talipexole and quinelorane in the absence of acetylcholinesterase inhibitors. J Pharmacol Exp Ther 305:338-346, 2003.
-
(2003)
J Pharmacol Exp Ther
, vol.305
, pp. 338-346
-
-
Gobert, A.1
Di Cara, B.2
Cistarelli, L.3
Millan, M.J.4
-
28
-
-
3042567248
-
Memantine can relieve certain symptoms in Parkinson disease. Improvement achieved in two out of three described cases with dyskinesia and cognitive failure]
-
Lokk J. [Memantine can relieve certain symptoms in Parkinson disease. Improvement achieved in two out of three described cases with dyskinesia and cognitive failure]. Lakartidningen 101:2003-2006, 2004.
-
(2004)
Lakartidningen
, vol.101
, pp. 2003-2006
-
-
Lokk, J.1
-
29
-
-
33750813865
-
In vitro galantamine-memantine co-application: Mechanism of beneficial action
-
Zhao X, Marszalec W, Toth PT, Huang J, Yeh JZ, Narahashi T. In vitro galantamine-memantine co-application: mechanism of beneficial action. Neuropharmacology 51:1181-1191, 2006.
-
(2006)
Neuropharmacology
, vol.51
, pp. 1181-1191
-
-
Zhao, X.1
Marszalec, W.2
Toth, P.T.3
Huang, J.4
Yeh, J.Z.5
Narahashi, T.6
-
30
-
-
1442300051
-
Effect of riluzole on dyskinesia and duration of the on state in Parkinson disease patients: A double-blind, placebo-controlled pilot study
-
Braz CA, Borges V, Ferraz HB. Effect of riluzole on dyskinesia and duration of the on state in Parkinson disease patients: a double-blind, placebo-controlled pilot study. Clin Neuropharmacol 27:25-29, 2004.
-
(2004)
Clin Neuropharmacol
, vol.27
, pp. 25-29
-
-
Braz, C.A.1
Borges, V.2
Ferraz, H.B.3
-
31
-
-
33750345592
-
Glutamate release inhibition ineffective in levodopa-induced motor complications
-
Bara-Jimenez W, Dimitrova TD, Sherzai A, Aksu M, Chase TN. Glutamate release inhibition ineffective in levodopa-induced motor complications. Mov Disord 21:1380-1383, 2006.
-
(2006)
Mov Disord
, vol.21
, pp. 1380-1383
-
-
Bara-Jimenez, W.1
Dimitrova, T.D.2
Sherzai, A.3
Aksu, M.4
Chase, T.N.5
-
32
-
-
33748767364
-
Acceleration of amyloid beta-peptide aggregation by physiological concentrations of calcium
-
Isaacs AM, Senn DB, Yuan M, Shine JP, Yankner BA. Acceleration of amyloid beta-peptide aggregation by physiological concentrations of calcium. J Biol Chem 281:27916-27923, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 27916-27923
-
-
Isaacs, A.M.1
Senn, D.B.2
Yuan, M.3
Shine, J.P.4
Yankner, B.A.5
-
33
-
-
20744442879
-
Effects of the dopaminergic agent and NMDA receptor antagonist amantadine on cognitive function, cerebral glucose metabolism and D2 receptor availability in chronic traumatic brain injury: A study using positron emission tomography (PET)
-
Kraus MF, Smith GS, Butters M, Donnell AJ, Dixon E, Yilong C, Marion D. Effects of the dopaminergic agent and NMDA receptor antagonist amantadine on cognitive function, cerebral glucose metabolism and D2 receptor availability in chronic traumatic brain injury: a study using positron emission tomography (PET). Brain Inj 19:471-479, 2005.
-
(2005)
Brain Inj
, vol.19
, pp. 471-479
-
-
Kraus, M.F.1
Smith, G.S.2
Butters, M.3
Donnell, A.J.4
Dixon, E.5
Yilong, C.6
Marion, D.7
-
34
-
-
33750290651
-
Association between amantadine and the onset of dementia in Parkinson's disease
-
Inzelberg R, Bonuccelli U, Schechtman E, Miniowich A, Strugatsky R, Ceravolo R, Logi C, Rossi C, Klein C, Rabey JM. Association between amantadine and the onset of dementia in Parkinson's disease. Mov Disord 21:1375-1379, 2006.
-
(2006)
Mov Disord
, vol.21
, pp. 1375-1379
-
-
Inzelberg, R.1
Bonuccelli, U.2
Schechtman, E.3
Miniowich, A.4
Strugatsky, R.5
Ceravolo, R.6
Logi, C.7
Rossi, C.8
Klein, C.9
Rabey, J.M.10
-
35
-
-
0029884473
-
Amantadine treatment is an independent predictor of improved survival in Parkinson's disease
-
Uitti RJ, Rajput AH, Ahlskog JE, Offord KP, Schroeder DR, Ho MM, Prasad M, Rajput A, Basran P. Amantadine treatment is an independent predictor of improved survival in Parkinson's disease. Neurology 46: 1551-1556, 1996.
-
(1996)
Neurology
, vol.46
, pp. 1551-1556
-
-
Uitti, R.J.1
Rajput, A.H.2
Ahlskog, J.E.3
Offord, K.P.4
Schroeder, D.R.5
Ho, M.M.6
Prasad, M.7
Rajput, A.8
Basran, P.9
-
37
-
-
12944305793
-
Neuromelanin biosynthesis is driven by excess cytosolic catechol-amines not accumulated by synaptic vesicles
-
Sulzer D, Bogulavsky J, Larsen KE, Behr G, Karatekin E, Kleinman MH, Turro N, Krantz D, Edwards RH, Greene LA, Zecca L. Neuromelanin biosynthesis is driven by excess cytosolic catechol-amines not accumulated by synaptic vesicles. Proc Natl Acad Sci U S A 97:11869-11874, 2000.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 11869-11874
-
-
Sulzer, D.1
Bogulavsky, J.2
Larsen, K.E.3
Behr, G.4
Karatekin, E.5
Kleinman, M.H.6
Turro, N.7
Krantz, D.8
Edwards, R.H.9
Greene, L.A.10
Zecca, L.11
-
38
-
-
0032744787
-
High doses of vitamin E in the treatment of disorders of the central nervous system in the aged
-
Vatassery GT, Bauer T, Dysken M. High doses of vitamin E in the treatment of disorders of the central nervous system in the aged. Am J Clin Nutr 70:793-801, 1999.
-
(1999)
Am J Clin Nutr
, vol.70
, pp. 793-801
-
-
Vatassery, G.T.1
Bauer, T.2
Dysken, M.3
-
39
-
-
34447252358
-
-
Storch A, Jost WH, Vieregge P, Spiegel J, Greulich W, Durner J, Muller T, Kupsch A, Henningsen H, Oertel WH, Fuchs G, Kuhn W, Niklowitz P, Koch R, Herting B, Reichmann H; for the German Coenzyme Q10 Study Group. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 64:938-944, 2007.
-
Storch A, Jost WH, Vieregge P, Spiegel J, Greulich W, Durner J, Muller T, Kupsch A, Henningsen H, Oertel WH, Fuchs G, Kuhn W, Niklowitz P, Koch R, Herting B, Reichmann H; for the German Coenzyme Q10 Study Group. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 64:938-944, 2007.
-
-
-
-
40
-
-
0041653249
-
Nonsteroidal anti-inflammatory drugs and the risk of Parkinson disease
-
Chen H, Zhang SM, Hernan MA, Schwarzschild MA, Willett WC, Colditz GA, Speizer FE, Ascherio A. Nonsteroidal anti-inflammatory drugs and the risk of Parkinson disease. Arch Neurol 60:1059-1064, 2003.
-
(2003)
Arch Neurol
, vol.60
, pp. 1059-1064
-
-
Chen, H.1
Zhang, S.M.2
Hernan, M.A.3
Schwarzschild, M.A.4
Willett, W.C.5
Colditz, G.A.6
Speizer, F.E.7
Ascherio, A.8
-
41
-
-
34249293021
-
Low dose aspirin and cognitive function in the women's health study cognitive cohort
-
Kang JH, Cook N, Manson J, Buring JE, Grodstein F. Low dose aspirin and cognitive function in the women's health study cognitive cohort. BMJ 334:987-994, 2007.
-
(2007)
BMJ
, vol.334
, pp. 987-994
-
-
Kang, J.H.1
Cook, N.2
Manson, J.3
Buring, J.E.4
Grodstein, F.5
-
42
-
-
21144447586
-
Rofecoxib Protocol 078 Study Group. A randomized, double-blind, study of rofecoxib in patients with mild cognitive impairment
-
Thal LJ, Ferris SH, Kirby L, Block GA, Lines CR, Yuen E, Assaid C, Nessly ML, Norman BA, Baranak CC, Reines SA; Rofecoxib Protocol 078 Study Group. A randomized, double-blind, study of rofecoxib in patients with mild cognitive impairment. Neuropsychopharmacology 30:1204-1215, 2005.
-
(2005)
Neuropsychopharmacology
, vol.30
, pp. 1204-1215
-
-
Thal, L.J.1
Ferris, S.H.2
Kirby, L.3
Block, G.A.4
Lines, C.R.5
Yuen, E.6
Assaid, C.7
Nessly, M.L.8
Norman, B.A.9
Baranak, C.C.10
Reines, S.A.11
-
43
-
-
34548249144
-
Ageing and early-stage Parkinson's disease affect separable neural mechanisms of mesolimbic reward processing
-
Schott BH, Niehaus L, Wittmann BC, Schütze H, Seidenbecher CI, Heinze HJ, Düzel E. Ageing and early-stage Parkinson's disease affect separable neural mechanisms of mesolimbic reward processing. Brain 130:2412-2424, 2007.
-
(2007)
Brain
, vol.130
, pp. 2412-2424
-
-
Schott, B.H.1
Niehaus, L.2
Wittmann, B.C.3
Schütze, H.4
Seidenbecher, C.I.5
Heinze, H.J.6
Düzel, E.7
-
44
-
-
0036158587
-
Attention to action in Parkinson's disease: Impaired effective connectivity among frontal cortical regions
-
Rowe J, Stephan KE, Friston K, Frackowiak R, Lees A, Passingham R. Attention to action in Parkinson's disease: impaired effective connectivity among frontal cortical regions. Brain 125:276-289, 2002.
-
(2002)
Brain
, vol.125
, pp. 276-289
-
-
Rowe, J.1
Stephan, K.E.2
Friston, K.3
Frackowiak, R.4
Lees, A.5
Passingham, R.6
-
45
-
-
0036154591
-
Dopaminergic modulation of cortical function in patients with Parkinson's disease
-
Mattay VS, Tessitore A, Callicott JH, Bertolino A, Goldberg TE, Chase TN, Hyde TM, Weinberger DR. Dopaminergic modulation of cortical function in patients with Parkinson's disease. Ann Neurol 51:156-164, 2002.
-
(2002)
Ann Neurol
, vol.51
, pp. 156-164
-
-
Mattay, V.S.1
Tessitore, A.2
Callicott, J.H.3
Bertolino, A.4
Goldberg, T.E.5
Chase, T.N.6
Hyde, T.M.7
Weinberger, D.R.8
-
46
-
-
34548165783
-
Safety and tolerability of adjunctive Tolcapone therapy in early Parkinson's disease patients
-
Lees AJ, Ratziu V, Tolosa E, Oertel WH. Safety and tolerability of adjunctive Tolcapone therapy in early Parkinson's disease patients. J Neurol Neurosurg Psychiatry 78:944-948, 2007.
-
(2007)
J Neurol Neurosurg Psychiatry
, vol.78
, pp. 944-948
-
-
Lees, A.J.1
Ratziu, V.2
Tolosa, E.3
Oertel, W.H.4
-
47
-
-
0036939547
-
Positive modulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate receptors elicits neuroprotection after trimethyltin exposure in hippocampus
-
Munirathinam S, Rogers G, Bahr BA. Positive modulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate receptors elicits neuroprotection after trimethyltin exposure in hippocampus. Toxicol Appl Pharmacol 185:111-118, 2002.
-
(2002)
Toxicol Appl Pharmacol
, vol.185
, pp. 111-118
-
-
Munirathinam, S.1
Rogers, G.2
Bahr, B.A.3
-
48
-
-
34249098796
-
AMPA receptor potentiators: Application for depression and Parkinson's disease
-
O'Neill MJ, Witkin JM. AMPA receptor potentiators: application for depression and Parkinson's disease. Curr Drug Targets 8:603-620, 2007.
-
(2007)
Curr Drug Targets
, vol.8
, pp. 603-620
-
-
O'Neill, M.J.1
Witkin, J.M.2
-
49
-
-
34249079802
-
Acute effects of the ampakine farampator on memory and information processing in healthy elderly volunteers
-
Wezenberg E, Verkes RJ, Ruigt GS, Hulstijn W, Sabbe BG. Acute effects of the ampakine farampator on memory and information processing in healthy elderly volunteers. Neuropsychopharmacology 32:1272-1283, 2007.
-
(2007)
Neuropsychopharmacology
, vol.32
, pp. 1272-1283
-
-
Wezenberg, E.1
Verkes, R.J.2
Ruigt, G.S.3
Hulstijn, W.4
Sabbe, B.G.5
-
50
-
-
0031893241
-
Mortality in DATATOP: A multicenter trial in early Parkinson's disease
-
Parkinson Study Group
-
Parkinson Study Group. Mortality in DATATOP: a multicenter trial in early Parkinson's disease. Ann Neurol 43:318-325, 1998.
-
(1998)
Ann Neurol
, vol.43
, pp. 318-325
-
-
-
51
-
-
33744980931
-
Rationale for considering that propargylamines might be neuroprotective in Parkinson's disease
-
Olanow CW. Rationale for considering that propargylamines might be neuroprotective in Parkinson's disease. Neurology 66(Suppl 4):S69-S79, 2006.
-
(2006)
Neurology
, vol.66
, Issue.SUPPL. 4
-
-
Olanow, C.W.1
-
52
-
-
0030612117
-
Coenzyme Q10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects
-
Shults CW, Haas RH, Passov D, Beal MF. Coenzyme Q10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects. Ann Neurol 42:261-264, 1997.
-
(1997)
Ann Neurol
, vol.42
, pp. 261-264
-
-
Shults, C.W.1
Haas, R.H.2
Passov, D.3
Beal, M.F.4
-
53
-
-
0036771852
-
Parkinson Study Group. Effects of coenzyme Q10 in early Parkinson disease: Evidence of slowing of the functional decline
-
Shults CW, Oakes D, Kieburtz K, Beal MF, Haas R, Plumb S, Juncos JL, Nutt J, Shoulson I, Carter J, Kompoliti K, Perlmutter JS, Reich S, Stern M, Watts RL, Kurlan R, Molho E, Harrison M, Lew M; Parkinson Study Group. Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline. Arch Neurol 59:1541-1550, 2002.
-
(2002)
Arch Neurol
, vol.59
, pp. 1541-1550
-
-
Shults, C.W.1
Oakes, D.2
Kieburtz, K.3
Beal, M.F.4
Haas, R.5
Plumb, S.6
Juncos, J.L.7
Nutt, J.8
Shoulson, I.9
Carter, J.10
Kompoliti, K.11
Perlmutter, J.S.12
Reich, S.13
Stern, M.14
Watts, R.L.15
Kurlan, R.16
Molho, E.17
Harrison, M.18
Lew, M.19
-
54
-
-
0037176885
-
Neuroprotection and dopamine agonists
-
Schapira AH. Neuroprotection and dopamine agonists. Neurology 58: S9-S18, 2002.
-
(2002)
Neurology
, vol.58
-
-
Schapira, A.H.1
-
55
-
-
0033554203
-
Dopamine D2 receptor-mediated antioxidant and neuroprotective effects of ropinirole, a dopamine agonist
-
Iida M, Miyazaki I, Tanaka K, Kabuto H, Iwata-Ichikawa E, Ogawa N. Dopamine D2 receptor-mediated antioxidant and neuroprotective effects of ropinirole, a dopamine agonist. Brain Res 838:51-59, 1999.
-
(1999)
Brain Res
, vol.838
, pp. 51-59
-
-
Iida, M.1
Miyazaki, I.2
Tanaka, K.3
Kabuto, H.4
Iwata-Ichikawa, E.5
Ogawa, N.6
-
56
-
-
0037785449
-
REAL-PET Study Group. Slower progression of Parkinson's disease with ropinirole versus levodopa: The REAL-PET study
-
Whone AL, Watts RL, Stoessl AJ, Davis M, Reske S, Nahmias C, Lang AE, Rascol O, Ribeiro MJ, Remy P, Poewe WH, Hauser RA, Brooks DJ; REAL-PET Study Group. Slower progression of Parkinson's disease with ropinirole versus levodopa: the REAL-PET study. Ann Neurol 54:93-101, 2003.
-
(2003)
Ann Neurol
, vol.54
, pp. 93-101
-
-
Whone, A.L.1
Watts, R.L.2
Stoessl, A.J.3
Davis, M.4
Reske, S.5
Nahmias, C.6
Lang, A.E.7
Rascol, O.8
Ribeiro, M.J.9
Remy, P.10
Poewe, W.H.11
Hauser, R.A.12
Brooks, D.J.13
-
57
-
-
3142733662
-
Pramipexole vs levodopa as initial treatment for Parkinson disease: A 4-year randomized controlled trial
-
Parkinson Study Group
-
Parkinson Study Group. Pramipexole vs levodopa as initial treatment for Parkinson disease: a 4-year randomized controlled trial. Arch Neurol 61:1044-1053, 2004.
-
(2004)
Arch Neurol
, vol.61
, pp. 1044-1053
-
-
-
58
-
-
34347225955
-
Long-term cognitive profile and incidence of dementia after STN-DBS in Parkinson's disease
-
Aybek S, Gronchi-Perrin A, Berney A, Chiuve SC, Villemure JG, Burkhard PR, Vingerhoets FJ. Long-term cognitive profile and incidence of dementia after STN-DBS in Parkinson's disease. Mov Disord 22:S974-S981, 2007.
-
(2007)
Mov Disord
, vol.22
-
-
Aybek, S.1
Gronchi-Perrin, A.2
Berney, A.3
Chiuve, S.C.4
Villemure, J.G.5
Burkhard, P.R.6
Vingerhoets, F.J.7
-
59
-
-
33847713338
-
Cognitive outcome 5 years after bilateral chronic stimulation of subthalamic nucleus in patients with Parkinson's disease
-
Contarino MF, Daniele A, Sibilia AH, Romito LM, Bentivoglio AR, Gainotti G, Albanese A. Cognitive outcome 5 years after bilateral chronic stimulation of subthalamic nucleus in patients with Parkinson's disease. J Neurol Neurosurg Psychiatry 78:248-252, 2007.
-
(2007)
J Neurol Neurosurg Psychiatry
, vol.78
, pp. 248-252
-
-
Contarino, M.F.1
Daniele, A.2
Sibilia, A.H.3
Romito, L.M.4
Bentivoglio, A.R.5
Gainotti, G.6
Albanese, A.7
-
60
-
-
33846919884
-
Concise review: Therapeutic strategies for Parkinson disease based on the modulation of adult neurogenesis
-
Geraerts M, Krylyshkina O, Debyser Z, Baekelandt V. Concise review: therapeutic strategies for Parkinson disease based on the modulation of adult neurogenesis. Stem Cells 25:263-270, 2007.
-
(2007)
Stem Cells
, vol.25
, pp. 263-270
-
-
Geraerts, M.1
Krylyshkina, O.2
Debyser, Z.3
Baekelandt, V.4
-
61
-
-
3042822087
-
Dopamine depletion impairs precursor cell proliferation in Parkinson disease
-
Höglinger GU, Rizk P, Muriel MP, Duyckaerts C, Oertel WH, Caille I, Hirsch EC. Dopamine depletion impairs precursor cell proliferation in Parkinson disease. Nat Neurosci 7:726-735, 2004.
-
(2004)
Nat Neurosci
, vol.7
, pp. 726-735
-
-
Höglinger, G.U.1
Rizk, P.2
Muriel, M.P.3
Duyckaerts, C.4
Oertel, W.H.5
Caille, I.6
Hirsch, E.C.7
-
62
-
-
0035087826
-
Immortalized multipotential mesenchymal cells and the hematopoietic microenvironment
-
Dormady SP, Bashayan O, Dougherty R, Zhang XM, Basch RS. Immortalized multipotential mesenchymal cells and the hematopoietic microenvironment. J Hematother Stem Cell Res 10:125-140, 2001.
-
(2001)
J Hematother Stem Cell Res
, vol.10
, pp. 125-140
-
-
Dormady, S.P.1
Bashayan, O.2
Dougherty, R.3
Zhang, X.M.4
Basch, R.S.5
-
63
-
-
0038787488
-
Marrow stromal cells, mitosis, and neuronal differentiation: Stem cell and precursor functions
-
Munoz-Elias G, Woodbury D, Black IB. Marrow stromal cells, mitosis, and neuronal differentiation: stem cell and precursor functions. Stem Cells 21:437-448, 2003.
-
(2003)
Stem Cells
, vol.21
, pp. 437-448
-
-
Munoz-Elias, G.1
Woodbury, D.2
Black, I.B.3
-
64
-
-
34648860537
-
Bone marrow-derived mesenchymal stromal cells for the repair of central nervous system injury
-
Parr AM, Tator CH, Keating A. Bone marrow-derived mesenchymal stromal cells for the repair of central nervous system injury. Bone Marrow Transplantation 40:609-619, 2007.
-
(2007)
Bone Marrow Transplantation
, vol.40
, pp. 609-619
-
-
Parr, A.M.1
Tator, C.H.2
Keating, A.3
-
65
-
-
33947515418
-
Involvement of interferon-gamma in microglial-mediated loss of dopaminergic neurons
-
Mount MP, Lira A, Grimes D, Smith PD, Faucher S, Slack R, Anisman H, Hayley S, Park DS. Involvement of interferon-gamma in microglial-mediated loss of dopaminergic neurons. J Neurosci 27:3328-3337, 2007.
-
(2007)
J Neurosci
, vol.27
, pp. 3328-3337
-
-
Mount, M.P.1
Lira, A.2
Grimes, D.3
Smith, P.D.4
Faucher, S.5
Slack, R.6
Anisman, H.7
Hayley, S.8
Park, D.S.9
-
66
-
-
33847198228
-
Subthalamic glutamic acid decarboxylase gene therapy: Changes in motor function and cortical metabolism
-
Emborg ME, Carbon M, Holden JE, During MJ, Ma Y, Tang C, Moirano J, Fitzsimons H, Roitberg BZ, Tuccar E, Roberts A, Kaplitt MG, Eidelberg D. Subthalamic glutamic acid decarboxylase gene therapy: changes in motor function and cortical metabolism. J Cereb Blood Flow Metab 27:501-509, 2007.
-
(2007)
J Cereb Blood Flow Metab
, vol.27
, pp. 501-509
-
-
Emborg, M.E.1
Carbon, M.2
Holden, J.E.3
During, M.J.4
Ma, Y.5
Tang, C.6
Moirano, J.7
Fitzsimons, H.8
Roitberg, B.Z.9
Tuccar, E.10
Roberts, A.11
Kaplitt, M.G.12
Eidelberg, D.13
-
67
-
-
33845993229
-
Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP-treated monkeys
-
Kordower JH, Herzog CD, Dass B, Bakay RA, Stansell J 3rd, Gasmi M, Bartus RT. Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP-treated monkeys. Ann Neurol 60:706-715, 2006.
-
(2006)
Ann Neurol
, vol.60
, pp. 706-715
-
-
Kordower, J.H.1
Herzog, C.D.2
Dass, B.3
Bakay, R.A.4
Stansell 3rd, J.5
Gasmi, M.6
Bartus, R.T.7
-
68
-
-
33745003683
-
Gene transfer of trophic factors and stem cell grafting as treatments for Parkinson's disease
-
Dass B, Olanow CW, Kordower JH. Gene transfer of trophic factors and stem cell grafting as treatments for Parkinson's disease. Neurology 66(Suppl 4):S89-S103, 2006.
-
(2006)
Neurology
, vol.66
, Issue.SUPPL. 4
-
-
Dass, B.1
Olanow, C.W.2
Kordower, J.H.3
-
69
-
-
0029148448
-
Citicoline (CDP-choline): Mechanisms of action and effects in ischemic brain injury
-
D'Orlando KJ, Sandage BW Jr. Citicoline (CDP-choline): mechanisms of action and effects in ischemic brain injury. Neurol Res 17:281-284, 1995.
-
(1995)
Neurol Res
, vol.17
, pp. 281-284
-
-
D'Orlando, K.J.1
Sandage Jr, B.W.2
-
70
-
-
0142026177
-
Neuroprotective effect of citicoline in 6-hydroxydopamine-lesioned rats and in 6-hydroxydopamine-treated SH-SY5Y human neuroblastoma cells
-
Barrachina M, Dominguez I, Ambrosio S, Secades J, Lozano R, Ferrer I. Neuroprotective effect of citicoline in 6-hydroxydopamine-lesioned rats and in 6-hydroxydopamine-treated SH-SY5Y human neuroblastoma cells. J Neurol Sci 215:105-110, 2003.
-
(2003)
J Neurol Sci
, vol.215
, pp. 105-110
-
-
Barrachina, M.1
Dominguez, I.2
Ambrosio, S.3
Secades, J.4
Lozano, R.5
Ferrer, I.6
-
71
-
-
21844442389
-
Cytidinediphosphocholine (CDP-choline) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly
-
CD000269
-
Fioravanti M, Yanagi M. Cytidinediphosphocholine (CDP-choline) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly. Cochrane Database Syst Rev 2:CD000269, 2005.
-
(2005)
Cochrane Database Syst Rev
, vol.2
-
-
Fioravanti, M.1
Yanagi, M.2
-
72
-
-
34548696141
-
A randomized, placebo-controlled trial of citicoline add-on therapy in outpatients with bipolar disorder and cocaine dependence
-
Brown ES, Gorman AR, Hynan LS. A randomized, placebo-controlled trial of citicoline add-on therapy in outpatients with bipolar disorder and cocaine dependence. J Clin Psychopharmacol 27:498-502, 2007.
-
(2007)
J Clin Psychopharmacol
, vol.27
, pp. 498-502
-
-
Brown, E.S.1
Gorman, A.R.2
Hynan, L.S.3
-
73
-
-
33244464506
-
Selective up-regulation of the glial Na-+-dependent glutamate transporter GLT1 by a neuroimmunophilin ligand results in neuroprotection
-
Ganel R, Ho T, Maragakis NJ, Jackson M, Steiner JP, Rothstein JD. Selective up-regulation of the glial Na-+-dependent glutamate transporter GLT1 by a neuroimmunophilin ligand results in neuroprotection. Neurobiol Dis 21:556-567, 2006.
-
(2006)
Neurobiol Dis
, vol.21
, pp. 556-567
-
-
Ganel, R.1
Ho, T.2
Maragakis, N.J.3
Jackson, M.4
Steiner, J.P.5
Rothstein, J.D.6
-
74
-
-
4344694987
-
Neuroimmunophilins: A novel drug therapy for the reversal of neurodegenerative disease?
-
Poulter MO, Payne KB, Steiner JP. Neuroimmunophilins: a novel drug therapy for the reversal of neurodegenerative disease? Neuroscience 128:1-6, 2004.
-
(2004)
Neuroscience
, vol.128
, pp. 1-6
-
-
Poulter, M.O.1
Payne, K.B.2
Steiner, J.P.3
-
75
-
-
30944443720
-
Drugs in development for Parkinson's disease: An update
-
Johnston TH, Brotchie JM. Drugs in development for Parkinson's disease: an update. Curr Opin Investig Drugs 7:25-32, 2006.
-
(2006)
Curr Opin Investig Drugs
, vol.7
, pp. 25-32
-
-
Johnston, T.H.1
Brotchie, J.M.2
-
76
-
-
33749247103
-
Novel pharmacological targets for the treatment of Parkinson's disease
-
Schapira AH, Bezard E, Brotchie J, Calon F, Collingridge GL, Ferger B, Hengerer B, Hirsch E, Jenner P, Le Novere N, Obeso JA, Schwarzschild MA, Spampinato U, Davidai G. Novel pharmacological targets for the treatment of Parkinson's disease. Nat Rev Drug Discov 5:845-854, 2006.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 845-854
-
-
Schapira, A.H.1
Bezard, E.2
Brotchie, J.3
Calon, F.4
Collingridge, G.L.5
Ferger, B.6
Hengerer, B.7
Hirsch, E.8
Jenner, P.9
Le Novere, N.10
Obeso, J.A.11
Schwarzschild, M.A.12
Spampinato, U.13
Davidai, G.14
-
77
-
-
34548348729
-
Molecular targets for treating cognitive dysfunction in schizophrenia
-
Gray JA, Roth BL. Molecular targets for treating cognitive dysfunction in schizophrenia. Schizophr Bull 33:1100-1119, 2007.
-
(2007)
Schizophr Bull
, vol.33
, pp. 1100-1119
-
-
Gray, J.A.1
Roth, B.L.2
-
78
-
-
34548362105
-
Muscarinic acetylcholine receptors: Mutant mice provide new insights for drug development
-
Wess J, Eglen RM, Gautam D. Muscarinic acetylcholine receptors: mutant mice provide new insights for drug development. Nat Rev Drug Discov 6:721-733, 2007.
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 721-733
-
-
Wess, J.1
Eglen, R.M.2
Gautam, D.3
-
79
-
-
38449111946
-
List of drugs in development for neurodegenerative diseases. Update June 2007
-
Pogacić V, Herling P. List of drugs in development for neurodegenerative diseases. Update June 2007. Neurodegener Dis 4:443-486, 2007.
-
(2007)
Neurodegener Dis
, vol.4
, pp. 443-486
-
-
Pogacić, V.1
Herling, P.2
-
80
-
-
34147181610
-
The progression of Parkinson disease: A hypothesis
-
Lang AE. The progression of Parkinson disease: a hypothesis. Neurology 68:948-952, 2007.
-
(2007)
Neurology
, vol.68
, pp. 948-952
-
-
Lang, A.E.1
-
81
-
-
34548140116
-
How migraines impact cognitive function: Findings from the Baltimore ECA
-
Vale S. How migraines impact cognitive function: findings from the Baltimore ECA. Neurology 69:810, 2007.
-
(2007)
Neurology
, vol.69
, pp. 810
-
-
Vale, S.1
-
82
-
-
34547583255
-
A cognitive bedside assessment beyond the MMSE: The Addenbrooke's Cognitive Examination
-
Bak TH, Mioshi E. A cognitive bedside assessment beyond the MMSE: the Addenbrooke's Cognitive Examination. Pract Neurol 7:245-249, 2007.
-
(2007)
Pract Neurol
, vol.7
, pp. 245-249
-
-
Bak, T.H.1
Mioshi, E.2
-
83
-
-
34147152903
-
Advances in understanding ventromedial prefrontal function: The accountant joins the executive
-
Fellows LK. Advances in understanding ventromedial prefrontal function: the accountant joins the executive. Neurology 68:991-995, 2007.
-
(2007)
Neurology
, vol.68
, pp. 991-995
-
-
Fellows, L.K.1
-
84
-
-
34247615076
-
Frontal mysteries revealed
-
Nadeau SE, Heilman KM. Frontal mysteries revealed. Neurology 68: 1450-1453, 2007.
-
(2007)
Neurology
, vol.68
, pp. 1450-1453
-
-
Nadeau, S.E.1
Heilman, K.M.2
|