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Volumn 3, Issue 7, 2008, Pages

Effect of antihypertensive therapy with alpha methyldopa on levels of angiogenic factors in pregnancies with hypertensive disorders

Author keywords

[No Author keywords available]

Indexed keywords

ENDOGLIN; FIBROBLAST GROWTH FACTOR RECEPTOR 1; METHYLDOPA; PLACENTAL GROWTH FACTOR; VASCULOTROPIN; ANGIOGENESIS INHIBITOR; ANTIHYPERTENSIVE AGENT; CELL SURFACE RECEPTOR; ENG PROTEIN, HUMAN; FLT1 PROTEIN, HUMAN; LEUKOCYTE ANTIGEN; PLACENTA PROTEIN; PRODUCT PLACENTA GROWTH FACTOR; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 1;

EID: 50649083428     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0002766     Document Type: Article
Times cited : (58)

References (43)
  • 1
    • 10744227199 scopus 로고    scopus 로고
    • Circulating angiogenic factors and the risk of preeclampsia
    • Levine RJ, Maynard SE, Qian C, Lim KH, England LJ, et al. (2004) Circulating angiogenic factors and the risk of preeclampsia. N Engl J Med 350(7): 672-683.
    • (2004) N Engl J Med , vol.350 , Issue.7 , pp. 672-683
    • Levine, R.J.1    Maynard, S.E.2    Qian, C.3    Lim, K.H.4    England, L.J.5
  • 2
    • 33748421660 scopus 로고    scopus 로고
    • Soluble endoglin and other circulating antiangiogenic factors in preeclampsia
    • Levine RJ, Lam C, Qian C, Yu KF, Maynard SE, et al. (2006) Soluble endoglin and other circulating antiangiogenic factors in preeclampsia. N Engl J Med 355(10): 992-1005.
    • (2006) N Engl J Med , vol.355 , Issue.10 , pp. 992-1005
    • Levine, R.J.1    Lam, C.2    Qian, C.3    Yu, K.F.4    Maynard, S.E.5
  • 3
    • 33744985816 scopus 로고    scopus 로고
    • Soluble endoglin contributes to the pathogenesis of preeclampsia
    • Venkatesha S, Toporsian M, Lam C, Hanai J, Mammoto T, et al. (2006) Soluble endoglin contributes to the pathogenesis of preeclampsia. Nat Med 12(6): 642-649.
    • (2006) Nat Med , vol.12 , Issue.6 , pp. 642-649
    • Venkatesha, S.1    Toporsian, M.2    Lam, C.3    Hanai, J.4    Mammoto, T.5
  • 4
    • 0037373006 scopus 로고    scopus 로고
    • Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia
    • Maynard SE, Min JY, Merchart J, Lim KH, Li J, et al. (2003) Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. J Clin Invest 111(5): 649-658.
    • (2003) J Clin Invest , vol.111 , Issue.5 , pp. 649-658
    • Maynard, S.E.1    Min, J.Y.2    Merchart, J.3    Lim, K.H.4    Li, J.5
  • 5
    • 7244238090 scopus 로고    scopus 로고
    • Elevated placental soluble vascular endothelial growth factor receptor-1 inhibits angiogenesis in preeclampsia
    • Ahmad S, Ahmed A (2004) Elevated placental soluble vascular endothelial growth factor receptor-1 inhibits angiogenesis in preeclampsia. Circ Res 95(9): 884-891.
    • (2004) Circ Res , vol.95 , Issue.9 , pp. 884-891
    • Ahmad, S.1    Ahmed, A.2
  • 6
    • 34250858133 scopus 로고    scopus 로고
    • Sequential changes in antiangiogenic factors in early pregnancy and risk of developing preeclampsia
    • Rana S, Karumanchi SA, Levine RJ, Venkatesha. S, Rauh-Hain JA, et al. (2007) Sequential changes in antiangiogenic factors in early pregnancy and risk of developing preeclampsia. Hypertension 50(1): 137-142.
    • (2007) Hypertension , vol.50 , Issue.1 , pp. 137-142
    • Rana, S.1    Karumanchi, S.A.2    Levine, R.J.3    Venkatesha, S.4    Rauh-Hain, J.A.5
  • 7
    • 19944426139 scopus 로고    scopus 로고
    • Urinary placental growth factor and risk of preeclampsia
    • Levine RJ, Thadhani R, Qian C, Lam C, Lim KH, et al. (2005) Urinary placental growth factor and risk of preeclampsia. JAMA 293(1): 77-85.
    • (2005) JAMA , vol.293 , Issue.1 , pp. 77-85
    • Levine, R.J.1    Thadhani, R.2    Qian, C.3    Lam, C.4    Lim, K.H.5
  • 8
    • 37849021866 scopus 로고    scopus 로고
    • A longitudinal study of angiogenic (placental growth factor) and anti-angiogenic (soluble endoglin and soluble vascular endothelial growth factor receptor-1) factors in normal pregnancy and patients destined to develop preeclampsia and deliver a small for gestational age neonate
    • Romero R, Nien JK, Espinoza J, Todem D, Fu W, et al. (2008) A longitudinal study of angiogenic (placental growth factor) and anti-angiogenic (soluble endoglin and soluble vascular endothelial growth factor receptor-1) factors in normal pregnancy and patients destined to develop preeclampsia and deliver a small for gestational age neonate. J Matern Fetal Neonatal Med 21(1): 9-23.
    • (2008) J Matern Fetal Neonatal Med , vol.21 , Issue.1 , pp. 9-23
    • Romero, R.1    Nien, J.K.2    Espinoza, J.3    Todem, D.4    Fu, W.5
  • 9
    • 24044460090 scopus 로고    scopus 로고
    • Evidence supporting that the excess of the sVEGFR-1 concentration in maternal plasma in preeclampsia has a uterine origin
    • Bujold E, Romero R, Chaiworapongsa T, Kim YM, Kim GJ, et al. (2005) Evidence supporting that the excess of the sVEGFR-1 concentration in maternal plasma in preeclampsia has a uterine origin. J Matern Fetal Neonatal Med 18(1): 9-16.
    • (2005) J Matern Fetal Neonatal Med , vol.18 , Issue.1 , pp. 9-16
    • Bujold, E.1    Romero, R.2    Chaiworapongsa, T.3    Kim, Y.M.4    Kim, G.J.5
  • 10
    • 0034007818 scopus 로고    scopus 로고
    • Release and complex formation of soluble VEGFR-1 from endothelial cells and biological fluids
    • Hornig C, Barleon B, Ahmad S, Vuorela P, Ahmed A, et al. (2000) Release and complex formation of soluble VEGFR-1 from endothelial cells and biological fluids. Lab Invest 80(4): 443-454.
    • (2000) Lab Invest , vol.80 , Issue.4 , pp. 443-454
    • Hornig, C.1    Barleon, B.2    Ahmad, S.3    Vuorela, P.4    Ahmed, A.5
  • 11
    • 0030582384 scopus 로고    scopus 로고
    • Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR
    • Kendall RL, Wang G, Thomas KA (1996) Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR. Biochem Biophys Res Commun 226(2): 324-328.
    • (1996) Biochem Biophys Res Commun , vol.226 , Issue.2 , pp. 324-328
    • Kendall, R.L.1    Wang, G.2    Thomas, K.A.3
  • 12
    • 21444452423 scopus 로고    scopus 로고
    • Extra-placental expression of vascular endothelial growth factor receptor-1, (Flt-1) and soluble Flt-1 (sFlt-1), by peripheral blood mononuclear cells (PBMCs) in normotensive and preeclamptic pregnant women
    • Rajakumar A, Michael HM, Rajakumar PA, Shibata E, Hubel CA, et al. (2005) Extra-placental expression of vascular endothelial growth factor receptor-1, (Flt-1) and soluble Flt-1 (sFlt-1), by peripheral blood mononuclear cells (PBMCs) in normotensive and preeclamptic pregnant women. Placenta 26(7): 563-573.
    • (2005) Placenta , vol.26 , Issue.7 , pp. 563-573
    • Rajakumar, A.1    Michael, H.M.2    Rajakumar, P.A.3    Shibata, E.4    Hubel, C.A.5
  • 13
    • 0033136689 scopus 로고    scopus 로고
    • Expression of normal and truncated forms or human endoglin
    • Raab U, Velasco B, Lastres P, Letamendia A, Cales C, et al. (1999) Expression of normal and truncated forms or human endoglin. Biochem J 339: 579-588.
    • (1999) Biochem J , vol.339 , pp. 579-588
    • Raab, U.1    Velasco, B.2    Lastres, P.3    Letamendia, A.4    Cales, C.5
  • 14
    • 0032830326 scopus 로고    scopus 로고
    • Endoglin is expressed in the chicken vasculature and is involved in angiogenesis
    • Raab U, Lastres P, Arevalo MA, Lopez-Novoa JM, Cabanas C, et al. (1999) Endoglin is expressed in the chicken vasculature and is involved in angiogenesis. FEBS Lett 459(2): 249-254.
    • (1999) FEBS Lett , vol.459 , Issue.2 , pp. 249-254
    • Raab, U.1    Lastres, P.2    Arevalo, M.A.3    Lopez-Novoa, J.M.4    Cabanas, C.5
  • 15
    • 33646569993 scopus 로고    scopus 로고
    • Biology of vascular endothelial growth factors
    • Roy H, Bhardwaj S, Yla-Herttuala S (2006) Biology of vascular endothelial growth factors. FEBS Lett 580(12): 2879-2887.
    • (2006) FEBS Lett , vol.580 , Issue.12 , pp. 2879-2887
    • Roy, H.1    Bhardwaj, S.2    Yla-Herttuala, S.3
  • 16
    • 0031044769 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor and placenta growth factor in human placenta
    • Vuorela P, Hatva E, Lymboussaki A, Kaipainen A, Joukov V, et al. (1997) Expression of vascular endothelial growth factor and placenta growth factor in human placenta. Biol Reprod 56(2): 489-494.
    • (1997) Biol Reprod , vol.56 , Issue.2 , pp. 489-494
    • Vuorela, P.1    Hatva, E.2    Lymboussaki, A.3    Kaipainen, A.4    Joukov, V.5
  • 17
    • 0347477351 scopus 로고    scopus 로고
    • Localization of vascular endothelial growth factor in the zona pellucida of developing ovarian follicles in the rat: A possible role in destiny of follicles
    • Celik-Ozenci C, Akkoyunlu G, Kayisli UA, Arici A, Demir R (2003) Localization of vascular endothelial growth factor in the zona pellucida of developing ovarian follicles in the rat: a possible role in destiny of follicles. Histochem Cell Biol 120(5): 383-390.
    • (2003) Histochem Cell Biol , vol.120 , Issue.5 , pp. 383-390
    • Celik-Ozenci, C.1    Akkoyunlu, G.2    Kayisli, U.A.3    Arici, A.4    Demir, R.5
  • 18
    • 1542316748 scopus 로고    scopus 로고
    • Expressions of VEGF and its receptors in rat corpus luteum during interferon alpha administration in early and pseudopregnancy
    • Celik-Ozenci C, Akkoyunlu G, Korgun ET, Savas B, Demir R (2004) Expressions of VEGF and its receptors in rat corpus luteum during interferon alpha administration in early and pseudopregnancy. Mol Reprod Dev 67(4): 414-423.
    • (2004) Mol Reprod Dev , vol.67 , Issue.4 , pp. 414-423
    • Celik-Ozenci, C.1    Akkoyunlu, G.2    Korgun, E.T.3    Savas, B.4    Demir, R.5
  • 19
    • 0026052391 scopus 로고
    • Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor
    • Maglione D, Guerriero V, Viglietto G, li-Bovi P, Persico MG (1991) Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor. Proc Natl Acad Sci U S A 88(20): 9267-9271.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , Issue.20 , pp. 9267-9271
    • Maglione, D.1    Guerriero, V.2    Viglietto, G.3    li-Bovi, P.4    Persico, M.G.5
  • 20
    • 0027462877 scopus 로고
    • Two alternative mRNAs coding for the angiogenic factor, placenta growth factor (PIGF), are transcribed from a single gene of chromosome 14
    • Maglione D, Guerriero V, Viglietto G, Ferraro MG, Aprelikova, O, et al. (1993) Two alternative mRNAs coding for the angiogenic factor, placenta growth factor (PIGF), are transcribed from a single gene of chromosome 14. Oncogene 8(4): 925-931.
    • (1993) Oncogene , vol.8 , Issue.4 , pp. 925-931
    • Maglione, D.1    Guerriero, V.2    Viglietto, G.3    Ferraro, M.G.4    Aprelikova, O.5
  • 21
    • 0028868639 scopus 로고
    • Upregulation of vascular endothelial growth factor (VEGF) and downregulation of placenta growth factor (PIGF) associated with malignancy in human thyroid tumors and cell lines
    • Viglietto G, Maglione D, Rambaldi M, Cerutti J, Romano A, et al. (1995) Upregulation of vascular endothelial growth factor (VEGF) and downregulation of placenta growth factor (PIGF) associated with malignancy in human thyroid tumors and cell lines. Oncogene 11(8): 1569-1579.
    • (1995) Oncogene , vol.11 , Issue.8 , pp. 1569-1579
    • Viglietto, G.1    Maglione, D.2    Rambaldi, M.3    Cerutti, J.4    Romano, A.5
  • 22
    • 0032439247 scopus 로고    scopus 로고
    • Comparison of expression patterns for placenta growth factor, vascular endothelial growth factor (VEGF), VEGF-B and VEGF-C in the human placenta throughout gestation
    • Clark DE, Smith SK, Licence D, Evans AL, Charnock-Jones DS (1998) Comparison of expression patterns for placenta growth factor, vascular endothelial growth factor (VEGF), VEGF-B and VEGF-C in the human placenta throughout gestation. J Endocrinol 159(3): 459-467.
    • (1998) J Endocrinol , vol.159 , Issue.3 , pp. 459-467
    • Clark, D.E.1    Smith, S.K.2    Licence, D.3    Evans, A.L.4    Charnock-Jones, D.S.5
  • 23
    • 0035313555 scopus 로고    scopus 로고
    • Erythroblasts are a source of angiogenic factors
    • Tordjman R, Delaire S, Plouet J, Ting S, Gaulard P, et al. (2001) Erythroblasts are a source of angiogenic factors. Blood 97(7): 1968-1974.
    • (2001) Blood , vol.97 , Issue.7 , pp. 1968-1974
    • Tordjman, R.1    Delaire, S.2    Plouet, J.3    Ting, S.4    Gaulard, P.5
  • 24
    • 0033824607 scopus 로고    scopus 로고
    • Placenta growth factor is induced in human keratinocytes during wound healing
    • Failla CM, Odorisio T, Cianfarani F, Schietroma C, Puddu P, et al. (2000) Placenta growth factor is induced in human keratinocytes during wound healing. J Invest Dermatol 115(3): 388-395.
    • (2000) J Invest Dermatol , vol.115 , Issue.3 , pp. 388-395
    • Failla, C.M.1    Odorisio, T.2    Cianfarani, F.3    Schietroma, C.4    Puddu, P.5
  • 26
    • 0031593635 scopus 로고    scopus 로고
    • Relationship between imidazoline and alpha2-adrenoceptors involved in the sympatho-inhibitory actions of centrally acting antihypertensive agents
    • Head GA, Chan CK, Burke SL (1998) Relationship between imidazoline and alpha2-adrenoceptors involved in the sympatho-inhibitory actions of centrally acting antihypertensive agents. J Auton Nerv Syst 72(2-3): 163-169.
    • (1998) J Auton Nerv Syst , vol.72 , Issue.2-3 , pp. 163-169
    • Head, G.A.1    Chan, C.K.2    Burke, S.L.3
  • 27
    • 0032775823 scopus 로고    scopus 로고
    • Central imidazoline- and alpha 2-receptors involved in the cardiovascular actions of centrally acting antihypertensive agents
    • Head GA (1999) Central imidazoline- and alpha 2-receptors involved in the cardiovascular actions of centrally acting antihypertensive agents. Ann N Y Acad Sci 881: 279-286.
    • (1999) Ann N Y Acad Sci , vol.881 , pp. 279-286
    • Head, G.A.1
  • 28
    • 0028285218 scopus 로고
    • Correlation between beta- and alpha-adrenergic receptor concentrations in human placenta
    • Falkay G, Melis K, Kovacs L (1994) Correlation between beta- and alpha-adrenergic receptor concentrations in human placenta. J Recept Res 14(3-4): 187-195.
    • (1994) J Recept Res , vol.14 , Issue.3-4 , pp. 187-195
    • Falkay, G.1    Melis, K.2    Kovacs, L.3
  • 29
    • 0033675166 scopus 로고    scopus 로고
    • Contribution of differently localized alpha 2- and beta-adrenoceptors in the modulation of TNF-alpha and IL-10 production in endotoxemic mice
    • Szelenyi J, Kiss JP, Puskas E, Szelenyi M, Vizi ES (2000) Contribution of differently localized alpha 2- and beta-adrenoceptors in the modulation of TNF-alpha and IL-10 production in endotoxemic mice. Ann N Y Acad Sci 917: 145-153.
    • (2000) Ann N Y Acad Sci , vol.917 , pp. 145-153
    • Szelenyi, J.1    Kiss, J.P.2    Puskas, E.3    Szelenyi, M.4    Vizi, E.S.5
  • 30
    • 0035869145 scopus 로고    scopus 로고
    • Plasma levels of vascular endothelial growth factor and its soluble receptor (sFlt-1) in essential hypertension
    • 805-807
    • Belgore FM, Blann AD, Li-Saw-Hee FL, Beevers DG, Lip GY (2001) Plasma levels of vascular endothelial growth factor and its soluble receptor (sFlt-1) in essential hypertension. Am J Cardiol 87(6): 805-807, A9.
    • (2001) Am J Cardiol , vol.87 , Issue.6
    • Belgore, F.M.1    Blann, A.D.2    Li-Saw-Hee, F.L.3    Beevers, D.G.4    Lip, G.Y.5
  • 31
    • 0034916930 scopus 로고    scopus 로고
    • The classification and diagnosis of the hypertensive disorders of pregnancy: Statement from the International Society for the Study of Hypertension in Pregnancy (ISSHP)
    • Brown MA, Lindheimer MD, de Swiet M, Van AA, Moutquin JM (2001) The classification and diagnosis of the hypertensive disorders of pregnancy: statement from the International Society for the Study of Hypertension in Pregnancy (ISSHP). Hypertens Pregnancy 20(1): IX-XIV.
    • (2001) Hypertens Pregnancy , vol.20 , Issue.1
    • Brown, M.A.1    Lindheimer, M.D.2    de Swiet, M.3    Van, A.A.4    Moutquin, J.M.5
  • 32
    • 0037341925 scopus 로고    scopus 로고
    • Summary of the NHLBI Working Group on Research on Hypertension During Pregnancy
    • Roberts JM, Pearson G, Cutler J, Lindheimer M (2003) Summary of the NHLBI Working Group on Research on Hypertension During Pregnancy. Hypertension 41(3): 437-45.
    • (2003) Hypertension , vol.41 , Issue.3 , pp. 437-445
    • Roberts, J.M.1    Pearson, G.2    Cutler, J.3    Lindheimer, M.4
  • 33
    • 0033334764 scopus 로고    scopus 로고
    • Alternative splicing of vascular endothelial growth factor (VEGF)-R1 (FLT-1) pre-mRNA is important for the regulation of VEGF activity
    • He Y, Smith SK, Day KA, Clark DE, Licence DR, et al. (1999) Alternative splicing of vascular endothelial growth factor (VEGF)-R1 (FLT-1) pre-mRNA is important for the regulation of VEGF activity. Mol Endocrinol. 13(4): 537-545.
    • (1999) Mol Endocrinol , vol.13 , Issue.4 , pp. 537-545
    • He, Y.1    Smith, S.K.2    Day, K.A.3    Clark, D.E.4    Licence, D.R.5
  • 34
    • 0015076792 scopus 로고
    • Evidence that the hypotensive action of methyldopa is mediated by central actions of methylnoradrenaline
    • Henning M, Rubenson A (1971) Evidence that the hypotensive action of methyldopa is mediated by central actions of methylnoradrenaline. J Pharm Pharmacol 23(6): 407-11.
    • (1971) J Pharm Pharmacol , vol.23 , Issue.6 , pp. 407-411
    • Henning, M.1    Rubenson, A.2
  • 35
    • 0015595142 scopus 로고
    • The mechanism of the antihypertensive action of -methyldopa in hypertensive rats
    • Day MD, Roach AG, Whiting RL (1973) The mechanism of the antihypertensive action of -methyldopa in hypertensive rats. Eur J Pharmacol 21(3): 271-280.
    • (1973) Eur J Pharmacol , vol.21 , Issue.3 , pp. 271-280
    • Day, M.D.1    Roach, A.G.2    Whiting, R.L.3
  • 36
    • 0021686878 scopus 로고
    • Role of alpha adrenoceptors in hypertension and in antihypertensive drug treatment
    • Van Zwieten, PA, Timmermans PB, Van BP (1984) Role of alpha adrenoceptors in hypertension and in antihypertensive drug treatment. Am J Med 77(4A): 17-25.
    • (1984) Am J Med , vol.77 , Issue.4 A , pp. 17-25
    • Van Zwieten, P.A.1    Timmermans, P.B.2    Van, B.P.3
  • 37
    • 0021049949 scopus 로고
    • Differential regulation of alpha-adrenergic receptor subclasses by gonadal steroids in human myometrium
    • Bottari SP, Vokaer A, Kaivez E, Lescrainier JP, Vauquelin GP (1983) Differential regulation of alpha-adrenergic receptor subclasses by gonadal steroids in human myometrium. J Clin Endocrinol Metab 57(5): 937-941.
    • (1983) J Clin Endocrinol Metab , vol.57 , Issue.5 , pp. 937-941
    • Bottari, S.P.1    Vokaer, A.2    Kaivez, E.3    Lescrainier, J.P.4    Vauquelin, G.P.5
  • 38
    • 0028168804 scopus 로고
    • Expression of two alpha 2-adrenergic receptor subtypes in human placenta: Evidence from direct binding studies
    • Falkay G, Kovacs L (1994) Expression of two alpha 2-adrenergic receptor subtypes in human placenta: evidence from direct binding studies. Placenta 15(6): 661-668.
    • (1994) Placenta , vol.15 , Issue.6 , pp. 661-668
    • Falkay, G.1    Kovacs, L.2
  • 39
    • 0032905215 scopus 로고    scopus 로고
    • alpha-2 and imidazoline receptor agonists. Their pharmacology and therapeutic role
    • Khan ZP, Ferguson CN, Jones RM (1999) alpha-2 and imidazoline receptor agonists. Their pharmacology and therapeutic role. Anaesthesia 54(2): 146-165.
    • (1999) Anaesthesia , vol.54 , Issue.2 , pp. 146-165
    • Khan, Z.P.1    Ferguson, C.N.2    Jones, R.M.3
  • 40
    • 0023062991 scopus 로고
    • G proteins: Transducers of receptor-generated signals
    • Gilman AG (1987) G proteins: transducers of receptor-generated signals. Annu Rev Biochem 56: 615-649.
    • (1987) Annu Rev Biochem , vol.56 , pp. 615-649
    • Gilman, A.G.1
  • 41
    • 0028880451 scopus 로고
    • A novel promoter for vascular endothelial growth factor receptor (flt-1) that confers endothelial-specific gene expression
    • Morishita K, Johnson DE, Williams LT (1995) A novel promoter for vascular endothelial growth factor receptor (flt-1) that confers endothelial-specific gene expression. J Biol Chem 270(46): 27948-27953.
    • (1995) J Biol Chem , vol.270 , Issue.46 , pp. 27948-27953
    • Morishita, K.1    Johnson, D.E.2    Williams, L.T.3
  • 42
    • 0029807470 scopus 로고    scopus 로고
    • A cAMP response element and an Ets motif are involved in the transcriptional regulation of flt-1 tyrosine kinase (vascular endothelial growth factor receptor 1) gene
    • Wakiya Y, Begue A, Stehelin D, Shibuya M (1996) A cAMP response element and an Ets motif are involved in the transcriptional regulation of flt-1 tyrosine kinase (vascular endothelial growth factor receptor 1) gene. J Biol Chem 271(48): 30823-30828.
    • (1996) J Biol Chem , vol.271 , Issue.48 , pp. 30823-30828
    • Wakiya, Y.1    Begue, A.2    Stehelin, D.3    Shibuya, M.4
  • 43
    • 34848877832 scopus 로고    scopus 로고
    • Upregulation of soluble vascular endothelial growth factor receptor 1 contributes to angiogenesis defects in the placenta of alpha 2B-adrenaceptor deficient mice
    • Muthig V, Gilsbach R, Haubold M, Philipp M, Ivacevic, T, et al. (2007) Upregulation of soluble vascular endothelial growth factor receptor 1 contributes to angiogenesis defects in the placenta of alpha 2B-adrenaceptor deficient mice. Circ Res 101(7): 682-691.
    • (2007) Circ Res , vol.101 , Issue.7 , pp. 682-691
    • Muthig, V.1    Gilsbach, R.2    Haubold, M.3    Philipp, M.4    Ivacevic, T.5


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