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Volumn 80, Issue 4, 2000, Pages 443-454

Release and complex formation of soluble VEGFR-1 from endothelial cells and biological fluids

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH FACTOR; MEMBRANE RECEPTOR; TYROSINE KINASE RECEPTOR; VASCULOTROPIN; VASCULOTROPIN RECEPTOR;

EID: 0034007818     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: 10.1038/labinvest.3780050     Document Type: Article
Times cited : (204)

References (41)
  • 1
    • 0030870623 scopus 로고    scopus 로고
    • Placental insufficiency: Hypoxia or hyperoxia?
    • Ahmed A and Kilby MD (1997). Placental insufficiency: Hypoxia or hyperoxia? Lancet 350:826-827.
    • (1997) Lancet , vol.350 , pp. 826-827
    • Ahmed, A.1    Kilby, M.D.2
  • 2
    • 0030975770 scopus 로고    scopus 로고
    • Role of VEGFR-1 (Flt-1) in mediating calcium-dependent nitric oxide release and limiting DNA synthesis in human trophoblast cells
    • Ahmed A, Dunk C, Kniss D, and Wilkes M (1997). Role of VEGFR-1 (Flt-1) in mediating calcium-dependent nitric oxide release and limiting DNA synthesis in human trophoblast cells. Lab Invest 76:779-791.
    • (1997) Lab Invest , vol.76 , pp. 779-791
    • Ahmed, A.1    Dunk, C.2    Kniss, D.3    Wilkes, M.4
  • 3
    • 0031001133 scopus 로고    scopus 로고
    • Variation in detection of VEGF in maternal serum by immunoassay and the possible influence of binding proteins
    • Anthony FW, Evans PW, Wheeler T, and Wood PJ (1997). Variation in detection of VEGF in maternal serum by immunoassay and the possible influence of binding proteins. Ann Clin Biochem 34:276-280.
    • (1997) Ann Clin Biochem , vol.34 , pp. 276-280
    • Anthony, F.W.1    Evans, P.W.2    Wheeler, T.3    Wood, P.J.4
  • 5
    • 0028281244 scopus 로고
    • Differential expression of the two VEGF receptors fit and KDR in placenta and vascular endothelial cells
    • Barleon B, Hauser S, Schöllmann C, Weindel K, Marmè D, Yayon A, and Weich HA (1994). Differential expression of the two VEGF receptors fit and KDR in placenta and vascular endothelial cells. J Cell Biochem 54:56-66.
    • (1994) J Cell Biochem , vol.54 , pp. 56-66
    • Barleon, B.1    Hauser, S.2    Schöllmann, C.3    Weindel, K.4    Marmè, D.5    Yayon, A.6    Weich, H.A.7
  • 6
    • 0030932842 scopus 로고    scopus 로고
    • Mapping of the sites for ligand binding and receptor dimerization at the extracellular domain of the vascular endothelial growth factor receptor FLT-1
    • Barleon B, Totzke F, Herzog C, Blanke S, Kremmer E, Siemeister G, Marmè D, and Martiny-Baron G (1997). Mapping of the sites for ligand binding and receptor dimerization at the extracellular domain of the vascular endothelial growth factor receptor FLT-1. J Biol Chem 272:10382-10388.
    • (1997) J Biol Chem , vol.272 , pp. 10382-10388
    • Barleon, B.1    Totzke, F.2    Herzog, C.3    Blanke, S.4    Kremmer, E.5    Siemeister, G.6    Marmè, D.7    Martiny-Baron, G.8
  • 8
    • 0342263694 scopus 로고    scopus 로고
    • Placental angiogenesis: The role of the VEGF family of proteins
    • Clark DE and Charnock-Jones DS (1999). Placental angiogenesis: The role of the VEGF family of proteins. Angiogenesis 2:309-318.
    • (1999) Angiogenesis , vol.2 , pp. 309-318
    • Clark, D.E.1    Charnock-Jones, D.S.2
  • 9
    • 0024949847 scopus 로고
    • Factors affecting gas transfer across the placenta and the oxygen supply to the fetus
    • Carter AM (1989). Factors affecting gas transfer across the placenta and the oxygen supply to the fetus. J Dev Physiol 12:305-322.
    • (1989) J Dev Physiol , vol.12 , pp. 305-322
    • Carter, A.M.1
  • 10
    • 0031695198 scopus 로고    scopus 로고
    • Functions of the VEGFR-1 (FLT-1) in the vasculature
    • Clauss M (1998). Functions of the VEGFR-1 (FLT-1) in the vasculature. Trends Cardiovasc Med 8:241-245.
    • (1998) Trends Cardiovasc Med , vol.8 , pp. 241-245
    • Clauss, M.1
  • 11
    • 0032818583 scopus 로고    scopus 로고
    • Expression and localization of placenta growth factor and PIGF receptors in human meningiomas
    • Donnini S, Machein MR, Plate KH, and Weich HA (1999). Expression and localization of placenta growth factor and PIGF receptors in human meningiomas. J Pathol 189:66-71.
    • (1999) J Pathol , vol.189 , pp. 66-71
    • Donnini, S.1    Machein, M.R.2    Plate, K.H.3    Weich, H.A.4
  • 12
    • 0031039243 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor
    • Ferrara N and Davis-Smyth T (1997). The biology of vascular endothelial growth factor. Endocrinol Rev 18:4-25.
    • (1997) Endocrinol Rev , vol.18 , pp. 4-25
    • Ferrara, N.1    Davis-Smyth, T.2
  • 14
    • 1842346472 scopus 로고    scopus 로고
    • Molecular mechanisms of vasculogenesis and embryonic angiogenesis
    • Flamme I, Frölich T, and Risau W (1997). Molecular mechanisms of vasculogenesis and embryonic angiogenesis. J Cell Physiol 173:206-210.
    • (1997) J Cell Physiol , vol.173 , pp. 206-210
    • Flamme, I.1    Frölich, T.2    Risau, W.3
  • 15
    • 0029021660 scopus 로고
    • Role of Flt-1 receptor tyrosine kinase in regulation of assembly of vascular endothelium
    • Fong GH, Rassant J, Gertenstein M, and Breitman M (1995). Role of Flt-1 receptor tyrosine kinase in regulation of assembly of vascular endothelium. Nature 376:66-67.
    • (1995) Nature , vol.376 , pp. 66-67
    • Fong, G.H.1    Rassant, J.2    Gertenstein, M.3    Breitman, M.4
  • 17
    • 0030751493 scopus 로고    scopus 로고
    • Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes
    • Gerber HP, Condorelli F, Park J, and Ferrara N (1997). Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. J Biol Chem 272: 23659-23667.
    • (1997) J Biol Chem , vol.272 , pp. 23659-23667
    • Gerber, H.P.1    Condorelli, F.2    Park, J.3    Ferrara, N.4
  • 18
    • 0027745824 scopus 로고
    • A heparin-binding form of placenta growth factor (PIGF-2) is expressed in human umbilical vein endothelial cells and in placenta
    • Hauser S and Weich HA (1993). A heparin-binding form of placenta growth factor (PIGF-2) is expressed in human umbilical vein endothelial cells and in placenta. Growth Factors 9:259-268.
    • (1993) Growth Factors , vol.9 , pp. 259-268
    • Hauser, S.1    Weich, H.A.2
  • 19
    • 0033334764 scopus 로고    scopus 로고
    • Alternative splicing of vascular endothelial growth factor (VEGF)-R1 (Flt-1) pre-mRNA is important for the regulation of VEGF activity
    • He Y, Smith SK, Day KA, Clark DE, Licence DR, and Charnock-Jones DS (1999). Alternative splicing of vascular endothelial growth factor (VEGF)-R1 (Flt-1) pre-mRNA is important for the regulation of VEGF activity. Mol Endocr 13:537-545.
    • (1999) Mol Endocr , vol.13 , pp. 537-545
    • He, Y.1    Smith, S.K.2    Day, K.A.3    Clark, D.E.4    Licence, D.R.5    Charnock-Jones, D.S.6
  • 20
    • 0032482978 scopus 로고    scopus 로고
    • Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice
    • Hiratsuka S, Minowa O, Kuno J, Noda T, and Shibuya M (1998). Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice. Proc Natl Acad Sci USA 95:9349-9354.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9349-9354
    • Hiratsuka, S.1    Minowa, O.2    Kuno, J.3    Noda, T.4    Shibuya, M.5
  • 21
    • 0032795396 scopus 로고    scopus 로고
    • Detection and quantification of complexed and free soluble human vascular endothelial growth factor receptor-1 (sVEGFR-1) by ELISA
    • Hornig C, Behn T, Bartsch W, Yayon A, and Weich HA (1999). Detection and quantification of complexed and free soluble human vascular endothelial growth factor receptor-1 (sVEGFR-1) by ELISA. J Immunol Meth 226:169-177.
    • (1999) J Immunol Meth , vol.226 , pp. 169-177
    • Hornig, C.1    Behn, T.2    Bartsch, W.3    Yayon, A.4    Weich, H.A.5
  • 22
    • 0027421333 scopus 로고
    • Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor
    • Kendall RL and Thomas KA (1993). Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor. Proc Natl Acad Sci USA 90: 10705-10709.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10705-10709
    • Kendall, R.L.1    Thomas, K.A.2
  • 23
    • 0030582384 scopus 로고    scopus 로고
    • Identification of a natural soluble form of the vascular endothelial growth factor receptor FLT-1 and its heterodimerization with KDR
    • Kendall RL, Wang G, and Thomas KA (1996). Identification of a natural soluble form of the vascular endothelial growth factor receptor FLT-1 and its heterodimerization with KDR. Biochem Biophys Res Commun 226:324-328.
    • (1996) Biochem Biophys Res Commun , vol.226 , pp. 324-328
    • Kendall, R.L.1    Wang, G.2    Thomas, K.A.3
  • 24
    • 0033059578 scopus 로고    scopus 로고
    • Hypoxia down-regulates placenta growth factor whereas fetal growth restriction up-regulates placenta growth factor expression: Molecular evidence for placental hyperoxia in intrauterine growth restriction
    • Khaliq A, Dunk CE, Shams M, Li XF, Whittle MJ, Weich H, and Ahmed A (1999). Hypoxia down-regulates placenta growth factor whereas fetal growth restriction up-regulates placenta growth factor expression: Molecular evidence for placental hyperoxia in intrauterine growth restriction. Lab Invest 79:151-170.
    • (1999) Lab Invest , vol.79 , pp. 151-170
    • Khaliq, A.1    Dunk, C.E.2    Shams, M.3    Li, X.F.4    Whittle, M.J.5    Weich, H.6    Ahmed, A.7
  • 25
    • 0032570774 scopus 로고    scopus 로고
    • Genomic organization of the flt-1 gene encoding for vascular endothelial growth factor (VEGF) receptor-1 suggests an intimate evolutionary relationship between the 7-lg and the 5-lg tyrosine kinase receptors
    • Kondo K, Hiratsuka S, Subbalakshmi E, Matsushime H, and Shibuya M (1998). Genomic organization of the flt-1 gene encoding for vascular endothelial growth factor (VEGF) receptor-1 suggests an intimate evolutionary relationship between the 7-lg and the 5-lg tyrosine kinase receptors. Gene 208:297-305.
    • (1998) Gene , vol.208 , pp. 297-305
    • Kondo, K.1    Hiratsuka, S.2    Subbalakshmi, E.3    Matsushime, H.4    Shibuya, M.5
  • 26
    • 0024818355 scopus 로고
    • Vascular endothelial growth factor is a secreted angiogenic mitogen
    • Leung DW, Cachianes G, Kuang WJ, Goeddel DV, and Ferrara N (1989). Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246:1306-1309.
    • (1989) Science , vol.246 , pp. 1306-1309
    • Leung, D.W.1    Cachianes, G.2    Kuang, W.J.3    Goeddel, D.V.4    Ferrara, N.5
  • 29
    • 0026699255 scopus 로고
    • FLT4 receptor tyrosine kinase contains seven immunoglobulin-like loops and is expressed in multiple human tissues and cell lines
    • Pajusola K, Aprelikova O, Korhonen J, Kaipainen A, Pertovaara L, Alitalo R, and Alitalo K (1992). FLT4 receptor tyrosine kinase contains seven immunoglobulin-like loops and is expressed in multiple human tissues and cell lines. Cancer Res 52:5738-5743.
    • (1992) Cancer Res , vol.52 , pp. 5738-5743
    • Pajusola, K.1    Aprelikova, O.2    Korhonen, J.3    Kaipainen, A.4    Pertovaara, L.5    Alitalo, R.6    Alitalo, K.7
  • 30
    • 0028134936 scopus 로고
    • Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR
    • Park JE, Chen HH, Winer J, Houck KA, and Ferrara N (1994). Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR. J Biol Chem 269: 25646-25654.
    • (1994) J Biol Chem , vol.269 , pp. 25646-25654
    • Park, J.E.1    Chen, H.H.2    Winer, J.3    Houck, K.A.4    Ferrara, N.5
  • 31
    • 0031867648 scopus 로고    scopus 로고
    • Differential binding characteristics and cellular inhibition by soluble VEGF receptors 1 and 2
    • Röckl W, Hecht D, Sztajer H, Waltenberger J, Yayon A, and Weich HA (1998). Differential binding characteristics and cellular inhibition by soluble VEGF receptors 1 and 2. Exp Cell Res 241:161-170.
    • (1998) Exp Cell Res , vol.241 , pp. 161-170
    • Röckl, W.1    Hecht, D.2    Sztajer, H.3    Waltenberger, J.4    Yayon, A.5    Weich, H.A.6
  • 33
    • 0028798083 scopus 로고
    • A unique signal transduction pathway for the FLT tyrosine kinase, a receptor for vascular endothelial growth factor
    • Seetharam L, Gotoh N, Maru Y, Neufeld G, Yamaguchi S, and Shibuya M (1995). A unique signal transduction pathway for the FLT tyrosine kinase, a receptor for vascular endothelial growth factor. Oncogene 10:135-147.
    • (1995) Oncogene , vol.10 , pp. 135-147
    • Seetharam, L.1    Gotoh, N.2    Maru, Y.3    Neufeld, G.4    Yamaguchi, S.5    Shibuya, M.6
  • 35
    • 0025259592 scopus 로고
    • Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family
    • Shibuya M, Yamaguchi S, Yamane A, Ikeda T, Tojo A, Matsushime H, and Sato M (1990). Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family. Oncogene 5:519-524.
    • (1990) Oncogene , vol.5 , pp. 519-524
    • Shibuya, M.1    Yamaguchi, S.2    Yamane, A.3    Ikeda, T.4    Tojo, A.5    Matsushime, H.6    Sato, M.7
  • 36
    • 0026485002 scopus 로고
    • Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
    • Shweiki D, Itin A, Soffer D, and Keshet E (1992). Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 359:843-845.
    • (1992) Nature , vol.359 , pp. 843-845
    • Shweiki, D.1    Itin, A.2    Soffer, D.3    Keshet, E.4
  • 40
    • 0033119572 scopus 로고    scopus 로고
    • Induction of vascular endothelial growth factor expression in endothelial cells by platelet-derived growth factor through the activation of phosphatidylinositol 3-kinase
    • Wang D, Huang HJS, Kazlauskas A, and Cavenee WK (1999). Induction of vascular endothelial growth factor expression in endothelial cells by platelet-derived growth factor through the activation of phosphatidylinositol 3-kinase. Cancer Res 59:1464-1472.
    • (1999) Cancer Res , vol.59 , pp. 1464-1472
    • Wang, D.1    Huang, H.J.S.2    Kazlauskas, A.3    Cavenee, W.K.4
  • 41
    • 0026751994 scopus 로고
    • Aids-associated kaposis sarcoma cells in culture express vascular endothelial growth factor
    • Weindel K, Marmé D, and Weich HA (1992). Aids-associated Kaposis sarcoma cells in culture express vascular endothelial growth factor. Biochem Biophys Res Commun 183:1167-1174.
    • (1992) Biochem Biophys Res Commun , vol.183 , pp. 1167-1174
    • Weindel, K.1    Marmé, D.2    Weich, H.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.