Contribution of α4β1 integrin to the antiallergic effect of levocabastine

Biochemical Pharmacology

Volumn 76, Issue 6, 2008, Pages 751-762

  Qasem, Ahmed R ^a   Bucolo, Claudio ^b   Baiula, Monica ^c   Spartà, Antonino ^c   Govoni, Paolo ^d   Bedini, Andrea ^c   Fascì, Domenico ^c   Spampinato, Santi ^c  

^a MEDICAL COLLEGE OF OHIO   (United States)

^b UNIVERSITY OF CATANIA   (Italy)

^c UNIVERSITY OF BOLOGNA   (Italy)

^d UNIVERSITY OF PARMA   (Italy)

Author keywords

4 1 Integrin; Allergic conjunctivitis; Cell adhesion; Eosinophil; Inhibitor; Levocabastine; VCAM 1

Indexed keywords

ANTIALLERGIC AGENT; ANTIHISTAMINIC AGENT; CHLORPHENIRAMINE; EYE DROPS; FIBRONECTIN; INTERCELLULAR ADHESION MOLECULE 1; IODINE 125; LEVOCABASTINE; VASCULAR CELL ADHESION MOLECULE 1; VERY LATE ACTIVATION ANTIGEN 4; HISTAMINE H1 RECEPTOR ANTAGONIST; PIPERIDINE DERIVATIVE;

ALLERGIC CONJUNCTIVITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN BINDING; ANTIGEN EXPRESSION; ARTICLE; ASSAY; BINDING AFFINITY; BINDING ASSAY; CELL ACTIVATION; CELL ADHESION; CELL INFILTRATION; CELL LINE; CELL SURFACE; CONTROLLED STUDY; DRUG BINDING; DRUG EFFICACY; DRUG INHIBITION; DRUG INSTILLATION; DRUG MECHANISM; DRUG TARGETING; ENDOTHELIUM CELL; EOSINOPHIL; FLOW CYTOMETRY; GUINEA PIG; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; ISOTOPE LABELING; MALE; NONHUMAN; PRIORITY JOURNAL; SCINTILLATION PROXIMITY ASSAY; VASCULAR ENDOTHELIUM; ANIMAL; CELL CULTURE; CHEMISTRY; COMPARATIVE STUDY; DRUG ANTAGONISM; LEUKEMIA CELL LINE; METABOLISM; PHYSIOLOGY; PROTEIN BINDING;

ANIMALS; ANTI-ALLERGIC AGENTS; CELLS, CULTURED; CHLORPHENIRAMINE; GUINEA PIGS; HISTAMINE H1 ANTAGONISTS, NON-SEDATING; HUMANS; INTEGRIN ALPHA4BETA1; JURKAT CELLS; MALE; PIPERIDINES; PROTEIN BINDING;

EID: 50549104175     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2008.07.007     Document Type: Article

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