Reduction of 5-(bromomethyl)-1-pyrrolinium bromides to 2-(bromomethyl)pyrrolidines and their transformation into piperidin-3-ones through an unprecedented ring expansion-oxidation protocol

Tetrahedron Letters

Volumn 49, Issue 42, 2008, Pages 6039-6042

  D'hooghe, Matthias ^a   Baele, Jan ^a   Contreras, Jan ^a   Boelens, Mark ^a   Kimpe, Norbert De ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

1 Pyrrolinium salts; 3 Hydroxypiperidines; Piperidin 3 ones; Ring expansion

Indexed keywords

3,3 DIALKYL 5 (BROMOMETHYL) 1 PYRROLINIUM BROMIDE DERIVATIVE; 4,4 DIALKYL 2 (BROMOMETHYL)PYRROLIDINE DERIVATIVE; 5,5 DIALKYL 3 HYDROXYPIPERIDINE DERIVATIVE; 5,5 DIALKYLPIPERIDIN 3 ONE DERIVATIVE; AMINE; BORANE DERIVATIVE; BORANE DIMETHYL SULFIDE; BROMINE; DICHLOROMETHANE; DIMETHYL SULFOXIDE; METHANOL; N (2,2 DIALKYL 4 PENTENYLIDENE)AMINE DERIVATIVE; PIPERIDINE DERIVATIVE; POTASSIUM CARBONATE; PYRROLIDINE DERIVATIVE; SODIUM BOROHYDRIDE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; CYCLIZATION; HYDROLYSIS; OXIDATION; REDUCTION; SUBSTITUTION REACTION;

EID: 50549099792     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2008.07.112     Document Type: Article

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