An appraisal of new variants of Dde amine protecting group for solid phase peptide synthesis

Tetrahedron Letters

Volumn 39, Issue 12, 1998, Pages 1603-1606

  Chhabra, Siri Ram ^a   Hothi, Bhupinder ^a   Evans, David J ^a   White, Peter D ^b   Bycroft, Barrie W ^a   Chan, Weng C ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b Calbiochem Novabiochem UK Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; PIPERIDINE;

ARTICLE; PEPTIDE SYNTHESIS;

EID: 0032546258     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)10828-0     Document Type: Article

References (14)

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3. 2. Bloomberg, G. B.; Askin, G.; Gargaro, A. R.; Tanner, M. J. Tetrahedron Lett. 1993, 34, 4709-4712; Brugghe, H. F.; Timmermans, H. A. M.; Van Unen, L. M. A.; Hove, G. J. T.; Van de Werken, G.; Poolman, J. T.; Hoogerhout, P. Int. J. Peptide Protein Res. 1994, 43, 166-172; Truffert, J.-C.; Lorthioir, O.; Asseline, U.; Thuong, N. T.; Brack, A. Tetrahedron Lett. 1994, 35, 2353-2356; Eichler, J.; Lucka, A.W.; Houghten, R.A. Peptide Research 1994, 7, 300-307; Dumy, P.; Eggleston I. M.; Corvigni, S.; Sila, U.; Sun, X.; Mutter, M. Tetrahedron Lett. 1995, 36, 1255-1258; Ahlborg, N. J. Immunol. Methods. 1995, 179, 269-275.
4. 2. Bloomberg, G. B.; Askin, G.; Gargaro, A. R.; Tanner, M. J. Tetrahedron Lett. 1993, 34, 4709-4712; Brugghe, H. F.; Timmermans, H. A. M.; Van Unen, L. M. A.; Hove, G. J. T.; Van de Werken, G.; Poolman, J. T.; Hoogerhout, P. Int. J. Peptide Protein Res. 1994, 43, 166-172; Truffert, J.-C.; Lorthioir, O.; Asseline, U.; Thuong, N. T.; Brack, A. Tetrahedron Lett. 1994, 35, 2353-2356; Eichler, J.; Lucka, A.W.; Houghten, R.A. Peptide Research 1994, 7, 300-307; Dumy, P.; Eggleston I. M.; Corvigni, S.; Sila, U.; Sun, X.; Mutter, M. Tetrahedron Lett. 1995, 36, 1255-1258; Ahlborg, N. J. Immunol. Methods. 1995, 179, 269-275.
5. 2. Bloomberg, G. B.; Askin, G.; Gargaro, A. R.; Tanner, M. J. Tetrahedron Lett. 1993, 34, 4709-4712; Brugghe, H. F.; Timmermans, H. A. M.; Van Unen, L. M. A.; Hove, G. J. T.; Van de Werken, G.; Poolman, J. T.; Hoogerhout, P. Int. J. Peptide Protein Res. 1994, 43, 166-172; Truffert, J.-C.; Lorthioir, O.; Asseline, U.; Thuong, N. T.; Brack, A. Tetrahedron Lett. 1994, 35, 2353-2356; Eichler, J.; Lucka, A.W.; Houghten, R.A. Peptide Research 1994, 7, 300-307; Dumy, P.; Eggleston I. M.; Corvigni, S.; Sila, U.; Sun, X.; Mutter, M. Tetrahedron Lett. 1995, 36, 1255-1258; Ahlborg, N. J. Immunol. Methods. 1995, 179, 269-275.
6. 2. Bloomberg, G. B.; Askin, G.; Gargaro, A. R.; Tanner, M. J. Tetrahedron Lett. 1993, 34, 4709-4712; Brugghe, H. F.; Timmermans, H. A. M.; Van Unen, L. M. A.; Hove, G. J. T.; Van de Werken, G.; Poolman, J. T.; Hoogerhout, P. Int. J. Peptide Protein Res. 1994, 43, 166-172; Truffert, J.-C.; Lorthioir, O.; Asseline, U.; Thuong, N. T.; Brack, A. Tetrahedron Lett. 1994, 35, 2353-2356; Eichler, J.; Lucka, A.W.; Houghten, R.A. Peptide Research 1994, 7, 300-307; Dumy, P.; Eggleston I. M.; Corvigni, S.; Sila, U.; Sun, X.; Mutter, M. Tetrahedron Lett. 1995, 36, 1255-1258; Ahlborg, N. J. Immunol. Methods. 1995, 179, 269-275.
7. 2. Bloomberg, G. B.; Askin, G.; Gargaro, A. R.; Tanner, M. J. Tetrahedron Lett. 1993, 34, 4709-4712; Brugghe, H. F.; Timmermans, H. A. M.; Van Unen, L. M. A.; Hove, G. J. T.; Van de Werken, G.; Poolman, J. T.; Hoogerhout, P. Int. J. Peptide Protein Res. 1994, 43, 166-172; Truffert, J.-C.; Lorthioir, O.; Asseline, U.; Thuong, N. T.; Brack, A. Tetrahedron Lett. 1994, 35, 2353-2356; Eichler, J.; Lucka, A.W.; Houghten, R.A. Peptide Research 1994, 7, 300-307; Dumy, P.; Eggleston I. M.; Corvigni, S.; Sila, U.; Sun, X.; Mutter, M. Tetrahedron Lett. 1995, 36, 1255-1258; Ahlborg, N. J. Immunol. Methods. 1995, 179, 269-275.
8. 3. Bycroft, B.W.; Chan, W.C.; Hone, N.D.; Millington, S.; Nash, I. J. Am. Chem. Soc. 1994, 116, 7415-7416; Nash, I.A; Bycroft, B.W.; Chan, W.C. Tetrahedron Lett., 1996, 37, 2625-2628.
9. 3. Bycroft, B.W.; Chan, W.C.; Hone, N.D.; Millington, S.; Nash, I. J. Am. Chem. Soc. 1994, 116, 7415-7416; Nash, I.A; Bycroft, B.W.; Chan, W.C. Tetrahedron Lett., 1996, 37, 2625-2628.
10. 4. Kellam, B.; Bycroft, B. W.; Chhabra, S. R. Tetrahedron Lett. 1997, 38, 4849-4852.
11. 5. Augustyns, K.; Kraas, W.; Jung, G. "A side reaction of the Dde protecting group: migration to an unprotected lysine" 24th Symposium of the European Peptide Society, September 1996, P399.
12. 6. Kellam, B.; Chan, W. C.; Chhabra, S. R.; Bycroft, B. W. Tetrahedron Lett. 1997, 38, 5391-5394.
13. 6 requires 574.70).
14. + found 585.3, requires 585.8.