Cytotoxic and genotoxic effects of methotrexate in germ cells of male Swiss mice

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 655, Issue 1-2, 2008, Pages 59-67

  Padmanabhan, S ^a   Tripathi, D N ^a   Vikram, A ^a   Ramarao, P ^a   Jena, G B ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Comet assay; Methotrexate; Mice; Sperm count; Sperm head abnormality; Testis; TUNEL assay

Indexed keywords

DNA; METHOTREXATE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASSAY; COMET ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DNA FRAGMENTATION; GENOTOXICITY; GERM CELL; HALO ASSAY; HISTOLOGY; MALE; MOUSE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; SPERMATOZOON; SPERMATOZOON COUNT; TESTIS WEIGHT;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; COMET ASSAY; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; IN SITU NICK-END LABELING; MALE; METHOTREXATE; MICE; ORGAN SIZE; SPERM COUNT; SPERM HEAD; SPERMATOZOA; TESTIS;

ANIMALIA; MUS;

EID: 50349091192     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2008.07.003     Document Type: Article

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