Quantitative structure-activity relationship studies on nitrofuranyl anti-tubercular agents

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 17, 2008, Pages 8042-8053

  Hevener, Kirk E ^a   Ball, David M ^a   Buolamwini, John K ^a   Lee, Richard E ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Anti tuberculosis drug discovery; CoMFA; Nitrofuran; PA824; QSAR; Tuberculosis

Indexed keywords

6,7 DIHYDRO 2 NITRO 6 (4 TRIFLUOROMETHOXYBENZYLOXY) 5H IMIDAZO[2,1 B][1,3]OXAZINE; NITROFURAN DERIVATIVE; NITROIMIDAZOLE DERIVATIVE; OPC 67638; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; EXTERNAL VALIDITY; INTERNAL VALIDITY; IONIZATION; LIPOPHILICITY; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; PREDICTIVE VALIDITY; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STEREOSPECIFICITY; STRUCTURE ANALYSIS; SURFACE PROPERTY;

ANTITUBERCULAR AGENTS; COMPUTER SIMULATION; DRUG DESIGN; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; NITROFURANS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; REPRODUCIBILITY OF RESULTS; STEREOISOMERISM;

MYCOBACTERIUM TUBERCULOSIS;

EID: 50349090045     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.07.070     Document Type: Article

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