Oral matrix tablet formulations for concomitant controlled release of anti-tubercular drugs: Design and in vitro evaluations

International Journal of Pharmaceutics

Volumn 362, Issue 1-2, 2008, Pages 118-125

  Hiremath, Praveen S ^a   Saha, Ranendra N ^a  

^a BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

Author keywords

Controlled release; HPC; HPMC; Isoniazid; Matrix tablets; Rifampicin

Indexed keywords

EUDRAGIT; HYDROXYPROPYLMETHYLCELLULOSE; ISONIAZID PLUS RIFAMPICIN; TUBERCULOSTATIC AGENT;

ARTICLE; CONTROLLED RELEASE FORMULATION; DIFFUSION; HYDROPHILICITY; INTESTINE FLUID; ORAL MATRIX TABLET FORMULATION; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROCESS OPTIMIZATION; SIMULATION; STOMACH JUICE; TABLET FORMULATION; TABLET FRIABILITY; TABLET HARDNESS;

ADMINISTRATION, ORAL; ANTITUBERCULAR AGENTS; DELAYED-ACTION PREPARATIONS; DRUG COMBINATIONS; ISONIAZID; RIFAMPIN; SOLUBILITY; TABLETS; TECHNOLOGY, PHARMACEUTICAL;

EID: 50249169962     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2008.06.019     Document Type: Article

References (22)

1. Ain Q., Sharma S., Garg S.K., and Khuller G.K. Role of poly (dl-lactide-co-glycolide) in the development of a sustained oral delivery system for antitubercular drug(s). Int. J. Pharm. 239 (2002) 37-46
2. Ain Q., Sharma S., Khuller G.K., and Garg S.K. Alginate-based oral drug delivery system for tuberculosis: pharmacokinetics and therapeutic effects. J. Antimicrob. Chemother. 51 (2003) 931-938
3. Alderman D.A. A review of cellulose ether in hydrophilic matrices for oral controlled release dosage forms. Int. J. Pharm. Technol. Prod. Manuf. 5 (1984) 1-9
4. Al-Taani B.M., and Tashtoush B.M. Effect of microenvironment pH of swellable and erodable buffered matrices on the release characteristics of diclofenac sodium. AAPS PharmSciTech 4 (2003) E43
5. Batyrbekov E.O., Rukhina L.B., Zhubanov B.A., Bekmukhamedova N.F., and Smailova G.A. Drug delivery systems for tuberculosis treatment. Polym. Int. 43 (1997) 317-320
6. Blomberg B., and Fourie B. Fixed dose combination drugs for tuberculosis: application in standardized treatment regimens. Drugs 63 (2003) 535-553
7. Eidus L., and Hodgkin M.M. A new isoniazid preparation designed for moderately fast and "fast" metabolizers of the drug. Arzneimittel Forsch. (Drug Res.) 25 (1975) 1077-1080
8. Ford J.L., Rubinstein M.H., and Hogan J.E. Formulation of sustained release promethazine hydrochloride tablets using hydroxypropyl methylcellulose matrices. Int. J. Pharm. 24 (1985) 327-338
9. Gohel M.C., Patel T.P., and Bariya S.H. Studies in preparetion and evaluation of pH-independent sustained-release matrix tablets of verapamil HCl using directly compressible Eudragits. Pharm. Dev. Technol. 8 (2003) 323-333
10. Hiremath S.P., and Saha R.N. Design and study of rifampicin oral controlled release formulations. Drug Deliv. 11 (2004) 311-317
11. Hiremath P.S., and Saha R.N. Oral controlled release formulations of rifampicin: Part II. Effect of formulation variables. Drug Deliv. 15 (2008) 159-168
12. Korsmeyer R.W., Gurny R., Doelker E., Buri P., and Peppas N.A. Mechanisms of solute release from porous hydrophilic polymers. Int. J. Pharm. 15 (1983) 25-35
13. Kustrin S.A., Glass B.D., Wisch M.H., and Alany R.G. Prediction of a stable microemulsion formulation for the oral delivery of a combination of antitubercular drugs using ANN methodology. Pharm. Res. 20 (2003) 1760-1765
14. Lee B.-J., Ryu S.-G., and Cui J.-H. Formulation and release characteristics of hydroxypropyl methylcellulose matrix tablet containing melatonin. Drug Dev. Ind. Pharm. 25 (1999) 493-501
15. Maggi L., Machiste E.O., Torre M.L., and Conte U. Formulation of biphasic release tablets containing slightly soluble drugs. Eur. J. Pharm. Biopharm. 48 (1999) 37-42
16. Nakagami H., and Nada M. Application of micronized insoluble cellulose to sustained release tablets. Proc. Int. Symp. Control Bioact. Mater. 15 (1988) 11-12
17. Prabhakaran D., Singh P., Jaganathan K.S., and Vyas S.P. Osmotically regulated asymmetric capsular systems for simultaneous sustained delivery of anti-tubercular drugs. J. Control Release 95 (2004) 239-248
18. Ranga Rao K.V., Padmalatha Devi K., and Buri B. Cellulose matrices for zero-order release of soluble drugs. Drug Dev. Ind. Pharm. 14 (1988) 2299-2320
19. Rao V.M., Engh K., and Qiu Y. Design of pH-independent controlled release matrix tablets for acidic drugs. Int. J. Pharm. 252 (2003) 81-86
20. Ritger P.L., and Peppas N.A. A simple equation for description of solute release. II. Fickian and anomalous release from swellable devices. J. Control Release 5 (1987) 37-42
21. Velasco M., Ford J.L., Rowe P., and Rajabi-Siahboomi A. Influence of drug:hydroxypropyl methylcellulose ratio, drug and polymer particle size and compression force on the release of diclofenac sodium from HPMC matrices. J. Control Release 57 (1999) 75-85
22. Verma M.V.S., Kaushal A.M., Garg A., and Garg S. Factors affecting mechanism and kinetics of drug release from matrix-based oral controlled drug delivery systems. Am. J. Drug Deliv. 2 (2004) 43-57